LAD KTO İle Birlikte D1 Lezyonunun Tek Seansta Yönetimi: KTO ve Bifurkasyon PKG Deneyimi
Özet
Kronik total oklüzyon (KTO) girişimleri, koroner perkütan koroner girişimlerin (PKG) teknik olarak en zorlu alt gruplarından birini oluşturur. Bu zorluk, oklüzyonun başladığı proksimal kapta önemli bir yan dalın bulunduğu bifurkasyon anatomilerinde belirgin biçimde artar. Bu bölümde, sol ön inen arter (LAD) proksimalinde diyagonal dalın çıkış yaptığı noktada yer alan bir KTO olgusu sunulmaktadır. Olguda önce diyagonal dal stentlenmiş, ardından oklüde segment mikrokateter ve özelleşmiş KTO kılavuz telleri ile geçilerek ana damar stentlenmiş ve bifurkasyon iki-stent tekniğiyle tamamlanmıştır. Olgu, güncel literatür ve kılavuz önerileri ışığında tartışılmaktadır.
Chronic total occlusion (CTO) interventions represent one of the most technically demanding subsets of percutaneous coronary intervention (PCI). This difficulty increases markedly in bifurcation anatomies in which a significant side branch is present at the proximal cap where the occlusion begins. In this chapter, a CTO case located at the point where the diagonal branch arises from the proximal left anterior descending artery (LAD) is presented. In this case, the diagonal branch was first stented; the occluded segment was then crossed using a microcatheter and dedicated CTO guidewires, the main vessel was stented, and the bifurcation was completed with a two-stent technique. The case is discussed in light of the current literature and guideline recommendations.
Referanslar
Zhang S, Hu G, Zhang B, et al. Successful true cavity pathfinding with balloon-assisted CTO with bifurcation lesions: two case reports. Medicine (Baltimore). 2024;103:e37404.
Xenogiannis I, Pavlidis AN, Kaier TE, et al. The role of intravascular imaging in chronic total occlusion percutaneous coronary intervention. Front Cardiovasc Med. 2023;10:1199067. doi:10.3389/fcvm.2023.1199067
Lefèvre T, Pan M, Stankovic G, et al. CTO and bifurcation lesions: an expert consensus from the European Bifurcation Club and EuroCTO Club. JACC Cardiovasc Interv. 2023;16(17):2065-2082. doi:10.1016/j.jcin.2023.06.042
Bujak K, Verardi FM, Arevalos V, et al. Clinical outcomes following different stenting techniques for coronary bifurcation lesions: a systematic review and network meta-analysis of randomised controlled trials. EuroIntervention. 2023;19(8):664-675. doi:10.4244/EIJ-D-23-00013
Arunothayaraj S, Hildick-Smith D, Stankovic G, et al. Stepwise provisional versus systematic dual-stent strategies for treatment of true left main coronary bifurcation lesions. Circulation. 2025;151(9):612-622. doi:10.1161/CIRCULATIONAHA.124.071153
Chen X, Li X, Zhang JJ, et al. 3-year outcomes of the DKCRUSH-V trial comparing DK crush with provisional stenting for left main bifurcation lesions. JACC Cardiovasc Interv. 2019;12(19):1927-1937. doi:10.1016/j.jcin.2019.04.056
Hong D, Kim Y, Lee JH, Lee SJ, et al. Current evidence for prognostic benefit of intravascular imaging-guided percutaneous coronary intervention in chronic total occlusion intervention. Korean J Intern Med. 2024;39:215-227.
Sliman H, Kasem Ali Sliman R, Knaapen P, Nap A, Sobieszek G, Opolski MP. The role of intravascular imaging in coronary chronic total occlusion PCI: enhancing procedural success through real-time visualization. J Pers Med. 2025;15(7):318. doi:10.3390/jpm15070318
Kim BK, Shin DH, Hong MK, et al. Clinical impact of intravascular ultrasound-guided chronic total occlusion intervention. Circ Cardiovasc Interv. 2015;8:e002592. doi:10.1161/CIRCINTERVENTIONS.115.002592
Holm NR, Andreasen LN, Neghabat O, et al. OCT or angiography guidance for PCI in complex bifurcation lesions. N Engl J Med. 2023;389(16):1477-1487. doi:10.1056/NEJMoa2307770
Truesdell AG, Alasnag MA, Kaul P, et al. Intravascular imaging during percutaneous coronary intervention: JACC state-of-the-art review. J Am Coll Cardiol. 2023;81(6):590-605. doi:10.1016/j.jacc.2022.11.045