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Chiari P, Fellahi JL. Myocardial protection in cardiac surgery: a comprehensive review of current therapies and future cardioprotective strategies. Front Med-Lausanne. 2024; 11.

Chowdhury UK, Malik V, Yadav R, et al. Myocardial injury in coronary artery bypass grafting: on-pump versus off-pump comparison by measuring high-sensitivity C-reactive protein, cardiac troponin I, heart-type fatty acid-binding protein, creatine kinase-MB, and myoglobin release. J Thorac Cardiovasc Surg. 2008; 135: 1110-1119, 1119 e1111-1110.

Heusch G. The Coronary Circulation as a Target of Cardioprotection. Circ Res. 2016; 118: 1643-1658.

Buckberg GD. Update on Current Techniques of Myocardial Protection. Ann Thorac Surg. 1995; 60: 805-814.

Hausenloy DJ, Yellon DM. Ischaemic conditioning and reperfusion injury. Nat Rev Cardiol. 2016; 13: 193-209.

Kloner RA, Fishbein MC, Hare CM, et al. Early ischemic ultrastructural and histochemical alterations in the myocardium of the rat following coronary artery occlusion. Exp Mol Pathol. 1979; 30: 129-143.

Hajar R. Evolution of Myocardial Infarction and its Biomarkers: A Historical Perspective. Heart Views. 2016; 17: 167-172.

Marzilli M, Sabbah HN, Stein PD. Supply-demand balance of subendocardial muscle: estimation from intramyocardial pressure. J Thorac Cardiovasc Surg. 1980; 79: 803-808.

Warisawa T, Cook CM, Akashi YJ, et al. Past, Present and Future of Coronary Physiology. Rev Esp Cardiol (Engl Ed). 2018; 71: 656-667.

Stanley WC, Recchia FA, Lopaschuk GD. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev. 2005; 85: 1093-1129.

Buckberg GD, Brazier JR, Nelson RL, et al. Studies of the effects of hypothermia on regional myocardial blood flow and metabolism during cardiopulmonary bypass. I. The adequately perfused beating, fibrillating, and arrested heart. J Thorac Cardiovasc Surg. 1977; 73: 87-94.

Takaoka H, Takeuchi M, Odake M, et al. Comparison of hemodynamic determinants for myocardial oxygen consumption under different contractile states in human ventricle. Circulation. 1993; 87: 59-69.

Wang J, Liu H, Xiang B, et al. Keeping the heart empty and beating improves preservation of hypertrophied hearts for valve surgery. J Thorac Cardiovasc Surg. 2006; 132: 1314-1320.

Braunwald E, Kloner RA. The stunned myocardium: prolonged, postischemic ventricular dysfunction. Circulation. 1982; 66: 1146-1149.

Rahimtoola SH, La Canna G, Ferrari R. Hibernating myocardium - Another piece of the puzzle falls into place. J Am Coll Cardiol. 2006; 47: 978-980.

Yellon DM, Hausenloy DJ. Mechanisms of disease: Myocardial reperfusion injury. New Engl J Med. 2007; 357: 1121-1135.

Zweier JL, Talukder MAH. The role of oxidants and free radicals in reperfusion injury. Cardiovasc Res. 2006; 70: 181-190.

Matter MA, Paneni F, Libby P, et al. Inflammation in acute myocardial infarction: the good, the bad and the ugly. Eur Heart J. 2024; 45: 89-103.

Tune JD, Gorman MW, Feigl EO. Matching coronary blood flow to myocardial oxygen consumption. J Appl Physiol (1985). 2004; 97: 404-415.

De Bruyne B, Pijls NHJ, Heyndrickx GR, et al. Pressure-derived fractional flow reserve to assess serial epicardial stenoses - Theoretical basis and animal validation. Circulation. 2000; 101: 1840-1847.

Fokkema DS, VanTeeffelen JWGE, Dekker S, et al. Diastolic time fraction as a determinant of subendocardial perfusion. Am J Physiol-Heart C. 2005; 288: H2450-H2456.

Kaneko A, Tanaka H, Onishi T, et al. Subendocardial dysfunction in patients with chronic severe aortic regurgitation and preserved ejection fraction detected with speckle-tracking strain imaging and transmural myocardial strain profile. Eur Heart J-Card Img. 2013; 14: 339-346.

Samanidis G, Georgiopoulos G, Bousounis S, et al. Outcomes after intra-aortic balloon pump insertion in cardiac surgery patients. Rev Bras Ter Intensiva. 2020; 32: 542-550.

Engelman R, Baker RA, Likosky DS, et al. The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of ExtraCorporeal Technology: Clinical Practice Guidelines for Cardiopulmonary Bypass-Temperature Management During Cardiopulmonary Bypass. J Cardiothor Vasc An. 2015; 29: 1104-1113.

Angeli E, Lueck S, Gargiulo GD. Different strategies of myocardial protection: the age of perfectionism. J Thorac Dis. 2018; 10: 1211-1213.

Uyar I, Mansuroglu D, Kirali K, et al. Aspartate and glutamate-enriched cardioplegia in left ventricular dysfunction. J Cardiac Surg. 2005; 20: 337-344.

Shahbaz Ahmad Khilji, Muhammad Fahad Ghaffar. Enhancement of myocardial recovery with terminal ‘hot shot’ cardioplegia. Journal Of Shalamar Medical and Dental College. 2024; 5: 89-94.

Cassese M, Martinelli G, Nasso G, et al. Topical cooling for myocardial protection: the results of a prospective randomized study of the "shallow technique". J Card Surg. 2006; 21: 357-362.

