Pilonidal Sinüs Hastalığı ve Tedavisinde Total Eksizyon-Primer Onarım ile İnsizyon-Küretaj Tekniklerinin Karşılaştırılması

Tam A, Steen CJ, Chua J,et al. Pilonidal sinus: an overview of historical and current management modalities. Updates Surg. 2024 Jun;76(3):803-810. doi: 10.1007/s13304-024-01799-2. Epub 2024 Mar 25. PMID: 38526695; PMCID: PMC11129967

Mahmood F, Hussain A, Akingboye A. Pilonidal sinus disease: Review of current practice and prospects for endoscopic treatment. Ann Med Surg (Lond). 2020 Aug 1;57:212-217. doi: 10.1016/j.amsu.2020.07.050. PMID: 32793341; PMCID: PMC7415633.

Hemmingsson O, Binnermark F, Odensten C, et al. Excision and suture in the midline versus Karydakis flap surgery for pilonidal sinus: randomized clinical trial, BJS Open, Volume 6, Issue 2, April 2022, zrac007, https://doi.org/10.1093/bjsopen/zrac007

Hodges R. , Pilonidal Sinus, Boston Med. Surg. J.,103 (1880) 485-48

Chinn B., Outpatient management of pilonidal disease, Semin. Colon Rectal Surg., 14 (4) (2003), pp. pp166-172

Buie L., Jeep disease, South. Med. J., 37 (1944), p. 103

Ballas K, Psarras K, Rafailidis S, et al.,Interdigital pilonidal sinus in a hairdresser. J Hand Surg Br. 2006 Jun;31(3):290-1. doi: 10.1016/j.jhsb.2005.12.002. Epub 2006 Jan 20. PMID: 16427726.

Gage M. Pilonidal sınus: an explanatıon of ıts embryologıc development. Arch Surg. 1935;31(2):175–189. doi:10.1001/archsurg.1935.01180140003001

Karydakis GE. Easy and successful treatment of pilonidal sinus after explanation of its causative process. Aust N Z J Surg. 1992 May;62(5):385-9. doi: 10.1111/j.1445-2197.1992.tb07208.x. PMID: 1575660.

Bascom J. Pilonidal disease: origin from follicles of hairs and results of follicle removal as treatment. Surgery. 1980 May;87(5):567-72. PMID: 7368107.

Søndenaa K, Pollard ML. Histology of chronic pilonidal sinus. APMIS. 1995 Apr;103(4):267-72. doi: 10.1111/j.1699-0463.1995.tb01105.x. PMID: 7542011.

Søndenaa K., Andersen E., Nesvik I.S.J, et al.,Patient characteristic and symptoms in chronic pilonidal sinus disease, Int. J. Colorectal Dis., 10 (1995), pp. 39-42

Ommer A., Iesalnieks I., The management of pilonidal sinus, Dtsch Arztebl Int, 116 (1–2) (2019 Jan 7), pp. 12-21

Notaro J.R. , Management of recurrent pilonidal disease, Semin. Colon Rectal Surg., 14 (4) (2003), pp. 173-185

Akinci O.F., Bozer M., Uzunkoy A., et al.,Incidence and aetiological factors in pilonidal sinus among Turkish soldiers, Eur. J. Surg., 165 (4) (1999), pp. 339-342

Burney R., Treatment of pilonidal disease by minimal surgical excision under local anesthesia with healing by secondary intention: results in over 500 patients, Surgery, 164 (6) (2018), pp. 1217-1222

Harries R., Al-Qallaf A., J. Torkington, et al.,Management of sacrococcygeal pilonidal sinus disease, Int. Wound J., 16 (2) (2018), p. 370

Beal E., Hind M.,Bradburn E., et al.,Design and rationale of the Pilonidal sinus Treatment-STudying the OPtions (PITSTOP) study: a multicentre cohort, nested mixed-methods case study and discrete choice experiment, Int. J. Surg., 59 (2018) (2018)

Khodakaram K., Stark J., Höglund I., et al.,Minimal excision and primary suture is a cost-efficient definitive treatment for pilonidal disease with low morbidity: a population-based interventional and a cross-sectional cohort study World journal of surgery, World J. Surg., 41 (5) (2017), p. 129

Iesalnieks I, Ommer A. The Management of Pilonidal Sinus. Dtsch Arztebl Int. 2019 Jan 7;116(1-2):12-21. doi: 10.3238/arztebl.2019.0012. PMID: 30782310; PMCID: PMC6384517.

da Silva JH. Pilonidal cyst: cause and treatment. Dis Colon Rectum. 2000 Aug;43(8):1146-56. doi: 10.1007/BF02236564. PMID: 10950015.

