Uzun Yaşam Diyeti

S., Kumar, S., Chand, A., & Adiga, M. (2017). A REVIEW ON ADAPTOGENIC ACTIVITY OF ASHWAGANDHA (WITHANIA SOMNIFERA): AN AYURVEDIC APPRAISAL. Journal of Pharmaceutical and Scientific Innovation, 6, 94-98. https://doi.org/10.7897/2277-4572.06561.

8 Tips to Add Mindfulness to Your Mealtime (healthline.com)

A. Shekhidem, H., Sharvit, L., Leman, E., Manov, I., Roichman, A., Holtze, S., ... & Atzmon, G. (2019). Telomeres and longevity: a cause or an effect?. International Journal of Molecular Sciences, 20(13), 3233.

Adamovich, Y., Rousso-Noori, L., Zwighaft, Z., Neufeld-Cohen, A., Golik, M., Kraut-Cohen, J., Wang, M., Han, X., & Asher, G. (2014). Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. Cell metabolism, 19(2), 319–330. https://doi.org/10.1016/j.cmet.2013.12.016

Afanas’ev, I. (2010). Signaling and damaging functions of free radicals in aging—free radical theory, hormesis, and TOR. Aging and disease, 1(2), 75.

Afzal, M.; Safer, A.M.; Menon, M. Green Tea Polyphenols and Their Potential Role in Health and Disease. Inflammopharmacology 2015, 23, 151–161.

Agarwal, B., Campen, M., Channell, M., Wherry, S., Varamini, B., Davis, J., Baur, J., & Smoliga, J. (2013). Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium.. International journal of cardiology, 166 1, 246-8 . https://doi.org/10.1016/j.ijcard.2012.09.027.

Airhart, S. E., Shireman, L. M., Risler, L. J., Anderson, G. D., Nagana Gowda, G. A., Raftery, D., ... & O’Brien, K. D. (2017). An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. PloS one, 12(12), e0186459.

Akhgarjand, C., Asoudeh, F., Bagheri, A., Kalantar, Z., Vahabi, Z., Shab-Bidar, S., Rezvani, H., & Djafarian, K. (2022). Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta‐analysis of randomized controlled trials. Phytotherapy Research, 36, 4115 - 4124. https://doi.org/10.1002/ptr.7598.

Alharbi, K. S., Afzal, O., Altamimi, A. S. A., Almalki, W. H., Kazmi, I., Al‐Abbasi, F. A., ... & Albratty, M. (2022). A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age‐related and kidney diseases. Journal of Food Biochemistry, 46(12), e14471.

Anand, R., Song, Y., Garg, S., Girotra, M., Sinha, A., Sivaraman, A., ... & Dutta, S. K. (2017). Effect of aging on the composition of fecal microbiota in donors for FMT and its impact on clinical outcomes. Digestive diseases and sciences, 62, 1002-1008.

Andres, S., Pevny, S., Ziegenhagen, R., Bakhiya, N., Schäfer, B., Hirsch‐Ernst, K. I., & Lampen, A. (2018). Safety aspects of the use of quercetin as a dietary supplement. Molecular nutrition & food research, 62(1), 1700447.

Anisimov, V., Popovich, I., Zabezhinski, M., Anisimov, S., Vesnushkin, G., & Vinogradova, I. (2006). Melatonin as antioxidant, geroprotector and anticarcinogen.. Biochimica et biophysica acta, 1757 5-6, 573-89 . https://doi.org/10.1016/J.BBABIO.2006.03.012.

Antonelou, M. H., Kriebardis, A. G., & Papassideri, I. S. (2010). Aging and death signalling in mature red cells: from basic science to transfusion practice. Blood Transfusion, 8(Suppl 3), s3

Astrup, A., Bertram, H. C., Bonjour, J. P., de Groot, L. C. P. G. M., Feeney, E. L., Garg, M. L., … & Soedamah-Muthu, S. S. (2019). WHO draft guidelines on dietary saturated and trans fatty acids: Time for a new approach? BMJ, 366, l4137.

Attia, P. (2023). Outlive: The science and art of longevity. Harmony.

BaHammam, A. S., & Pirzada, A. (2023). Timing Matters: The Interplay between Early Mealtime, Circadian Rhythms, Gene Expression, Circadian Hormones, and Metabolism-A Narrative Review. Clocks & sleep, 5(3), 507–535. https://doi.org/10.3390/clockssleep5030034

Balestrino, M., & Adriano, E. (2019). Beyond sports: Efficacy and safety of creatine supplementation in pathological or paraphysiological conditions of brain and muscle. Medicinal Research Reviews, 39, 2427 - 2459. https://doi.org/10.1002/med.21590.

Bana, B., & Cabreiro, F. (2019). The microbiome and aging. Annual review of genetics, 53(1), 239-261.

Baylis, D., Bartlett, D. B., Patel, H. P., & Roberts, H. C. (2013). Understanding how we age: insights into inflammaging. Longevity & healthspan, 2, 1-8.

Bechthold, A., Boeing, H., Tetens, I., Schwingshackl, L., & Nöthlings, U. (2018). Perspective: food-based dietary guidelines in Europe—scientific concepts, current status, and perspectives. Advances in nutrition, 9(5), 544-560.

Biagi, E., Rampelli, S., Turroni, S., Quercia, S., Candela, M., & Brigidi, P. (2017). The gut microbiota of centenarians: signatures of longevity in the gut microbiota profile. Mechanisms of ageing and development, 165, 180-184.

Bielak-Zmijewska, A.; Grabowska, W.; Ciolko, A.; Bojko, A.; Mosieniak, G.; Bijoch, Ł.; Sikora, E. The Role of Curcumin in the Modulation of Ageing. Int. J. Mol. Sci. 2019, 20, 1239.

Bogg, T., & Roberts, B. W. (2013). The case for conscientiousness: Evidence and implications for a personality trait marker of health and longevity. Annals of Behavioral Medicine, 45(3), 278-288.

Bourque, C. (2008). Central mechanisms of osmosensation and systemic osmoregulation. Nature Reviews Neuroscience, 9, 519-531. https://doi.org/10.1038/nrn2400.

Bozovic, D., Racic, M., & Ivkovic, N. (2013). Salivary cortisol levels as a biological marker of stress reaction. Med Arch, 67(5), 374-377.

