Melatonin Hormunu İle Fiziksel Aktivite Düzeyi Arasındaki İlişki
Özet
Referanslar
Jayedi A, Soltani S, Emadi A, Zargar M, Najafi A. Aerobic Exercise and Weight Loss in Adults: A Systematic Review and Dose-Response Meta-Analysis. JAMA Netw Open. 2024;7(12):e2452185. doi:10.1001/jamanetworkopen.2024.52185
Oja, P., Memon, A.R., Titze, S. et al. Health Benefits of Different Sports: a Systematic Review and Meta-Analysis of Longitudinal and Intervention Studies Including 2.6 Million Adult Participants. Sports Med - Open 10, 46 (2024). https://doi.org/10.1186/s40798-024-00692-x
Li, J., Zang, L., Hao, S., & Wang, H. (2025). Comparative efficacy of different exercise types on body composition in university students: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Physiology, 16, 1537937.Janssen I, Leblanc AG. Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. Int J Behav Nutr Phys Act. 2010 May 11;7:40. doi: 10.1186/1479-5868-7-40. PMID: 20459784; PMCID: PMC2885312.
Adan A, Archer SN, Hidalgo MP, Di Milia L, Natale V, Randler C (2012) Circadian typology: a comprehensive review. Chronobiol Int 29(9):1153–1175
Roenneberg T, Wirz-Justice A, Merrow M (2003) Life between clocks: daily temporal patterns of human chronotypes. J Biol Rhythms 18:80–90
Kim S, Duecker GL, Hasher L, Goldstein D (2002) Children’s time of day preference: age, gender and ethnic differences. Pers Individ Dif 33:1083–1090
Adan A, Natale V (2002) Gender differences in morningness–eveningness preference. Chronobiol Int 19:709–720
Atkinson G, Drust B, Reilly T, Waterhouse J (2003) The relevance of melatonin to sports medicine and science. Sports Med33:809–831
Arendt, J. (1995). Melatonin and the mammalian pineal gland. Journal of Endocrinology, 144(3), 401–408.
Liu, T. & Borjigin, J. (2005). N-acetyltransferase is a key regulator of pineal melatonin production in vertebrates. Journal of Pineal Research, 38(1), 1–8.
Reiter, R. J., Tan, D. X., Qi, W., Manchester, L. C., Karbownik, M., & Calvo, J. R. (2000). Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo. Neurosignals, 9(3-4), 160-171.
Carrillo-Vico, A., Guerrero, J. M., Lardone, P. J., & Reiter, R. J. (2005). A review of the multiple actions of melatonin on the immune system. Endocrine, 27(2), 189–200.
Hill, S. M., et al. (2015). Melatonin and breast cancer: cellular mechanisms, clinical studies and future perspectives. Endocrine-Related Cancer, 22(3), R183–R204.
Pandi-Perumal, S. R., et al. (2008). Melatonin and human cardiovascular disease. Cardiovascular Drugs and Therapy, 22(5), 375–390.
Forbes-Robertson S, Dudley E, Vadgama P, Cook C, Drawer S, Kilduff L (2012) Circadian disruption and remedial intervention. Sports Med 42(3):185–208
Zeman, M., et al. (2005). Melatonin and blood pressure regulation. Neuroendocrinology Letters, 26(5), 435–440.
Reiter, R. J., et al. (2003). Melatonin reduces oxidative/nitrosative stress in cardiomyocytes. Journal of Pineal Research, 34(4), 213–219.
Dominguez-Rodriguez, A., et al. (2010). Low levels of melatonin in patients with acute myocardial infarction. International Journal of Cardiology, 145(3), 545–547.
Paulis, L., & Simko, F. (2007). Melatonin as a potential antihypertensive treatment. Journal of Pineal Research, 42(4), 319–322.
Petrosillo, G., et al. (2009). Melatonin protects against heart ischemia/reperfusion injury by inhibiting mitochondrial permeability transition pore opening. The FASEB Journal, 23(3), 793–802.
Reppert, S. M., & Weaver, D. R. (2002). Coordination of circadian timing in mammals. Nature, 418(6901), 935–941.
