Hipotalamustan Salgılanan Hormonlar

Braak H, Braak E. Anatomy of the human hypothalamus (chiasmatic and tuberal region). Prog Brain Res. 1992;93:3-14; discussion -6.

Kelberman D, Dattani MT. Role of transcription factors in midline central nervous system and pituitary defects. Endocr Dev. 2009;14:67-82.

Seeburg PH, Mason AJ, Stewart TA, et al. The mammalian GnRH gene and its pivotal role in reproduction. Recent Prog Horm Res. 1987;43:69-98.

Millar RP. GnRHs and GnRH receptors. Anim Reprod Sci. 2005;88(1-2):5-28.

Maggi R, Cariboni AM, Marelli MM, et al. GnRH and GnRH receptors in the pathophysiology of the human female reproductive system. Hum Reprod Update. 2016;22(3):358-381.

Leung PC, Cheng CK, Zhu XM. Multi-factorial role of GnRH-I and GnRH-II in the human ovary. Mol Cell Endocrinol. 2003;202(1-2):145-153.

Sower SA, Chiang YC, Lovas S, et al. Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brain. Endocrinology. 1993;132(3):1125-1131.

Kovacs M, Seprodi J, Koppan M, et al. Lamprey gonadotropin hormone-releasing hormone-III has no selective follicle-stimulating hormone-releasing effect in rats. J Neuroendocrinol. 2002;14(8):647-655.

Fan NC, Jeung EB, Peng C, et al. The human gonadotropin-releasing hormone (GnRH) receptor gene: cloning, genomic organization and chromosomal assignment. Mol Cell Endocrinol. 1994;103(1-2):R1-6.

Kraus S, Naor Z, Seger R. Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor. Arch Med Res. 2001;32(6):499-509.

Kaiser UB, Conn PM, Chin WW. Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines. Endocr Rev. 1997;18(1):46-70.

Plant TM. Neuroendocrine control of the onset of puberty. Front Neuroendocrinol. 2015;38:73-88.

Skorupskaite K, George JT, Anderson RA. The kisspeptin-GnRH pathway in human reproductive health and disease. Hum Reprod Update. 2014;20(4):485-500.

DePaolo LV, King RA, Carrillo AJ. In vivo and in vitro examination of an autoregulatory mechanism for luteinizing hormone-releasing hormone. Endocrinology. 1987;120(1):272-279.

Zimmer CA, Ehrmann DA, Rosenfield RL. Potential diagnostic utility of intermittent administration of short-acting gonadotropin-releasing hormone agonist in gonadotropin deficiency. Fertil Steril. 2010;94(7):2697-2702.

Blumenfeld Z. Endocrine prevention of chemotherapy-induced ovarian failure. Future Oncol. 2016;12(14):1671-1674.

Blumenfeld Z, Evron A. Preserving fertility when choosing chemotherapy regimens - the role of gonadotropin-releasing hormone agonists. Expert Opin Pharmacother. 2015;16(7):1009-1020.

Engel JB, Schally AV. Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone. Nat Clin Pract Endocrinol Metab. 2007;3(2):157-167.

Limonta P, Montagnani Marelli M, Mai S, et al. GnRH receptors in cancer: from cell biology to novel targeted therapeutic strategies. Endocr Rev. 2012;33(5):784-811.

Tan O, Bukulmez O. Biochemistry, molecular biology and cell biology of gonadotropin-releasing hormone antagonists. Curr Opin Obstet Gynecol. 2011;23(4):238-244.

Jackson IM. Thyrotropin-releasing hormone. N Engl J Med. 1982;306(3):145-155.

Magner JA. Thyroid-stimulating hormone: biosynthesis, cell biology, and bioactivity. Endocr Rev. 1990;11(2):354-385.

Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol. 2004;44:525-557.

Black PH. Stress and the inflammatory response: a review of neurogenic inflammation. Brain Behav Immun. 2002;16(6):622-653.

Matsoukas MT, Spyroulias GA. Dynamic properties of the growth hormone releasing hormone receptor (GHRHR) and molecular determinants of GHRH binding. Mol Biosyst. 2017;13(7):1313-1322.