Brown, R. P., & Gerbarg, P. L. (2009). Yoga breathing, meditation, and longevity. Annals of the New York Academy of Sciences, 1172(1), 54-62.

Brown, R. P., & Gerbarg, P. L. (2009). Yoga breathing, meditation, and longevity. Annals of the New York Academy of Sciences, 1172(1), 54-62.

Buboltz JB, Hendriksen S, Cooper JS. Hyperbaric Soft Tissue Radionecrosis. [Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482261/.

Buijze GA, Sierevelt IN, van der Heijden BC, Dijkgraaf MG, Frings-Dresen MH. The Effect of Cold Showering on Health and Work: A Randomized Controlled Trial. PLoS One. 2016 Sep 15;11(9):e0161749. doi: 10.1371/journal.pone.0161749. Erratum in: PLoS One.

By Corrie Pelc on February 23, 2024 — Fact checked by Jill Seladi-Schulman, Ph.D. / https://www.medicalnewstoday.c15om/articles/red-light-therapy-improves-blood-sugar-levels

Calder, P., & Yaqoob, P. (2009). Understanding Omega-3 Polyunsaturated Fatty Acids. Postgraduate Medicine, 121, 148 - 157. https://doi.org/10.3810/pgm.2009.11.2083.

Chai, B., Voort, J., Grofelnik, K., Eliasdottir, H., Klöss, I., & Perez-Cueto, F. (2019). Which Diet Has the Least Environmental Impact on Our Planet? A Systematic Review of Vegan, Vegetarian and Omnivorous Diets. Sustainability.

Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. Indian Journal of Psychological Medicine, 34, 255 - 262. https://doi.org/10.4103/0253-7176.106022.

Chang, J., Wang, Y., Shao, L., Laberge, R. M., Demaria, M., Campisi, J., … & Zhou, D. (2016). Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Nature Medicine, 22(1), 78–83. https://doi.org/10.1038/nm.4010

Chiavaroli, L., Nishi, S. K., Khan, T. A., Braunstein, C. R., Glenn, A. J., Mejia, S. B., … & Sievenpiper, J. L. (2018). Portfolio dietary pattern and cardiovascular disease: A systematic review and meta-analysis of controlled trials. Progress in Cardiovascular Diseases, 61(1), 43–53. https://doi.org/10.1016/j.pcad.2018.05.004

Circus, V. E., & Robison, R. (2019). Exploring perceptions of sustainable proteins and meat attachment. British Food Journal, 121(2), 533-545.

Clark, M. A., Springmann, M., Hill, J., & Tilman, D. (2019). Multiple health and environmental impacts of foods. Proceedings of the National Academy of Sciences, 116(46), 23357-23362.

Coimbra, B., Carvalho, C., Moretti, P., Mello, M., & Belangero, S. (2017). Stress-related telomere length in children: A systematic review.. Journal of psychiatric research, 92, 47-54 .

Coman, V., & Vodnar, D. C. (2020). Gut microbiota and old age: Modulating factors and interventions for healthy longevity. Experimental gerontology, 141, 111095.

Comfort, A. (1964). Ageing. The biology of senescence.

Coolbaugh, C.L., Damon, B.M., Bush, E.C. et al. Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content. Sci Rep 9, 13600 (2019). https://doi.org/10.1038/s41598-019-49936-x.

Corley, J. (2020). Adherence to the MIND diet is associated with 12-year all-cause mortality in older adults. Public Health Nutrition, 25, 358 - 367. https://doi.org/10.1017/S1368980020002979.

Craig, S. (2004). Betaine in human nutrition.. The American journal of clinical nutrition, 80 3, 539-49 . https://doi.org/10.1093/AJCN/80.3.539.

D’Amico, D., Andreux, P., Valdés, P., Singh, A., Rinsch, C., & Auwerx, J. (2021). Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.. Trends in molecular medicine. https://doi.org/10.1016/j.molmed.2021.04.009.

Daniels, A. A., Ge, X., Sunshine, M. J., Dreifke, D., Leonard, M., Kasu, Y., ... & Signer, R. A. (2024). 3055–ENHANCING TRANSLATION FIDELITY EXTENDS HEMATOPOIETIC STEM CELL LONGEVITY. Experimental Hematology, 137, 104377.

Dasanayaka, N., Sirisena, N., & Samaranayake, N. (2020). The effects of meditation on length of telomeres in healthy individuals: a systematic review. Systematic Reviews, 10. https://doi.org/10.1186/s13643-021-01699-1.

De Bandt, J. P., Coumoul, X., & Barouki, R. (2022). Branched-chain amino acids and insulin resistance, from protein supply to diet-induced obesity. Nutrients, 15(1), 68.

Deepika, & Maurya, P. K. (2022). Health benefits of quercetin in age-related diseases. Molecules, 27(8), 2498.

Deledda, Andrea et al. “Mitochondrial Aging and Senolytic Natural Products with Protective Potential.” International journal of molecular sciences vol. 23,24 16219. 19 Dec. 2022, doi:10.3390/ijms232416219

Derbyshire, E. (2017). Flexitarian Diets and Health: A Review of the Evidence-Based Literature. Frontiers in Nutrition, 3.

Dhana, K., James, B., Agarwal, P., Aggarwal, N., Cherian, L., Leurgans, S., Barnes, L., Bennett, D., & Schneider, J. (2021). MIND Diet, Common Brain Pathologies, and Cognition in Community-Dwelling Older Adults.. Journal of Alzheimer's disease : JAD. https://doi.org/10.3233/JAD-210107.

Doggui, R., Al-Jawaldeh, H., Ati, J., Barham, R., Nasreddine, L., Alqaoud, N., Aguenaou, H., Ammari, L., Jabbour, J., & Al-Jawaldeh, A. (2021). Meta-Analysis and Systematic Review of Micro- and Macro-Nutrient Intakes and Trajectories of Macro-Nutrient Supply in the Eastern Mediterranean Region. Nutrients, 13. https://doi.org/10.3390/nu13051515 .

Donev, R. (2014). Advances in protein chemistry and structural biology. Academic Press.

Duckney, P., Wong, H. K., Serrano, J., Yaradou, D., Oddos, T., & Stamatas, G. N. (2013). The role of the skin barrier in modulating the effects of common skin microbial species on the inflammation, differentiation and proliferation status of epidermal keratinocytes. BMC research notes, 6, 1-10.