Takahashi, J. S. (2017). Transcriptional architecture of the mammalian circadian clock. Nature Reviews Genetics, 18(3), 164–179.
Czeisler, C. A., et al. (1999). Stability, precision, and near-24-hour period of the human circadian pacemaker. Science, 284(5423), 2177–2181.
Zhu L, Zee PC. Circadian rhythm sleep disorders. Neurol Clin. 2012 Nov;30(4):1167-91. doi: 10.1016/j.ncl.2012.08.011. PMID: 23099133; PMCID: PMC3523094.
Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354.
Haus, E. L., & Smolensky, M. H. (2013). Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation. Sleep Medicine Reviews, 17(4), 273–284.
Juliana, N., Azmi, L., Effendy, N. M., Mohd Fahmi Teng, N. I., Abu, I. F., Abu Bakar, N. N., ... & Das, S. (2023). Effect of circadian rhythm disturbance on the human musculoskeletal system and the importance of nutritional strategies. Nutrients, 15(3), 734.
Brito LC, Marin TC, Azevêdo L, Rosa-Silva JM, Shea SA, Thosar SS. Chronobiology of Exercise: Evaluating the Best Time to Exercise for Greater Cardiovascular and Metabolic Benefits. Compr Physiol. 2022 Jun 29;12(3):3621-3639. doi: 10.1002/cphy.c210036. PMID: 35766829; PMCID: PMC10214902.
Buxton, O. M., et al. (1997). Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 273(3), R1027–R1033.
Van Reeth, O., et al. (1994). Exercise selectively increases nocturnal plasma melatonin concentrations in healthy men. Journal of Clinical Endocrinology & Metabolism, 78(3), 638–641.
Miyazaki, T., et al. (2001). Effects of physical exercise on the circadian rhythm of human core body temperature. Chronobiology International, 18(2), 343–356.
Reid, K. J., et al. (2010). Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia. Sleep Medicine, 11(9), 934–940.
Barattini P, Dolci C, Montaruli A, Roveda E, Carandente F (2001) Resynchronization of blood pressure circadian rhythm after westward trans-7-meridian flight with and without melatonin treatment. Aviat Sp Environ Med 72(3):221–224
Atkinson G, Edwards B, Reilly T, Waterhouse J (2007) Exercise as a synchroniser of human circadian rhythm: an update and discussion of the methodological problems. Eur J Appl Physiol 99:331–341
Meeking DR, Wallace JD, Cuneo RC, Forsling M, Russell-Jones DL (1999) Exercise-induced GH secretion is enhanced by the oral ingestion of melatonin in healthy adult male subjects. Eur J Endocrinol 141(1):22–26
Mazepa RC, Cuevas MJ, Collado PS, Gonzales-Gallego J (1999) Melatonin increases muscle and liver glycogen content in nonexercised and exercised rats. Life Sci 66:153–160
Johe PD, Østerud B (2005) The in vivo effect of melatonin on cellular activation processes in human blood during strenuous physical exercise. J Pineal Res 39:324–330
Miyazaki T, Hashimoto S, Masubuchi S, Honma S, Honma KI (2001) Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise. Am J Physiol Regul Integr Comp Physiol 281:R197–R205
Buxton OM, Frank S, L’Hermite-Baleriaux M, Leproult R, Turek FW, van Cauter E (2003) Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am J Physiol Regul Integr Comp Physiol 284:R714–R724
Al-Rawaf HA, Gabr SA, Iqbal A, Alghadir AH. Effects of High-Intensity Interval Training on Melatonin Function and Cellular Lymphocyte Apoptosis in Sedentary Middle-Aged Men. Medicina. 2023; 59(7):1201. https://doi.org/10.3390/medicina59071201
Vitale JA, Bonato M, Galasso L, La Torre A, Merati G, Montaruli A, Roveda E, Carandente F (2017) Sleep quality and high intensity interval training at two different times of day: a crossover study on the influence of the chronotype in male collegiate soccer players. Chronobiol Int 34(2):260–268