Hull TL, Wu J. Pilonidal disease. Surg Clin North Am. 2002 Dec;82(6):1169-85. doi: 10.1016/s0039-6109(02)00062-2. PMID: 12516846.

Mohanna PN, Al-Sam SZ, Flemming AF. Subungual pilonidal sinus of the hand in a dog groomer. Br J Plast Surg. 2001 Mar;54(2):176-8. doi: 10.1054/bjps.2000.3457. PMID: 11207136.

Moyer DG. Pilonidal cyst of the scalp. Arch Dermatol. 1972 Apr;105(4):578-9. PMID: 5017269.

Chintapatla, S., Safarani, N., Kumar, S. et al. Sacrococcygeal pilonidal sinus: historical review, pathological insight and surgical options. Tech Coloproctol 7, 3–8 (2003). https://doi.org/10.1007/s101510300001

Patey DH., Scarff RW., Pathology of postanal pilonidal sinus; its bearing on treatment. Lancet. 1946 Oct 5;2(6423):484-6. doi: 10.1016/s0140-6736(46)91756-4. PMID: 20998923.

Patey D. Pilonidal sinus: a postscript. Lancet. 1971 Jan 30;1(7692):245. doi: 10.1016/s0140-6736(71)90991-3. PMID: 4099911.

Jensen S., Harling H., Prognosis after simple incision and drainage of the first initial acute pilonidal abscess, Br. J. Surg., 75 (1988), pp. 60-61

Iesalnieks I., Ommer A., Petersen S., et al. German national guideline on the management of pilonidal disease. Langenbecks Arch Surg. 2016 Aug;401(5):599-609. doi: 10.1007/s00423-016-1463-7. Epub 2016 Jun 16. PMID: 27311698.

Garg P., Menon GR., Gupta V.. Laying open (deroofing) and curettage of sinus as treatment of pilonidal disease: a systematic review and meta-analysis. ANZ J Surg. 2016 Jan-Feb;86(1-2):27-33. doi: 10.1111/ans.13377. Epub 2015 Nov 27. PMID: 26612320.

Enriquez-Navascues JM., Emparanza JI., Alkorta M.et al.,Meta-analysis of randomized controlled trials comparing different techniques with primary closure for chronic pilonidal sinus. Tech Coloproctol. 2014 Oct;18(10):863-72. doi: 10.1007/s10151-014-1149-5. Epub 2014 Apr 30. PMID: 24845110.

Marks J., Harding K., Hughes L., et al.,Pilonidal sinus excision: healing by open granulation, Br. J. Surg., 72 (8) (1985), pp. 637-640

Mohamed H.A., Kadry I., Adly S., Comparison between three therapeutic modalities for non-complicated pilonidal sinus disease, Surgeon, 3 (2) (2005), pp. 73-77

Nelson J., Billingham R., Pilonidal disease and hidradenitis suppurativa, The ASCRS Textbook of Colon and Rectal Surgery, Springer, New York, NY (2007), pp. 228-239

Solla JA., Rothenberger DA., Chronic pilonidal disease. An assessment of 150 cases. Dis Colon Rectum. 1990 Sep;33(9):758-61. doi: 10.1007/BF02052321. PMID: 2390911.

Karakayali F., Karagulle E., Karabulut Z., et al. Unroofing and marsupialization vs. rhomboid excision and Limberg flap in pilonidal disease: a prospective, randomized, clinical trial. Dis Colon Rectum. 2009 Mar;52(3):496-502. doi: 10.1007/DCR.0b013e31819a3ec0. PMID: 19333052.

Al-Khamis A., McCallum I., King PM., et al. Healing by primary versus secondary intention after surgical treatment for pilonidal sinus. Cochrane Database Syst Rev. 2010 Jan 20;2010(1):CD006213. doi: 10.1002/14651858.CD006213.pub3. PMID: 20091589; PMCID: PMC7055199.

Hameed K., Outcome of Surgery for Chronic Natal Cleft Pilonidal Sinus: A Randomized Trial of Open Compared with Closed Technique, Medical Forums, Vol. 12, 2001, pp. 20-23.

Khawaja HT., Bryan S., Weaver PC., Treatment of natal cleft sinus: a prospective clinical and economic evaluation. BMJ. 1992 May 16;304(6837):1282-3. doi: 10.1136/bmj.304.6837.1282. PMID: 1606429; PMCID: PMC1881859.

Milone M., Velotti N., Manigrasso M., et al., Long-term follow-up for pilonidal sinus surgery: A review of literature with metanalysis. Surgeon. 2018 Oct;16(5):315-320. doi: 10.1016/j.surge.2018.03.009. Epub 2018 Apr 24. PMID: 29699781.

