Papaver Rhoeas Zehirlenmesi: Yoğun Bakım Takibi Olgu Sunumu
Özet
Zehirlenmeler, acil ve yoğun bakım ünitelerinde sıkça karşılaşılan ve morbidite ile mortalite riski taşıyan önemli klinik durumlardır. Bu olgu sunumunda, oral yoldan Papaver rhoeas (gelincik) bitkisi tüketimi sonrası gelişen hafif nörolojik semptomlarla yoğun bakım ünitesine kabul edilen 65 yaşındaki bir kadın hasta ele alınmaktadır. Hastanın acil servise bilinç durum değişikliği ve somnolans tablosuyla başvurusu, opioid intoksikasyonu şüphesi uyandırmıştır. Yoğun bakımda uygulanan destekleyici tedavi ve yakın takip sonucunda hasta herhangi bir komplikasyon olmaksızın tamamen iyileşmiş ve taburcu edilmiştir.
Referanslar
Singh B, Unnikrishnan B. A profile of acute poisoning at Mangalore (South India). J Clin Forensic Med. 2006 Apr;13(3):112–6.
Mowry JB, Spyker DA, Brooks DE, Zimmerman A, Schauben JL. 2015 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 33rd Annual Report. Clin Toxicol (Phila). 2016 Dec;54(10):924–1109.
Deng JF. Clinical and laboratory investigations in herbal poisonings. Toxicology. 2002 Dec 27;181–182:571–6.
Bol O. BİTKİLERLE ZEHİRLENMELER. asujms. 2020 Jun 15;1(özel sayı):63–5.
Saraç H, Daştan T, Durukan H, Durna S, Demi̇Rbaş A, Karaköy T. Kırmızı Gelincik (Fam: Papaveraceae, Glaucium grandiflorum Boiss.&Huet var. grandiflorum) Bitkisinin Farklı Özütlerinin Besin Elementi İçeriğinin ve In Vitro Antiproliferatif Etkilerinin Değerlendirilmesi.
Soulimani R, Younos C, Jarmouni-Idrissi S, Bousta D, Khallouki F, Laila A. Behavioral and pharmaco-toxicological study of Papaver rhoeas L. in mice. J Ethnopharmacol. 2001 Mar 3;74(3):265–74.
Çoban İ, Toplan GG, Özbek B, Gürer ÇU, Sarıyar G. Variation of alkaloid contents and antimicrobial activities of Papaver rhoeas L. growing in Turkey and northern Cyprus. Pharmaceutical Biology. 2017 Jan 1;55(1):1894–8.
Şimşek SD, Zortuk Ö, Dönmez FA, Bağdad S, Polat M, Şimşek SD, et al. Case Report: Anti-Cholinergic Syndrome Induced by Papaver Rhoeas Plant and Its Management. Global Emergency And Critical Care [Internet]. 2025 Apr 30 [cited 2025 Aug 31]; Available from: https://globemcc.com/articles/case-report-anti-cholinergic-syndrome-induced-by-papaver-rhoeas-plant-and-its-management/globecc.galenos.2024.52296
Saeed-Abadi S, Ranjbaran M, Jafari F, Najafi-Abedi A, Rahmani B, Esfandiari B, et al. Effects of Papaver rhoeas (L.) extract on formalin-induced pain and inflammation in mice. Pak J Biol Sci. 2012 Nov 1;15(21):1041–4.
Marsoul A, Ijjaali M, Oumous I, Bennani B, Boukir A. Determination of polyphenol contents in Papaver rhoeas L. flowers extracts (soxhlet, maceration), antioxidant and antibacterial evaluation. Materials Today: Proceedings. 2020 Jan 1;31:S183–9.
Kalav YN, Sariyar G. Alkaloids from Turkish Papaver rhoeas. Planta Medica. 2007 Jan 24;55:488–488.
Matysik G, Benesz M. Thin-layer chromatography and densitometry of anthocyanins in the petals of red poppy during development of the flowers. Chromatographia. 1991 Jul 1;32(1):19–22.
Polat M, Oztas P, Yalcin B, Tamer E, Gur G, Alli N. Contact dermatitis due to Allivum sativum and Ranunculus illyricus: two cases. Contact Dermatitis. 2007 Oct;57(4):279–80.
Pourmotabbed A, Rostamian B, Manouchehri G, Pirzadeh-Jahromi G, Sahraei H, Ghoshooni H, et al. Effects of Papaver rhoeas extract on the expression and development of morphine-dependence in mice. J Ethnopharmacol. 2004 Dec;95(2–3):431–5.
Zoofaghari S, Maghami-Mehr A, Abdolrazaghnejad A. Organophosphate Poisoning: Review of Prognosis and Management. Adv Biomed Res. 2024;13:82.
Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Rivers LJ, Feldman R, et al. 2021 Annual Report of the National Poison Data System© (NPDS) from America’s Poison Centers: 39th Annual Report. Clin Toxicol (Phila). 2022 Dec;60(12):1381–643.
Günaydın YK, Dündar ZD, Çekmen B, Akıllı NB, Köylü R, Cander B. Intoxication due to Papaver rhoeas (Corn Poppy): Five Case Reports. Case Rep Med. 2015;2015:321360.
Koçak S, Karabulut K, Ertekin B, Nak H, Cander B, Koçak S, et al. Red Poppy (Papaver Rhoeas) Poisoning: A Report of Three Cases. Cyprus Journal of Medical Sciences [Internet]. [cited 2025 Aug 31]; Available from: https://cyprusjmedsci.com/articles/red-poppy-papaver-rhoeas-poisoning-a-report-of-three-cases/cjms.2016.25
Gonullu H, Karadas S, Dulger AC, Ebinc S. Hepatotoxicity associated with the ingestion of Papaver Rhoease. J Pak Med Assoc. 2014 Oct;64(10):1189–90.
