Hiperandrojenizm-İnsülin Rezistansı-Akantosis Nigrikans (Haır-An) Sendromu: Bir Olgu Sunumu
Özet
On dokuz yaşında kadın hasta, progresif hirsutizm, oligomenore ve akantosis nigrikans bulgularıyla başvurdu. Laboratuvar incelemelerinde ciddi insülin direnci (HOMA-IR: 7.0), hiperinsülinemi (29.7 µU/mL) ve hiperandrojenemi (total testosteron: 0.805 ng/mL) saptandı. HAIR-AN sendromu tanısıyla yaşam tarzı modifikasyonları, metformin ve oral kontraseptif kombinasyonu başlandı. Üç ay sonunda HOMA-IR değeri 3.10'a, insülin düzeyi 14.7 µU/mL'ye geriledi. Olgu, HAIR-AN sendromunun erken tanı ve multidisipliner tedavi yaklaşımının önemini vurgulamaktadır.
Referanslar
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