Restoratif Diş Tedavisinde, Mine Remineralizasyonuna Güncel Yaklaşım

Machiulskiene V, Campus G, Carvalho JC, Dige I, Ekstrand KR, Jablonski-Momeni A, et al. Terminology of dental caries and dental caries management: Consensus report of a workshop organized by ORCA and Cariology Research Group of IADR. Caries Res. 2020;54:7-14.

Balhaddad AA, Kansara AA, Hidan D, Weir MD, Xu HHK, Melo MAS. Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials. Bioact Mater. 2019;4:43-55.

Al-Dulaijan YA, Balhaddad AA. Prospects on tuning bioactive and antimicrobial denture base resin materials: A narrative review. Polymers (Basel). 2022;15:54.

Finer Y, Santerre JP. Salivary esterase activity and its association with the biodegradation of dental composites. J Dent Res. 2004;83:22-26.

Zahra FT, Asghar M, Zafar MS, et al. Effectiveness of remineralizing dentifrices against caries lesions: A systematic approach. J Taibah Univ Med Sci. 2025.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Angelova Volponi A, Zaugg LK, Neves V, et al. Tooth repair and regeneration. Curr Oral Health Rep. 2018;5(4):295-303.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Khalil AM, Abbassy SA, Mohy ElDin MM, Kandil S, El-Khatib AM. A synergistic approach to tooth remineralization using nano-chitosan and fluoride. Sci Rep. 2025;15:16058.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Fernandes NLS, Silva JGVC, de Sousa EBG, D’Alpino PHP, de Oliveira AFB, de Jong E, Sampaio FC. Effectiveness of fluoride-containing toothpastes associated with different technologies to remineralize enamel after pH cycling. BMC Oral Health. 2022;22:429.

Amaechi BT, AbdulAzees PA, Okoye LO, Meyer F, Enax J. Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: A pH-cycling study. BDJ Open. 2020;6:9.

Khalil AM, Abbassy SA, Mohy ElDin MM, Kandil S, El-Khatib AM. A synergistic approach to tooth remineralization using nano-chitosan and fluoride. Sci Rep. 2025;15:16058.

Liang K, Xiao S, Shi W, Li J, Yang X, Gao Y, Li J. 8DSS-promoted remineralization of demineralized dentin in vitro. J Mater Chem B. 2015;3(33):6763-6772.

Zheng W, Ding L, Wang Y, Han S, Zheng S, Guo Q, et al. The effects of 8DSS peptide on remineralization in a rat model of enamel caries evaluated by two nondestructive techniques. J Appl Biomater Funct Mater. 2019;17(1).

Khalil AM, Abbassy SA, Mohy ElDin MM, Kandil S, El-Khatib AM. A synergistic approach to tooth remineralization using nano-chitosan and fluoride. Sci Rep. 2025;15:16058.

Dawasaz AA, Togoo RA, Mahmood Z, Azlina A, Ponnuraj KT. Effectiveness of self-assembling peptide (P11-4) in dental hard tissue conditions: A comprehensive review. Polymers (Basel). 2022;14(4):792.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Fan M, Zhang M, Xu HHK, Tao S, Yu Z, Yang J, Li J. Remineralization effectiveness of the PAMAM dendrimer with different terminal groups on artificial initial enamel caries in vitro. Dent Mater. 2020;36(2):210-220.

Sakr AH, Nassif MS, El-Korashy DI. Amelogenin-inspired peptide, calcium phosphate solution, fluoride and their synergistic effect on enamel biomimetic remineralization: An in vitro pH-cycling model. BMC Oral Health. 2024;24(1):279.

Sun M, Wu N, Chen H. Laser-assisted rapid mineralization of human tooth enamel. Sci Rep. 2017;7(1).

Bordea IR, Candrea S, Alexescu GT, Bran S, Baciut M, Baciut G, Todea DA. Nano-hydroxyapatite use in dentistry: A systematic review. Drug Metab Rev. 2020;1-14.

Pitts NB, Wright JP. Reminova and EAER: Keeping enamel whole through caries remineralization. Adv Dent Res. 2018;29(1):48-54.

