Komplike Karaciğer Kist Hidatiği Sebebiyle Parsiyel Kistektomi ve Omentopeksi Yapılmış Hastada Postoperatif Gelişen Yüksek Debili Safra Fistülünün Minimal İnvaziv Girişimsel ve Endoskopik Yöntemlerle Tedavisi
Özet
Serolojik ve klinik aktif, komplike, çapı yaklaşık >10 cm Cystic Echinococcus Gharbi Tip 3 (CE 3B) karaciğer kist hidatik tanısı ile kliniğimize başvuran, medikal tedavi almakta olan 50 yaşında kadın hastada ileri tetkik ve tedavi planlandı. PAİR (Puncture, Aspiration, İnjection, Reaspiration) sonrası safra fistülü tespit edilen, fistül yönetimi, MoCat (Modified Catheterization technique) + ERCP – Endoskopik sfinkterotomiye eklenen biliyer stent şeklinde seçilen hastada safra fistülü sebat etmesi üzerine cerrahi kararı alındı. Açık cerrahi metodla opere edilen hastaya parsiyel kistektomi yapıldı. Vaka boyunca kaviteden safra kaçağı gözlenmedi. Omentopeksi ve drenaj eklenerek vaka sonlandırıldı. Postoperatif erken dönemde yüksek debili (> 500 cc) safra fistülü devam eden hastaya önce ERCP ile selektif kateterizasyon ve ardından PTK ile eksternal drenaj uygulandı. Omentopeksi ve cerrahi drenaj ile birlikte postoperatif dönemde uygulanan minimal invaziv girişimsel ve endoskopik metodlarla yakalşık 4 hafta içinde fistül kontrol altına alındı. Komplike karaciğer kist hidatiklerinde tüm tedavi sürecinde cerrahiye eşlik eden minimal invaziv girişimsel ve endoskopik metodları hasta ve literatür eşliğinde tartıştık.
Referanslar
Sokouti M, Pezeshkian M, G K, Golzari SEJ. Surgical procedures and postoperative complications in patients with giant and non-giant pulmonary hydatid cysts. Life Sci J 2013;10:138–42.
Palanivelu C, Jani K, Malladi V, Senthilkumar R, Rajan PS, Sendhilkumar K, et al. Laparoscopic management of hepatic hydatid disease. JSLS 2006;10:56–62.
Chen W, Xusheng L. Laparoscopic surgical techniques in patients with hepatic hydatid cyst. Am J Surg 2007;194:243–7.
Govindasamy A, Bhattarai PR, John J. Liver cystic echinococcosis: a parasitic review. Ther Adv Infect Dis. 2023 May 11;10:
Bhutani N, Kajal P. Hepatic echinococcosis: a review. Ann Med Surg 2018; 36: 99–105.
Larrieu E, Zanini F. 2012. Critical analysis of cystic echinococcosis control programs and praziquantel use in South America, 1974-2010. Rev Panam Salud Publica 31:81–87.
Tian T., Miao L., Wang W., Zhou X. Global, Regional and National Burden of Human Cystic Echinococcosis from 1990 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019. Trop. Med. Infect. Dis. 2024;9:87.
Siles-Lucas M, Casulli A, Cirilli R, Carmena D. 2018. Progress in the pharmacological treatment of human cystic and alveolar echinococcosis: compounds and therapeutic targets. PLoS Negl Trop Dis 12:e0006422.
Horton J. 2003. Albendazole for the treatment of echinococcosis. Fundam Clin Pharmacol 17:205–212.
Vuitton D, Bresson-Hadni S. 2014. Alveolar echinococcosis: evaluation of therapeutic strategies. Expert Opin Orphan Drugs 2:67–86.
Kern P, Menezes da Silva A, Akhan O, Mullhaupt B, Vizcaychipi KA, Budke C, Vuitton DA. 2017. The echinococcoses: diagnosis, clinical management and burden of disease. Adv Parasitol 96:259–369.
Velasco-Tirado V, Lopez-Bernus A, Romero-Alegría Á. Medical treatment of cystic echinococcosis: systematic review and meta-analysis. BMC Infect Dis 2018; 18.
Julien C, Le Treut YP, Bourgouin S, et al. Closed cyst resection for liver hydatid disease: a new standard. J Gastrointest Surg 2021; 25: 436–446.
Mönnink GLE, Stijnis C, van Delden OM, et al. Percutaneous versus surgical interventions for hepatic cystic echinococcosis: a systematic review and meta-analysis. Cardiovasc Intervent Radiol 2021; 44: 1689–1696.
