Otoimmun Tiroid Hastalıklarında Mikrobiyotanın Rolü

Luty J, Ruckemann-Dziurdzińska K, Witkowski JM, et al. Immunological aspects of autoimmune thyroid disease–Complex interplay between cells and cytokines. Cytokine. 2019;116:128-33.

Lee HJ, Li CW, Hammerstad SS, et al. Immunogenetics of autoimmune thyroid diseases: a comprehensive review. Journal of autoimmunity. 2015;64:82-90.

Franco J-S, Amaya-Amaya J, Anaya J-M. Thyroid disease and autoimmune diseases. Autoimmunity: From Bench to Bedside [Internet]: El Rosario University Press; 2013.

Docimo G, Cangiano A, Romano RM, et al. The human microbiota in endocrinology: implications for pathophysiology, treatment, and prognosis in thyroid diseases. Frontiers in endocrinology. 2020;11:586529.

Köhling HL, Plummer SF, Marchesi JR, et al. The microbiota and autoimmunity: Their role in thyroid autoimmune diseases. Clinical immunology. 2017;183:63-74.

Yan K, Sun X, Fan C, et al. Unveiling the Role of Gut Microbiota and Metabolites in Autoimmune Thyroid Diseases: Emerging Perspectives. International Journal of Molecular Sciences. 2024;25(20):10918.

Alkader DAA, Asadi N, Solangi U, et al. Exploring the role of gut microbiota in autoimmune thyroid disorders: a systematic review and meta-analysis. Frontiers in Endocrinology. 2023;14:1238146.

Stojanov S, Berlec A, Štrukelj B. The influence of probiotics on the firmicutes/bacteroidetes ratio in the treatment of obesity and inflammatory bowel disease. Microorganisms. 2020;8(11):1715.

Magne F, Gotteland M, Gauthier L, et al. The firmicutes/bacteroidetes ratio: a relevant marker of gut dysbiosis in obese patients? Nutrients. 2020;12(5):1474.

El‐Zawawy HT, Ahmed SM, El‐Attar EA, et al. Study of gut microbiome in Egyptian patients with autoimmune thyroid diseases. International Journal of Clinical Practice. 2021;75(5):e14038.

Gong B, Wang C, Meng F, et al. Association between gut microbiota and autoimmune thyroid disease: a systematic review and meta-analysis. Frontiers in endocrinology. 2021;12:774362.

Moshkelgosha S, Verhasselt HL, Masetti G, et al. Modulating gut microbiota in a mouse model of Graves ‘orbitopathy. Microbiome, 2021, 9: 1-20.

Liu S, An Y, Cao B, et al. The composition of gut microbiota in patients bearing Hashimoto’s thyroiditis with euthyroidism and hypothyroidism. International journal of endocrinology. 2020;2020(1):5036959.

Zhang Q, Tong B, Xie Z, et al. Changes in the gut microbiota of patients with Graves' orbitopathy according to severity grade. Clinical & Experimental Ophthalmology. 2023;51(8):808-21.

Shi T-T, Xin Z, Hua L, et al. Alterations in the intestinal microbiota of patients with severe and active Graves’ orbitopathy: a cross-sectional study. Journal of Endocrinological Investigation. 2019;42:967-78.

Shi T-T, Xin Z, Hua L, et al. Comparative assessment of gut microbial composition and function in patients with Graves’ disease and Graves’ orbitopathy. Journal of Endocrinological Investigation. 2021;44:297-310.

Yang M, Sun B, Li J, Yang B, et al. Alteration of the intestinal flora may participate in the development of Graves’ disease: a study conducted among the Han population in southwest China. Endocrine connections. 2019;8(7):822-8.

Liu J, Qin X, Lin B, Cui J, et al. Analysis of gut microbiota diversity in Hashimoto’s thyroiditis patients. BMC microbiology. 2022;22(1):318.

Dong T, Zhao F, Yuan K, Zhu X, Wang N, Xia F, et al. Association between serum thyroid-stimulating hormone levels and salivary microbiome shifts. Frontiers in Cellular and Infection Microbiology. 2021;11:603291.

Jiang W, Lu G, Gao D, et al. The relationships between the gut microbiota and its metabolites with thyroid diseases. Frontiers in endocrinology. 2022;13:943408.

Chang S-C, Lin S-F, Chen S-T, et al. Alterations of gut microbiota in patients with Graves’ disease. Frontiers in cellular and infection microbiology. 2021;11:663131.

Küçükemre Aydın B, Yıldız M, et al. Children with Hashimoto's thyroiditis have increased intestinal permeability: results of a pilot study. Journal of Clinical Research in Pediatric Endocrinology.2020.

