IVF Embriyoloji, Androloji Laboratuvarında Kalite Kontrol Nasıl Yapılmalı ?

Fabozzi G, Cimadomo D, Maggiulli R, Vaiarelli A, Ubaldi FM, Rienzi L. Which key performance indicators are most effective in evaluating and managing an in vitro fertilization laboratory? Fertility and Sterility. 2020 Jul;114(1):9–15.

Alikani M, Campbell A. Shaping the future of the IVF laboratory: standardization for more predictable outcomes. Reprod Biomed Online. 2025 Apr;50(4):104854.

Wang J, Sauer MV. In vitro fertilization (IVF): a review of 3 decades of clinical innovation and technological advancement. Ther Clin Risk Manag. 2006 Dec;2(4):355–64.

Consensus Group C. “There is only one thing that is truly important in an IVF laboratory: everything” Cairo Consensus Guidelines on IVF Culture Conditions. Reprod Biomed Online. 2020 Jan;40(1):33–60.

Mortimer D, Cohen J, Mortimer ST, Fawzy M, McCulloh DH, Morbeck DE, et al. Cairo consensus on the IVF laboratory environment and air quality: report of an expert meeting. Reprod Biomed Online. 2018 Jun;36(6):658–74.

Esteves S, Bento F. Air quality control in the ART laboratory is a major determinant of IVF success. Asian J Androl. 2016;18(4):596.

Morbeck DE. Air quality in the assisted reproduction laboratory: a mini-review. J Assist Reprod Genet. 2015 Jul;32(7):1019–24.

Sciorio R, Rapalini E, Esteves SC. Air quality in the clinical embryology laboratory: a mini-review. Ther Adv Reprod Health. 2021;15:1–11.

Esteves SC, Bento FC. Implementation of cleanroom technology in reproductive laboratories: the question is not why but how. Reproductive BioMedicine Online. 2016 Jan;32(1):9–11.

Heitmann RJ, Hill MJ, James AN, Schimmel T, Segars JH, Csokmay JM, et al. Live births achieved via IVF are increased by improvements in air quality and laboratory environment. Reproductive BioMedicine Online. 2015 Sep;31(3):364–71.

Korakaki D, Mouroutsos S, Tripsianis G, Nikolettos N, Asimakopoulos B. Temperature Decline in Embryological Culture Dishes outside Incubator. Int J Fertil Steril. 2020 Apr;14(1):63–7.

Swain JE. Controversies in ART: can the IVF laboratory influence preimplantation embryo aneuploidy? Reprod Biomed Online. 2019 Oct;39(4):599–607.

Mestres E, García-Jiménez M, Casals A, Cohen J, Acacio M, Villamar A, et al. Factors of the human embryo culture system that may affect media evaporation and osmolality. Hum Reprod. 2021 Feb 18;36(3):605–13.

Delaroche L, Oger P, Genauzeau E, Meicler P, Lamazou F, Dupont C, et al. Embryotoxicity testing of IVF disposables: how do manufacturers test? Hum Reprod. 2020 Feb 29;35(2):283–92.

Delaroche L, Besnard L, Ouary V, Bazin F, Cassuto G. Disposables used cumulatively in routine IVF procedures could display toxicity. Hum Reprod. 2024 May 2;39(5):936–54.

Antonouli S, Di Nisio V, Messini C, Daponte A, Rajender S, Anifandis G. A comprehensive review and update on human fertility cryopreservation methods and tools. Front Vet Sci [Internet]. 2023 Apr 18 [cited 2025 Jul 15];10.

Canosa S, Maggiulli R, Cimadomo D, Innocenti F, Fabozzi G, Gennarelli G, et al. Cryostorage management of reproductive cells and tissues in ART: status, needs, opportunities and potential new challenges. Reprod Biomed Online. 2023 Sep;47(3):103252.

ESHRE Special Interest Group of Embryology, Alpha Scientists in Reproductive Medicine. The Vienna consensus: report of an expert meeting on the development of art laboratory performance indicators†‡. Human Reproduction Open [Internet]. 2017 Aug 4 [cited 2025 Jul 14];2017(2).

Vaiarelli A, Zacà C, Spadoni V, Cimadomo D, Conforti A, Alviggi C, et al. Clinical and laboratory key performance indicators in IVF: A consensus between the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) and the Italian Society of Embryology, Reproduction and Research (SIERR). J Assist Reprod Genet. 2023 Jun;40(6):1479–94.

ESHRE Guideline Group on Good Practice in IVF Labs, De los Santos MJ, Apter S, Coticchio G, Debrock S, Lundin K, et al. Revised guidelines for good practice in IVF laboratories (2015). Hum Reprod. 2016 Apr;31(4):685–6.

Manghani K. Quality assurance: Importance of systems and standard operating procedures. Perspect Clin Res. 2011;2(1):34.

Knudtson JF, Robinson RD, Sparks AE, Hill MJ, Chang TA, Van Voorhis BJ. Common practices among consistently high-performing in vitro fertilization programs in the United States: 10-year update. Fertility and Sterility. 2022 Jan;117(1):42–50.

Jayamani J, Janardan CC, Appan SV, Kathamuthu K, Ahmed ME. A Practical Tool for Risk Management in Clinical Laboratories. Cureus [Internet]. 2022 Dec 21 [cited 2025 Jul 15]

Cairo Consensus Group, Alpha Scientists In Reproductive Medicine. Cairo Consensus on Accreditation as the Basis for Future-Proofing the ART Laboratory. Reproductive BioMedicine Online. 2025 Jan;50(1):104106.

