DNA Replikasyonu

Yazarlar

Emin Özköse

Referanslar

Khan, I., Sommers, J. A., & Brosh, R. M. Close encounters for the first time: Helicase interactions with DNA damage. DNA Repair. 2015; 33, 43–59. https://doi.org/10.1016/j.dnarep.2015.06.003

Levin, B.. Genes V. Oxford University Press, Oxford / UK. 1994.

Pursell, ZF., Isoz, I., Lundström EB., et al.. Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science. 2007 Jul 6;317(5834):127-30. doi: 10.1126/science.1144067. PMID: 17615360; PMCID: PMC2233713.

Rossi R., Montecucco, A., Ciarrocchi, G et al. Functional characterization of the T4 DNA ligase: a new insight into the mechanism of action. Nucleic Acids Research, 1997, 25: 2106–2113, doi.org/10.1093/nar/25.11.2106.

Yang, W. An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η. Biochemistry. 2014. Doi: 10.1021/bi500019s 53: 2793–2803.

Swan, M., Johnson, R., Prakash, L. et al. Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ. Natural Structural Molecular Biology. 2009. 16, 979–986. https://doi.org/10.1038/nsmb.1663

Li, Y., Dang, N.K., He, W. et al. (2025). Pol θ-mediated end-joining uses microhomologies containing mismatches. Nature Communications. 2025 Jul 2;16(1):6085. doi: 10.1038/s41467-025-61258-3. PMID: 40603872; PMCID: PMC12222517. 16: 6085.

Gan, G., Wittschieben, J., Wittschieben, B. et al. DNA polymerase zeta (pol ζ) in higher eukaryotes. Cell Research. 2008. 18, 174–183 (008. doi: 10.1038/cr. 2007.117

Andrade, P., Martin, M.J., Juárez, R. et al. Limited terminal transferase in human DNA polymerase μ defines the required balance between accuracy and efficiency in NHEJ, Proceeding of the National Academic Science. U.S.A. 2009 Sep 22;106(38):16203-8. doi: 10.1073/pnas.0908492106.

Balakrishnan L and Bambara RA. Metabolism of Okazaki Fragments. Cold Spring Harbor Biology Perspectives. 2013. 5 (2) a010173. doi : 10.1101 /cshperspect. a010173. PMC 355508 . PMID 23378587

Engler, M.J and Richardson, C.C. DNA Ligases, in The Enzymes, Third Edition 1982. 15:3-29. https://doi.org/10.1016/S1874-6047(08)60273-5

Sayfalar

19-30

Yayınlanan

5 Ekim 2026

Lisans

Lisans