Hemodiyaliz Tedavisi Alan Çocuklarda Büyüme Geriliği ve Kanıta Dayalı Tedavi Bakım Uygulamaları
Özet
Büyüme geriliği, kronik böbrek hastalığı olan çocuklarda görülen en önemli komplikasyonlardan biridir. Çocuk ne kadar küçükse büyüme geriliğinin şiddeti de o kadar yüksektir. Bu nedenle her yaş aralığında ve böbrek hastalığının tüm evrelerinde büyüme dikkatli bir şekilde izlenmeli, etkili önlem ve müdahaleler zamanında yapılmalıdır. Büyüme geriliğinin temel tedavisi böbrek fonksiyonlarının korunması, kan basıncının kontrolü, yaşa göre yeterli beslenmenin sağlanması, sıvı elektrolit dengesinin sağlanması, metabolik asidozun düzeltilmesi, hormon değerlerinin kontrolü, rekombinant insan büyüme hormonu tedavisi ile böbrek transplantasyonu olan çocuklarda, steroidin minimum dozlardaki immünosupresif tedavilerini içermektedir. Erken dönemlerde böbrek transplantasyonu önerilmelidir.
Referanslar
Akchurin OM. Chronic kidney disease and dietary measures to ımprove outcomes. Pediatr Clin North Am. 2019 Feb;66(1):247-267. doi: 10.1016/j.pcl.2018.09.007.
Liu YM, Chang HJ, Wang RH, et al. Role of resilience and social support in alleviating depression in patients receiving maintenance hemodialysis. Ther Clin Risk Manag. 2018; 14: 441–451. doi: 10.2147/TCRM.S152273
Ammirati AL. Chronic kidney disease. Rev Assoc Med Bras (1992). 2020:13;66Suppl 1(Suppl 1): s03-s09. doi: 10.1590/1806-9282.66.S1.3.
Evans M, Lewis RD, Morgan AR, et al. A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives. Adv Ther. 2022;39(1):33-43. doi: 10.1007/s12325-021-01927-z.
T.C. Sağlık Bakanlığı, Türkiye Halk Sağlığı Genel Müdürlüğü. Türkiye böbrek hastalıkları önleme ve kontrol programı. eylem planı (2018-2023). (26/01/2024 tarihinde https://hsgm.saglik.gov.tr/depo/birimler/kronik-hastaliklar-ve-yasli-sagligi db/Dokumanlar/Kitaplar/Turkiye_Bobrek_Hastaliklari_Onleme_ve_Kontrol_Programi_2018-2023.pdf adresinden ulaşılmıştır).
U.S. Department of health and human services end stage renal disease: Chapter 1. Incidence, prevalence, patient characteristics, and treatment modalities. (26/10/2024 tarihinde https://usrds-adr.niddk.nih.gov/2023/end-stage-renal-disease/1-incidence-prevalence-patient-characteristics-and-treatment-modalities adresinden ulaşılmıştır).
Ateş K, Seyahi N, Koçyiğit İ. Türkiye’de nefroloji, diyaliz ve transplantasyon T.C. Sağlık Bakanlığı ve Türk Nefroloji Derneği Ortak Raporu, Registry. (25/01/2024 tarihinde 2022 https://nefroloji.org.tr/uploads/pdf/REGISTRY2022_web.pdf adresinden ulaşılmıştır).
NIH USRDS End stage renal disease: Chapter 8 ESRD among children and adolescents. (15/02/2024 tarihinde https://usrds-adr.niddk.nih.gov/2023/end-stage-renal-disease/8-esrd-among-children-and-adolescents adresinden ulaşılmıştır).
Drube J, Wan M, Bonthuis M, et al. European society for paediatric nephrology chronic kidney disease mineral and bone disorders, dialysis, and transplantation working groups. clinical practice recommendations for growth hormone treatment in children with chronic kidney disease. Nat Rev Nephrol. 2019;15(9):577-589. doi: 10.1038/s41581-019-0161-4.
Haffner D. Strategies for optimizing growth in children with chronic kidney disease. Front Pediatr. 2020; 8: 399. doi: 10.3389/fped.2020.00399.