El Asmar R, Panigrahi P, Bamford P, et al. Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure. Gastroenterology. 2002;123(5):1607-15.

Fasano A. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. F1000Research. 2020;9:F1000 Faculty Rev-69.

Cayres LCdF, de Salis LVV, Rodrigues GSP, et al. Detection of alterations in the gut microbiota and intestinal permeability in patients with Hashimoto thyroiditis. Frontiers in immunology. 2021;12:579140.

Halawa MR, Ahmed IZ, Eid YM, et al. Study of Leaky Gut syndrome and its Correlation to Hashimoto’s Thyroid Disease with Respect to Antibodies Titre. QJM: An International Journal of Medicine. 2024;117(Supplement_2):hcae175. 424.

Kiseleva E, Mikhailopulo K, Sviridov O, et al. The role of components of Bifidobacterium and Lactobacillus in pathogenesis and serologic diagnosis of autoimmune thyroid diseases. Beneficial microbes. 2011;2(2):139-54.

Su X, Yin X, Liu Y, Yan X, et al. Gut dysbiosis contributes to the imbalance of Treg and Th17 cells in Graves’ disease patients by propionic acid. The Journal of Clinical Endocrinology & Metabolism. 2020;105(11):3526-47.

Chen J, Wang W, Guo Z, et al. Associations between gut microbiota and thyroidal function status in Chinese patients with Graves’ disease. Journal of Endocrinological Investigation. 2021:1-14.

Sawicka-Gutaj N, Gruszczyński D, Zawalna N, et al. Microbiota alterations in patients with autoimmune thyroid diseases: a systematic review. International Journal of Molecular Sciences. 2022;23(21):13450.

Klasson CL, Sadhir S, Pontzer H. Daily physical activity is negatively associated with thyroid hormone levels, inflammation, and immune system markers among men and women in the NHANES dataset. PLoS One. 2022;17(7):e0270221.

Fang L, Ning J. Recent advances in gut microbiota and thyroid disease: pathogenesis and therapeutics in autoimmune, neoplastic, and nodular conditions. Frontiers in Cellular and Infection Microbiology. 2024;14:1465928.

Zhang S, Zhao X, Wang X, et al. Gut microecology may be involved in the pathogenesis of hashimoto thyroiditis by reducing production of hydrogen sulfide. The Journal of Clinical Endocrinology & Metabolism. 2024;109(3):792-801.

Luty J, Ruckemann-Dziurdzińska K, Witkowski JM, et al. Immunological aspects of autoimmune thyroid disease–Complex interplay between cells and cytokines. Cytokine. 2019;116:128-33.

Lee HJ, Li CW, Hammerstad SS, et al. Immunogenetics of autoimmune thyroid diseases: a comprehensive review. Journal of autoimmunity. 2015;64:82-90.

Franco J-S, Amaya-Amaya J, Anaya J-M. Thyroid disease and autoimmune diseases. Autoimmunity: From Bench to Bedside [Internet]: El Rosario University Press; 2013.

Docimo G, Cangiano A, Romano RM, et al. The human microbiota in endocrinology: implications for pathophysiology, treatment, and prognosis in thyroid diseases. Frontiers in endocrinology. 2020;11:586529.

Köhling HL, Plummer SF, Marchesi JR, et al. The microbiota and autoimmunity: Their role in thyroid autoimmune diseases. Clinical immunology. 2017;183:63-74.

Yan K, Sun X, Fan C, et al. Unveiling the Role of Gut Microbiota and Metabolites in Autoimmune Thyroid Diseases: Emerging Perspectives. International Journal of Molecular Sciences. 2024;25(20):10918.

Alkader DAA, Asadi N, Solangi U, et al. Exploring the role of gut microbiota in autoimmune thyroid disorders: a systematic review and meta-analysis. Frontiers in Endocrinology. 2023;14:1238146.

Stojanov S, Berlec A, Štrukelj B. The influence of probiotics on the firmicutes/bacteroidetes ratio in the treatment of obesity and inflammatory bowel disease. Microorganisms. 2020;8(11):1715.

Magne F, Gotteland M, Gauthier L, et al. The firmicutes/bacteroidetes ratio: a relevant marker of gut dysbiosis in obese patients? Nutrients. 2020;12(5):1474.

El‐Zawawy HT, Ahmed SM, El‐Attar EA, et al. Study of gut microbiome in Egyptian patients with autoimmune thyroid diseases. International Journal of Clinical Practice. 2021;75(5):e14038.

Gong B, Wang C, Meng F, et al. Association between gut microbiota and autoimmune thyroid disease: a systematic review and meta-analysis. Frontiers in endocrinology. 2021;12:774362.