Montaruli A, Roveda E, Calogiuri G, La Torre A, Carandente F (2009) The sportsman readjustment after transcontinental flight: a study on marathon runners. J Sports Med Phys Fit 49(4):372–381
Leonardo-Mendonc¸a RC, Martinez-Nicolas A, de Teresa Galva´n C, Ocan˜a-Wilhelmi J, Rusanova I, Guerra-Herna´ndez E, Escames G, Acun˜a-Castroviejo D (2015) The benefits of four weeks of melatonin treatment on circadian patterns in resistance-trained athletes. Chronobiol Int 32(8):1125–1134
Atkinson G, Drust B, Reilly T, Waterhouse J (2003) The relevance of melatonin to sports medicine and science. Sports Med 33:809–831
Faria, V. S., Pejon, T. M. M., Gobatto, C. A., de Araujo, G. G., Cornachione, A. S., & Beck, W. R. (2021). Acute melatonin administration improves exercise tolerance and the metabolic recovery after exhaustive effort. Scientific reports, 11(1), 19228. https://doi.org/10.1038/s41598-021-97364-7
Veneroso, C., Tuñón, M. J., González-Gallego, J., & Collado, P. S. (2009). Melatonin reduces cardiac inflammatory injury induced by acute exercise. Journal of pineal research, 47(2), 184–191. https://doi.org/10.1111/j.1600-079X.2009.00699.x
Thrift AP, Xiao L, Patel SR, Tworoger SS, McTiernan A, Duggan C. Effects of physical activity on melatonin levels in previously sedentary men and women. Cancer Epidemiol Biomarkers Prev. 2014 Aug;23(8):1696-9. doi: 10.1158/1055-9965.EPI-14-0299. Epub 2014 May 23. PMID: 24859868; PMCID: PMC4119501.
Rigamonti, A. E., Rubino, F. M., Caroli, D., Bondesan, A., Mai, S., Cella, S. G., Centofanti, L., Paroni, R., & Sartorio, A. (2024). Effects of Melatonin on Exercise-Induced Oxidative Stress in Adults with Obesity Undergoing a Multidisciplinary Body Weight Reduction Program. Journal of clinical medicine, 13(17), 5216. https://doi.org/10.3390/jcm13175216
Bruno E, Roveda E, Vitale JA, Montaruli A, Berrino F, Villarini A, Venturelli E, Gargano G, Galasso L, Caumo A, Carandente F, Pasanisi P (2016) Effect of aerobic exercise intervention on markers of insulin resistance in breast cancer women. Eur J Cancer Care. doi:10.1111/ecc.12617 (Epub ahead of print)
Monteleone, P., Maj, M., Fusco, M., Orazzo, C., & Kemali, D. (1990). Physical exercise at night blunts the nocturnal increase of plasma melatonin levels in healthy humans. Life sciences, 47(22), 1989–1995. https://doi.org/10.1016/0024-3205(90)90432-q
Buxton, O. M., L'Hermite-Balériaux, M., Hirschfeld, U., & Cauter, E. (1997). Acute and delayed effects of exercise on human melatonin secretion. Journal of biological rhythms, 12(6), 568–574. https://doi.org/10.1177/074873049701200611
Siranart, N., Tokavanich, N., Keawkanha, P., Sowalertrat, W., Pajareya, P., Joensahakij, S., ... & Chokesuwattanaskul, R. (2024). Evening Exercise Does Not Affect Sleep Health: A Systematic Review and Meta-Analysis.
Yamanaka, Y., Hashimoto, S., Takasu, N. N., Tanahashi, Y., Nishide, S. Y., Honma, S., & Honma, K. (2015). Morning and evening physical exercise differentially regulate the autonomic nervous system during nocturnal sleep in humans. American journal of physiology. Regulatory, integrative and comparative physiology, 309(9), R1112–R1121. https://doi.org/10.1152/ajpregu.00127.2015
Carlson, L. A., Pobocik, K. M., Lawrence, M. A., Brazeau, D. A., & Koch, A. J. (2019). Influence of Exercise Time of Day on Salivary Melatonin Responses. International journal of sports physiology and performance, 14(3), 351–353. https://doi.org/10.1123/ijspp.2018-0073
Beck, W. R., Messias, L. H. D., Silva, F. C. D., Manchado-Gobatto, F. B., & Gobatto, C. A. (2018). Acute melatonin administration enhances aerobic tolerance: an analysis of biochemical and hematological parameters. Motriz: Revista de Educação Física, 24(02), e1018169.