Chand DP, Valentini RP. Chronic kidney disease: Treatment of Comorbidities II (hypertension, anemia, and electrolyte management). Pediatric Nephrology. 2019;5: 93–101.
Bacchetta J, Harambat J, Cochat P, et al. The consequences of chronic kidney disease on bone metabolism and growth in children. Nephrol Dial Transplant. 2012;27(8):3063–3071.doi: 10.1093/ndt/gfs299.
Mahesh S, Kaskel F. Growth hormone axis in chronic kidney disease. Pediatr Nephrol. 2008;23(1):41–48. doi: 10.1007/s00467-007-0527-x.
Hall JE. Guyton ve Hall Tıbbi Fizyoloji. (Berrak Çağlayan Yeğen, Çev. Ed.). Ankara: Güneş Tıp Kitabevleri;2017
Hodson EM, Willis NS, Craig JC. Growth hormone for children with chronic kidney disease. Cochrane Database Syst Rev. 2012;2:CD003264.
Rees L, Schaefer F, Schmitt CP, et al. Chronic dialysis in children and adolescents: challenges and outcomes. Lancet Child Adolesc Health. 2017;1(1):68-77. doi: 10.1016/S2352-4642(17)30018-4.
Bonthuis M, Harambat J, Jager KJ, et al. Growth in children on kidney replacement therapy: a review of data from patient registries. Pediatr Nephrol. 2021;36(8):2563–2574. doi:10.1007/s00467-021-05099-4.
Feldt-Rasmussen B, Lange M, Sulowicz W, et al. APCD Study Group. Growth hormone treatment during hemodialysis in a randomized trial improves nutrition, quality of life, and cardiovascular risk. J Am Soc Nephrol. 2007;18(7):2161-71. doi: 10.1681/ASN.2006111207. 17554147.
Van Den Belt SM, Heerspink HJL, Kirchner M, et al. Discontinuation of RAAS Inhibition in Children with Advanced CKD. Discontinuation of RAAS inhibition in children with advanced CKD. Clin J Am Soc Nephrol. 2020;15(5):625-632. doi: 10.2215/CJN.09750819.
Shaw V, Polderman N, Renken-Terhaerdt J, et al. Energy and protein requirements for children with CKD stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce. Pediatr Nephrol. 2020; 35:519–31. 10.1007/s00467-019-04426-0.
Shroff R, Wan M, Nagler EV, et al. Clinical practice recommendations for treatment with active vitamin D analogues in children with chronic kidney disease Stages 2-5 and on dialysis. Nephrol Dial Transplant. 2017; 32:1114–27. 10.1093/ndt/gfx080.
Shroff R, Wan M, Nagler EV, et al. Clinical practice recommendations for native vitamin D therapy in children with chronic kidney disease Stages 2-5 and on dialysis. Nephrol Dial Transplant. (2017) 32:1098–113. 10.1093/ndt/gfx065.
Nelms CL, Shaw V, Greenbaum LA et al. Assessment of nutritional status in children with kidney diseases—clinical practice recommendations from the Pediatric Renal Nutrition Taskforce. Pediatr Nephrol. 2021;36(4):995-1010. doi: 10.1007/s00467-020-04852-5.
David V, Salusky IB, Malluche H et al. Renal osteodystrophy: something old, something new, something needed. Curr Opin Nephrol Hypertens. 2023;1;32(6): 559-564.doi: 10.1097/MNH.0000000000000918.
KDIGO 2017 Clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder (CKD-MBD) Kidney Int Suppl. 2017;7(1).
Hattori M. Hemoglobin target in children with chronic kidney disease: valuable new information. Kidney Int. 2017;91(1):16–8.
Fischbach M, Wühl E, Sylvie C. et al. Efficacy and long-term safety of C.E.R.A. maintenance in pediatric hemodialysis patients with anemia of CKD. Clin J Am Soc Nephrol. 2018 6;13(1):81–90. doi: 10.2215/CJN.03570417.
Lee KH, Park E, Choi HJ et al. Anemia and ıron deficiency in children with chronic kidney disease (CKD): Data from the Know-Ped CKD Study. J. Clin. Med. 2019; 8(2): 152. https://doi.org/10.3390/jcm8020152.