Buckberg GD. Normothermic blood cardioplegia. Alternative or adjunct? J Thorac Cardiovasc Surg. 1994; 107: 860-867.

Calafiore AM, Pelini P, Foschi M, et al. Intermittent Antegrade Warm Blood Cardioplegia: What Is Next? Thorac Cardiovasc Surg. 2020; 68: 232-234.

Melrose DG, Dreyer B, Bentall HH, et al. Elective cardiac arrest. Lancet. 1955; 269: 21-22.

Jansson E, Bomfim V, Schmidt W, et al. Myocardial energy metabolism in the induction phase of cardioplegia in relation to myocardial temperature during open heart surgery. Clin Physiol. 1987; 7: 43-49.

Marazzi G, Rosanio S, Caminiti G, et al. The role of amino acids in the modulation of cardiac metabolism during ischemia and heart failure. Curr Pharm Des. 2008; 14: 2592-2604.

Svedjeholm R, Huljebrant I, Hakanson E, et al. Glutamate and high-dose glucose-insulin-potassium (GIK) in the treatment of severe cardiac failure after cardiac operations. Ann Thorac Surg. 1995; 59: S23-30.

Ji B, Liu J, Liu M, et al. Effect of cold blood cardioplegia enriched with potassium-magnesium aspartate during coronary artery bypass grafting. J Cardiovasc Surg (Torino). 2006; 47: 671-675.

Snyder HE, Smithwick W, 3rd, Wingard JT, et al. Retrograde coronary sinus perfusion. Ann Thorac Surg. 1988; 46: 389-390.

Bhayana JN, Kalmbach T, Booth FVM, et al. Combined Antegrade Retrograde Cardioplegia for Myocardial Protection - a Clinical-Trial. J Thorac Cardiov Sur. 1989; 98: 956-960.

Nakao M, Morita K, Shinohara G, et al. Superior restoration of left ventricular performance after prolonged single-dose del Nido cardioplegia in conjunction with terminal warm blood cardioplegic reperfusion. J Thorac Cardiov Sur. 2022; 164: E143-+.

Ahmed AA, Mahboobi SK. Warm Blood Cardioplegia. In: StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Sohail Mahboobi declares no relevant financial relationships with ineligible companies.; 2025.

Waldenstrom J. Cardioprotective effects of increased myocardial glycogen stores and beta-blockers in cardiac surgery. Ups J Med Sci. 1983; 88: 213-219.

Turk T, Ata Y, Vural AH. [The effect of glutamate and aspartate on myocardial protection at cardiopulmonary bypass]. Anadolu Kardiyol Derg. 2004; 4: 272; author reply 272.

Lassnigg A, Punz A, Barker R, et al. Influence of intravenous vitamin E supplementation in cardiac surgery on oxidative stress: a double-blinded, randomized, controlled study. Br J Anaesth. 2003; 90: 148-154.

Yaliniz H, Tokcan A, Zeren H, et al. Effects on reperfusion injury of adding diltiazem to tepid blood cardioplegia. Heart Surgery Forum. 2004; 7: E434-E439.

Schulz R, Kelm M, Heusch G. Nitric oxide in myocardial ischemia/reperfusion injury. Cardiovasc Res. 2004; 61: 402-413.

Zeng J, He W, Qu Z, et al. Cold blood versus crystalloid cardioplegia for myocardial protection in adult cardiac surgery: a meta-analysis of randomized controlled studies. J Cardiothorac Vasc Anesth. 2014; 28: 674-681.

Fedosova M, Kimose HH, Greisen JR, et al. Blood cardioplegia benefits only patients with a long cross-clamp time. Perfusion. 2019; 34: 42-49.

Kim WK, Kim JB. The use of del Nido cardioplegia for multiple cardiac surgery in adults. J Thorac Dis. 2018; 10: S3902-S3903.

George G, Varsha AV, Philip MA, et al. Myocardial protection in cardiac surgery: Del Nido versus blood cardioplegia. Ann Card Anaesth. 2020; 23: 477-484.

Ak K, Dericioglu O, Midi A, et al. Comparison of Bretschneider HTK and Blood Cardioplegia (4:1): A Prospective Randomized Study. Thorac Cardiovasc Surg. 2024; 72: 11-20.

Lomivorotov VV, Efremov SM, Kirov MY, et al. Low-Cardiac-Output Syndrome After Cardiac Surgery. J Cardiothorac Vasc Anesth. 2017; 31: 291-308.

Boyette LC, Manna B. Physiology, Myocardial Oxygen Demand. In: StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Biagio Manna declares no relevant financial relationships with ineligible companies.; 2025.

Korelidis G, McFadyen R, Fang CC, et al. Difficulty Weaning From Cardiopulmonary Bypass Following an Aortic Valve Replacement. Cureus. 2023; 15: e42692.

Timoteo AT, Nogueira MA, Rosa SA, et al. Role of intra-aortic balloon pump counterpulsation in the treatment of acute myocardial infarction complicated by cardiogenic shock: Evidence from the Portuguese nationwide registry. Eur Heart J Acute Cardiovasc Care. 2016; 5: 23-31.

Park SJ, Kim JB, Jung SH, et al. Outcomes of extracorporeal life support for low cardiac output syndrome after major cardiac surgery. J Thorac Cardiovasc Surg. 2014; 147: 283-289.

Durandy Y. Pediatric myocardial protection. Curr Opin Cardiol. 2008; 23: 85-90.