Deri, Yumuşak Doku ve Göz Enfeksiyonlarında Güncel Tanı Yaklaşımları

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Guo B, Bai Y, Qin N, Li Y, Rong R, Luo L, Zhang Y, Wang R. Dermoscopy-guided sampling improves the diagnostic yield of fungal culture for onychomycosis: a comparative study. Front Med (Lausanne). 2026;13:1703199. doi:10.3389/fmed.2025.1703199

Blumenthal SR, Cheema AN, Zhang SE, Gray BL, Kazmers NH. Evaluating the utility of inflammatory markers in the diagnosis of soft tissue abscesses of the forearm and hand. J Bone Joint Infect. 2023;8(2):119-123. doi:10.5194/jbji-8-119-2023

Taniguchi T, Tsuha S, Shiiki S, Narita M, Teruya M, Hachiman T, Kogachi N. High yield of blood cultures in the etiologic diagnosis of cellulitis, erysipelas, and cutaneous abscess in elderly patients. Open Forum Infect Dis. 2022;9(7):ofac317. doi:10.1093/ofid/ofac317

Österhed E, Oldberg K, Gustafsson I. Aetiology and antibiotic susceptibility of bacterial keratitis at a referral centre in southern Sweden. Sci Rep. 2025;15(1):20123. doi:10.1038/s41598-025-04404-7

Monteiro AY, Cheng HM, Lim L, Pan JY, Liang K, Tey HL. A prospective cohort study comparing microscopy and culture in the diagnosis of superficial fungal skin infections. Med Sci (Basel). 2025;13(4):247. doi:10.3390/medsci13040247

Dehghani M, Norouzi H, Dehghan S, Spruill ML, Goodarzi M, Lee KH, Martin HL. Comparative diagnostic evaluation of real-time PCR and culture for detecting pathogens in podiatric wound infections. Microbiol Spectr. 2026;14:e02649-25. doi:10.1128/spectrum.02649-25

Bohjanen S, Goldstick C, Hordinsky M. Testing for methicillin-resistant Staphylococcus aureus in the anterior nares for antibiotic de-escalation in patients presenting with acute skin and soft tissue infections: systematic review and meta-analysis. Infect Control Hosp Epidemiol. 2025;46(7):1-5. doi:10.1017/ice.2025.58

Park S, Kim K, Lee Y, Ryoo N. Enhanced detection of bacterial ocular pathogens: a comparative study of broad-range real-time PCR and conventional culture methods. Diagnostics (Basel). 2025;15(8):966. doi:10.3390/diagnostics15080966

Gupta AK, Cooper EA, Wang T, Lincoln SA, Bakotic WL. Single-point nail sampling to diagnose onychomycosis caused by non-dermatophyte molds: utility of polymerase chain reaction (PCR) and histopathology. J Fungi (Basel). 2023;9(6):671. doi:10.3390/jof9060671

Kam KYR, Ong HS, Bunce C, Ogunbowale L, Verma S. Sensitivity and specificity of the AdenoPlus point-of-care system in detecting adenovirus in conjunctivitis patients at an ophthalmic emergency department: a diagnostic accuracy study. Br J Ophthalmol. 2015;99(9):1186-1189. doi:10.1136/bjophthalmol-2014-306508

Johnson SD, Harthan JS, Than T, Migneco MK, Shorter E, Whiteside MM, Morettin CE, Olson CK, Rosemann CA, Margolis MS, Haertter LW, Huecker JB, Rodic-Polic B, Buller RS, Storch GA, Gordon MO, Hartwick ATE. Predictive accuracy and densitometric analysis of point-of-care immunoassay for adenoviral conjunctivitis. Transl Vis Sci Technol. 2021;10(9):30. doi:10.1167/tvst.10.9.30

Close RM, Sutcliffe CG, Galdun P, Reid A, Askew MR, Davidson AM, Kellywood K, Parker D, Patel J, Romancito E, Brown LB, McAuley JB, Hammitt LL. Point-of-care molecular diagnostics for the detection of group A Streptococcus in non-invasive skin and soft tissue infections: a validation study. Diagn Microbiol Infect Dis. 2022;103(4):115729. doi:10.1016/j.diagmicrobio.2022.115729

Wu R, Li M, Du W, Chen Z, Yin S, Hu L, Xi L, Zhang J, Huang H. Rapid detection of fungi in nail specimens using multi-tube recombinase polymerase amplification assay. Mycoses. 2026;69(2):e70162. doi:10.1111/myc.70162

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Subramaniam S, Bober J, Chao J, Zehtabchi S. Point-of-care ultrasound for diagnosis of abscess in skin and soft tissue infections. Acad Emerg Med. 2016;23(11):1298-1306. doi:10.1111/acem.13049

Lam K, van Asten SAV, Nguyen T, La Fontaine J, Lavery LA. Diagnostic accuracy of probe to bone to detect osteomyelitis in the diabetic foot: a systematic review. Clin Infect Dis. 2016;63(7):944-948. doi:10.1093/cid/ciw445

Ulusoy S, Kılınç İ, Coşkun B, Ayhan M. Are deep tissue cultures a reliable alternative to bone biopsy for diagnosing diabetic foot osteomyelitis? A comparative diagnostic study. Diagnostics (Basel). 2025;15(7):880. doi:10.3390/diagnostics15070880

Chen IC, Li WC, Hong YC, Shie SS, Fann WC, Hsiao CT. The microbiological profile and presence of bloodstream infection influence mortality rates in necrotizing fasciitis. Crit Care. 2011;15(3):R152. doi:10.1186/cc10278

