Ovaryumun Anatomisi, Foliküllerin Histopatolojisi ve Oogenezis

Kim YH, Kim HS, Hong IS. Advances in biomaterials-based tissue engineering for regeneration of female reproductive tissues. Biofabrication. 2025;17(2), doi:10.1088/1758-5090/adae38

Gibson E, Mahdy H. Anatomy, Abdomen and Pelvis, Ovary. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025. http://www.ncbi.nlm.nih.gov/books/NBK545187/

Al-Suhaimi EA, Khan FA, Homeida AM. Regulation of Male and Female Reproductive Functions. In: Al-Suhaimi EA, editor. Emerging Concepts in Endocrine Structure and Functions. Singapore: Springer Nature, Singapore; 2022. p. 287–347. doi: 10.1007/978-981-16-9016-7_9

Hawkins SM, Matzuk MM. The Menstrual Cycle: Basic Biology. Annals of the New York Academy of Sciences. 2008;1135(1):10–8. doi:10.1196/annals.1429.018

Strauss JF, Williams CJ. Ovarian Life Cycle. In: Yen and Jaffe’s Reproductive Endocrinology. Elsevier; 2019. p.167-205.e9. https://linkinghub.elsevier.com/retrieve/pii/B9780323479127000081

Bacon RL, Niles NR. Female Reproductive System. In: Medical Histology. New York, NY: Springer New York; 1986. p. 357–93. doi:10.1007/978-1-4613-8199-0_17

Hafez B, Hafez ESE. Anatomy of Female Reproduction. In: Hafez B, Hafez ESE, editors. Reproduction in Farm Animals. 1st ed. Wiley; 2000. p. 13–29. doi:10.1002/9781119265306.ch2

Rendi MH, Muehlenbachs A, Garcia RL, Boyd KL. 17 - Female Reproductive System. In: Treuting PM, Dintzis SM, editors. Comparative Anatomy and Histology. San Diego: Academic Press; 2012. p. 253–84. doi: 10.1016/B978-0-12-381361-9.00017-2

Gökalp S, Cıncık M. Kadın Genital Sistem, Kuruş M (Ed.), Histoloji, Hücre, Doku, Sistemler, Teknikler-Moleküller-Laboratuvar-Klinik Yönleriyle Yaklaşımlar. Ankara: Akademisyen Kitabevi; 2020. p. 941-988.

Mescher AL. Junqueira Basic Histology Text and Atlas. (14th Edition). USA: McGraw-Hill; 2019.

Ross MH, Pawlina W. Histoloji Konu Anlatımı ve Atlas. (Baykal B, Çev. Ed.). Ankara: Palme Yayınevi; 2017.

Kierszenbaum AL, Tres LL. Histology and cell biology: an introduction to pathology. (Fifth edition). Philadelphia, PA: Elsevier; 2020.

Kumar, V., Abbas, A., Aster, J. Robbıns Temel Patoloji. (Tuzlalı S, Güllüoğlu M, Çevikbaş, U. Çev. Ed.). Philadelphia, PA, USA: Elsevier Limited Nobel Tıp Kitapevleri; 2020.

Krajnik K, Mietkiewska K, Skowronska A, Kordowitzki P, Skowronski MT. Oogenesis in Women: From Molecular Regulatory Pathways and Maternal Age to Stem Cells. IJMS. 2023 Apr 6;24(7):6837. doi:10.3390/ ijms24076837

Sánchez F, Smitz J. Molecular control of oogenesis. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2012;1822(12):1896–912. doi: 10.1016/j.bbadis.2012.05.013

Virant-Klun I. Postnatal oogenesis in humans: a review of recent findings. SCCAA. 2015;20(8):49-60. doi: 10.2147/SCCAA.S32650

Sadler, T.W. Langman’s Medical Embryology. Philadelphia: Wolters Kluwer; 2019.