Rahman MM, Kwon HS, Kim MJ, Go HK, Oak MH, Kim DH. Melatonin supplementation plus exercise behavior ameliorate insulin resistance, hypertension and fatigue in a rat model of type 2 diabetes mellitus. Biomed Pharmacother. 2017 Aug;92:606-614. doi: 10.1016/j.biopha.2017.05.035. Epub 2017 Jun 1. PMID: 28578257.
Cheikh M, Hammouda O, Gaamouri N, Driss T, Chamari K, Cheikh RB, Dogui M, Souissi N. Melatonin ingestion after exhaustive late-evening exercise improves sleep quality and quantity, and short-term performances in teenage athletes. Chronobiol Int. 2018 Sep;35(9):1281-1293. doi: 10.1080/07420528.2018.1474891. Epub 2018 May 30. PMID: 29846091.
Herxheimer, A., & Petrie, K. J. (2002). Melatonin for the prevention and treatment of jet lag. Cochrane Database of Systematic Reviews, (2).
Viswanathan AN, Schernhammer ES. Circulating melatonin and the risk of breast and endometrial cancer in women. Cancer Lett 2009;281:1–7.
Fraschini F, Cesarani A, Alpini D, Esposti D, Stankov BM (1999) Melatonin influences human balance. Biol Signals Recept 8:111–119
Atkinson G, Buckley P, Edwards B, Reilly T, Waterhouse J (2001) Are there hangover-effects on physical performance when melatonin is ingested by athletes before nocturnal sleep? Int J Sports Med 22:232–234
Arikawa AY, Thomas W, Patel SR, Kurzer MS. No effect of exercise on urinary 6-sulfatoxymelatonin and catecholamines in young women participating in a 16-week randomized controlled trial. Cancer Epidemiol Biomarkers Prev 2013;22:1634–6
Maldonado, M. D., Manfredi, M., Ribas-Serna, J., Garcia-Moreno, H., & Calvo, J. R. (2012). Melatonin administrated immediately before an intense exercise reverses oxidative stress, improves immunological defenses and lipid metabolism in football players. Physiology & behavior, 105(5), 1099–1103. https://doi.org/10.1016/j.physbeh.2011.12.015
Farjallah, M. A., Graja, A., Mahmoud, L. B., Ghattassi, K., Boudaya, M., Driss, T., Jamoussi, K., Sahnoun, Z., Souissi, N., & Hammouda, O. (2022). Effects of melatonin ingestion on physical performance and biochemical responses following exhaustive running exercise in soccer players. Biology of sport, 39(2), 473–479. https://doi.org/10.5114/biolsport.2022.106385
McTiernan A. (2008). Mechanisms linking physical activity with cancer. Nature reviews. Cancer, 8(3), 205–211. https://doi.org/10.1038/nrc2325
Escames, G., Ozturk, G., Baño-Otálora, B., Pozo, M. J., Madrid, J. A., Reiter, R. J., Serrano, E., Concepción, M., & Acuña-Castroviejo, D. (2012). Exercise and melatonin in humans: reciprocal benefits. Journal of pineal research, 52(1), 1–11. https://doi.org/10.1111/j.1600-079X.2011.00924.x
Arikawa, A. Y., Thomas, W., Patel, S. R., & Kurzer, M. S. (2013). No effect of exercise on urinary 6-sulfatoxymelatonin and catecholamines in young women participating in a 16-week randomized controlled trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 22(9), 1634–1636. https://doi.org/10.1158/1055-9965.EPI-13-0583
Referanslar
Jayedi A, Soltani S, Emadi A, Zargar M, Najafi A. Aerobic Exercise and Weight Loss in Adults: A Systematic Review and Dose-Response Meta-Analysis. JAMA Netw Open. 2024;7(12):e2452185. doi:10.1001/jamanetworkopen.2024.52185
Oja, P., Memon, A.R., Titze, S. et al. Health Benefits of Different Sports: a Systematic Review and Meta-Analysis of Longitudinal and Intervention Studies Including 2.6 Million Adult Participants. Sports Med - Open 10, 46 (2024). https://doi.org/10.1186/s40798-024-00692-x
Li, J., Zang, L., Hao, S., & Wang, H. (2025). Comparative efficacy of different exercise types on body composition in university students: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Physiology, 16, 1537937.Janssen I, Leblanc AG. Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. Int J Behav Nutr Phys Act. 2010 May 11;7:40. doi: 10.1186/1479-5868-7-40. PMID: 20459784; PMCID: PMC2885312.
