Oral Cerrahide Prf Kullanımı ve Etkileri

Özet

Referanslar

Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol. 2009 Mar;27(3):158-67. doi: 10.1016/j.tibtech.2008.11.009. Epub 2009 Jan 31. PMID: 19187989.

Rumbaut RE, Thiagarajan P. San Rafael (CA): Morgan & Claypool Yaşam Bilimleri; 2010

Caymaz, M. G., & Uyanık, L. O. (2022). TROMBOSİTTEN ZENGİN ÜRÜNLER VE DİŞ HEKİMLİĞİNDEKİ UYGULANMA ALANLARI. Health Academy Kastamonu, 7(1), 143-164. https://doi.org/10.25279/sak.541936

Zornitsa Mihaylova, Vanyo Mitev, Pavel Stanimirov, Antonia Isaeva, Natalia Gateva & Nikolay Ishkitiev (2016): Use of platelet concentrates in oral and maxillofacial surgery: an overview, Acta Odontologica Scandinavica, DOI: 10.1080/00016357.2016.1236985

Pereira VBS, Lago CAP, Almeida RAC, Barbirato DDS, Vasconcelos BCDE. Biological and Cellular Properties of Advanced Platelet-Rich Fibrin (A-PRF) Compared to Other Platelet Concentrates: Systematic Review and Meta-Analysis. Int J Mol Sci. 2023 Dec 29;25(1):482. doi: 10.3390/ijms25010482. PMID: 38203653; PMCID: PMC10779223.

Plachokova AS, Nikolidakis D, Mulder J, Jansen JA, Creugers, NHJ. Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review. Clin. Oral Impl. Res. 19, 2008; 539–545 doi: 10.1111/j.1600-0501.2008.01525.x

Özdemir, B., & Ökte, E. (2010). Trombositten zengin plazmanın kemik içi periodontal defektlerin tedavisinde beta-trikalsiyum fosfat ile birlikte uygulanması. Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi, 27(1), 1-9.

J. V. d. S. Canellas, P. J. D. Medeiros, C. M. d. S. Figueredo, R. G. Fischer, F. G. Ritto: Platelet-rich fibrin in oral surgical procedures: a systematic review and meta-analysis. Int. J. Oral Maxillofac. Surg. 2018; xxx: xxx–xxx. ã 2018 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. https://doi.org/10.1016/j.ijom.2018.07.007

Clinical Uses of Platelet-Rich Fibrin in Oral and Maxillofacial Surgery Yijao Fan, DDSa, Karla Perez, DDSa, Harry Dym, DDSb,* Dent Clin N Am 64 (2020) 291–303 https://doi.org/10.1016/j.cden.2019.12.012

Dohan Ehrenfest DM, De Peppo GM, Doglioli P, et al. Slow release of growth factors and thrombospondin-1 in Choukroun’s platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies. Growth Factors. 2009;27:63–69

Kobayashi M, Kawase T, Horimizu, et al. A proposed protocol for the standardized preparation of PRF membranes for clinical use. Biologicals. 2012;40:323–329

Balcı, H. & Toker, H. (2012). Trombositten Zengin Fibrin: Özellikleri ve Diş Hekimliğinde kullanımı. Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi, 29(3), 183-192.

Chmielewski,M.;Pilloni, A.; Adamska,P.AdvancedPlateletRich Fibrin Plus (A-PRF+)asan Additive toHardTissueManaging Protocols in Oral Surgery: A Systematic Review. J. Funct. Biomater. 2025, 16, 145. https://doi.org/ 10.3390/jfb16040145

Fujioka-Kobayashi, M., Miron, R. J., Hernandez, M., Kandalam, U., Zhang, Y. & Choukroun, J. (2016). Optimized platelet rich fibrin with the low speed concept: Growth factor release, biocompatibility and celluler response. Journal of Periadontology, 88(1), 112-121

Chen, T.L., Lu, H.J., Liu, G.Q., Tang, D.H., Zhang, X.H., Pan, Z.L., Wang, S.F. & Zhang Q.F. (2014). Effect of autologous platelet-rich plasma in combination with bovine porous bone mineral and bio-guide membrane on bone regeneration in mandible bicortical bony defects. J Craniofac Surg., 25(1), 215-223.

O’Connell, S.M. (2007). Safety issues associated with platelet-rich fibrin method. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 103(5), 587-593.

Miron RJ, Fujioka-Kobayashi M, Hernandez M, Kandalam U, Zhang Y, Ghanaati S, Choukroun J. Injectable platelet rich fibrin (i-PRF): opportunities in regenerative dentistry? Clin Oral Investig. 2017 Nov;21(8):2619-2627. doi: 10.1007/s00784-017-2063-9. Epub 2017 Feb 2. PMID: 28154995.

Choukroun, J., Aalam, A.A. & Miron, R.J. (2017). Platelet rich fibrin “PRF” and regenerative medicine: ‘The low-speed concept’. MSCs and Innovative Biomaterials in Dentistry, Stem Cell Biology and Regenerative Medicine, 21-42.