Pepling ME. From primordial germ cell to primordial follicle: mammalian female germ cell development. genesis. 2006;44(12):622–32. doi: 10.1002/dvg.20258

Moore, K.L., Persaud, T.V.N., Torchia, M.G. The Developing Human Clinically Oriented Embryology, Philadelphia: Elsevier; 2016.

Ma L, Shen W, Zhang J. The Life Cycle of the Ovary. In: Wang S, editor. Ovarian Aging. Singapore: Springer Nature Singapore; 2023. p. 7–33. doi: 10.1007/978-981-19-8848-6_2

Orsi NM, Baskind NE, Cummings M. Anatomy, Development, Histology and Normal Function of the Ovary. In: Wilkinson N, editor. Pathology of the Ovary, Fallopian Tube and Peritoneum. Cham: Springer International Publishing; 2023. p. 1–33. (Essentials of Diagnostic Gynecological Pathology). doi: 10.1007/978-3-031-39659-5_1

Carroll, M. Clinical Reproductive Science. UK: Wiley-Blackwell; 2018.

De Felici M, Klinger FG, Farini D, Scaldaferri ML, Iona S, Lobascio M. Establishment of oocyte population in the fetal ovary: primordial germ cell proliferation and oocyte programmed cell death. Reproductive BioMedicine Online. 2005;10(2):182–91. https://www.rbmojournal.com/article/S1472-6483(10)60939-X/pdf

Picton HM. Activation of follicle development: the primordial follicle. Theriogenology. 2001;55(6):1193–210. doi: 10.1016/S0093-691X(01)00478-2

Colvin CW, Abdullatif H. Anatomy of female puberty: The clinical relevance of developmental changes in the reproductive system. Clinical Anatomy. 2013;26(1):115–29. doi: 10.1002/ca.22164

Falcone T, Hurd W.W. Clinical Reproductive Medicine and Surgery: A Practical Guide. Springer; 2017.

Stephenson, S., Dmitrieva, J. Obstetrics and Gynecology (Lippincott Connect). Walters Kluwer; 2022.

Li H, Chian RC. Follicular Development and Oocyte Growth. In: Chian RC, Nargund G, Huang JYJ, editors. Development of In Vitro Maturation for Human Oocytes. Cham: Springer International Publishing; 2017. p. 37–57. doi:10.1007/978-3-319-53454-1_2

He M, Zhang T, Yang Y, Wang C. Mechanisms of Oocyte Maturation and Related Epigenetic Regulation. Front Cell Dev Biol. 2021 Mar 19;9:654028. doi: 10.3389/fcell.2021.654028

Shu C, Yu Y, Xiaopan Chen, Guo J, Zhou Y, Wu D, et al. Three-dimensional architecture of granulosa cell derived from oocyte cumulus complex, revealed by FIB-SEM. J Ovarian Res. 2023;16(1):213. doi: 10.1186/s13048-023-01298-9

Turathum B, Gao EM, Chian RC. The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization. Cells. 2021 Sep 2;10(9):2292. doi: 10.3390/cells10092292

Xie J, Xu X, Liu S. Intercellular communication in the cumulus–oocyte complex during folliculogenesis: A review. Front Cell Dev Biol. 2023;11:1087612. doi: 10.3389/fcell.2023.1087612

Park SU, Walsh L, Berkowitz KM. Mechanisms of ovarian aging. Reproduction. 2021;162(2):R19–33. doi: 10.1530/REP-21-0022

Vollenhoven B, Hunt S. Ovarian ageing and the impact on female fertility. F1000Research 2018;22(7):1835. doi:10.12688/f1000research.16509.1

Kirkendoll SD, Bacha D. Histology, Corpus Albicans. In: StatPearls. Treasure Island (FL): StatPearls Publishing; last update 2023. http://www.ncbi.nlm.nih.gov/books/NBK545270/