Humphries AE., Duncan JE., Evaluation and management of pilonidal disease. Surg Clin North Am., 2010 Feb;90(1):113-24, Table of Contents. doi: 10.1016/j.suc.2009.09.006. PMID: 20109636.

Bascom J., Pilonidal disease: origin from follicles of hairs and results of follicle removal as treatment. Surgery. 1980 May;87(5):567-72. PMID: 7368107.

Senapati A., Cripps NP., Thompson MR., Bascom's operation in the day-surgical management of symptomatic pilonidal sinus. Br J Surg. 2000 Aug;87(8):1067-70. doi: 10.1046/j.1365-2168.2000.01472.x. PMID: 10931052.

Abdelrazeq AS., Rahman M., Botterill ID., et al. Short-term and long-term outcomes of the cleft lift procedure in the management of nonacute pilonidal disorders. Dis Colon Rectum. 2008 Jul;51(7):1100-6. doi: 10.1007/s10350-008-9262-z. Epub 2008 May 10. PMID: 18470564.

Bascom J., Bascom T.,Utility of the cleft lift procedure in refractory pilonidal disease. Am J Surg. 2007 May;193(5):606-9; discussion 609. doi: 10.1016/j.amjsurg.2007.01.008. PMID: 17434365.

Karydakis GE., New approach to the problem of pilonidal sinus. Lancet. 1973 Dec 22;2(7843):1414-5. doi: 10.1016/s0140-6736(73)92803-1. PMID: 4128725.

Karydakis GE., Easy and successful treatment of pilonidal sinus after explanation of its causative process. Aust N Z J Surg. 1992 May;62(5):385-9. doi: 10.1111/j.1445-2197.1992.tb07208.x. PMID: 1575660.

Ozgültekin R., Ersan Y., Ozcan M., et al.,Die Therapie des Sinus pilonidalis mit dem Transpositionslappen nach Limberg [Therapy of pilonidal sinus with the Limberg transposition flap]. Chirurg. 1995 Mar;66(3):192-5. German. PMID: 7750389.

Akca T., Colak T., Ustunsoy B., et al., Randomized clinical trial comparing primary closure with the Limberg flap in the treatment of primary sacrococcygeal pilonidal disease. Br J Surg. 2005 Sep;92(9):1081-4. doi: 10.1002/bjs.5074. PMID: 16078300.

Hodgson WJ., Greenstein RJ.,A comparative study between Z-plasty and incision and drainage or excision with marsupialization for pilonidal sinuses. Surg Gynecol Obstet. 1981 Dec;153(6):842-4. PMID: 7029758.

Fazeli MS., Adel MG., Lebaschi AH., Comparison of outcomes in Z-plasty and delayed healing by secondary intention of the wound after excision of the sacral pilonidal sinus: results of a randomized, clinical trial. Dis Colon Rectum. 2006 Dec;49(12):1831-6. doi: 10.1007/s10350-006-0726-8. PMID: 17080281.

Demiryilmaz I., Yilmaz I., Peker K.,et al. Application of fasciocutaneous V-Y advancement flap in primary and recurrent sacrococcygeal pilonidal sinus disease. Med Sci Monit. 2014 Jul 21;20:1263-6. doi: 10.12659/MSM.890752. PMID: 25042095; PMCID: PMC4114698.

Koca YS., Yıldız I., Ugur M., et al., The V-Y flap technique in complicated and recurrent pilonidal sinus disease. Ann Ital Chir. 2018;89:66-69. PMID: 29629896.

McCallum I., King PM., Bruce J., Healing by primary versus secondary intention after surgical treatment for pilonidal sinus. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD006213. doi: 10.1002/14651858.CD006213.pub2. Update in: Cochrane Database Syst Rev. 2010 Jan 20;(1):CD006213. doi: 10.1002/14651858.CD006213.pub3. PMID: 17943897.

Meinero P., Mori L., Gasloli G., Endoscopic pilonidal sinus treatment (E.P.Si.T.). Tech Coloproctol. 2014 Apr;18(4):389-92. doi: 10.1007/s10151-013-1016-9. Epub 2013 May 17. PMID: 23681300.

Milone M., Musella M., Di Spiezio Sardo A., et al. Video-assisted ablation of pilonidal sinus: a new minimally invasive treatment--a pilot study. Surgery. 2014 Mar;155(3):562-6. doi: 10.1016/j.surg.2013.08.021. Epub 2013 Oct 25. PMID: 24300343.