Adan A, Archer SN, Hidalgo MP, Di Milia L, Natale V, Randler C (2012) Circadian typology: a comprehensive review. Chronobiol Int 29(9):1153–1175
Roenneberg T, Wirz-Justice A, Merrow M (2003) Life between clocks: daily temporal patterns of human chronotypes. J Biol Rhythms 18:80–90
Kim S, Duecker GL, Hasher L, Goldstein D (2002) Children’s time of day preference: age, gender and ethnic differences. Pers Individ Dif 33:1083–1090
Adan A, Natale V (2002) Gender differences in morningness–eveningness preference. Chronobiol Int 19:709–720
Atkinson G, Drust B, Reilly T, Waterhouse J (2003) The relevance of melatonin to sports medicine and science. Sports Med33:809–831
Arendt, J. (1995). Melatonin and the mammalian pineal gland. Journal of Endocrinology, 144(3), 401–408.
Liu, T. & Borjigin, J. (2005). N-acetyltransferase is a key regulator of pineal melatonin production in vertebrates. Journal of Pineal Research, 38(1), 1–8.
Reiter, R. J., Tan, D. X., Qi, W., Manchester, L. C., Karbownik, M., & Calvo, J. R. (2000). Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo. Neurosignals, 9(3-4), 160-171.
Carrillo-Vico, A., Guerrero, J. M., Lardone, P. J., & Reiter, R. J. (2005). A review of the multiple actions of melatonin on the immune system. Endocrine, 27(2), 189–200.
Hill, S. M., et al. (2015). Melatonin and breast cancer: cellular mechanisms, clinical studies and future perspectives. Endocrine-Related Cancer, 22(3), R183–R204.
Pandi-Perumal, S. R., et al. (2008). Melatonin and human cardiovascular disease. Cardiovascular Drugs and Therapy, 22(5), 375–390.
Forbes-Robertson S, Dudley E, Vadgama P, Cook C, Drawer S, Kilduff L (2012) Circadian disruption and remedial intervention. Sports Med 42(3):185–208
Zeman, M., et al. (2005). Melatonin and blood pressure regulation. Neuroendocrinology Letters, 26(5), 435–440.
Reiter, R. J., et al. (2003). Melatonin reduces oxidative/nitrosative stress in cardiomyocytes. Journal of Pineal Research, 34(4), 213–219.
Dominguez-Rodriguez, A., et al. (2010). Low levels of melatonin in patients with acute myocardial infarction. International Journal of Cardiology, 145(3), 545–547.
Paulis, L., & Simko, F. (2007). Melatonin as a potential antihypertensive treatment. Journal of Pineal Research, 42(4), 319–322.
Petrosillo, G., et al. (2009). Melatonin protects against heart ischemia/reperfusion injury by inhibiting mitochondrial permeability transition pore opening. The FASEB Journal, 23(3), 793–802.
Reppert, S. M., & Weaver, D. R. (2002). Coordination of circadian timing in mammals. Nature, 418(6901), 935–941.
Takahashi, J. S. (2017). Transcriptional architecture of the mammalian circadian clock. Nature Reviews Genetics, 18(3), 164–179.
Czeisler, C. A., et al. (1999). Stability, precision, and near-24-hour period of the human circadian pacemaker. Science, 284(5423), 2177–2181.