Freeman ME, Kanyicska B, Lerant A, et al. Prolactin: structure, function, and regulation of secretion. Physiol Rev. 2000;80(4):1523-1631.

Schultz W. Updating dopamine reward signals. Curr Opin Neurobiol. 2013;23(2):229-238.

Stueven AK, Kayser A, Wetz C, et al. Somatostatin Analogues in the Treatment of Neuroendocrine Tumors: Past, Present and Future. Int J Mol Sci. 2019;20(12).

Ampofo E, Nalbach L, Menger MD, et al. Regulatory Mechanisms of Somatostatin Expression. Int J Mol Sci. 2020;21(11).

Gomes-Porras M, Cárdenas-Salas J, Álvarez-Escolá C. Somatostatin Analogs in Clinical Practice: a Review. Int J Mol Sci. 2020;21(5).

Rogoza O, Megnis K, Kudrjavceva M, et al. Role of Somatostatin Signalling in Neuroendocrine Tumours. Int J Mol Sci. 2022;23(3).

Gábriel R. Neuropeptides and diabetic retinopathy. Br J Clin Pharmacol. 2013;75(5):1189-1201.

Perkinson MR, Kim JS, Iremonger KJ, et al. Visualising oxytocin neurone activity in vivo: The key to unlocking central regulation of parturition and lactation. J Neuroendocrinol. 2021;33(11):e13012.

Ellis JA, Brown CM, Barger B, et al. Influence of Maternal Obesity on Labor Induction: A Systematic Review and Meta-Analysis. J Midwifery Womens Health. 2019;64(1):55-67.

Birnbaumer M. Vasopressin receptors. Trends Endocrinol Metab. 2000;11(10):406-410.

Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. 2017;43(3):304-377.

Ceccatelli S, Eriksson M, Hökfelt T. Distribution and coexistence of corticotropin-releasing factor-, neurotensin-, enkephalin-, cholecystokinin-, galanin- and vasoactive intestinal polypeptide/peptide histidine isoleucine-like peptides in the parvocellular part of the paraventricular nucleus. Neuroendocrinology. 1989;49(3):309-323.

Rostène WH. Neurobiological and neuroendocrine functions of the vasoactive intestinal peptide (VIP). Prog Neurobiol. 1984;22(2):103-129.

Sarkar DK. Evidence for prolactin feedback actions on hypothalamic oxytocin, vasoactive intestinal peptide and dopamine secretion. Neuroendocrinology. 1989;49(5):520-524.

Lam KS, Srivastava G, Lechan RM, et al. Estrogen regulates the gene expression of vasoactive intestinal peptide in the anterior pituitary. Neuroendocrinology. 1990;52(5):417-421.

Bardrum B, Ottesen B, Fahrenkrug J, et al. Release of oxytocin and vasopressin by intracerebroventricular vasoactive intestinal polypeptide. Endocrinology. 1988;123(5):2249-2254.

West A, Vojta PJ, Welch DR, et al. Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1). Genomics. 1998;54(1):145-148.

Pinilla L, Aguilar E, Dieguez C, et al. Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiol Rev. 2012;92(3):1235-1316.

Jiang Y, Berk M, Singh LS, et al. KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metastasis. 2005;22(5):369-376.

Tomikawa J, Uenoyama Y, Ozawa M, et al. Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain. Proc Natl Acad Sci U S A. 2012;109(20):E1294-1301.

Watanabe Y, Uenoyama Y, Suzuki J, et al. Oestrogen-induced activation of preoptic kisspeptin neurones may be involved in the luteinising hormone surge in male and female Japanese monkeys. J Neuroendocrinol. 2014;26(12):909-917.

Rance NE. Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback. Peptides. 2009;30(1):111-122.

Abbara A, Eng PC, Phylactou M, et al. Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders. J Clin Invest. 2020;130(12):6739-6753.

Hoskova K, Kayton Bryant N, Chen ME, et al. Kisspeptin Overcomes GnRH Neuronal Suppression Secondary to Hyperprolactinemia in Humans. J Clin Endocrinol Metab. 2022;107(8):e3515-e3525.

Ishikawa K, Tanaka A, Kogame A, et al. Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model. Eur J Pharmacol. 2018;828:126-134.

