Ferroptosis

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Liao P, Wang W, Wang W, Kryczek I, Li X, Bian Y, Sell A, Wei S, Grove S, Johnson JK, Kennedy PD. CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4. Cancer cell. 2022 Apr 11;40(4):365-78.

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Wang Y, Zhang M, Bi R, Su Y, Quan F, Lin Y, Yue C, Cui X, Zhao Q, Liu S, Yang Y. ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury. Redox biology. 2022 May 1;51:102262.

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Zhou Z, Ye TJ, DeCaro E, Buehler B, Stahl Z, Bonavita G, Daniels M, You M. Intestinal SIRT1 deficiency protects mice from ethanol-induced liver injury by mitigating ferroptosis. The American Journal of Pathology. 2020 Jan 1;190(1):82-92.

Wang J, Zhu Q, Li R, Zhang J, Ye X, Li X. YAP1 protects against septic liver injury via ferroptosis resistance. Cell & Bioscience. 2022 Oct 1;12(1):163.

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Fang X, Wang H, Han D, Xie E, Yang X, Wei J, Gu S, Gao F, Zhu N, Yin X, Cheng Q. Ferroptosis as a target for protection against cardiomyopathy. Proceedings of the National Academy of Sciences. 2019 Feb 12;116(7):2672-80.

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Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nature chemical biology. 2017 Jan;13(1):91-8.

Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nature chemical biology. 2017 Jan;13(1):81-90.

Yuan H, Li X, Zhang X, Kang R, Tang D. Identification of ACSL4 as a biomarker and contributor of ferroptosis. Biochemical and biophysical research communications. 2016 Sep 23;478(3):1338-43

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Tesfay L, Paul BT, Konstorum A, Deng Z, Cox AO, Lee J, Furdui CM, Hegde P, Torti FM, Torti SV. Stearoyl-CoA desaturase 1 protects ovarian cancer cells from ferroptotic cell death. Cancer research. 2019 Oct 15;79(20):5355-66.

Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA. Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state. Cell chemical biology. 2019 Mar 21;26(3):420-32.

Zou Y, Henry WS, Ricq EL, Graham ET, Phadnis VV, Maretich P, Paradkar S, Boehnke N, Deik AA, Reinhardt F, Eaton JK. Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. Nature. 2020 Sep 24;585(7826):603-8.

Bai Y, Meng L, Han L, Jia Y, Zhao Y, Gao H, Kang R, Wang X, Tang D, Dai E. Lipid storage and lipophagy regulates ferroptosis. Biochemical and biophysical research communications. 2019 Jan 22;508(4):997-1003.

Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Glutaminolysis and transferrin regulate ferroptosis. Molecular cell. 2015 Jul 16;59(2):298-308.

Song X, Liu J, Kuang F, Chen X, Zeh HJ, Kang R, Kroemer G, Xie Y, Tang D. PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis. Cell Reports. 2021 Feb 23;34(8).

Lin Z, Liu J, Kang R, Yang M, Tang D. Lipid metabolism in ferroptosis. Advanced Biology. 2021 Aug;5(8):2100396.

Chu B, Kon N, Chen D, Li T, Liu T, Jiang L, Song S, Tavana O, Gu W. ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nature cell biology. 2019 May;21(5):579-91.

Wenzel SE, Tyurina YY, Zhao J, Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K. PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals. Cell. 2017 Oct 19;171(3):628-41.

Kuang F, Liu J, Xie Y, Tang D, Kang R. MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells. Cell chemical biology. 2021 Jun 17;28(6):765-75.

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Chen X, Yu C, Kang R, Tang D. Iron metabolism in ferroptosis. Frontiers in cell and developmental biology. 2020 Oct 7;8:590226.

Sun X, Ou Z, Xie M, Kang R, Fan Y, Niu X, Wang H, Cao L, Tang D. HSPB1 as a novel regulator of ferroptotic cancer cell death. Oncogene. 2015 Nov;34(45):5617-25.

Wang Y, Liu Y, Liu J, Kang R, Tang D. NEDD4L-mediated LTF protein degradation limits ferroptosis. Biochemical and biophysical research communications. 2020 Oct 22;531(4):581-7.

Alvarez SW, Sviderskiy VO, Terzi EM, Papagiannakopoulos T, Moreira AL, Adams S, Sabatini DM, Birsoy K, Possemato R. NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis. Nature. 2017 Nov 30;551(7682):639-43.

Hou W, Xie Y, Song X, Sun X, Lotze MT, Zeh III HJ, Kang R, Tang D. Autophagy promotes ferroptosis by degradation of ferritin. Autophagy. 2016 Aug 2;12(8):1425-8.

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Li L, Hao Y, Zhao Y, Wang H, Zhao X, Jiang Y, Gao F. Ferroptosis is associated with oxygen-glucose deprivation/reoxygenation-induced Sertoli cell death. International journal of molecular medicine. 2018 May;41(5):3051-62.

Li J, Liu J, Xu Y, Wu R, Chen X, Song X, Zeh H, Kang R, Klionsky DJ, Wang X, Tang D. Tumor heterogeneity in autophagy-dependent ferroptosis. Autophagy. 2021 Nov 2;17(11):3361-74.

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Liu J, Song X, Kuang F, Zhang Q, Xie Y, Kang R, Kroemer G, Tang D. NUPR1 is a critical repressor of ferroptosis. Nature communications. 2021 Jan 28;12(1):647.

Yuan H, Li X, Zhang X, Kang R, Tang D. CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation. Biochemical and biophysical research communications. 2016 Sep 16;478(2):838-44.

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