Zhu L, Zee PC. Circadian rhythm sleep disorders. Neurol Clin. 2012 Nov;30(4):1167-91. doi: 10.1016/j.ncl.2012.08.011. PMID: 23099133; PMCID: PMC3523094.
Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354.
Haus, E. L., & Smolensky, M. H. (2013). Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation. Sleep Medicine Reviews, 17(4), 273–284.
Juliana, N., Azmi, L., Effendy, N. M., Mohd Fahmi Teng, N. I., Abu, I. F., Abu Bakar, N. N., ... & Das, S. (2023). Effect of circadian rhythm disturbance on the human musculoskeletal system and the importance of nutritional strategies. Nutrients, 15(3), 734.
Brito LC, Marin TC, Azevêdo L, Rosa-Silva JM, Shea SA, Thosar SS. Chronobiology of Exercise: Evaluating the Best Time to Exercise for Greater Cardiovascular and Metabolic Benefits. Compr Physiol. 2022 Jun 29;12(3):3621-3639. doi: 10.1002/cphy.c210036. PMID: 35766829; PMCID: PMC10214902.
Buxton, O. M., et al. (1997). Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 273(3), R1027–R1033.
Van Reeth, O., et al. (1994). Exercise selectively increases nocturnal plasma melatonin concentrations in healthy men. Journal of Clinical Endocrinology & Metabolism, 78(3), 638–641.
Miyazaki, T., et al. (2001). Effects of physical exercise on the circadian rhythm of human core body temperature. Chronobiology International, 18(2), 343–356.
Reid, K. J., et al. (2010). Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia. Sleep Medicine, 11(9), 934–940.
Barattini P, Dolci C, Montaruli A, Roveda E, Carandente F (2001) Resynchronization of blood pressure circadian rhythm after westward trans-7-meridian flight with and without melatonin treatment. Aviat Sp Environ Med 72(3):221–224
Atkinson G, Edwards B, Reilly T, Waterhouse J (2007) Exercise as a synchroniser of human circadian rhythm: an update and discussion of the methodological problems. Eur J Appl Physiol 99:331–341
Meeking DR, Wallace JD, Cuneo RC, Forsling M, Russell-Jones DL (1999) Exercise-induced GH secretion is enhanced by the oral ingestion of melatonin in healthy adult male subjects. Eur J Endocrinol 141(1):22–26
Mazepa RC, Cuevas MJ, Collado PS, Gonzales-Gallego J (1999) Melatonin increases muscle and liver glycogen content in nonexercised and exercised rats. Life Sci 66:153–160
Johe PD, Østerud B (2005) The in vivo effect of melatonin on cellular activation processes in human blood during strenuous physical exercise. J Pineal Res 39:324–330
Miyazaki T, Hashimoto S, Masubuchi S, Honma S, Honma KI (2001) Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise. Am J Physiol Regul Integr Comp Physiol 281:R197–R205
Buxton OM, Frank S, L’Hermite-Baleriaux M, Leproult R, Turek FW, van Cauter E (2003) Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am J Physiol Regul Integr Comp Physiol 284:R714–R724
Al-Rawaf HA, Gabr SA, Iqbal A, Alghadir AH. Effects of High-Intensity Interval Training on Melatonin Function and Cellular Lymphocyte Apoptosis in Sedentary Middle-Aged Men. Medicina. 2023; 59(7):1201. https://doi.org/10.3390/medicina59071201
Vitale JA, Bonato M, Galasso L, La Torre A, Merati G, Montaruli A, Roveda E, Carandente F (2017) Sleep quality and high intensity interval training at two different times of day: a crossover study on the influence of the chronotype in male collegiate soccer players. Chronobiol Int 34(2):260–268
Montaruli A, Roveda E, Calogiuri G, La Torre A, Carandente F (2009) The sportsman readjustment after transcontinental flight: a study on marathon runners. J Sports Med Phys Fit 49(4):372–381