Moshkelgosha S, Verhasselt HL, Masetti G, et al. Modulating gut microbiota in a mouse model of Graves ‘orbitopathy. Microbiome, 2021, 9: 1-20.

Liu S, An Y, Cao B, et al. The composition of gut microbiota in patients bearing Hashimoto’s thyroiditis with euthyroidism and hypothyroidism. International journal of endocrinology. 2020;2020(1):5036959.

Zhang Q, Tong B, Xie Z, et al. Changes in the gut microbiota of patients with Graves' orbitopathy according to severity grade. Clinical & Experimental Ophthalmology. 2023;51(8):808-21.

Shi T-T, Xin Z, Hua L, et al. Alterations in the intestinal microbiota of patients with severe and active Graves’ orbitopathy: a cross-sectional study. Journal of Endocrinological Investigation. 2019;42:967-78.

Shi T-T, Xin Z, Hua L, et al. Comparative assessment of gut microbial composition and function in patients with Graves’ disease and Graves’ orbitopathy. Journal of Endocrinological Investigation. 2021;44:297-310.

Yang M, Sun B, Li J, Yang B, et al. Alteration of the intestinal flora may participate in the development of Graves’ disease: a study conducted among the Han population in southwest China. Endocrine connections. 2019;8(7):822-8.

Liu J, Qin X, Lin B, Cui J, et al. Analysis of gut microbiota diversity in Hashimoto’s thyroiditis patients. BMC microbiology. 2022;22(1):318.

Dong T, Zhao F, Yuan K, Zhu X, Wang N, Xia F, et al. Association between serum thyroid-stimulating hormone levels and salivary microbiome shifts. Frontiers in Cellular and Infection Microbiology. 2021;11:603291.

Jiang W, Lu G, Gao D, et al. The relationships between the gut microbiota and its metabolites with thyroid diseases. Frontiers in endocrinology. 2022;13:943408.

Chang S-C, Lin S-F, Chen S-T, et al. Alterations of gut microbiota in patients with Graves’ disease. Frontiers in cellular and infection microbiology. 2021;11:663131.

Küçükemre Aydın B, Yıldız M, et al. Children with Hashimoto's thyroiditis have increased intestinal permeability: results of a pilot study. Journal of Clinical Research in Pediatric Endocrinology.2020.

El Asmar R, Panigrahi P, Bamford P, et al. Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure. Gastroenterology. 2002;123(5):1607-15.

Fasano A. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. F1000Research. 2020;9:F1000 Faculty Rev-69.

Cayres LCdF, de Salis LVV, Rodrigues GSP, et al. Detection of alterations in the gut microbiota and intestinal permeability in patients with Hashimoto thyroiditis. Frontiers in immunology. 2021;12:579140.

Halawa MR, Ahmed IZ, Eid YM, et al. Study of Leaky Gut syndrome and its Correlation to Hashimoto’s Thyroid Disease with Respect to Antibodies Titre. QJM: An International Journal of Medicine. 2024;117(Supplement_2):hcae175. 424.

Kiseleva E, Mikhailopulo K, Sviridov O, et al. The role of components of Bifidobacterium and Lactobacillus in pathogenesis and serologic diagnosis of autoimmune thyroid diseases. Beneficial microbes. 2011;2(2):139-54.

Su X, Yin X, Liu Y, Yan X, et al. Gut dysbiosis contributes to the imbalance of Treg and Th17 cells in Graves’ disease patients by propionic acid. The Journal of Clinical Endocrinology & Metabolism. 2020;105(11):3526-47.

Chen J, Wang W, Guo Z, et al. Associations between gut microbiota and thyroidal function status in Chinese patients with Graves’ disease. Journal of Endocrinological Investigation. 2021:1-14.

Sawicka-Gutaj N, Gruszczyński D, Zawalna N, et al. Microbiota alterations in patients with autoimmune thyroid diseases: a systematic review. International Journal of Molecular Sciences. 2022;23(21):13450.

Klasson CL, Sadhir S, Pontzer H. Daily physical activity is negatively associated with thyroid hormone levels, inflammation, and immune system markers among men and women in the NHANES dataset. PLoS One. 2022;17(7):e0270221.

Fang L, Ning J. Recent advances in gut microbiota and thyroid disease: pathogenesis and therapeutics in autoimmune, neoplastic, and nodular conditions. Frontiers in Cellular and Infection Microbiology. 2024;14:1465928.

Zhang S, Zhao X, Wang X, et al. Gut microecology may be involved in the pathogenesis of hashimoto thyroiditis by reducing production of hydrogen sulfide. The Journal of Clinical Endocrinology & Metabolism. 2024;109(3):792-801.