Dwyer, J. (1988). Health aspects of vegetarian diets.. The American journal of clinical nutrition, 48 3 Suppl, 712-38 .

E. Blackburn & E. Epel, (2018). Telomer Etkisi. Doğan Kitap.

Eleftheriou, D., Benetou, V., Trichopoulou, A., Vecchia, C., & Bamia, C. (2018). Mediterranean diet and its components in relation to all-cause mortality: meta-analysis. British Journal of Nutrition, 120, 1081 - 1097.

El-Senousey, H., Chen, B., Wang, J., Atta, A., Mohamed, F., & Nie, Q. (2018). Effects of dietary vitamin C, vitamin E, and alpha‐lipoic acid supplementation on the antioxidant defense system and immune‐related gene expression in broilers exposed to oxidative stress by dexamethasone. Poultry Science, 97, 30–38. https://doi.org/10.3382/ps/pex298.

Eyre, S., Faxén-Irving, G., Attman, P. O., Evans, M., Windahl, K., Wegener, S., ... & Carrero, J. J. (2016). A practical approach to low protein diets in Sweden–45 years of clinical use. BMC nephrology, 17, 1-10.

Fabiani, R., Vella, N., & Rosignoli, P. (2021). Epigenetic modifications induced by olive oil and its phenolic compounds: A systematic review. Molecules, 26(2), 273.

Fairley, L., Lejri, I., Grimm, A., & Eckert, A. (2023). Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein. International Journal of Molecular Sciences, 24. https://doi.org/10.3390/ijms24065297.

Fanti, M., Mishra, A., Longo, V. D., & Brandhorst, S. (2021). Time-restricted eating, intermittent fasting, and fasting-mimicking diets in weight loss. Current obesity reports, 10, 70-80.

Feng, Q., Fan, S., Wu, Y., Zhou, D., Zhao, R., Liu, M., & Song, Y. (2018). Adherence to the dietary approaches to stop hypertension diet and risk of stroke. Medicine, 97.

Feng, S., Jacobsen, S., & Reik, W. (2010). Epigenetic Reprogramming in Plant and Animal Development. Science, 330, 622 - 627. https://doi.org/10.1126/science.1190614.

Fernandez, S. (2025, June 30). Aging: Chronic inflammation is associated with industrialized lifestyles. Science + Technology. https://www.news.ucsb.edu/2025/021464/chronic-inflammation-industrialized-lifestyles

Fontana, L., & Partridge, L. (2015). Promoting health and longevity through diet: from model organisms to humans. Cell, 161(1), 106-118.

Forman, H. J., Davies, K. J., & Ursini, F. (2014). How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo. Free Radical Biology and Medicine, 66, 24-35.

Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 69(Suppl_1), S4-S9.

Fu Q, Duan R, Sun Y, Li Q. Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics. Redox Biol. 2022 Jul;53:102352. doi: 10.1016/j.redox.2022.102352. Epub 2022 May 27. PMID: 35649312; PMCID: PMC9156818.

Fülöp, T., Larbi, A., & Witkowski, J. M. (2019). Human inflammaging. Gerontology, 65(5), 495-504.

Galano, A., Tan, D., & Reiter, R. (2018). Melatonin: A Versatile Protector against Oxidative DNA Damage. Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry, 23. https://doi.org/10.3390/molecules23030530.

García-Villalba, R., Giménez‐Bastida, J., Cortés-Martín, A., Ávila-Gálvez, M., Tomás-Barberán, F., Selma, M., Espín, J., & González‐Sarrías, A. (2022). Urolithins: a Comprehensive Update on their Metabolism, Bioactivity, and Associated Gut Microbiota. Molecular Nutrition & Food Research, 66. https://doi.org/10.1002/mnfr.202101019.

Gardner, C. D., Vadiveloo, M. K., Petersen, K. S., Anderson, C. A., Springfield, S., Van Horn, L., ... & American Heart Association Council on Lifestyle and Cardiometabolic Health. (2023). Popular dietary patterns: alignment with American Heart Association 2021 dietary guidance: a scientific statement from the American Heart Association. Circulation, 147(22), 1715-1730.

Gertz, M., Nguyen, G., Fischer, F., Suenkel, B., Schlicker, C., Fränzel, B., Tomaschewski, J., Aladini, F., Becker, C., Wolters, D., & Steegborn, C. (2012). A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol. PLoS ONE, 7. https://doi.org/10.1371/journal.pone.0049761.

Gill, Z., Nieuwoudt, M., & Ndifon, W. (2018). The Hayflick limit and age-related adaptive immune deficiency. Gerontology, 64(2), 135-139.

Gilsing, A. M., Weijenberg, M. P., Goldbohm, R. A., Dagnelie, P. C., van den Brandt, P. A., & Schouten, L. J. (2013). The Netherlands Cohort Study–Meat Investigation Cohort; a population-based cohort over-represented with vegetarians, pescetarians and low meat consumers. Nutrition journal, 12, 1-13.

Gindri, I., Ferrari, G., Pinto, L., Bicca, J., Santos, I., Dallacosta, D., & Roesler, C. (2023). Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review.. American journal of physiology. Endocrinology and metabolism. https://doi.org/10.1152/ajpendo.00242.2023.

Ginter, E. (2008). Vegetarian diets, chronic diseases and longevity.. Bratislavske lekarske listy, 109 10, 463-6 .

Glenn, A. J., Li, J., Lo, K., Jenkins, D. J. A., Boucher, B. A., Hanley, A. J., … & Sievenpiper, J. L. (2023). The portfolio diet and incident type 2 diabetes: Findings from the Women’s Health Initiative prospective cohort study. Diabetes Care, 46(1), 28–37. https://doi.org/10.2337/dc22-1029

Goodpaster, B. H., & Sparks, L. M. (2017). Metabolic flexibility in health and disease. Cell metabolism, 25(5), 1027-1036.

Greger, M. (2020). A whole food plant-based diet is effective for weight loss: The evidence. American journal of lifestyle medicine, 14(5), 500-510.

Gruver, A. L., Hudson, L. L., & Sempowski, G. (2007). Immunosenescence of ageing. The Journal of Pathology: A Journal of the Pathological Society of Great Britain and Ireland, 211(2), 144-156.

Grynkiewicz, G., & Demchuk, O. M. (2019). New perspectives for fisetin. Frontiers in chemistry, 7, 697.