Leonardo-Mendonc¸a RC, Martinez-Nicolas A, de Teresa Galva´n C, Ocan˜a-Wilhelmi J, Rusanova I, Guerra-Herna´ndez E, Escames G, Acun˜a-Castroviejo D (2015) The benefits of four weeks of melatonin treatment on circadian patterns in resistance-trained athletes. Chronobiol Int 32(8):1125–1134
Atkinson G, Drust B, Reilly T, Waterhouse J (2003) The relevance of melatonin to sports medicine and science. Sports Med 33:809–831
Faria, V. S., Pejon, T. M. M., Gobatto, C. A., de Araujo, G. G., Cornachione, A. S., & Beck, W. R. (2021). Acute melatonin administration improves exercise tolerance and the metabolic recovery after exhaustive effort. Scientific reports, 11(1), 19228. https://doi.org/10.1038/s41598-021-97364-7
Veneroso, C., Tuñón, M. J., González-Gallego, J., & Collado, P. S. (2009). Melatonin reduces cardiac inflammatory injury induced by acute exercise. Journal of pineal research, 47(2), 184–191. https://doi.org/10.1111/j.1600-079X.2009.00699.x
Thrift AP, Xiao L, Patel SR, Tworoger SS, McTiernan A, Duggan C. Effects of physical activity on melatonin levels in previously sedentary men and women. Cancer Epidemiol Biomarkers Prev. 2014 Aug;23(8):1696-9. doi: 10.1158/1055-9965.EPI-14-0299. Epub 2014 May 23. PMID: 24859868; PMCID: PMC4119501.
Rigamonti, A. E., Rubino, F. M., Caroli, D., Bondesan, A., Mai, S., Cella, S. G., Centofanti, L., Paroni, R., & Sartorio, A. (2024). Effects of Melatonin on Exercise-Induced Oxidative Stress in Adults with Obesity Undergoing a Multidisciplinary Body Weight Reduction Program. Journal of clinical medicine, 13(17), 5216. https://doi.org/10.3390/jcm13175216
Bruno E, Roveda E, Vitale JA, Montaruli A, Berrino F, Villarini A, Venturelli E, Gargano G, Galasso L, Caumo A, Carandente F, Pasanisi P (2016) Effect of aerobic exercise intervention on markers of insulin resistance in breast cancer women. Eur J Cancer Care. doi:10.1111/ecc.12617 (Epub ahead of print)
Monteleone, P., Maj, M., Fusco, M., Orazzo, C., & Kemali, D. (1990). Physical exercise at night blunts the nocturnal increase of plasma melatonin levels in healthy humans. Life sciences, 47(22), 1989–1995. https://doi.org/10.1016/0024-3205(90)90432-q
Buxton, O. M., L'Hermite-Balériaux, M., Hirschfeld, U., & Cauter, E. (1997). Acute and delayed effects of exercise on human melatonin secretion. Journal of biological rhythms, 12(6), 568–574. https://doi.org/10.1177/074873049701200611
Siranart, N., Tokavanich, N., Keawkanha, P., Sowalertrat, W., Pajareya, P., Joensahakij, S., ... & Chokesuwattanaskul, R. (2024). Evening Exercise Does Not Affect Sleep Health: A Systematic Review and Meta-Analysis.
Yamanaka, Y., Hashimoto, S., Takasu, N. N., Tanahashi, Y., Nishide, S. Y., Honma, S., & Honma, K. (2015). Morning and evening physical exercise differentially regulate the autonomic nervous system during nocturnal sleep in humans. American journal of physiology. Regulatory, integrative and comparative physiology, 309(9), R1112–R1121. https://doi.org/10.1152/ajpregu.00127.2015
Carlson, L. A., Pobocik, K. M., Lawrence, M. A., Brazeau, D. A., & Koch, A. J. (2019). Influence of Exercise Time of Day on Salivary Melatonin Responses. International journal of sports physiology and performance, 14(3), 351–353. https://doi.org/10.1123/ijspp.2018-0073
Beck, W. R., Messias, L. H. D., Silva, F. C. D., Manchado-Gobatto, F. B., & Gobatto, C. A. (2018). Acute melatonin administration enhances aerobic tolerance: an analysis of biochemical and hematological parameters. Motriz: Revista de Educação Física, 24(02), e1018169.
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