Chrousos GP, Torpy DJ, Gold PW. Interactions between the Hypothalamic-Pituitary-Adrenal Axis and the Female Reproductive System: Clinical Implications. Ann Intern Med. 1998;129(3):229–40. doi:10.7326/0003-4819-129-3-199808010-00012

Messinis IE. Ovarian feedback, mechanism of action and possible clinical implications. Human Reproduction Update. 2006 Sep 1;12(5):557–71. doi: 10.1093/humupd/dml020

Shaw ND, Histed SN, Srouji SS, Yang J, Lee H, Hall JE. Estrogen Negative Feedback on Gonadotropin Secretion: Evidence for a Direct Pituitary Effect in Women. The Journal of Clinical Endocrinology & Metabolism. 2010;95(4):1955–61. doi: 10.1210/jc.2009-2108

Welt CK, Pagan YL, Smith PC, Rado KB, Hall JE. Control of Follicle-Stimulating Hormone by Estradiol and the Inhibins: Critical Role of Estradiol at the Hypothalamus during the Luteal-Follicular Transition. The Journal of Clinical Endocrinology&Metabolism. 2003;88(4):1766–71. doi: 10.1210/jc.2002-021516

Butler L, Santoro N. The reproductive endocrinology of the menopausal transition. Steroids. 2011;76(7):627–35. doi: 10.1016/j.steroids.2011.02.026

Santoro N, Epperson CN, Mathews SB. Menopausal Symptoms and Their Management. Endocrinology and Metabolism Clinics of North America. 2015 Sep;44(3):497–515. doi:10.1016/j.ecl.2015.05.001

Vogt EC, Russell HNB, Øksnes M, Lund A. Prematur ovarialinsuffisiens. Tidsskriftet. 2022. https://tidsskriftet.no/2022/07/klinisk-oversikt/prematur-ovarialinsuffisiens

Santoro N, Roeca C, Peters BA, Neal-Perry G. The Menopause Transition: Signs, Symptoms, and Management Options. The Journal of Clinical Endocrinology & Metabolism. 2021;106(1):1–15. doi: 10.1210/clinem/dgaa764

Kim YH, Kim HS, Hong IS. Advances in biomaterials-based tissue engineering for regeneration of female reproductive tissues. Biofabrication. 2025;17(2), doi:10.1088/1758-5090/adae38

Gibson E, Mahdy H. Anatomy, Abdomen and Pelvis, Ovary. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025. http://www.ncbi.nlm.nih.gov/books/NBK545187/

Al-Suhaimi EA, Khan FA, Homeida AM. Regulation of Male and Female Reproductive Functions. In: Al-Suhaimi EA, editor. Emerging Concepts in Endocrine Structure and Functions. Singapore: Springer Nature, Singapore; 2022. p. 287–347. doi: 10.1007/978-981-16-9016-7_9

Hawkins SM, Matzuk MM. The Menstrual Cycle: Basic Biology. Annals of the New York Academy of Sciences. 2008;1135(1):10–8. doi:10.1196/annals.1429.018

Strauss JF, Williams CJ. Ovarian Life Cycle. In: Yen and Jaffe’s Reproductive Endocrinology. Elsevier; 2019. p.167-205.e9. https://linkinghub.elsevier.com/retrieve/pii/B9780323479127000081

Bacon RL, Niles NR. Female Reproductive System. In: Medical Histology. New York, NY: Springer New York; 1986. p. 357–93. doi:10.1007/978-1-4613-8199-0_17

Hafez B, Hafez ESE. Anatomy of Female Reproduction. In: Hafez B, Hafez ESE, editors. Reproduction in Farm Animals. 1st ed. Wiley; 2000. p. 13–29. doi:10.1002/9781119265306.ch2

Rendi MH, Muehlenbachs A, Garcia RL, Boyd KL. 17 - Female Reproductive System. In: Treuting PM, Dintzis SM, editors. Comparative Anatomy and Histology. San Diego: Academic Press; 2012. p. 253–84. doi: 10.1016/B978-0-12-381361-9.00017-2

Gökalp S, Cıncık M. Kadın Genital Sistem, Kuruş M (Ed.), Histoloji, Hücre, Doku, Sistemler, Teknikler-Moleküller-Laboratuvar-Klinik Yönleriyle Yaklaşımlar. Ankara: Akademisyen Kitabevi; 2020. p. 941-988.

