Testiste Eksprese Olan Glutatyon Peroksidaz (Gpx) Ailesi ve Reprodüktif Fonksiyonlardaki Rolleri

Agarwal A, Gharagozloo P, Sharma RK, Du Plessis SS. Effects of oxidative stress on male reproduction. World Journal of Men's Health, 2014, 32(1), 1–17.

Aitken RJ, Gibb Z, Baker MA, Drevet JR. Causes and consequences of oxidative stress in spermatozoa. Reproduction, 2014, 148(6), R115–R127.

Aitken RJ, Curry BJ. Redox regulation of human sperm function: From the physiological control of sperm capacitation to the etiology of infertility and DNA damage. Antioxidants & Redox Signaling, 2011, 14(3), 367–381.

Brigelius-Flohé R, Maiorino M. Glutathione peroxidases. Biochimica et Biophysica Acta – General Subjects, 2013, 1830(5), 3289–3303.

Chabory E, Damon C, Lenoir A, Henry-Berger J, Vernet P, Cadet R, et al. Mammalian glutathione peroxidases control acquisition and maintenance of spermatozoa integrity. Journal of Animal Science, 2010, 88(4), 1321–1331.

Drevet JR. The antioxidant glutathione peroxidase family and spermatozoa: a complex story. Molecular and Cellular Endocrinology, 2006, 250(1–2), 70–79.

Dutta S, Sengupta P, Slama P, Roychoudhury S. Oxidative stress, testicular inflammatory pathways, and male reproduction. International Journal of Molecular Sciences, 2021, 22(18), 10043.

Flohé L, Toppo S, Orian L. The glutathione peroxidase family: Discoveries and mechanism. Free Radical Biology and Medicine, 2022, 187, 113–122.

Flohé L, Günzler WA. Assays of glutathione peroxidase. Methods in Enzymology, 1984, 105, 114–120.

Hao X, Wang H, Cui F, Yang Z, Ye L, Huang R, et al. Reduction of SLC7A11 and GPX4 contributing to ferroptosis in sperm from asthenozoospermia individuals. Reproductive Sciences, 2023, 30(1), 247–257.

Imai H, Nakagawa Y. Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radical Biology & Medicine, 2003, 34(2), 145–169.

Li L, Jin T, Chen S, Cao H, Ma Y, Fang W, et al. Exploring novel function of Gpx5 antioxidant activity: Assisting epididymal cells secrete functional extracellular vesicles. Journal of Cellular Physiology, 2024, 239(6), e31273.

Liu A, Li F, Xu P, Chen Y, Liang X, Zheng S, et al. Gpx4, Selenov, and Txnrd3 are the most testis-abundant selenogenes resistant to dietary selenium and expressed during reproductive ages in rats. Biological Trace Element Research, 2023, 201(1), 250–259.

Mruk DD, Cheng CY. Sertoli–Sertoli and Sertoli–germ cell interactions and their significance in germ cell movement in the seminiferous epithelium. Endocrine Reviews, 2004, 25(5), 747–806.

Murakoshi M, Osamura Y, Yoshimura S, Watanabe K. Immunohisto-cytochemical localization of glutathione peroxidase in the rat testis. Acta Histochemica et Cytochemica, 1983, 16(4), 335–345.

Nguyen T, Sherratt PJ, Pickett CB. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annual Review of Pharmacology and Toxicology, 2003, 43, 233–260.

Puglisi R, Maccari I, Pipolo S, Conrad M, Mangia F, Boitani C. Nuclear glutathione peroxidase 4 and its role in sperm chromatin decondensation at fertilization. Journal of Cellular Physiology, 2012, 227(4), 1420–1427.

Qazi IH, Angel C, Yang H, Zoidis E, Pan B, Wu Z, et al. Role of selenium and selenoproteins in male reproductive function: A review. Antioxidants, 2019, 8(8), 268.

Schneider M, Forster H, Boersma A, Seiler A, Wehnes H, Sinowatz F, et al. Mitochondrial glutathione peroxidase 4 disruption causes male infertility. FASEB Journal, 2009, 23(9), 3233–3242.

Tsao CW, Liao YR, Chang TC, Liew YF, Liu CY. Effects of iron supplementation on testicular function and spermatogenesis in iron-deficient rats. Nutrients, 2022, 14(10), 2063.

Tvrda E, Kňažická Z, Bardos L, Massányi P, Lukáč N. Impact of oxidative stress on male fertility: A review. Acta Veterinaria Hungarica, 2011, 59(4), 465–484.

Ursini F, Heim S, Kiess M, Maiorino M, Roveri A, Wissing J, Flohé L. Dual function of the selenoprotein PHGPx during sperm maturation. Science, 1999, 285(5432), 1393–1396.

Wilkinson SR, Meyer DJ, Kelly JM. Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity. Biochemical Journal, 2000, 352(3), 755–761.

Zhang Y, Roh YJ, Han SJ, Park I, Lee HM, Ok YS, et al. Role of selenoproteins in redox regulation of signaling and the antioxidant system: A review. Antioxidants, 2020, 9(5), 383.

Zhaojin L, Yongchao Z, Huizi S, Jiaxin Z. Antioxidant function of GPX5 gene in epididymis of sheep. Journal of Northwest A & F University – Natural Science Edition, 2022, 50(8).