PCOS Tanısı ve İnfertilite Açısından Oral Ajanlarla Yönetimi

Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, et al. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Eur J Endocrinol. 2023 Aug 1;189(2):G43–64.

Tosi F, Bonora E, Moghetti P. Insulin resistance in a large cohort of women with polycystic ovary syndrome: a comparison between euglycaemic-hyperinsulinaemic clamp and surrogate indexes. Hum Reprod. 2017 Dec 1;32(12):2515–21.

Myers SH, Russo M, Dinicola S, Forte G, Unfer V. Questioning PCOS phenotypes for reclassification and tailored therapy. Trends Endocrinol Metab. 2023 Nov 1;34(11):694–703.

Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome (2023) - practice guidance [Internet]. [cited 2025 Jun 9].

Christ JP, Cedars MI. Current Guidelines for Diagnosing PCOS. Diagnostics. 2023 Jan;13(6):1113.

Starace M, Orlando G, Alessandrini A, Piraccini BM. Female Androgenetic Alopecia: An Update on Diagnosis and Management. Am J Clin Dermatol. 2020 Feb;21(1):69–84.

Wang L, Wen ,Xinqiang, Lv ,Shulan, Zhao ,Juan, Yang ,Ting, and Yang X. Comparison of endometrial receptivity of clomiphene citrate versus letrozole in women with polycystic ovary syndrome: a randomized controlled study. Gynecol Endocrinol. 2019 Oct 3;35(10):862–5.

Therapeutic approach for metabolic disorders and infertility in women with PCOS [Internet]. [cited 2025 Jun 11]. c

Casper RF. Aromatase inhibitors in ovarian stimulation. J Steroid Biochem Mol Biol. 2007 Aug 1;106(1):71–5.

Chen Z, Zhang M, Qiao Y, Yang J. Effects of letrozole in combination with low-dose intramuscular injection of human menopausal gonadotropin on ovulation and pregnancy of 156 patients with polycystic ovary syndrome. Pak J Med Sci. 2016;32(6):1434–8.

Liu Z, Geng Y, Huang Y, Hu R, Li F, Song Y, et al. Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis. Obstet Gynecol. 2023 Mar;141(3):523.

Diagnostic evaluation of the infertile female: a committee opinion. Fertil Steril. 2015 Jun 1;103(6):e44–50.

Rababa’h AM, Matani BR, Yehya A. An update of polycystic ovary syndrome: causes and therapeutics options. Heliyon [Internet]. 2022 Oct 1 [cited 2025 Jun 11];8(10).

Attia GM, Almouteri MM, Alnakhli FT, Almouteri M, Alnakhli F. Role of metformin in polycystic ovary syndrome (PCOS)-related infertility. Cureus [Internet]. 2023 [cited 2025 Jun 12];15(8).

Notaro ALG, Neto FTL. The use of metformin in women with polycystic ovary syndrome: an updated review. J Assist Reprod Genet. 2022 Mar 1;39(3):573–9.

Yazdanpanah Z, Cheraghi E, Nasrabadi MH, Salehipour M. Improvement in biochemical manifestations of the serum and follicular fluid and ICSI outcomes in PCOS patients with myo-inositol administration: prospective randomized research. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jun 1;398(6):7187–98.

Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, et al. Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10.

Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, et al. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Eur J Endocrinol. 2023 Aug 1;189(2):G43–64.

Tosi F, Bonora E, Moghetti P. Insulin resistance in a large cohort of women with polycystic ovary syndrome: a comparison between euglycaemic-hyperinsulinaemic clamp and surrogate indexes. Hum Reprod. 2017 Dec 1;32(12):2515–21.

Myers SH, Russo M, Dinicola S, Forte G, Unfer V. Questioning PCOS phenotypes for reclassification and tailored therapy. Trends Endocrinol Metab. 2023 Nov 1;34(11):694–703.

Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome (2023) - practice guidance [Internet]. [cited 2025 Jun 9].

Christ JP, Cedars MI. Current Guidelines for Diagnosing PCOS. Diagnostics. 2023 Jan;13(6):1113.

Starace M, Orlando G, Alessandrini A, Piraccini BM. Female Androgenetic Alopecia: An Update on Diagnosis and Management. Am J Clin Dermatol. 2020 Feb;21(1):69–84.

Wang L, Wen ,Xinqiang, Lv ,Shulan, Zhao ,Juan, Yang ,Ting, and Yang X. Comparison of endometrial receptivity of clomiphene citrate versus letrozole in women with polycystic ovary syndrome: a randomized controlled study. Gynecol Endocrinol. 2019 Oct 3;35(10):862–5.

Therapeutic approach for metabolic disorders and infertility in women with PCOS [Internet]. [cited 2025 Jun 11]. c

Casper RF. Aromatase inhibitors in ovarian stimulation. J Steroid Biochem Mol Biol. 2007 Aug 1;106(1):71–5.

Chen Z, Zhang M, Qiao Y, Yang J. Effects of letrozole in combination with low-dose intramuscular injection of human menopausal gonadotropin on ovulation and pregnancy of 156 patients with polycystic ovary syndrome. Pak J Med Sci. 2016;32(6):1434–8.

Liu Z, Geng Y, Huang Y, Hu R, Li F, Song Y, et al. Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis. Obstet Gynecol. 2023 Mar;141(3):523.

Diagnostic evaluation of the infertile female: a committee opinion. Fertil Steril. 2015 Jun 1;103(6):e44–50.

Rababa’h AM, Matani BR, Yehya A. An update of polycystic ovary syndrome: causes and therapeutics options. Heliyon [Internet]. 2022 Oct 1 [cited 2025 Jun 11];8(10).

Attia GM, Almouteri MM, Alnakhli FT, Almouteri M, Alnakhli F. Role of metformin in polycystic ovary syndrome (PCOS)-related infertility. Cureus [Internet]. 2023 [cited 2025 Jun 12];15(8).

Notaro ALG, Neto FTL. The use of metformin in women with polycystic ovary syndrome: an updated review. J Assist Reprod Genet. 2022 Mar 1;39(3):573–9.

Yazdanpanah Z, Cheraghi E, Nasrabadi MH, Salehipour M. Improvement in biochemical manifestations of the serum and follicular fluid and ICSI outcomes in PCOS patients with myo-inositol administration: prospective randomized research. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jun 1;398(6):7187–98.

Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, et al. Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10.