Use of Platelet-Rich Plasma and Platelet- Rich Fibrin in Dentistry and Oral Surgery: Introduction and Review of the Literature Kristina Feigin, DVM, Dipl. AVDC1 and Bonnie

Shope, VMD, Dipl. AVDC Journal of Veterinary Dentistry 2019, Vol. 36(2) 109-123 ª The Author(s) 2019 Article reuse guidelines: sagepub.com/journals-permissions DOI: 10.1177/0898756419876057 journals.sagepub.com/home/jov

Gupta V, Bains K, Singh G, Mathur A, Baines R. Regenerative potential of platelet-rich fibrin in dentistry: literature review. Asian J Oral Health Allied Sci. 2011;1(1):22-28.

Wu C, Lee S, Tsai C, Lu K, Zhao J, Chang Y. Platelet-rich fibrin increases cell attachment, proliferation and collagen-related protein expression of human osteoblasts. Aust Dent J. 2012;57(2): 207-212.

Xu, L., Ding, Y., Lei, C. & Jiang, W. (2014). The Use of advance Platelet-Rich Fibrin during Immediate Implantation for the Esthetic Replacement of Maxillary Anterior Segment with Chronic Apical Lesion. International Journal of Science and Research (IJSR), 3(9), 1368-1372

Pathak, H., Mohanty, S., Urs, A.B. & Dabas, J. (2015). Treatment of oral mucosal lesions by scalpel excision and platelet-rich fibrin membrane grafting: a review of 26 sites. J Oral Maxillofac Surg, 73(9), 1865-1874

Ajwani, H., Shetty, S., Gopalakrishnan, D., Kathariya, R., Kulloli, A., Dolas, R.S. & Pradeep, A.R. (2015). Comparative evaluation of platelet-rich fibrin biomaterial and open flap debridement in the treatment of two and three wall intrabony defects. J Int Oral Health, 7(4), 32-37.

Eren, G., Tervahartiala, T., Sorsa, T. & Atilla, G. (2015). Cytokine (interleukin-1beta) and MMP levels in gingival crevicular fluid after use of platelet-rich fibrin or connective tissue graft in the treatment of localized gingival recessions. J Periodontal Res, 51(4), 481-488.

Hoaglin, D.R. & Lines, G.K. (2013). Prevention of Localized Osteitis in Mandibular Third-Molar Sites Using Platelet-Rich Fibrin. International Journal of Dentistry, 1-4.

Bilginaylar, K. & Uyanik, L.O. (2016). Evaluation of the effects of platelet-rich fibrin and piezosurgery on outcomes after removal of İmpacted mandibular third molars. British Journal of Oral and Maxillofacial Surgery, 54, 629-633.

Munoz, F., Jiménez, C., Espinoza, D., Vervelle, A., Beugnet, J. & Haidar, Z. (2016). Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): clinical effects on edema and pain. J Clin Exp Dent, 8(2), e119–124.

di Lauro, A.E., Abbate, D., Dell'Angelo, B., Iannaccone, G.A., Scotto, F. & Sammartino, G. (2015). Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: two case reports. J Med Case Reports, 9, 252.

Femminella, B., Iaconi, M.C., Di Tullio, M., Romano, L., Sinjari, B., D'Arcangelo, C., De Ninis, P. & Paolantonio, M. (2016). Clinical comparison of platelet-rich fibrin and a gelatin sponge in the management of palatal wounds after epithelialized free gingival graft harvest: a randomized clinical trial. J Periodontol, 87(2), 103-113.

Choukroun J, Diss A, Simonpieri A, Girard MO, Schoeffler C, Dohan SL, Dohan AJ, Mouhyi J, Dohan DM. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):299-303. doi: 10.1016/j.tripleo.2005.07.012. PMID: 16504861.

Koboyashi, M., Kawase, T., Horimizu, M., Okuda, K., Wolff, L.F. & Yoshie, H. (2012). A Proposed Protocol for the Standardized Preparation of PRF Membranes for Clinical Use. Biologicals, 40, 323-329.

Sareen V, K S, Saxena I, et al. (July 01, 2024) Role of Sticky Bone in the Management of Various Alveolar Bone Defects: A Systematic Review. Cureus 16(7): e63561. DOI 10.7759/cureus.63561

Malcangi, G.; Patano, A.;Palmieri, G.; Di Pede, C.; Latini, G.;Inchingolo, A.D.; Hazballa, D.; deRuvo, E.; Garofoli, G.; Inchingolo,F.; et al. Maxillary SinusAugmentation Using AutologousPlatelet Concentrates (Platelet-RichPlasma, Platelet-Rich Fibrin, andConcentrated Growth Factor)Combined with Bone Graft: ASystematic Review. Cells 2023, 12,1797. https://doi.org/10.3390/cells12131797

Soni R, Priya A, Yadav H, Mishra N, Kumar L. Bone augmentation with sticky bone and platelet-rich fibrin by ridge-split technique and nasal floor engagement for immediate loading of dental implant after extracting impacted canine. Natl J Maxillofac Surg2019;10:98-101

