Multiloküler Kistik ve Düşük Malignite Potansiyelli Böbrek Neoplazisi

Yazarlar

Berrak Gümüşkaya

Özet

Düşük nükleer dereceli berrak hücrelerle döşeli multiloküler kistik tümör. Düşük malignite potansiyeli mevcuttur. Berrak hücreli RCC ile benzer genetik özellikler izlenebilir.

Referanslar

Paner GP, Cimadamore A, Darrell CM, Tretiakova MS, Montironi R. Surgical pathology of cystic renal cell carcinomas: is there an overestimation of malignancy? Diagn Histopathol. 2020;26(7):320-329. doi:10.1016/J.MPDHP.2020.04.003/ASSET/5321214F-9ED2-4C41-8D0C-E35A540CD5C4/MAIN.ASSETS/GR6.SML

Tretiakova M, Mehta V, Kocherginsky M, et al. Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum. Virchows Arch. 2018;473(1):85-93. doi:10.1007/S00428-018-2371-8

Frew IJ, Moch H. A clearer view of the molecular complexity of clear cell renal cell carcinoma. Annu Rev Pathol. 2015;10:263-289. doi:10.1146/ANNUREV-PATHOL-012414-040306

Kim SH, Park WS, Chung J. SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from clear cell renal cell carcinoma with cystic change. Investig Clin Urol. 2019;60(3):148-155. doi:10.4111/ICU.2019.60.3.148

Kuroda N, Ohe C, Mikami S, et al. Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. Histol Histopathol. 2012;27(8):969-974. doi:10.14670/HH-27.969

Gong K, Zhang N, He Z, Zhou L, Lin G, Na Y. Multilocular cystic renal cell carcinoma: an experience of clinical management for 31 cases. J Cancer Res Clin Oncol. 2008;134(4):433-437. doi:10.1007/S00432-007-0302-1

Srigley JR, Delahunt B, Eble JN, et al. The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. Am J Surg Pathol. 2013;37(10):1469-1489. doi:10.1097/PAS.0B013E318299F2D1

Chen S, Jin B, Xu L, et al. Cystic renal cell carcinoma: a report of 67 cases including 4 cases with concurrent renal cell carcinoma. BMC Urol. 2014;14(1). doi:10.1186/1471-2490-14-87

Li T, Chen J, Jiang Y, et al. Multilocular Cystic Renal Cell Neoplasm of Low Malignant Potential: A Series of 76 Cases. Clin Genitourin Cancer. 2016;14(6):e553-e557. doi:10.1016/J.CLGC.2016.03.017

Westerman ME, Cheville JC, Lohse CM, et al. Long-Term Outcomes of Patients With Low Grade Cystic Renal Epithelial Neoplasms. Urology. 2019;133:145-150. doi:10.1016/J.UROLOGY.2019.07.017

Bhatt JR, Jewett MAS, Richard PO, et al. Multilocular Cystic Renal Cell Carcinoma: Pathological T Staging Makes No Difference to Favorable Outcomes and Should be Reclassified. J Urol. 2016;196(5):1350-1355. doi:10.1016/J.JURO.2016.05.118

Suzigan S, López-Beltrán A, Montironi R, et al. Multilocular cystic renal cell carcinoma : a report of 45 cases of a kidney tumor of low malignant potential. Am J Clin Pathol. 2006;125(2):217-222. doi:10.1309/AH6F-C77P-YR2V-6YAY

Schoots IG, Zaccai K, Hunink MG, Verhagen PCMS. Bosniak Classification for Complex Renal Cysts Reevaluated: A Systematic Review. J Urol. 2017;198(1):12-21. doi:10.1016/J.JURO.2016.09.160

Pitra T, Pivovarcikova K, Alaghehbandan R, et al. A Comprehensive Commentary on the Multilocular Cystic Renal Neoplasm of Low Malignant Potential: A Urologist’s Perspective. Cancers (Basel). 2022;14(3). doi:10.3390/CANCERS14030831

Kim SH, Park B, Joo J, et al. Retrospective analysis of 25 immunohistochemical tissue markers for differentiating multilocular cystic renal neoplasm of low malignant potential and multicystic renal cell carcinoma. Histol Histopathol. 2018;33(6):589-596. doi:10.14670/HH-11-958

Williamson SR, Halat S, Eble JN, et al. Multilocular cystic renal cell carcinoma: similarities and differences in immunoprofile compared with clear cell renal cell carcinoma. Am J Surg Pathol. 2012;36(10):1425-1433. doi:10.1097/PAS.0B013E31825B37F0

Von Teichman A, Compérat E, Behnke S, Storz M, Moch H, Schraml P. VHL mutations and dysregulation of pVHL- and PTEN-controlled pathways in multilocular cystic renal cell carcinoma. Mod Pathol. 2011;24(4):571-578. doi:10.1038/MODPATHOL.2010.222

Halat S, Eble JN, Grignon DJ, et al. Multilocular cystic renal cell carcinoma is a subtype of clear cell renal cell carcinoma. Mod Pathol. 2010;23(7):931-936. doi:10.1038/MODPATHOL.2010.78

Perrino CM, Orien JA, Tretter JG, Zhao W, Zynger DL. Clinical Utility of Fluorescence In Situ Hybridization (FISH) for Deletion of Chromosome 3p in the Work-up of Renal Masses. Appl Immunohistochem Mol Morphol. 2019;27(7):549-557. doi:10.1097/PAI.0000000000000676

Mantilla JG, Antic T, Tretiakova M. GATA3 as a valuable marker to distinguish clear cell papillary renal cell carcinomas from morphologic mimics. Hum Pathol. 2017;66:152-158. doi:10.1016/J.HUMPATH.2017.06.016

Sun BL, Abern M, Garzon S, Setty S. Cystic nephroma/mixed epithelial stromal tumor: a benign neoplasm with potential for recurrence. Int J Surg Pathol. 2015;23(3):238-242. doi:10.1177/1066896914563391

Tretiakova MS. Chameleon TFE3-translocation RCC and How Gene Partners Can Change Morphology: Accurate Diagnosis Using Contemporary Modalities. Adv Anat Pathol. 2022;29(3):131-140. doi:10.1097/PAP.0000000000000332

İndir

Yayınlanan

25 Kasım 2025

Lisans

Lisans