Hannuksela, M. L., & Ellahham, S. (2001). Benefits and risks of sauna bathing. The American journal of medicine, 110(2), 118-126.

Harch PG, Andrews SR, Fogarty EF, Lucarini J, Van Meter KW. Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder. Med Gas Res. 2017 Oct 17;7(3):156-174. doi: 10.4103/2045-9912.215745. PMID: 29152209; PMCID: PMC5674654.

Harch PG. Systematic Review and Dosage Analysis: Hyperbaric Oxygen Therapy Efficacy in Mild Traumatic Brain Injury Persistent Postconcussion Syndrome. Front Neurol. 2022 Mar 17;13:815056. doi: 10.3389/fneur.2022.815056. PMID: 35370898; PMCID: PMC8968958.

Harris, C., Chowanadisai, W., Mishchuk, D., Satre, M., Slupsky, C., & Rucker, R. (2013). Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects.. The Journal of nutritional biochemistry, 24 12, 2076-84 . https://doi.org/10.1016/j.jnutbio.2013.07.008.

Hazzan, R., Ahmad, N., Slim, W., Mazen, E., & Neeman, Z. (2022). Hepatoprotective effect of combination of L-carnitine and magnesium-hydroxide in nonalcoholic fatty liver disease patients: a double-blinded randomized controlled pilot study.. European review for medical and pharmacological sciences, 26 20, 7522-7532 . https://doi.org/10.26355/eurrev_202210_30023.

He, K., Nukada, H., Urakami, T., & Murphy, M. (2003). Antioxidant and pro-oxidant properties of pyrroloquinoline quinone (PQQ): implications for its function in biological systems.. Biochemical pharmacology, 65 1, 67-74 . https://doi.org/10.1016/S0006-2952(02)01453-3.

Hernández-Arciga, U., Stamenkovic, C., Yadav, S., Nicoletti, C., Albalawy, W. N., Al Hammood, F., ... & Parkhitko, A. A. (2025). Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner. Science advances, 11(16), eads1532.

Hernández-Arciga, U., Stamenkovic, C., Yadav, S., Nicoletti, C., Albalawy, W. N., Al Hammood, F., ... & Parkhitko, A. A. (2025). Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner. Science advances, 11(16), eads1532.

Herpich, C., Müller-Werdan, U., & Norman, K. (2022). Role of plant-based diets in promoting health and longevity. Maturitas, 165, 47-51.

Hidaka, T., Fujii, K., Funahashi, I., Fukutomi, N., & Hosoe, K. (2008). Safety assessment of coenzyme Q10 (CoQ10). BioFactors, 32. https://doi.org/10.1002/biof.5520320124.

Hipp, M. S., Kasturi, P., & Hartl, F. U. (2019). The proteostasis network and its decline in ageing. Nature reviews Molecular cell biology, 20(7), 421-435.

https://drhyman.com/blog/2024/03/01/the-most-overlooked-cause-of-aging-and-disease-your-microbiome/?variation=B&_kx=PLA3mmHp0AZ1AjtNJYF3J8aCquitVKnJ0Ui4_srbrmE.HKMsXE

https://www.drfranklipman.com/post/4-ways-mtor-influences-how-well-you-age

https://www.drfranklipman.com/post/health-coach-tip---nose-breathing-vs-mouth-breathing-and-longevity

https://www.niehs.nih.gov/health/topics/science/microbiome

Hu, F. (2023). Diet strategies for promoting healthy aging and longevity: An epidemiological perspective.. Journal of internal medicine.

Hu, F. B. (2024). Diet strategies for promoting healthy aging and longevity: An epidemiological perspective. Journal of internal medicine, 295(4), 508-531.

Imai, S. I., & Guarente, L. (2014). NAD+ and sirtuins in aging and disease. Trends in cell biology, 24(8), 464-471.

Imenshahidi, M., & Hosseinzadeh, H. (2019). Berberine and barberry (Berberis vulgaris): A clinical review. Phytotherapy Research, 33, 504 - 523. https://doi.org/10.1002/ptr.6252.

Imran, M., Saeed, F., Gilani, S. A., Shariati, M. A., Imran, A., Afzaal, M., ... & Anjum, F. M. (2021). Fisetin: An anticancer perspective. Food science & nutrition, 9(1), 3-16.

Izadi, M., Sadri, N., Abdi, A., Serajian, S., Jalalei, D., & Tahmasebi, S. (2024). Epigenetic biomarkers in aging and longevity: Current and future application. Life sciences, 122842.

Jacobs, T. L., Epel, E. S., Lin, J., Blackburn, E. H., Wolkowitz, O. M., Bridwell, D. A., ... & Saron, C. D. (2011). Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology, 36(5), 664-681.

Jenkins, D. J. A., Jones, P. J., Lamarche, B., Kendall, C. W. C., Faulkner, D., … & Frohlich, J. (2011). Effect of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia. JAMA, 306(8), 831–839. https://doi.org/10.1001/jama.2011.1202

Jenkins, D. J. A., Josse, A. R., Wong, J. M. W., Nguyen, T. H., & Kendall, C. W. C. (2007). The portfolio diet for cardiovascular risk reduction. Current Atherosclerosis Reports, 9(6), 501–507. https://doi.org/10.1007/s11883-007-0067-7

Jenkins, D. J. A., Kendall, C. W. C., Marchie, A., Faulkner, D. A., Wong, J. M. W., de Souza, R., … & Connelly, P. W. (2005). Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants. American Journal of Clinical Nutrition, 81(2), 380–387.https://doi.org/10.1093/ajcn/81.2.380

Ji, S.T.; Kim, Y.J.; Jung, S.Y.; Kim, D.Y.; Kang, S.; Park, J.H.; Jang, W.B.; Ha, J.; Yun, J.; Kwon, S.M. Oleuropein Attenuates Hydrogen Peroxide-Induced Autophagic Cell Death in Human Adipose-Derived Stem Cells. Biochem. Biophys. Res. Commun.

Jungmann M, Vencatachellum S, Van Ryckeghem D, Vögele C. Effects of Cold Stimulation on Cardiac-Vagal Activation in Healthy Participants: Randomized Controlled Trial. JMIR Form Res. 2018 Oct 9;2(2):e10257. doi: 10.2196/10257. PMID: 30684416; PMCID: PMC6334714.

