Sepsis Ve Yönetimi

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Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock. JAMA. 2016 Feb 23. 315 (8):775-87.

Shankar-Hari M, Philips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, et al. Developing a New Definition and Assesing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock. JAMA. 2016 Feb 23. 315 (8):775-87.

Merrell RC. The Abdomen as Source of Sepsis in Critically Ill Patients. Crit Care Clin. 1995 Apr. 11(2):255-72.

Marik PE. Fever in the ICU. Chest. 2000 Mar. 117(3):855-69.

Vincent JL, Rello J, Marshall J, et al. International Study of the Prevalence and Outcomes of Infection in Intensive Care Units. JAMA 2009;302:2323-9.

Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of Severe Sepsis in the United States: Analysis of Incidence, Outcome, and Associated Costs of Care. Crit Care Med 2001;1303-10.

Harrison DA, Welch CA, Eddleston JM. The Epidemiology of Severe Sepsis in England, Wales and Northern Ireland, 1996 to 2004. Crit Care Med 2006;10:R42.

Adrie C, Azoulay E, Francais A, et al. Influence of Gender on the Outcome of Severe Sepsis: A Reappraisal. Chest 2007;132:1786-93.

Martin GS, Mannino DM, Eaton S, Moss M. The Epidemiology of Sepsis in the United States from 1979 through 2000. N Engl J Med 2003;348:1546-54.

O’Brien JM, Lu B, Ali NA, et al. Alcohol Dependence is Independently Associated with Sepsis, Septic Shock, and Hospital Mortality Among Adult Intensive Care Unit Patients. Crit Care Med 2007;35:345-50.

De Haan K, Groeneveld AB, De Geus HR, Egal M, Struijs A. Vitamin D Deficiency as a Risk Factor for Infection, Sepsis and Mortality in the Critically Ill: Systematic Review and Meta-analysis. Crit Care 2014;18:660.

Williams MD, Braun LA, Cooper LM, et al. Hospitalized Cancer Patients with Severe Sepsis: Analysis of Incidence, Mortality, and Associated Costs of Care. Crit Care 2004;8:R291-8

Agnese DM, Calvano JE, Hahm SJ, et al. Human Toll-like Receptor 4 Mutations but not CD14 Polymorphisms are Associated with an Increased Risk of Gram-negative Infections. J Infect Dis 2002;186:1522-5

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Thiery-Antier N, Binquet C, Vinault S, Meziani F, Boisrame-Helms J, et al. Is Thrombocytopenia an Early Prognostic Marker in Septic Shock? Crit Care Med 2016 Apr. 44(4):764-72

Jeffrey EG, Michael AM. Sepsis: Pathophysiologhy and Clinical Management BMJ 2016;353:i1585

Amber MB. Bacterial Sepsis. Medscape 2019 Feb.

Aird WC. The Role of the Endothelium in Severe Sepsis and Multiple Organ Dysfunction Syndrome. Blood 2003;101:3765-77

Levi M. Pathogenesis and Treatment of Disseminated Intravascular Coagulation in the Septic Patient. J Crit Care 2001;16:167-77.

Parker MM, Shelhamer JH, Bacharach SL, et al. Profound but Reversible Myocardial Deression in Patients with Septic Shock. Ann Intern Med 1984;100:483-90

Wiedemann HP, Wheeler AP, Bernard GR, et al. National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Comparison of Two Fluid-management Strategies in Acute Lung Injury. N Engl J Med 2006;354:2564-75

Prowle JR, Bellomo R. Sepsis-associated Acute Kidney Injury: Macrohemodynamic and Microhemodynamic Alterations in the Renal Circulation. Semin Nephrol 2015;35:64-74

Iacobone E, Bailly-Salin J, Polito A, Friedman D, Stevens RD, Sharshar T. Sepsis-associated Encephalopathy and Its Differential Diagnosis. Crit Care Med 2009;37 (Suppl):S331-6.

Kumar A, Roberts D, Wood KE, et al. Duration of Hypotension Before Initiation of Effective Antimicrobial Therapy is the Critical Determinant of Survival in Human Septic Shock. Crit Care Med 2006;34:1589-96.

Savage RD, Fowler RA, Rishu AH, Bagshaw SM, et al. Pathogens and Antimicrobial Susceptibility Profiles in Critically Ill Patients with Bloodstream Infections: A Descriptive Study. CMAJ 2016;4(4):E569.

Gregory AS, Jess M. Evaluation and Management of Suspected Sepsis and Septic Shock in Adults. Uptodate October 2019

Damian McNamara. Severe Sepsis Strategy Significantly reduces Mortality. American College of Emergency Physicians Scientific Assembly. October 2013.

Rivers E, Nguyen B, Havstad S, et al. Early Goal-Directed Therapy Collaborative Group. Early Goal-directed Therapy in the Treatment of Severe Sepsis and Septic Shock. N Engl J Med 2001;345:1368-77.

De Backer D, Aldecoa C, Njimi H, Vincent JL. Dopamine versus Norepinephrine in the Treatment of Septic Shock: A Metaanalysis. Crit Care Med 2012;40:725-30

Nguyen HB, Lu S, Possagnoli I, Stokes P. Comparative Effectiveness of Second Vasoactive Agents in Septic Shock Refractory to Norepinephrine. J Intensive Care Med 2017;32(7):451

Eisner MD, Thompson T, Hudson LD, et al. Acute Respiratory Distress Syndrome Network. Efficacy of Low tidal Volume Ventilation in Patients with Different Clinical Risk Factors for Acute Lung Injury and the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 2001;164:231-6

Finfer S, Chittock DR, Su SY, et al. Intensive versus Conventional Glucose Control in Critically Ill Patients. N Engl J Med 2009;360:1283-97

Winters BD, Eberlein M, Leung J, Needham DM, et al. Long-term Mortality and Quality of Life in Sepsis: A Systematic Review Crit Care Med 2010 May. 38(5):1276-83