Öztürk G, Uzun MA, Özkan ÖF, et al. Turkish HPB Surgery Association consensus report on hepatic cystic echinococcosis (HCE). Turk J Surg 2022; 38: 101–120.
Köroğlu M, Erol B, Gürses C, et al. Hepatic cystic echinococcosis: percutaneous treatment as an outpatient procedure. Asian Pac J Trop Med 2014; 7: 212–215.
Balli O, Balli G, Cakir V, et al. Percutaneous treatment of giant cystic echinococcosis in liver: catheterization technique in patients with CE1 and CE3a. Cardiovasc Intervent Radiol 2019; 42: 1153–1159.
Kahriman G, Ozcan N, Dogan S, et al. Percutaneous treatment of liver hydatid cysts in 190 patients: a retrospective study. Acta Radiol 2017; 58: 676–684
Rooh ul M, Kamran K, Khalil J, Gul T, Farid S. Laparoscopic treatment of hepatic hydatid cyst. J Coll Physicians Surg Pak 2011;21:468–71.
Vagholkar K, Pawanarkar A, Chougle Q, et al. Surgery for intra-abdominal hydatid disease: a single centre experience. Int J Res Med Sci 2016; 4: 4241–4245. [
Tagliacozzo S, Miccini M, Amore Bonapasta S, Gregori M, Tocchi A. 2011. Surgical treatment of hydatid disease of the liver: 25 years of experience. Am J Surg 201:797–804.
Katkhouda N, Fabiani P, Benizri E, Mouiel J. 1992. Laser resection of a liver hydatid cyst under videolaparoscopy. Br J Surg 79:560–561.
Casciola L, Patriti A, Ceccarelli G, Bartoli A, Ceribelli C, Spaziani A. 2011. Robot-assisted parenchymal-sparing liver surgery including lesions located in the posterosuperior segments. Surg Endosc 25:3815–3824.
Brunetti E, Kern P, Vuitton DA. Writing Panel for the W-I. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 2010;114:1–16.
Agarwal N, Sharma CB, Garg S, et al. Endoscopic manage- ment of postoperative bile leaks. Hepatobiliary Pancreat Dis Int. 2006;5:273–277.
Dziri C, Haouet K, Fingerhut A. Treatment of hydatid cyst of the liver: where is the evidence. World J Surg. 2004;28:731–736.
Atlı M, Kama NA, Yuksek YN, et al. Intrabiliary rupture of a hepatic hydatid cyst. Arch Surg. 2001;136:1249–1255.
Hamamci OE, Besim H, Sonisik M, et al. Occult intrabiliary rupture of hydatid cysts in the liver. World J Surg. 2005; 29:224–226.
Rinaldi F, Brunetti E, Neumayr A, Maestri M, Goblirsch S, Tamarozzi F. Cystic echinococcosis of the liver: A primer for hepatologists. World J Hepatol. 2014;6:293–305.
World Health Organization. PAIR: Puncture, Aspiration, Injection, Re- Aspiration. An option for the treatment of Cystic echinococcosis. WHO/CDS/CSR/APH/2001.6 Geneva, 2003: 1-4.
Giorgio A, de Stefano G, Esposito V, Liorre G, Di Sarno A, Giorgio V, Sangiovanni V, Iannece MD, Mariniello N. Long-term results of percutaneous treatment of hydatid liver cysts: a single center 17 years experience. Infection. 2008;36:256–261.
Nasseri Moghaddam S, Abrishami A, Malekzadeh R. Percutaneous needle aspiration, injection, and reaspiration with or without benzimidazole coverage for uncomplicated hepatic hydatid cysts. Cochrane Database Syst Rev. 2006;2:CD003623.
Junghanss T, da Silva AM, Horton J, Chiodini PL, Brunetti E. Clinical management of cystic echinococcosis: state of the art, problems, and perspectives. Am J Trop Med Hyg. 2008;79:301–311.
Kumar R, Reddy SN, Thulkar S. Intrabiliary rupture of hydatid cyst: diagnosis with MRI and hepatobiliary isotope study. Br J Radiol. 2002;75:271–274.
Kilic M, Yoldas O, Koc M, Keskek M, Karakose N, Ertan T, Gocmen E, Tez M. Can biliary-cyst communication be predicted before surgery for hepatic hydatid disease: does size matter? Am J Surg. 2008;196:732–735.
Schipper HG, Laméris JS, van Delden OM, Rauws EA, Kager PA. Percutaneous evacuation (PEVAC) of multivesicular echinococcal cysts with or without cystobiliary fistulas which contain non-drainable material: first results of a modified PAIR method. Gut. 2002;50:718–723.