Tanaka T, Ferreira BFA, Oliveira LMS, Kato JM, Di Gioia TSR, Rossi F, Nakashima Y, Pimentel SLG, Yamamoto JH, de Almeida Junior JN. Diagnostic value of pediatric blood culture bottles for acute postoperative endophthalmitis. Clinics (Sao Paulo). 2019;74:e837. doi:10.6061/clinics/2019/e837

Sjoholm-Gomez de Liano C, Soberon-Ventura VF, Salcedo-Villanueva G, et al. Sensitivity, specificity and predictive values of anterior chamber tap in cases of bacterial endophthalmitis. Eye Vis (Lond). 2017;4:16. doi:10.1186/s40662-017-0083-9

Chidambaram JD, Prajna NV, Larke NL, Palepu S, Lanjewar S, Shah M, Elakkiya S, Lalitha P, Carnt N, Vesaluoma MH, Mason M, Hau S, Burton MJ. Prospective study of the diagnostic accuracy of the in vivo laser scanning confocal microscope for severe microbial keratitis. Ophthalmology. 2016;123(11):2285-2293. doi:10.1016/j.ophtha.2016.07.009

Hau SC, Dart JKG, Vesaluoma M, Parmar DN, Claerhout I, Larkin DFP. Diagnostic accuracy of microbial keratitis with in vivo scanning laser confocal microscopy. Br J Ophthalmol. 2010;94(8):982-987. doi.org/10.1136/bjo.2009.175083

Hoffman JJ, Dart JKG, De SK, Carnt N, Cleary G, Hau S. Comparison of culture, confocal microscopy and PCR in routine hospital use for microbial keratitis diagnosis. Eye (Lond). 2022;36(11):2172-2178. doi:10.1038/s41433-021-01812-7

Shankarnarayan SA, Shaw D, Sharma A, Chakrabarti A, Dogra S, Kumaran MS, Kaur H, Ghosh A, Rudramurthy SM. Rapid detection of terbinafine resistance in Trichophyton species by amplified refractory mutation system-polymerase chain reaction. Sci Rep. 2020;10:1297. doi:10.1038/s41598-020-58187-0

Wolk DM, Struelens MJ, Pancholi P, Davis T, Della-Latta P, Fuller D, Picton E, Dickenson R, Denis O, Johnson D, Chapin K. Rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in wound specimens and blood cultures: multicenter preclinical evaluation of the Cepheid Xpert MRSA/SA skin and soft tissue and blood culture assays. J Clin Microbiol. 2009;47(3):823-826. doi:10.1128/JCM.01884-08

Shi Q, Mao D, Zhang Z, Qudsi AI, Wei M, Cheng Z, Zhang Y, Wang Z, Chen K, Xu X, Lu X, Liang Q. Epidemiological and antimicrobial resistance trends in bacterial keratitis: a hospital-based 10-year study (2014-2024). Microorganisms. 2025;13(3):670. doi:10.3390/microorganisms13030670

Xie H, Chen Z, Wu G, Wei P, Gong T, Chen S, Xu Z. Application of metagenomic next-generation sequencing (mNGS) to describe the microbial characteristics of diabetic foot ulcers at a tertiary medical center in South China. BMC Endocr Disord. 2025;25:18. doi:10.1186/s12902-025-01837-z

Zhang X, Li W, Wu H, Cai T, Chen H, Zeng S. Enhanced pathogen identification in fungal endophthalmitis by metagenomic next-generation sequencing: a retrospective clinical evaluation. Sci Rep. 2026;16:18834. doi:10.1038/s41598-026-50225-7

Rhodes J, Hui ST, Dellière S, Summerbell RC, Scott JA, Kaur A, Barton RC, Leitao R, Hemmings S, Goiriz R, Lambourne J, Farrer RA, Schelenz S, Hay RJ, Borman AM, Chowdhary A, Abdolrasouli A, Fisher MC. Emerging terbinafine-resistant Trichophyton indotineae between 2018 and 2023: a multinational genomic epidemiology study. Lancet Microbe. 2026;7:101273. doi:10.1016/j.lanmic.2025.101273

Tjiu JW, Lu CF. Equity and generalizability of artificial intelligence for skin-lesion diagnosis using clinical, dermoscopic, and smartphone images: a systematic review and meta-analysis. Medicina (Kaunas). 2025;61(12):2186. doi:10.3390/medicina61122186

Ong ZZ, Sadek Y, Qureshi R, Liu SH, Li T, Liu X, Takwoingi Y, Sounderajah V, Ashrafian H, Ting DSW, Mehta JS, Rauz S, Said DG, Dua HS, Burton MJ, Ting DSJ. Diagnostic performance of deep learning for infectious keratitis: a systematic review and meta-analysis. EClinicalMedicine. 2024;77:102887. doi:10.1016/j.eclinm.2024.102887

Han SS, Park GH, Lim W, Kim MS, Na JI, Park I, Chang SE. Deep neural networks show an equivalent and often superior performance to dermatologists in onychomycosis diagnosis: automatic construction of onychomycosis datasets by region-based convolutional deep neural network. PLoS One. 2018;13(1):e0191493. doi:10.1371/journal.pone.0191493

Goolden C, Shorten RJ. Diagnostic stewardship - optimization of superficial wound swab cultures can reduce the environmental impact of the microbiology laboratory. Access Microbiol. 2025;7(9):000977.v3. doi:10.1099/acmi.0.000977.v3

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Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan SL, Montoya JG, Wade JC. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59(2):147-159. doi:10.1093/cid/ciu296

Rhee MK, Ahmad S, Amescua G, Cheung AY, Choi DS, Jhanji V, Lin A, Mian SI, Viriya ET, Mah FS, Varu DM; American Academy of Ophthalmology Preferred Practice Pattern Cornea/External Disease Panel. Bacterial keratitis Preferred Practice Pattern®. Ophthalmology. 2024;131(4):P87-P133. doi:10.1016/j.ophtha.2023.12.035