Meme Kanseri ile İlişkili Dermatomiyozit Olgusu
Özet
Paraneoplastik olarak gelişen dermatomiyozit hastalığı, maligniteler ile ilişkili gelişen otoimmün bir miyopati olarak bilinmektedir. Bu yazıda eş zamanlı olarak dermatomiyozit ve meme kanseri tanısı konulan bir vaka sunulmuştur. Tipik cilt bulguları ve kas gücü kaybı ile başvuran hastada fizik muayenede aksiller LAP saptanmış olup ultrasonografik olarak malign özellik göstermesi üzerine yapılan ileri incelemeler ile hastada meme invaziv ductal adenokarsinom saptandı. Hastanın dermatomiyozite yönelik yapılan tetkiklerinde anti NXP2 antikoru pozitif, EMG’de miyojen tutulum, kas biyopsisinde ise inflamatuvar miyozit bulguları görüldü. Hastaya steroid tedavisi başlanıp, ardından modifiye redikal mestektomi ve adjuvant KT ve RT uygulandı. Hastada cilt ve kas semptomları geriledi. Hasta halen remisyonda takip edilmektedir. Dermatomiyozit saptanan hastada olası malign süreçler mutlaka akılda tutulmalı ve bu hastaların takibi titizlikle yapılmalıdır.
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