Kamal, N. S. M., Safuan, S., Shamsuddin, S., & Foroozandeh, P. (2020). Aging of the cells: Insight into cellular senescence and detection Methods. European journal of cell biology, 99(6), 151108.

Kaplan, H., Hill, K., Lancaster, J., & Hurtado, A. M. (2000). A theory of human life history evolution: Diet, intelligence, and longevity. Evolutionary Anthropology: Issues, News, and Reviews: Issues, News, and Reviews, 9(4), 156-185.

Kaushik, S., & Cuervo, A. M. (2015). Proteostasis and aging. Nature medicine, 21(12), 1406-1415.

Kim, K., Nam, Y., Kim, H., Hayes, A., & Lee, B. (2014). α-Linolenic acid: nutraceutical, pharmacological and toxicological evaluation.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 70, 163-78 . https://doi.org/10.1016/j.fct.2014.05.009.

Knezevic, E., Nenic, K., Milanovic, V., & Knezevic, N. N. (2023). The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders. Cells, 12(23), 2726.

Kojić, D., Spremo, J., Đorđievski, S., Čelić, T., Vukašinović, E., Pihler, I., & Purać, J. (2024). Spermidine supplementation in honey bees: Autophagy and epigenetic modifications. Plos one, 19(7), e0306430.

Kordinas, V., Ioannidis, A., & Chatzipanagiotou, S. (2016). The telomere/telomerase system in chronic inflammatory diseases. Cause or effect?. Genes, 7(9), 60.

Kuerec, A. H., Wang, W., Yi, L., Tao, R., Lin, Z., Vaidya, A., ... & Maier, A. B. (2024). Towards personalized nicotinamide mononucleotide (NMN) supplementation: nicotinamide adenine dinucleotide (NAD) concentration. Mechanisms of Ageing and Development, 218, 111917.

Kumar, A., , E., Chopra, K., Mukherjee, M., Pottabathini, R., & Dhull, D. (2015). Current knowledge and pharmacological profile of berberine: An update.. European journal of pharmacology, 761, 288-97 . https://doi.org/10.1016/j.ejphar.2015.05.068.

Kunutsor, S. K., Laukkanen, T., & Laukkanen, J. A. (2017). Sauna bathing reduces the risk of respiratory diseases: a long-term prospective cohort study. European journal of epidemiology, 32, 1107-1111.

Laafi, J., Homedan, C., Jacques, C., Gueguen, N., Schmitt, C., Puy, H., Reynier, P., Martínez, M., & Malthiéry, Y. (2014). Pro-oxidant effect of ALA is implicated in mitochondrial dysfunction of HepG2 cells.. Biochimie, 106, 157-66 . https://doi.org/10.1016/j.biochi.2014.08.014.

Labbadia, J., & Morimoto, R. I. (2014). Proteostasis and longevity: when does aging really begin?. F1000prime reports, 6.

Labbadia, J., & Morimoto, R. I. (2015). The biology of proteostasis in aging and disease. Annual review of biochemistry, 84(1), 435-464.

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., ... & Auwerx, J. (2006). Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell, 127(6), 1109-1122.

Laplante, M., & Sabatini, D. M. (2012). mTOR signaling in growth control and disease. cell, 149(2), 274-293.

Last, N., Tufts, E., & Auger, L. (2017). The Effects of Meditation on Grey Matter Atrophy and Neurodegeneration: A Systematic Review.. Journal of Alzheimer's disease : JAD, 56 1, 275-286 . https://doi.org/10.3233/JAD-160899.

Latham, L., Wang, C., Patterson, T., Slikker, W., & Liu, F. (2021). Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity.. Chemical research in toxicology. https://doi.org/10.1021/acs.chemrestox.0c00479.

Laukkanen, J. A., Laukkanen, T., & Kunutsor, S. K. (2018, August). Cardiovascular and other health benefits of sauna bathing: a review of the evidence. In Mayo clinic proceedings (Vol. 93, No. 8, pp. 1111-1121). Elsevier.

Lawler, J., Barnes, W., Wu, G., Song, W., & Demaree, S. (2002). Direct antioxidant properties of creatine.. Biochemical and biophysical research communications, 290 1, 47-52 . https://doi.org/10.1006/BBRC.2001.6164.

Le Couteur, D. G., Solon-Biet, S., Cogger, V. C., Mitchell, S. J., Senior, A., de Cabo, R., ... & Simpson, S. J. (2016). The impact of low-protein high-carbohydrate diets on aging and lifespan. Cellular and Molecular Life Sciences, 73, 1237-1252.

Leblanc, J., & Pouliot, M. (1964). Importance of noradrenaline in cold adaptation. American Journal of Physiology-Legacy Content, 207(4), 853-856.

Li, H.; He, H.; Liu, C.; Akanji, T.; Gutkowski, J.; Li, R.; Ma, H.; Wan, Y.; Wu, P.; Li, D.; et al. Dietary Polyphenol Oleuropein and Its Metabolite Hydroxytyrosol Are Moderate Skin Permeable Elastase and Collagenase Inhibitors with Synergistic Cellular Antioxidant Effects in Human Skin Fibroblasts. Int. J. Food Sci. Nutr. 2022, 73, 460–470.

Li, Y., Wei, G., & Chen, J. (2004). Glutathione: a review on biotechnological production. Applied Microbiology and Biotechnology, 66, 233-242. https://doi.org/10.1007/s00253-004-1751-y.

Li, Y., Yao, J., Han, C., Yang, J., Chaudhry, M. T., Wang, S., ... & Yin, Y. (2016). Quercetin, inflammation and immunity. Nutrients, 8(3), 167.

Linowiecka, K., Slominski, A., Reiter, R., Böhm, M., Steinbrink, K., Paus, R., & Kleszczyński, K. (2023). Melatonin: A Potential Regulator of DNA Methylation. Antioxidants, 12. https://doi.org/10.3390/antiox12061155.

Liu, S., Zeng, M., Wan, W., Huang, M., Li, X., Xie, Z., ... & Cai, Y. (2023). The health‐promoting effects and the mechanism of intermittent fasting. Journal of diabetes research, 2023(1), 4038546.

Longo, V. D., & Mattson, M. P. (2014). Fasting: molecular mechanisms and clinical applications. Cell metabolism, 19(2), 181-192.

López-Gil, L., Pascual-Ahuir, A., & Proft, M. (2023). Genomic instability and epigenetic changes during aging. International Journal of Molecular Sciences, 24(18), 14279.