Milone M., Fernandez LM., Musella M., et al., Safety and Efficacy of Minimally Invasive Video-Assisted Ablation of Pilonidal Sinus: A Randomized Clinical Trial. JAMA Surg. 2016 Jun 1;151(6):547-53. doi: 10.1001/jamasurg.2015.5233. PMID: 26819186.

Milone M., Velotti N., Manigrasso M., et al., Long-term results of a randomized clinical trial comparing endoscopic versus conventional treatment of pilonidal sinus. Int J Surg. 2020 Feb;74:81-85. doi: 10.1016/j.ijsu.2019.12.033. Epub 2020 Jan 9. PMID: 31926328.

Gecim IE., Goktug UU., Celasin H., Endoscopic Pilonidal Sinus Treatment Combined With Crystalized Phenol Application May Prevent Recurrence. Dis Colon Rectum. 2017 Apr;60(4):405-407. doi: 10.1097/DCR.0000000000000778. PMID: 28267008.

Milone M., Velotti N., Manigrasso M., et al., Video-assisted ablation of pilonidal sinus (VAAPS) versus sinusectomy for treatment of chronic pilonidal sinus disease: a comparative study. Updates Surg. 2019 Mar;71(1):179-183. doi: 10.1007/s13304-018-00611-2. Epub 2018 Dec 12. PMID: 30542957.

Kalaiselvan R., Bathla S., Allen W., et al., Minimally invasive techniques in the management of pilonidal disease. Int J Colorectal Dis. 2019 Apr;34(4):561-568. doi: 10.1007/s00384-019-03260-y. Epub 2019 Feb 27. PMID: 30810799.

Tien T., Athem R., Arulampalam T., Outcomes of endoscopic pilonidal sinus treatment (EPSiT): a systematic review. Tech Coloproctol. 2018 May;22(5):325-331. doi: 10.1007/s10151-018-1803-4. Epub 2018 May 31. PMID: 29850944.

Emile SH., Elfeki H., Shalaby M., et al., Endoscopic pilonidal sinus treatment: a systematic review and meta-analysis. Surg Endosc. 2018 Sep;32(9):3754-3762. doi: 10.1007/s00464-018-6157-5. Epub 2018 Mar 30. PMID: 29603009.

Chia CL., Tay VW., Mantoo SK., Endoscopic pilonidal sinus treatment in the Asian population. Surg Laparosc Endosc Percutan Tech. 2015 Jun;25(3):e95-7. doi: 10.1097/SLE.0000000000000131. PMID: 26018049.

Stauffer VK., Luedi MM., Kauf P., et al., Common surgical procedures in pilonidal sinus disease: A meta-analysis, merged data analysis, and comprehensive study on recurrence. Sci Rep. 2018 Feb 15;8(1):3058. doi: 10.1038/s41598-018-20143-4. PMID: 29449548; PMCID: PMC5814421.

Pappas AF., Christodoulou DK., A new minimally invasive treatment of pilonidal sinus disease with the use of a diode laser: a prospective large series of patients. Colorectal Dis. 2018 Aug;20(8):O207-O214. doi: 10.1111/codi.14285. Epub 2018 Jun 27. PMID: 29878584.

Kaymakcioglu N., Yagci G., Simsek A., et al., Treatment of pilonidal sinus by phenol application and factors affecting the recurrence. Tech Coloproctol. 2005 Apr;9(1):21-4. doi: 10.1007/s10151-005-0187-4. PMID: 15868494.

Maurıce BA., Greenwood RK., A Conservatıve Treatment Of Pılonıdal Sınus. Br J Surg. 1964 Jul;51:510-2. doi: 10.1002/bjs.1800510711. PMID: 14199061.

Dogru O., Camci C., Aygen E., et al., Pilonidal sinus treated with crystallized phenol: an eight-year experience. Dis Colon Rectum. 2004 Nov;47(11):1934-8. doi: 10.1007/s10350-004-0720-y. PMID: 15622588.

Calikoglu I., Gulpinar K., Oztuna D., et al., Phenol Injection Versus Excision With Open Healing in Pilonidal Disease: A Prospective Randomized Trial. Dis Colon Rectum. 2017 Feb;60(2):161-169. doi: 10.1097/DCR.0000000000000717. PMID: 28059912.

Kayaalp C., Aydin C., Review of phenol treatment in sacrococcygeal pilonidal disease. Tech Coloproctol. 2009 Sep;13(3):189-93. doi: 10.1007/s10151-009-0519-x. Epub 2009 Aug 5. PMID: 19655223.

