Acil Hemodiyaliz ve Hemoperfüzyon

Özet

Hemodiyaliz(HD), sıvı dengesini normale getiren, anormal elektrolit ve çözünen maddeleri düzeltebilen, renal replasman tedavi (RRT) yöntemidir. Üremik toksinler ve aşırı doz ilaç alımları dolaşımdan temizlenerek üremik belirtileri daha düşük seviyeye çekilebilmektedir. Hemoperfüzyon, endojen ve ekzojen toksinlerin ve zararlı aracıların, adsorpsiyon yolu ile vücut dışı eliminasyonunun yapıldığı bir tekniktir. Tek başına bir cihaz veya ekstrakorporeal membran oksijenasyonunun (Extra Corporeal Membrane Oxygenation, ECMO) bir parçası olarak veya renal replasman prosedürüne entegre olarak uygulanmaktadır. HD, akut böbrek hasarı (ABH) hastalarının yaşam sürelerini uzatmayı amaçlayan yaygın olarak kullanılan bir tedavi yöntemi olarak bilinmekle birlikte aynı klinik durumda hemoperfüzyon adsorbanları hedef patojenik faktörleri spesifik olarak bağlayıp uzaklaştırma görevine sahiptir. Sonuç olarak hem hemodiyaliz hem hemoperfüzyon klinik belirtiler veya organ yetmezliğine neden olmadan önce hayat kurtarıcı bir rol oynamaktadır

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