Mescher AL. Junqueira Basic Histology Text and Atlas. (14th Edition). USA: McGraw-Hill; 2019.

Ross MH, Pawlina W. Histoloji Konu Anlatımı ve Atlas. (Baykal B, Çev. Ed.). Ankara: Palme Yayınevi; 2017.

Kierszenbaum AL, Tres LL. Histology and cell biology: an introduction to pathology. (Fifth edition). Philadelphia, PA: Elsevier; 2020.

Kumar, V., Abbas, A., Aster, J. Robbıns Temel Patoloji. (Tuzlalı S, Güllüoğlu M, Çevikbaş, U. Çev. Ed.). Philadelphia, PA, USA: Elsevier Limited Nobel Tıp Kitapevleri; 2020.

Krajnik K, Mietkiewska K, Skowronska A, Kordowitzki P, Skowronski MT. Oogenesis in Women: From Molecular Regulatory Pathways and Maternal Age to Stem Cells. IJMS. 2023 Apr 6;24(7):6837. doi:10.3390/ ijms24076837

Sánchez F, Smitz J. Molecular control of oogenesis. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2012;1822(12):1896–912. doi: 10.1016/j.bbadis.2012.05.013

Virant-Klun I. Postnatal oogenesis in humans: a review of recent findings. SCCAA. 2015;20(8):49-60. doi: 10.2147/SCCAA.S32650

Sadler, T.W. Langman’s Medical Embryology. Philadelphia: Wolters Kluwer; 2019.

Pepling ME. From primordial germ cell to primordial follicle: mammalian female germ cell development. genesis. 2006;44(12):622–32. doi: 10.1002/dvg.20258

Moore, K.L., Persaud, T.V.N., Torchia, M.G. The Developing Human Clinically Oriented Embryology, Philadelphia: Elsevier; 2016.

Ma L, Shen W, Zhang J. The Life Cycle of the Ovary. In: Wang S, editor. Ovarian Aging. Singapore: Springer Nature Singapore; 2023. p. 7–33. doi: 10.1007/978-981-19-8848-6_2

Orsi NM, Baskind NE, Cummings M. Anatomy, Development, Histology and Normal Function of the Ovary. In: Wilkinson N, editor. Pathology of the Ovary, Fallopian Tube and Peritoneum. Cham: Springer International Publishing; 2023. p. 1–33. (Essentials of Diagnostic Gynecological Pathology). doi: 10.1007/978-3-031-39659-5_1

Carroll, M. Clinical Reproductive Science. UK: Wiley-Blackwell; 2018.

De Felici M, Klinger FG, Farini D, Scaldaferri ML, Iona S, Lobascio M. Establishment of oocyte population in the fetal ovary: primordial germ cell proliferation and oocyte programmed cell death. Reproductive BioMedicine Online. 2005;10(2):182–91. https://www.rbmojournal.com/article/S1472-6483(10)60939-X/pdf

Picton HM. Activation of follicle development: the primordial follicle. Theriogenology. 2001;55(6):1193–210. doi: 10.1016/S0093-691X(01)00478-2

Colvin CW, Abdullatif H. Anatomy of female puberty: The clinical relevance of developmental changes in the reproductive system. Clinical Anatomy. 2013;26(1):115–29. doi: 10.1002/ca.22164

Falcone T, Hurd W.W. Clinical Reproductive Medicine and Surgery: A Practical Guide. Springer; 2017.

Stephenson, S., Dmitrieva, J. Obstetrics and Gynecology (Lippincott Connect). Walters Kluwer; 2022.