Lund J., Tou S., Doleman B., et al., Fibrin glue for pilonidal sinus disease. Cochrane Database Syst Rev. 2017 Jan 13;1(1):CD011923. doi: 10.1002/14651858.CD011923.pub2. PMID: 28085995; PMCID: PMC6464784.

al-Hassan HK., Francis IM., Neglén P., Primary closure or secondary granulation after excision of pilonidal sinus? Acta Chir Scand. 1990 Oct;156(10):695-9. PMID: 2264427.

Dalenback I., Magnusson D., Wedel N., et al., Prospective follow up after ambulatory plain midline excision of Pilonidal sinus and primary suture UIlder local anaesthesia - efficent, sifficient and persistent Color ectal Dis 2004; 6: 488-93

Akinci OF., Coskun A., Uzunköy A., Simple and effective surgical treatment of pilonidal sinus: asymmetric excision and primary closure using suction drain and subcuticular skin closure. Dis Colon Rectum. 2000 May;43(5):701-6; discussion 706-7. doi: 10.1007/BF02235591. PMID: 10826434.

Gupta PJ., A randomized study between excision and marsupialization and radiofrequency sinus excision in sacro-coccygeal pilonidal disease. Curr Surg. 2004 May-Jun;61(3):307-12. doi: 10.1016/j.cursur.2003.11.015. PMID: 15165772.

Kronborg O., Christensen K., Zimmermann-Nielsen C., Chronic pilonidal disease: a randomized trial with a complete 3-year follow-up. Br J Surg. 1985 Apr;72(4):303-4. doi: 10.1002/bjs.1800720418. PMID: 3886069.

Gencosmanoglu R., Inceoglu R., Modified lay-open (incision, curettage, partial lateral wall excision and marsupialization) versus total excision with primary closure in the treatment of chronic sacrococcygeal pilonidal sinus: a prospective, randomized clinical trial with a complete two-year follow-up. Int J Colorectal Dis. 2005 Sep;20(5):415-22. doi: 10.1007/s00384-004-0710-5. Epub 2005 Feb 16. PMID: 15714292.

Allen-Mersh TG., Pilonidal sinus: finding the right track for treatment. Br J Surg. 1990 Feb;77(2):123-32. doi: 10.1002/bjs.1800770203. PMID: 2180534.

Al-Jaberi TM., Excision and simple primary closure of chronic pilonidal sinus. Eur J Surg. 2001 Feb;167(2):133-5. doi: 10.1080/110241501750070600. PMID: 11266254.

Søndenaa K., Andersen E., Søreide JA., Morbidity and short term results in a randomised trial of open compared with closed treatment of chronic pilonidal sinus. Eur J Surg. 1992 Jun-Jul;158(6-7):351-5. PMID: 1356467.

Füzün M., Bakir H., Soylu M., et al, Which technique for treatment of pilonidal sinus--open or closed? Dis Colon Rectum. 1994 Nov;37(11):1148-50. doi: 10.1007/BF02049819. PMID: 7956585.

Søndenaa K., Nesvik I., Andersen E., et al., Recurrent pilonidal sinus after excision with closed or open treatment: final result of a randomised trial. Eur J Surg. 1996 Mar;162(3):237-40. PMID: 8695740.

Tezel E., A new classification according to naviculararea concept for sacrococcygeal pilonidal disease.Colorectal Dis 2007;9:575-576.

Beal EM., Lee MJ., Hind D., et al., A systematic review of classification systems for pilonidal sinus. Tech Coloproctol. 2019 May;23(5):435-443. doi: 10.1007/s10151-019-01988-x. Epub 2019 May 16. PMID: 31098861; PMCID: PMC6620258.

Yavuz, Y., Yıldırım M. A., Cakır M., et al., (2020). Classification of Pilonidal Sinus Disease According toPhysical Examination, Ultrasonography and MagneticResonance Imaging Findings. Türk Kolon ve Rektum Hastalıkları Dergisi , 30(4), 261 - 267. doi.org/10.4274/tjcd.galenos.2020.2020-3-9

Güzel G., Pilonidal sinus hastalığı ve tedavisinde total eksizyon-primer onarım ile insizyon-küretaj tekniklerinin karşılaştırılması, Emek K. (danışman), 2005, Akdeniz Üniversitesi Tıp Fakültesi Genel Cerrahi Anabilimdalı Uzmanlık Tezi, Ulusal Tez Merkezi (tez no: 378038) [online] (https://tez.yok.gov.tr/UlusalTezMerkezi/tezDetay.jsp?id=hlChUNtRcYDlcHauWSAwbg&no=f2SLkBMHoMtHBK9EiExq0w [ Accessed: 22th September 2025]