Ruan Q, Moradian-Oldak J. Amelogenin and enamel biomimetics. J Mater Chem B. 2015;3(16):3112-3129.

Amaechi BT, AbdulAzees PA, Okoye LO, Meyer F, Enax J. Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: A pH-cycling study. BDJ Open. 2020;6:9.

Calcium phosphate-based remineralization systems: Scientific evidence and clinical relevance. J Dent. 2021;104:103528.

Dionysopoulos D, Gerasimidou O, Papageorgiou SN. Fluoride-enhancing and fluoride-free remineralization strategies: Current concepts and future perspectives. Dent Mater. 2022;38(7):e205-e222.

Xu HHK, Weir MD, Chow LC. Nanocomposite containing amorphous calcium phosphate nanoparticles for caries inhibition. Dent Mater. 2019;35(8):1211-1223.

Xu HHK, Weir MD, Sun L, et al. Effects of calcium phosphate nanoparticle size on Ca-PO4 ion release and dental resin mechanical properties. Dent Mater. 2011;27(10):1032-1043.

Xu HHK, Moreau JL, Sun L, Chow LC. Novel CaPO4 nanocomposite with high strength and remineralization potential.

Buzalaf MAR, Pessan JP, Honório HM, Ten Cate JM. Mechanisms of action of fluoride for caries control. Monogr Oral Sci. 2011;22:97-114.

Par M, Tarle Z, Hickel R, Ilie N. Mechanical properties, bioactivity and antibacterial effects of bioactive glass-containing dental composites: A review. Dent Mater. 2022;38(2):295-312.

Par M, Tarle Z, Hickel R, Ilie N. Bioactive dental composites: Functionalization with hydroxyapatite and fluorapatite fillers. Dent Mater. 2021;37(9):1345-1361.

Par M, Tarle Z, Hickel R, Ilie N. Bioactive fillers in restorative dental materials: Current status and future perspectives. Dent Mater. 2023;39(4):463-487.

Machiulskiene V, Campus G, Carvalho JC, Dige I, Ekstrand KR, Jablonski-Momeni A, et al. Terminology of dental caries and dental caries management: Consensus report of a workshop organized by ORCA and Cariology Research Group of IADR. Caries Res. 2020;54:7-14.

Balhaddad AA, Kansara AA, Hidan D, Weir MD, Xu HHK, Melo MAS. Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials. Bioact Mater. 2019;4:43-55.

Al-Dulaijan YA, Balhaddad AA. Prospects on tuning bioactive and antimicrobial denture base resin materials: A narrative review. Polymers (Basel). 2022;15:54.

Finer Y, Santerre JP. Salivary esterase activity and its association with the biodegradation of dental composites. J Dent Res. 2004;83:22-26.

Zahra FT, Asghar M, Zafar MS, et al. Effectiveness of remineralizing dentifrices against caries lesions: A systematic approach. J Taibah Univ Med Sci. 2025.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Angelova Volponi A, Zaugg LK, Neves V, et al. Tooth repair and regeneration. Curr Oral Health Rep. 2018;5(4):295-303.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Khalil AM, Abbassy SA, Mohy ElDin MM, Kandil S, El-Khatib AM. A synergistic approach to tooth remineralization using nano-chitosan and fluoride. Sci Rep. 2025;15:16058.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Fernandes NLS, Silva JGVC, de Sousa EBG, D’Alpino PHP, de Oliveira AFB, de Jong E, Sampaio FC. Effectiveness of fluoride-containing toothpastes associated with different technologies to remineralize enamel after pH cycling. BMC Oral Health. 2022;22:429.

Amaechi BT, AbdulAzees PA, Okoye LO, Meyer F, Enax J. Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: A pH-cycling study. BDJ Open. 2020;6:9.

Khalil AM, Abbassy SA, Mohy ElDin MM, Kandil S, El-Khatib AM. A synergistic approach to tooth remineralization using nano-chitosan and fluoride. Sci Rep. 2025;15:16058.