Mach, F., Baigent, C., Catapano, A. L., Koskinas, K. C., Casula, M., Badimon, L., ... & Wiklund, O. (2020). 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS). European heart journal, 41(1), 111-188.

Madeo, F., Eisenberg, T., Büttner, S., Ruckenstuhl, C., & Kroemer, G. (2010). Spermidine: A novel autophagy inducer and longevity elixir. Autophagy, 6, 14 - 160 - 162. https://doi.org/10.4161/auto.6.1.10600.

Maraslis, F. T., Jacobsen-Pereira, C. H., Parisotto, E. B., Pinheiro, K., Franco, M. J., Galluzzo, R. N., ... & Maluf, S. W. (2024). Genomic instability and oxidative stress markers in pregnant women presenting fetal malformation. Gene Reports, 36, 101931.

Marin, M. F., Lord, C., Andrews, J., Juster, R. P., Sindi, S., Arsenault-Lapierre, G., ... & Lupien, S. J. (2011). Chronic stress, cognitive functioning and mental health. Neurobiology of learning and memory, 96(4), 583-595.

Martin, M. S., Dynesen, A. W., Petersen, B., Petersen, I. L., Duque Estrada, P., & Aaslyng, M. D. (2024). The satiating effect of extruded plant protein compared with native plant and meat protein in a ragú “bolognaise” meal: A randomized cross-over study. Nutrients, 16(19), 3407.

Mathur, M. B., Epel, E., Kind, S., Desai, M., Parks, C. G., Sandler, D. P., & Khazeni, N. (2016). Perceived stress and telomere length: A systematic review, meta-analysis, and methodologic considerations for advancing the field. Brain, behavior, and immunity, 54, 158-169.

Mendelsohn, A. R., & Larrick, J. W. (2015). Stem cell depletion by global disorganization of the H3K9me3 epigenetic marker in aging. Rejuvenation Research, 18(4), 371-375.

Mindful Eating 101 — A Beginner’s Guide (healthline.com)

Mindfulness Activities: Easy Mindfulness Exercises for Any Age (healthline.com)

Mindfulness for Kids: 5 Strategies (healthline.com)

Minich, D., & Brown, B. (2019). A Review of Dietary (Phyto)Nutrients for Glutathione Support. Nutrients, 11. https://doi.org/10.3390/nu11092073.

Mizushima, N. (2007). Autophagy: process and function. Genes & development, 21(22), 2861-2873.

Mocanu, C. A., Simionescu, T. P., Mocanu, A. E., & Garneata, L. (2021). Plant-based versus animal-based low protein diets in the management of chronic kidney disease. Nutrients, 13(11), 3721.

Morimitsu, Y., Nakagawa, Y., Hayashi, K., Fujii, H., Kumagai, T., Nakamura, Y., ... & Uchida, K. (2002). A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. Journal of Biological Chemistry, 277(5), 3456-3463.

Morselli, E., Maiuri, M. C., Markaki, M., Megalou, E., Pasparaki, A., Palikaras, K., ... & Kroemer, G. (2010). Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell death & disease, 1(1), e10-e10.

Mukherjee, S.; Mishra, A.K.; Peer, G.D.G.; Bagabir, S.A.; Haque, S.; Pandey, R.P.; Raj, V.S.; Jain, N.; Pandey, A.; Kar, S.K. The Interplay of the Unfolded Protein Response in Neurodegenerative Diseases: A Therapeutic Role of Curcumin. Front. Aging Neurosci. 2021, 13, 767493.

Muscogiuri, G., Barrea, L., Laudisio, D., Pugliese, G., Salzano, C., Savastano, S., & Colao, A. (2019). The management of very low-calorie ketogenic diet in obesity outpatient clinic: a practical guide. Journal of translational medicine, 17(1), 356.

Nabuurs, C., Choe, C., Veltien, A., Kan, H., Loon, L., Rodenburg, R., Matschke, J., Wieringa, B., Kemp, G., Isbrandt, D., & Heerschap, A. (2013). Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake. The Journal of Physiology, 591. https://doi.org/10.1113/jphysiol.2012.241760.

Napoleão, A., Fernandes, L., Miranda, C., & Marum, A. P. (2021). Effects of calorie restriction on health span and insulin resistance: Classic calorie restriction diet vs. ketosis-inducing diet. Nutrients, 13(4), 1302.

Narayanankutty, A., Jdevagiri, J., & Narayanankutty, V. (2019). Glutathione, an antioxidant tripeptide: Dual roles in Carcinogenesis and Chemoprevention.. Current protein & peptide science. https://doi.org/10.2174/1389203720666190206130003.

Negri, A.; Naponelli, V.; Rizzi, F.; Bettuzzi, S. Molecular Targets of Epigallocatechin-Gallate (EGCG): A Special Focus on Signal Transduction and Cancer. Nutrients 2018, 10, 1936.

Norman, K., & Klaus, S. (2019). Veganism, aging and longevity: new insight into old concepts.. Current Opinion in Clinical Nutrition & Metabolic Care.

Nydegger, U. E., Luginbühl, M., & Risch, M. (2015). The aging human recipient of transfusion products. Transfusion and Apheresis Science, 52(3), 290-294.9.

Owen, K., Jit, H., Maxwell, C., Nelssen, J., Goodband, R., Tokach, M., Tremblay, G., & Koo, S. (2001). Dietary L-carnitine suppresses mitochondrial branched-chain keto acid dehydrogenase activity and enhances protein accretion and carcass characteristics of swine.. Journal of animal science, 79 12, 3104-12 . https://doi.org/10.2527/2001.79123104X.

Pal, A., Naika, M., Khanum, F., & Bawa, A. (2011). In-vitro studies on the antioxidant assay profiling of Withania somnifera L. (Ashwagandha) Dunal root: Part 1. Polymer Journal, 3, 47-55. https://doi.org/10.5530/PJ.2011.20.10.

Pal, A., Naika, M., Khanum, F., & Bawa, A. (2011). In-vitro studies on the antioxidant assay profiling of Withania somnifera L. (Ashwagandha) Dunal root: Part 1. Polymer Journal, 3, 47-55. https://doi.org/10.5530/PJ.2011.20.10.

Palmer, B. F., & Clegg, D. J. (2022, April). Metabolic flexibility and its impact on health outcomes. In Mayo Clinic Proceedings (Vol. 97, No. 4, pp. 761-776). Elsevier.