Braak H, Braak E. Anatomy of the human hypothalamus (chiasmatic and tuberal region). Prog Brain Res. 1992;93:3-14; discussion -6.

Kelberman D, Dattani MT. Role of transcription factors in midline central nervous system and pituitary defects. Endocr Dev. 2009;14:67-82.

Seeburg PH, Mason AJ, Stewart TA, et al. The mammalian GnRH gene and its pivotal role in reproduction. Recent Prog Horm Res. 1987;43:69-98.

Millar RP. GnRHs and GnRH receptors. Anim Reprod Sci. 2005;88(1-2):5-28.

Maggi R, Cariboni AM, Marelli MM, et al. GnRH and GnRH receptors in the pathophysiology of the human female reproductive system. Hum Reprod Update. 2016;22(3):358-381.

Leung PC, Cheng CK, Zhu XM. Multi-factorial role of GnRH-I and GnRH-II in the human ovary. Mol Cell Endocrinol. 2003;202(1-2):145-153.

Sower SA, Chiang YC, Lovas S, et al. Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brain. Endocrinology. 1993;132(3):1125-1131.

Kovacs M, Seprodi J, Koppan M, et al. Lamprey gonadotropin hormone-releasing hormone-III has no selective follicle-stimulating hormone-releasing effect in rats. J Neuroendocrinol. 2002;14(8):647-655.

Fan NC, Jeung EB, Peng C, et al. The human gonadotropin-releasing hormone (GnRH) receptor gene: cloning, genomic organization and chromosomal assignment. Mol Cell Endocrinol. 1994;103(1-2):R1-6.

Kraus S, Naor Z, Seger R. Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor. Arch Med Res. 2001;32(6):499-509.

Kaiser UB, Conn PM, Chin WW. Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines. Endocr Rev. 1997;18(1):46-70.

Plant TM. Neuroendocrine control of the onset of puberty. Front Neuroendocrinol. 2015;38:73-88.

Skorupskaite K, George JT, Anderson RA. The kisspeptin-GnRH pathway in human reproductive health and disease. Hum Reprod Update. 2014;20(4):485-500.

DePaolo LV, King RA, Carrillo AJ. In vivo and in vitro examination of an autoregulatory mechanism for luteinizing hormone-releasing hormone. Endocrinology. 1987;120(1):272-279.

Zimmer CA, Ehrmann DA, Rosenfield RL. Potential diagnostic utility of intermittent administration of short-acting gonadotropin-releasing hormone agonist in gonadotropin deficiency. Fertil Steril. 2010;94(7):2697-2702.

Blumenfeld Z. Endocrine prevention of chemotherapy-induced ovarian failure. Future Oncol. 2016;12(14):1671-1674.

Blumenfeld Z, Evron A. Preserving fertility when choosing chemotherapy regimens - the role of gonadotropin-releasing hormone agonists. Expert Opin Pharmacother. 2015;16(7):1009-1020.

Engel JB, Schally AV. Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone. Nat Clin Pract Endocrinol Metab. 2007;3(2):157-167.

Limonta P, Montagnani Marelli M, Mai S, et al. GnRH receptors in cancer: from cell biology to novel targeted therapeutic strategies. Endocr Rev. 2012;33(5):784-811.

Tan O, Bukulmez O. Biochemistry, molecular biology and cell biology of gonadotropin-releasing hormone antagonists. Curr Opin Obstet Gynecol. 2011;23(4):238-244.

Jackson IM. Thyrotropin-releasing hormone. N Engl J Med. 1982;306(3):145-155.

Magner JA. Thyroid-stimulating hormone: biosynthesis, cell biology, and bioactivity. Endocr Rev. 1990;11(2):354-385.

Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol. 2004;44:525-557.

Black PH. Stress and the inflammatory response: a review of neurogenic inflammation. Brain Behav Immun. 2002;16(6):622-653.

Matsoukas MT, Spyroulias GA. Dynamic properties of the growth hormone releasing hormone receptor (GHRHR) and molecular determinants of GHRH binding. Mol Biosyst. 2017;13(7):1313-1322.