Brunetti E, Garcia HH, Junghanss T. Cystic echinococcosis: chronic, complex, and still neglected. PLoS Negl Trop Dis. 2011;5:e1146.
Rodriguez AN, Sanchez AL, Alguacil LV, et al. Effectiveness of endoscopic sphincterotomy in complicated hepatic hydatid disease. Gastrointest Endosc. 1998;48:593–597.
Saritas U, Parlak E, Akoglu M, et al. Effectiveness of endoscopic treatment modalities in complicated hepatic hydatid disease after surgical intervention. Endoscopy. 2001;33: 858–863
Becker K, Frieling T, Saleh A, et al. Resolution of hydatid liver cyst by spontaneous rupture into the biliary tract. J Hepatol. 1997;26:1408–1412
Cicek B, Parlak E, Disibeyaz S, et al. Endoscopic therapy of hepatic hydatid cyst disease in preoperative and postoperative settings. Dig Dis Sci. 2007;52:931–935.
Akcakaya A, Sahin M, Karakelleoglu A, et al. Endoscopic stenting for selected cases of biliary fistula after hepatic hydatid surgery. Surg Endosc. 2006;20:1415–1418.
Ferrer Inaebnit E, Molina Romero FX, Segura Sampedro JJ, González Argenté X, Morón Canis JM. A review of the diagnosis and management of liver hydatid cyst. Rev Esp Enferm Dig. 2022 Jan;114(1):35-41.
Tuxun T, Zhang JH, Zhao JM, Tai QW, Abudurexti M, Ma HZ, Wen H. 2014. World review of laparoscopic treatment of liver cystic echinococcosis—914 patients. Int J Infect Dis 24C:43–50.
Gupta N, Javed A, Puri S, Jain S, Singh S, Agarwal AK. 2011. Hepatic hydatid: PAIR, drain or resect? J Gastrointest Surg 15:1829–1836.
Zaharie F, Bartos D, Mocan L, Zaharie R, Iancu C, Tomus C. Open or laparoscopic treatment for hydatid disease of the liver? A 10-year single-institution experience. Surg Endosc 2013;27:2110–6.
Senthilnathan P, Inamdar S, Nalankilli VP, Vijay A, Rajapandian S, Parthsarathi R, et al. Long-term results of hepatic hydatid disease managed using palanivelu hydatid system: Indian experience in tertiary center. Surg Endosc 2014;28:2832–9.
Tuxun T, Aji T, Tai QW, Zhang JH, Zhao JM, Cao J, et al. Conventional versus laparoscopic surgery for hepatic hydatidosis: a 6-year single-center experience. J Gastrointest Surg 2014;18:1155–60.
Küçük C, Yılmaz N, Akyıldız H, Sözüer E. Surgical treatment in liver cyst hydatid cases: analysis of 276 patients. Erciyes Tıp Dergisi 2008;30:170–4.
Baskaran V, Patnaik PK. Feasibility and safety of laparoscopic management of hydatid disease of the liver. JSLS 2004;8:359–63.
Dolay K, Akcakaya A, Soybir G, et al. Endoscopic sphincter- otomy in the management of postoperative biliary fistula: a complication of hepatic hydatid disease. Surg Endosc. 2002; 16:985–988.
Tekant Y, Bilge O, Acarlı K, et al. Endoscopic sphincterotomy in the treatment of postoperative biliary fistulas of hepatic hydatid disease. Surg Endosc. 1996;10:909–911.
Rodriguez AN, Sanchez AL, Alguacil LV, et al. Effectiveness of endoscopic sphincterotomy in complicated hepatic hydatid disease. Gastrointest Endosc. 1998;48:593–597.
Akcakaya A, Sahin M, Karakelleoglu A, et al. Endoscopic stenting for selected cases of biliary fistula after hepatic hydatid surgery. Surg Endosc. 2006;20:1415–1418.
Bilsel Y, Bulut T, Yamaner S, et al. ERCP in the diagnosis and management of complications after surgery for hepatic echinococcosis. Gastrointest Endosc. 2003;57:210–213 .
Foutch GP, Harlen JR, Hoefer M. Endoscopic therapy for patients with a postoperative biliary leak. Gastrointest Endosc. 1993;39:416–421.
Yorganci K, Sayek I. Surgical treatment of hydatid cysts of the liver in the era of percutaneous treatment. Am J Surgery. 2002;184:63–69.
Ozaslan E, Bayraktar Y. Endoscopic therapy in the manage- ment of hepatobiliary hydatid disease. J Clin Gastroenterol. 2002;35:160–174.