Li H, Chian RC. Follicular Development and Oocyte Growth. In: Chian RC, Nargund G, Huang JYJ, editors. Development of In Vitro Maturation for Human Oocytes. Cham: Springer International Publishing; 2017. p. 37–57. doi:10.1007/978-3-319-53454-1_2

He M, Zhang T, Yang Y, Wang C. Mechanisms of Oocyte Maturation and Related Epigenetic Regulation. Front Cell Dev Biol. 2021 Mar 19;9:654028. doi: 10.3389/fcell.2021.654028

Shu C, Yu Y, Xiaopan Chen, Guo J, Zhou Y, Wu D, et al. Three-dimensional architecture of granulosa cell derived from oocyte cumulus complex, revealed by FIB-SEM. J Ovarian Res. 2023;16(1):213. doi: 10.1186/s13048-023-01298-9

Turathum B, Gao EM, Chian RC. The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization. Cells. 2021 Sep 2;10(9):2292. doi: 10.3390/cells10092292

Xie J, Xu X, Liu S. Intercellular communication in the cumulus–oocyte complex during folliculogenesis: A review. Front Cell Dev Biol. 2023;11:1087612. doi: 10.3389/fcell.2023.1087612

Park SU, Walsh L, Berkowitz KM. Mechanisms of ovarian aging. Reproduction. 2021;162(2):R19–33. doi: 10.1530/REP-21-0022

Vollenhoven B, Hunt S. Ovarian ageing and the impact on female fertility. F1000Research 2018;22(7):1835. doi:10.12688/f1000research.16509.1

Kirkendoll SD, Bacha D. Histology, Corpus Albicans. In: StatPearls. Treasure Island (FL): StatPearls Publishing; last update 2023. http://www.ncbi.nlm.nih.gov/books/NBK545270/

Chrousos GP, Torpy DJ, Gold PW. Interactions between the Hypothalamic-Pituitary-Adrenal Axis and the Female Reproductive System: Clinical Implications. Ann Intern Med. 1998;129(3):229–40. doi:10.7326/0003-4819-129-3-199808010-00012

Messinis IE. Ovarian feedback, mechanism of action and possible clinical implications. Human Reproduction Update. 2006 Sep 1;12(5):557–71. doi: 10.1093/humupd/dml020

Shaw ND, Histed SN, Srouji SS, Yang J, Lee H, Hall JE. Estrogen Negative Feedback on Gonadotropin Secretion: Evidence for a Direct Pituitary Effect in Women. The Journal of Clinical Endocrinology & Metabolism. 2010;95(4):1955–61. doi: 10.1210/jc.2009-2108

Welt CK, Pagan YL, Smith PC, Rado KB, Hall JE. Control of Follicle-Stimulating Hormone by Estradiol and the Inhibins: Critical Role of Estradiol at the Hypothalamus during the Luteal-Follicular Transition. The Journal of Clinical Endocrinology&Metabolism. 2003;88(4):1766–71. doi: 10.1210/jc.2002-021516

Butler L, Santoro N. The reproductive endocrinology of the menopausal transition. Steroids. 2011;76(7):627–35. doi: 10.1016/j.steroids.2011.02.026

Santoro N, Epperson CN, Mathews SB. Menopausal Symptoms and Their Management. Endocrinology and Metabolism Clinics of North America. 2015 Sep;44(3):497–515. doi:10.1016/j.ecl.2015.05.001

Vogt EC, Russell HNB, Øksnes M, Lund A. Prematur ovarialinsuffisiens. Tidsskriftet. 2022. https://tidsskriftet.no/2022/07/klinisk-oversikt/prematur-ovarialinsuffisiens

Santoro N, Roeca C, Peters BA, Neal-Perry G. The Menopause Transition: Signs, Symptoms, and Management Options. The Journal of Clinical Endocrinology & Metabolism. 2021;106(1):1–15. doi: 10.1210/clinem/dgaa764