Fabozzi G, Cimadomo D, Maggiulli R, Vaiarelli A, Ubaldi FM, Rienzi L. Which key performance indicators are most effective in evaluating and managing an in vitro fertilization laboratory? Fertility and Sterility. 2020 Jul;114(1):9–15.

Alikani M, Campbell A. Shaping the future of the IVF laboratory: standardization for more predictable outcomes. Reprod Biomed Online. 2025 Apr;50(4):104854.

Wang J, Sauer MV. In vitro fertilization (IVF): a review of 3 decades of clinical innovation and technological advancement. Ther Clin Risk Manag. 2006 Dec;2(4):355–64.

Consensus Group C. “There is only one thing that is truly important in an IVF laboratory: everything” Cairo Consensus Guidelines on IVF Culture Conditions. Reprod Biomed Online. 2020 Jan;40(1):33–60.

Mortimer D, Cohen J, Mortimer ST, Fawzy M, McCulloh DH, Morbeck DE, et al. Cairo consensus on the IVF laboratory environment and air quality: report of an expert meeting. Reprod Biomed Online. 2018 Jun;36(6):658–74.

Esteves S, Bento F. Air quality control in the ART laboratory is a major determinant of IVF success. Asian J Androl. 2016;18(4):596.

Morbeck DE. Air quality in the assisted reproduction laboratory: a mini-review. J Assist Reprod Genet. 2015 Jul;32(7):1019–24.

Sciorio R, Rapalini E, Esteves SC. Air quality in the clinical embryology laboratory: a mini-review. Ther Adv Reprod Health. 2021;15:1–11.

Esteves SC, Bento FC. Implementation of cleanroom technology in reproductive laboratories: the question is not why but how. Reproductive BioMedicine Online. 2016 Jan;32(1):9–11.

Heitmann RJ, Hill MJ, James AN, Schimmel T, Segars JH, Csokmay JM, et al. Live births achieved via IVF are increased by improvements in air quality and laboratory environment. Reproductive BioMedicine Online. 2015 Sep;31(3):364–71.

Korakaki D, Mouroutsos S, Tripsianis G, Nikolettos N, Asimakopoulos B. Temperature Decline in Embryological Culture Dishes outside Incubator. Int J Fertil Steril. 2020 Apr;14(1):63–7.

Swain JE. Controversies in ART: can the IVF laboratory influence preimplantation embryo aneuploidy? Reprod Biomed Online. 2019 Oct;39(4):599–607.

Mestres E, García-Jiménez M, Casals A, Cohen J, Acacio M, Villamar A, et al. Factors of the human embryo culture system that may affect media evaporation and osmolality. Hum Reprod. 2021 Feb 18;36(3):605–13.

Delaroche L, Oger P, Genauzeau E, Meicler P, Lamazou F, Dupont C, et al. Embryotoxicity testing of IVF disposables: how do manufacturers test? Hum Reprod. 2020 Feb 29;35(2):283–92.

Delaroche L, Besnard L, Ouary V, Bazin F, Cassuto G. Disposables used cumulatively in routine IVF procedures could display toxicity. Hum Reprod. 2024 May 2;39(5):936–54.

Antonouli S, Di Nisio V, Messini C, Daponte A, Rajender S, Anifandis G. A comprehensive review and update on human fertility cryopreservation methods and tools. Front Vet Sci [Internet]. 2023 Apr 18 [cited 2025 Jul 15];10.

Canosa S, Maggiulli R, Cimadomo D, Innocenti F, Fabozzi G, Gennarelli G, et al. Cryostorage management of reproductive cells and tissues in ART: status, needs, opportunities and potential new challenges. Reprod Biomed Online. 2023 Sep;47(3):103252.

ESHRE Special Interest Group of Embryology, Alpha Scientists in Reproductive Medicine. The Vienna consensus: report of an expert meeting on the development of art laboratory performance indicators†‡. Human Reproduction Open [Internet]. 2017 Aug 4 [cited 2025 Jul 14];2017(2).

Vaiarelli A, Zacà C, Spadoni V, Cimadomo D, Conforti A, Alviggi C, et al. Clinical and laboratory key performance indicators in IVF: A consensus between the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) and the Italian Society of Embryology, Reproduction and Research (SIERR). J Assist Reprod Genet. 2023 Jun;40(6):1479–94.

ESHRE Guideline Group on Good Practice in IVF Labs, De los Santos MJ, Apter S, Coticchio G, Debrock S, Lundin K, et al. Revised guidelines for good practice in IVF laboratories (2015). Hum Reprod. 2016 Apr;31(4):685–6.

Manghani K. Quality assurance: Importance of systems and standard operating procedures. Perspect Clin Res. 2011;2(1):34.

Knudtson JF, Robinson RD, Sparks AE, Hill MJ, Chang TA, Van Voorhis BJ. Common practices among consistently high-performing in vitro fertilization programs in the United States: 10-year update. Fertility and Sterility. 2022 Jan;117(1):42–50.

Jayamani J, Janardan CC, Appan SV, Kathamuthu K, Ahmed ME. A Practical Tool for Risk Management in Clinical Laboratories. Cureus [Internet]. 2022 Dec 21 [cited 2025 Jul 15]

Cairo Consensus Group, Alpha Scientists In Reproductive Medicine. Cairo Consensus on Accreditation as the Basis for Future-Proofing the ART Laboratory. Reproductive BioMedicine Online. 2025 Jan;50(1):104106.