Panda S. (2016). Circadian physiology of metabolism. Science (New York, N.Y.), 354(6315), 1008–1015. https://doi.org/10.1126/science.aah4967

Patrick, R. P., & Johnson, T. L. (2021). Sauna use as a lifestyle practice to extend healthspan. Experimental gerontology, 154, 111509.

Pereira, C. D., Guimarães, C., Ribeiro, V. S., Vaz, D. C., & Martins, M. J. (2024). Low-Protein Diets, Malnutrition, and Bone Metabolism in Chronic Kidney Disease. Nutrients, 16(18), 3098.

Pérez-López, F., Chedraui, P., Haya, J., & Cuadros, J. (2009). Effects of the Mediterranean diet on longevity and age-related morbid conditions.. Maturitas, 64 2, 67-79 .

Pes, G. M., Dore, M. P., Tsofliou, F., & Poulain, M. (2022). Diet and longevity in the Blue Zones: A set-and-forget issue?. Maturitas, 164, 31-37.

Pes, G. M., Dore, M. P., Tsofliou, F., & Poulain, M. (2022). Diet and longevity in the Blue Zones: A set-and-forget issue?. Maturitas, 164, 31-37.

Pomatto, L. C., & Davies, K. J. (2018). Adaptive homeostasis and the free radical theory of ageing. Free Radical Biology and Medicine, 124, 420-430.

Qi, T., Xu, F., Yan, X., Li, S., & Li, H. (2016). Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway.. International journal of molecular medicine, 37 1, 182-8 . https://doi.org/10.3892/ijmm.2015.2396.

Ratriyanto, A., & Mosenthin, R. (2018). Osmoregulatory function of betaine in alleviating heat stress in poultry. Journal of Animal Physiology and Animal Nutrition, 102, 1634–1650. https://doi.org/10.1111/jpn.12990.

Rattan, S. (2008). Hormesis in aging. Ageing Research Reviews, 7, 63-78. https://doi.org/10.1016/j.arr.2007.03.002.

Rattan, S. I. (2006). Theories of biological aging: genes, proteins, and free radicals. Free radical research, 40(12), 1230-1238.

Razis, A., Iori, R., & Ioannides, C. (2011). The natural chemopreventive phytochemical R‐sulforaphane is a far more potent inducer of the carcinogen‐detoxifying enzyme systems in rat liver and lung than the S‐isomer. International Journal of Cancer, 128. https://doi.org/10.1002/ijc.25620.

Reddy, B. L., Reddy, V. S., & Saier Jr, M. H. (2024). Health benefits of intermittent fasting. Microbial Physiology, 34(1), 142-152.

Revesz, D., Milaneschi, Y., Terpstra, E. M., & Penninx, B. W. (2016). Baseline biopsychosocial determinants of telomere length and 6-year attrition rate. Psychoneuroendocrinology, 67, 153-162.

Rudolph, K. L., Chang, S., Lee, H. W., Blasco, M., Gottlieb, G. J., Greider, C., & DePinho, R. A. (1999). Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell, 96(5), 701-712.

Ryu, D., Mouchiroud, L., Andreux, P., Katsyuba, E., Moullan, N., Nicolet-dit-Félix, A., Williams, E., Jha, P., Sasso, G., Huzard, D., Aebischer, P., Sandi, C., Rinsch, C., & Auwerx, J. (2016). Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nature Medicine, 22, 879-888. https://doi.org/10.1038/nm.4132.

Satarker, S., Wilson, J., Kolathur, K. K., Mudgal, J., Lewis, S. A., Arora, D., & Nampoothiri, M. (2024). Spermidine as an epigenetic regulator of autophagy in neurodegenerative disorders. European Journal of Pharmacology, 176823.

Saxton, R. A., & Sabatini, D. M. (2017). mTOR Signaling in Growth, Metabolism, and Disease. Cell, 168(6), 960–976. https://doi.org/10.1016/j.cell.2017.02.004

Selye, H. (1975). Confusion and controversy in the stress field. Journal of human stress, 1(2), 37-44.

Sen, P., Shah, P. P., Nativio, R., & Berger, S. L. (2016). Epigenetic mechanisms of longevity and aging. Cell, 166(4), 822-839.

Shaito, A., Posadino, A., Younes, N., Hasan, H., Halabi, S., Alhababi, D., Al-Mohannadi, A., Abdel-Rahman, W., Eid, A., Nasrallah, G., & Pintus, G. (2020). Potential Adverse Effects of Resveratrol: A Literature Review. International Journal of Molecular Sciences, 21. https://doi.org/10.3390/ijms21062084.

Singh, A., Andreux, P., Blanco, W., Auwerx, J., & Rinsch, C. (2019). Urolithin A, a Gut Microbiome Derived Metabolite Improves Mitochondrial and Cellular Health: Results from a Randomized, Placebo-controlled, Double-blind Clinical Trial (FS09-06-19). Current Developments in Nutrition. https://doi.org/10.1093/cdn/nzz044.fs09-06-19.

Soda, K. (2022). Overview of Polyamines as Nutrients for Human Healthy Long Life and Effect of Increased Polyamine Intake on DNA Methylation. Cells, 11. https://doi.org/10.3390/cells11010164.

Sorensen MD, Arlinghaus KR, Ledoux TA, Johnston CA. Integrating Mindfulness Into Eating Behaviors. Am J Lifestyle Med. 2019 Aug 15;13(6):537-539. doi: 10.1177/1559827619867626. PMID: 31662716; PMCID: PMC6796218.

Şimşek, D. (2020). Birim. Nemesis Yayınları.

Tan, D., Manchester, L., Esteban-Zubero, E., Zhou, Z., & Reiter, R. (2015). Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism. Molecules, 20, 18886 - 18906. https://doi.org/10.3390/molecules201018886.

Tang, J.; Zheng, J.S.; Fang, L.; Jin, Y.; Cai, W.; Li, D. Tea Consumption and Mortality of All Cancers, CVD and All Causes: A Meta-Analysis of Eighteen Prospective Cohort Studies. Br. J. Nutr. 2015, 114, 673–683.

Tavenier, J., Nehlin, J. O., Houlind, M. B., Rasmussen, L. J., Tchkonia, T., Kirkland, J. L., ... & Rasmussen, L. J. H. (2024). Fisetin as a senotherapeutic agent: Evidence and perspectives for age-related diseases. Mechanisms of Ageing and Development, 222, 111995.