Egierska D, Perszke M, Mazur M, Duś-Ilnicka I. Platelet-rich plasma and platelet-rich fibrin in oral surgery: A narrative review. Dent Med Probl. 2023;60(1):177–186. doi:10.17219/dmp/147298

Oncu E, Erbeyoğlu A. Enhancement of immediate implant stability and recovery using platelet-rich fibrin. Int J Periodontics Restorative Dent. 2019;39(2):e58–e63. doi:10.11607/prd.2505

Egierska D, Perszke M, Mazur M, Duś-Ilnicka I. Platelet-rich plasma and platelet-rich fibrin in oral surgery: A narrative review. Dent Med Probl. 2023;60(1):177–186. doi:10.17219/dmp/147298

Mazor Z, Horowitz RA, Del Corso M, Prasad HS, Rohrer MD, Dohan Ehrenfest DM. Sinus floor augmentation with simultaneous implant placement using Choukroun's platelet-rich fibrin as the sole grafting material: a radiologic and histologic study at 6 months. J Periodontol. 2009 Dec;80(12):2056-64. doi: 10.1902/jop.2009.090252. PMID: 19961389.

Simonpieri A, Choukroun J, Del Corso M, Sammartino G, Dohan Ehrenfest DM. Simultaneous sinus-lift and implantation using microthreaded implants and leukocyte- and platelet-rich fibrin as sole grafting material: a six-year experience. Implant Dent. 2011 Feb;20(1):2-12. doi: 10.1097/ID.0b013e3181faa8af. PMID: 21278521.

Baru O, Buduru SD, Berindan-Neagoe I, Leucuta DC, Roman AR, Tălmăceanu D, Silvasan H, Badea ME. Autologous leucocyte and platelet rich in fibrin (L-PRF) - is it a competitive solution for bone augmentation in maxillary sinus lift? A 6-month radiological comparison between xenografts and L-PRF. Med Pharm Rep. 2024 Apr;97(2):222-233. doi: 10.15386/mpr-2719. Epub 2024 Apr 25. PMID: 38746034; PMCID: PMC11090277.

Assad M, Bitar W, Alhajj MN. Closure of oroantral communication using plateletrich fibrin: a report of two cases. Ann Maxillofac Surg 2017;7(1):117–9.

Shawky H, Seifeldin SA. Does platelet-rich fibrin enhance bone quality and quantityof alveolar cleft reconstruction? Cleft Palate Craniofac J 2016;53(5):597–606.

Albilia JB, Vizcaı´no CH-, Weisleder H, et al. Liquid platelet-rich fibrin injections as a treatment adjunct for painful temporomandibular joints: preliminary results. Cranio 2018;1–13

Giudice A, Antonelli A, Muraca D, Fortunato L. Usefulness of advanced-platelet rich fibrin (A-PRF) and injectable-platelet rich fibrin (i-PRF) in the management of a massive medication-related osteonecrosis of the jaw (MRONJ): A 5-years follow-up case report. Indian J Dent Res 2020;5:813-8

Zwittnig K, Mukaddam K, Vegh D, Herber V, Jakse N, Schlenke P, Zrnc TA, Payer M. Platelet-Rich Fibrin in Oral Surgery and Implantology: A Narrative Review. Transfus Med Hemother. 2022 Dec 22;50(4):348-359. doi: 10.1159/000527526. PMID: 37767284; PMCID: PMC10521222.

Gupta N, Agarwal S. Advanced-PRF: Clinical evaluation in impacted mandibular third molar sockets. J Stomatol Oral Maxillofac Surg. 2021 Feb;122(1):43-49. doi: 10.1016/j.jormas.2020.04.008. Epub 2020 Apr 29. PMID: 32360489.

Ahmed N, Gopalakrishna V, Shetty A, Nagraj V, Imran M, Kumar P. Efficacy of PRF vs PRF + Biodegradable Collagen Plug in Post-extraction Preservation of Socket. J Contemp Dent Pract. 2019 Nov 1;20(11):1323-1328. PMID: 31892686

Taşkaldıran, A., Koçyiğit, İ.D., Tüz, H., Tekin, U. & Atıl, F. (2011). Trombositten zengin plazma ve trombositten zengin fibrinin ağız, çene ve yüz cerrahisinde kullanım alanı. ADO Klinik Bilimler Dergisi, 5(3), 947-957.

Saluja H, Dehane V, Mahindra U. Platelet-Rich fibrin: A second generation platelet concentrate and a new friend of oral and maxillofacial surgeons. Ann Maxillofac Surg. 2011 Jan;1(1):53-7. doi: 10.4103/2231-0746.83158. PMID: 23482459; PMCID: PMC3591032.

Rodella, L.F. & Bonazza, V. (2015). Platelet Preparations in Dentistry: How? Why? Where? When?. World J Stomatol, 4(2), 39-55.

Yayınlanan

13 Şubat 2026

Lisans

Lisans