Ambarsari CG, Trihono PP, Kadaristiana A et al. Low-dose maintenance ıntravenous ıron therapy can prevent anemia in children with end-stage renal disease undergoing chronic hemodialysis. International Journal of Nephrology. 2020; 1:2020:3067453.doi: 10.1155/2020/3067453.
Atkinson MA, Warady BA. Anemia in chronic kidney disease. Pediatr Nephrol. 2018;33(2): 227-238.doi: 10.1007/s00467-017-3663-y.
Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group (2012) KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney Int Suppl 2:279–335.
Twichell SA, Hunt EAK, Martz K et al. Effects of changes in adult erythropoietin dosing guidelines on erythropoietin dosing practices, anemia, and blood transfusion in children on hemodialysis: findings from North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS). Pediatr Nephrol.2020;35(2):297-303. doi: 10.1007/s00467-019-04359-8.
Lin J, Cheng Z, Ding X, et al. Acid-base and electrolytemanagements in chronic kidney disease and end-stage renal disease: case-based discussion; Blood Purif. 2018;45(1-3):179-186.https://doi.org/10.1159/000485155.
Rodig NM, McDermott KC, Schneider MF et al. Growth in children with chronic kidney disease: a report from the chronic kidney disease in children study. Pediatr Nephrol. 2014; 29(10):1987-95. doi: 10.1007/s00467-014-2812-9.
Dandamudi R, Twombley K, Flynn JT et al. Physician knowledge, attitudes, and practices regarding physical activity restrictions in pediatric hemodialysis patients. Hemodialysis International. 2023;27(4):345-351. doi:10.1111/hdi.13095.
Ikizler TA. Exercise as an anabolic ıntervention in patients with end-stage renal disease. J Ren Nutr. 2011; 21(1):52–6.doi: https://doi.org/10.1053/j.jrn.2010.10.012.
Painter P, Johansen KL. Improving physical functioning: time to be a part of routine care. Am J Kidney Dis. 2006;48(1):167-70. doi: 10.1053/j.ajkd.2006.05.004.
Chadban SJ, Ahn C, Axelrod DA. KDIGO Clinical practice guideline on the evaluation and management of candidates for kidney transplantation. Transplantation. 2020;104(4S1 Suppl 1): S11-S103.doi: 10.1097/TP.0000000000003136.
Bonthuis M, Groothoff JW, Ariceta G et al. Growth patterns after kidney transplantation in european children over the past 25 years: An ESPN/ERA-EDTA Registry Study. Transplantation. 2020;104(1):137-144. doi: 10.1097/TP.0000000000002726.
Webb NJA, Douglas SE, Rajai A et al. Corticosteroid-free kidney transplantation ımproves growth: 2-year follow-up of the twıst randomized controlled trial transplantation. 2015;99(6):1178-85. doi: 10.1097/TP.0000000000000498.
Sarwal MM, Ettenger R, Dharnidharka V. Complete steroıd avoıdance ıs effectıve and safe ın chıldren wıth renal transplants: a multıcenter randomızed trıal wıth 3 year follow up. Am J Transplant. 2012;12(10):2719–2729. doi: 10.1111/j.1600-6143.2012.04145.x.
Bolacalı ET, Küçükoğlu S. Roy adaptasyon modeline göre hemodiyaliz tedavisi alan çocuk ve ailesinin hemşirelik tanılama süreci: Olgu sunumu. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2023;12(3):1488 – 1496.
Tayaz E, Koç A. Hemodiyaliz tedavisi alan kronik böbrek yetmezliği hastalarında semptom yönetimi ve hemşirelik. Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi. 2020;23(1):147-156. DOI: 10.17049/ataunihem.441384.
Nural N. Nefroloji Hemşireliğinde kanıta dayalı uygulamalar. Nefroloji Hemşireliği Dergisi 2015;47-52
Kesik G, Özdemir L. İntradiyalitik hipotansiyon ve önlemeye yönelik hemşirelik yaklaşımları. Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi. 2019;22(1):58-63.