Thejass, P., & Kuttan,, G. (2007). Immunomodulatory activity of Sulforaphane, a naturally occurring isothiocyanate from broccoli (Brassica oleracea).. Phytomedicine : international journal of phytotherapy and phytopharmacology, 14 7-8, 538-45 . https://doi.org/10.1016/J.PHYMED.2006.09.013.

Thoppil H and Riabowol K (2020) Senolytics: A Translational Bridge Between Cellular Senescence and Organismal Aging. Front. Cell Dev. Biol. 7:367. doi: 10.3389/fcell.2019.00367

Tolahunase, M., Sagar, R., Faiq, M., & Dada, R. (2018). Yoga- and meditation-based lifestyle intervention increases neuroplasticity and reduces severity of major depressive disorder: A randomized controlled trial.. Restorative neurology and neuroscience, 36 3, 423-442 . https://doi.org/10.3233/RNN-170810.

Tolkovsky, A. M. (2009). Mitophagy. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1793(9), 1508-1515.

Trautwein, E. A., & McKay, S. (2020). The role of specific components of a plant-based diet in management of dyslipidemia and the impact on cardiovascular risk. Nutrients, 12(9), 2671.

Tsukakoshi, K., Yoshida, W., Kobayashi, M., Kobayashi, N., Kim, J., Kaku, T., Iguchi, T., Nagasawa, K., Asano, R., Ikebukuro, K., & Sode, K. (2018). Esterification of PQQ Enhances Blood-Brain Barrier Permeability and Inhibitory Activity against Amyloidogenic Protein Fibril Formation.. ACS chemical neuroscience, 9 12, 2898-2903 . https://doi.org/10.1021/acschemneuro.8b00355.

Vosselman MJ, Vijgen GH, Kingma BR, Brans B, van Marken Lichtenbelt WD. Frequent extreme cold exposure and brown fat and cold-induced thermogenesis: a study in a monozygotic twin. PLoS One. 2014 Jul 11;9(7):e101653. doi: 10.1371/journal.pone.0101653. PMID: 25014028; PMCID: PMC4094425.

Walker, M. A., & Tian, R. (2018). NAD (H) in mitochondrial energy transduction: implications for health and disease. Current opinion in physiology, 3, 101-109.

Wall, B., Stephens, F., Constantin-Teodosiu, D., Marimuthu, K., Macdonald, I., & Greenhaff, P. (2011). Chronic oral ingestion of l‐carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. The Journal of Physiology, 589. https://doi.org/10.1113/jphysiol.2010.201343.

Wang, W., & Ballatori, N. (1998). Endogenous glutathione conjugates: occurrence and biological functions.. Pharmacological reviews, 50 3, 335-56 .

Wickens, A. P. (2001). Ageing and the free radical theory. Respiration physiology, 128(3), 379-391.

Willett, W., Rockström, J., Loken, B., Springmann, M., Lang, T., Vermeulen, S., ... & Murray, C. J. (2019). Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems. The lancet, 393(10170), 447-492.

Xie, S., Zhou, W., Tian, L., Niu, J., & Liu, Y. (2016). Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, anti-oxidative and immune ability of Nile tilapia, Oreochromis niloticus.. Fish & shellfish immunology, 55, 233-41 . https://doi.org/10.1016/j.fsi.2016.05.033.

Xue, S. W., Tang, Y. Y., Tang, R., & Posner, M. I. (2014). Short-term meditation induces changes in brain resting EEG theta networks. Brain and cognition, 87, 1-6.

Yadawa, A. K., et al. (2023). Berberine may provide redox homeostasis during aging in rats. Z Naturforsch C Journal of Biosciences, 78(7–8), 307–315. https://doi.org/10.1515/znc-2022-0213

Yan, H., Ren, J., & Liu, G. H. (2023). Fecal microbiota transplantation: a new strategy to delay aging. hLife, 1(1), 8-11.

Yang, Q., & Guan, K. L. (2007). Expanding mTOR signaling. Cell research, 17(8), 666-681.

Yankouskaya A, Williamson R, Stacey C, Totman JJ, Massey H. Short-Term Head-Out Whole-Body Cold-Water Immersion Facilitates Positive Affect and Increases Interaction between Large-Scale Brain Networks. Biology (Basel). 2023 Jan 29;12(2):211. doi: 10.3390/biology12020211. PMID: 36829490; PMCID: PMC9953392.

Yao, J., et al. (2023). The efficacy and mechanism of berberine in improving aging-related cognitive dysfunction: A study based on network pharmacology. Frontiers in Neuroscience, 17, 109318. https://doi.org/10.3389/fnins.2023.109318

Yoon, M. S. (2016). The emerging role of branched-chain amino acids in insulin resistance and metabolism. Nutrients, 8(7), 405.

Zhang, B., Lin, M., Yu, C., Li, J., Zhang, L., Zhou, P., Yang, W., Gao, F., & Zhou, G. (2016). Alanyl-glutamine supplementation regulates mTOR and ubiquitin proteasome proteolysis signaling pathways in piglets.. Nutrition, 32 10, 1123-31 . https://doi.org/10.1016/j.nut.2016.02.023.

Zhang,Z.;Zhao,H.;Wang,A. Oleuropein Alleviates Gestational Diabetes Mellitus by Activating AMPK Signaling. Endocr. Connect. 2021,

Zhou, Y., Hu, G., & Wang, M. C. (2021). Host and microbiota metabolic signals in aging and longevity. Nature Chemical Biology, 17(10), 1027-1036.

Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., … & Kirkland, J. L. (2015). The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell, 14(4), 644–658. https://doi.org/10.1111/acel.12344

Zhu, Yi et al. “The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs.” Aging cell vol. 14,4 (2015): 644-58. doi:10.1111/acel.12344

Zia, A.; Farkhondeh, T.; Pourbagher-Shahri, A.M.; Samarghandian, S. The Role of Curcumin in Aging and Senescence: Molecular Mechanisms. Biomed. Pharmacother. 2021, 134, 111119.

Zong, Y., Li, H., Liao, P., Chen, L., Pan, Y., Zheng, Y., ... & Gao, J. (2024). Mitochondrial dysfunction: mechanisms and advances in therapy. Signal Transduction and Targeted Therapy, 9(1), 124.