Freeman ME, Kanyicska B, Lerant A, et al. Prolactin: structure, function, and regulation of secretion. Physiol Rev. 2000;80(4):1523-1631.

Schultz W. Updating dopamine reward signals. Curr Opin Neurobiol. 2013;23(2):229-238.

Stueven AK, Kayser A, Wetz C, et al. Somatostatin Analogues in the Treatment of Neuroendocrine Tumors: Past, Present and Future. Int J Mol Sci. 2019;20(12).

Ampofo E, Nalbach L, Menger MD, et al. Regulatory Mechanisms of Somatostatin Expression. Int J Mol Sci. 2020;21(11).

Gomes-Porras M, Cárdenas-Salas J, Álvarez-Escolá C. Somatostatin Analogs in Clinical Practice: a Review. Int J Mol Sci. 2020;21(5).

Rogoza O, Megnis K, Kudrjavceva M, et al. Role of Somatostatin Signalling in Neuroendocrine Tumours. Int J Mol Sci. 2022;23(3).

Gábriel R. Neuropeptides and diabetic retinopathy. Br J Clin Pharmacol. 2013;75(5):1189-1201.

Perkinson MR, Kim JS, Iremonger KJ, et al. Visualising oxytocin neurone activity in vivo: The key to unlocking central regulation of parturition and lactation. J Neuroendocrinol. 2021;33(11):e13012.

Ellis JA, Brown CM, Barger B, et al. Influence of Maternal Obesity on Labor Induction: A Systematic Review and Meta-Analysis. J Midwifery Womens Health. 2019;64(1):55-67.

Birnbaumer M. Vasopressin receptors. Trends Endocrinol Metab. 2000;11(10):406-410.

Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. 2017;43(3):304-377.

Ceccatelli S, Eriksson M, Hökfelt T. Distribution and coexistence of corticotropin-releasing factor-, neurotensin-, enkephalin-, cholecystokinin-, galanin- and vasoactive intestinal polypeptide/peptide histidine isoleucine-like peptides in the parvocellular part of the paraventricular nucleus. Neuroendocrinology. 1989;49(3):309-323.

Rostène WH. Neurobiological and neuroendocrine functions of the vasoactive intestinal peptide (VIP). Prog Neurobiol. 1984;22(2):103-129.

Sarkar DK. Evidence for prolactin feedback actions on hypothalamic oxytocin, vasoactive intestinal peptide and dopamine secretion. Neuroendocrinology. 1989;49(5):520-524.

Lam KS, Srivastava G, Lechan RM, et al. Estrogen regulates the gene expression of vasoactive intestinal peptide in the anterior pituitary. Neuroendocrinology. 1990;52(5):417-421.

Bardrum B, Ottesen B, Fahrenkrug J, et al. Release of oxytocin and vasopressin by intracerebroventricular vasoactive intestinal polypeptide. Endocrinology. 1988;123(5):2249-2254.

West A, Vojta PJ, Welch DR, et al. Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1). Genomics. 1998;54(1):145-148.

Pinilla L, Aguilar E, Dieguez C, et al. Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiol Rev. 2012;92(3):1235-1316.

Jiang Y, Berk M, Singh LS, et al. KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metastasis. 2005;22(5):369-376.

Tomikawa J, Uenoyama Y, Ozawa M, et al. Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain. Proc Natl Acad Sci U S A. 2012;109(20):E1294-1301.

Watanabe Y, Uenoyama Y, Suzuki J, et al. Oestrogen-induced activation of preoptic kisspeptin neurones may be involved in the luteinising hormone surge in male and female Japanese monkeys. J Neuroendocrinol. 2014;26(12):909-917.

Rance NE. Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback. Peptides. 2009;30(1):111-122.

Abbara A, Eng PC, Phylactou M, et al. Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders. J Clin Invest. 2020;130(12):6739-6753.

Hoskova K, Kayton Bryant N, Chen ME, et al. Kisspeptin Overcomes GnRH Neuronal Suppression Secondary to Hyperprolactinemia in Humans. J Clin Endocrinol Metab. 2022;107(8):e3515-e3525.

Ishikawa K, Tanaka A, Kogame A, et al. Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model. Eur J Pharmacol. 2018;828:126-134.