Liang K, Xiao S, Shi W, Li J, Yang X, Gao Y, Li J. 8DSS-promoted remineralization of demineralized dentin in vitro. J Mater Chem B. 2015;3(33):6763-6772.

Zheng W, Ding L, Wang Y, Han S, Zheng S, Guo Q, et al. The effects of 8DSS peptide on remineralization in a rat model of enamel caries evaluated by two nondestructive techniques. J Appl Biomater Funct Mater. 2019;17(1).

Khalil AM, Abbassy SA, Mohy ElDin MM, Kandil S, El-Khatib AM. A synergistic approach to tooth remineralization using nano-chitosan and fluoride. Sci Rep. 2025;15:16058.

Dawasaz AA, Togoo RA, Mahmood Z, Azlina A, Ponnuraj KT. Effectiveness of self-assembling peptide (P11-4) in dental hard tissue conditions: A comprehensive review. Polymers (Basel). 2022;14(4):792.

Ferizoli B, Cresswell-Boyes AJ, Anderson P, Lynch RJM, Hill RG. Effects of fluoride on in vitro hydroxyapatite demineralisation analysed by 19F MAS-NMR. Front Dent Med. 2023;4:1171827.

Fan M, Zhang M, Xu HHK, Tao S, Yu Z, Yang J, Li J. Remineralization effectiveness of the PAMAM dendrimer with different terminal groups on artificial initial enamel caries in vitro. Dent Mater. 2020;36(2):210-220.

Sakr AH, Nassif MS, El-Korashy DI. Amelogenin-inspired peptide, calcium phosphate solution, fluoride and their synergistic effect on enamel biomimetic remineralization: An in vitro pH-cycling model. BMC Oral Health. 2024;24(1):279.

Sun M, Wu N, Chen H. Laser-assisted rapid mineralization of human tooth enamel. Sci Rep. 2017;7(1).

Bordea IR, Candrea S, Alexescu GT, Bran S, Baciut M, Baciut G, Todea DA. Nano-hydroxyapatite use in dentistry: A systematic review. Drug Metab Rev. 2020;1-14.

Pitts NB, Wright JP. Reminova and EAER: Keeping enamel whole through caries remineralization. Adv Dent Res. 2018;29(1):48-54.

Ruan Q, Moradian-Oldak J. Amelogenin and enamel biomimetics. J Mater Chem B. 2015;3(16):3112-3129.

Amaechi BT, AbdulAzees PA, Okoye LO, Meyer F, Enax J. Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: A pH-cycling study. BDJ Open. 2020;6:9.

Calcium phosphate-based remineralization systems: Scientific evidence and clinical relevance. J Dent. 2021;104:103528.

Dionysopoulos D, Gerasimidou O, Papageorgiou SN. Fluoride-enhancing and fluoride-free remineralization strategies: Current concepts and future perspectives. Dent Mater. 2022;38(7):e205-e222.

Xu HHK, Weir MD, Chow LC. Nanocomposite containing amorphous calcium phosphate nanoparticles for caries inhibition. Dent Mater. 2019;35(8):1211-1223.

Xu HHK, Weir MD, Sun L, et al. Effects of calcium phosphate nanoparticle size on Ca-PO4 ion release and dental resin mechanical properties. Dent Mater. 2011;27(10):1032-1043.

Xu HHK, Moreau JL, Sun L, Chow LC. Novel CaPO4 nanocomposite with high strength and remineralization potential.

Buzalaf MAR, Pessan JP, Honório HM, Ten Cate JM. Mechanisms of action of fluoride for caries control. Monogr Oral Sci. 2011;22:97-114.

Par M, Tarle Z, Hickel R, Ilie N. Mechanical properties, bioactivity and antibacterial effects of bioactive glass-containing dental composites: A review. Dent Mater. 2022;38(2):295-312.

Par M, Tarle Z, Hickel R, Ilie N. Bioactive dental composites: Functionalization with hydroxyapatite and fluorapatite fillers. Dent Mater. 2021;37(9):1345-1361.

Par M, Tarle Z, Hickel R, Ilie N. Bioactive fillers in restorative dental materials: Current status and future perspectives. Dent Mater. 2023;39(4):463-487.