Büyükbaş ve Küçükbaş Hayvanlarda Beslenme Hastalıkları

G. Wu, “Management of metabolic disorders (including metabolic diseases) in ruminant and nonruminant animals,” in Animal agriculture, Elsevier, 2020, pp. 471–491.

G. Wu, Principles of animal nutrition. crc Press, 2017.

T. H. Herdt, “Ruminant adaptation to negative energy balance: Influences on the etiology of ketosis and fatty liver,” Vet. Clin. North Am. Food Anim. Pract., vol. 16, no. 2, pp. 215–230, 2000.

E. N. Bergman, “Energy contributions of volatile fatty acids from the gastrointestinal tract in various species,” Physiol. Rev., vol. 70, no. 2, pp. 567–590, 1990.

T. C. Pithon‐Curi, M. P. De Melo, and R. Curi, “Glucose and glutamine utilization by rat lymphocytes, monocytes and neutrophils in culture: a comparative study,” Cell Biochem. Funct. Cell. Biochem. its Modul. by Act. agents or Dis., vol. 22, no. 5, pp. 321–326, 2004.

R. M. Bruckmaier and J. J. Gross, “Lactational challenges in transition dairy cows,” Anim. Prod. Sci., vol. 57, no. 7, pp. 1471–1481, 2017.

F. J. Mulligan and M. L. Doherty, “Production diseases of the transition cow,” Vet. J., vol. 176, no. 1, pp. 3–9, 2008.

K. L. Ingvartsen, “Feeding-and management-related diseases in the transition cow: Physiological adaptations around calving and strategies to reduce feeding-related diseases,” Anim. Feed Sci. Technol., vol. 126, no. 3–4, pp. 175–213, 2006.

K. L. Ingvartsen, R. J. Dewhurst, and N. C. Friggens, “On the relationship between lactational performance and health: is it yield or metabolic imbalance that cause production diseases in dairy cattle? A position paper,” Livest. Prod. Sci., vol. 83, no. 2–3, pp. 277–308, 2003.

M. E. Kehrli et al., “Energy and protein effects on the immune system,” in Ruminant physiology, Wageningen Academic, 2006, pp. 455–471.

V. Tufarelli, N. Puvača, D. Glamočić, G. Pugliese, and M. A. Colonna, “The most important metabolic diseases in dairy cattle during the transition period,” Animals, vol. 14, no. 5, p. 816, 2024.

Y. Lin, X. Sun, X. Hou, B. Qu, X. Gao, and Q. Li, “Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow,” BMC Vet. Res., vol. 12, pp. 1–11, 2016.

A. W. Bell and D. E. Bauman, “Adaptations of glucose metabolism during pregnancy and lactation,” J. Mammary Gland Biol. Neoplasia, vol. 2, pp. 265–278, 1997.

D. S. Kronfeld, “Major metabolic determinants of milk volume, mammary efficiency, and spontaneous ketosis in dairy cows,” J. Dairy Sci., vol. 65, no. 11, pp. 2204–2212, 1982.

M. Youssef and M. El-Ashker, “Significance of insulin resistance and oxidative stress in dairy cattle with subclinical ketosis during the transition period,” Trop. Anim. Health Prod., vol. 49, pp. 239–244, 2017.

M. C. Petersen and G. I. Shulman, “Mechanisms of insulin action and insulin resistance,” Physiol. Rev., 2018.

M. Zachut, H. Honig, S. Striem, Y. Zick, S. Boura-Halfon, and U. Moallem, “Periparturient dairy cows do not exhibit hepatic insulin resistance, yet adipose-specific insulin resistance occurs in cows prone to high weight loss,” J. Dairy Sci., vol. 96, no. 9, pp. 5656–5669, 2013.

N. Resources and E. National Academies of Sciences and Medicine, “Nutrient Requirements of Dairy Cattle,” 2021.

O. Balogh et al., “Interrelationship of growth hormone AluI polymorphism and hyperketonemia with plasma hormones and metabolites in the beginning of lactation in dairy cows,” Livest. Sci., vol. 123, no. 2–3, pp. 180–186, 2009.

J. H. Herbein, R. J. Aiello, L. I. Eckler, R. E. Pearson, and R. M. Akers, “Glucagon, insulin, growth hormone, and glucose concentrations in blood plasma of lactating dairy cows,” J. Dairy Sci., vol. 68, no. 2, pp. 320–325, 1985.

H. Martens, “The lipidosis of the liver of dairy cows: Part 1-Role of insulin and the Growth Hormone-IGF-1 axis,” Tierarztl. Prax. Ausg. G. Grosstiere. Nutztiere., vol. 51, no. 2, pp. 97–108, 2023.

V. H. Heemskerk, M. A. R. C. Daemen, and W. A. Buurman, “Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in immunity and inflammation,” Cytokine Growth Factor Rev., vol. 10, no. 1, pp. 5–14, 1999.

D. C. Wathes et al., “Associations between circulating IGF-1 concentrations, disease status and the leukocyte transcriptome in early lactation dairy cows,” Ruminants, vol. 1, no. 2, pp. 147–177, 2021.

A. I. Ateya, M. S. Hussein, H. M. Ghanem, R. M. Saleh, W. B. El‐Domany, and Y. Y. Elseady, “Expression profiles of immunity and reproductive genes during transition period in Holstein cattle,” Reprod. Domest. Anim., vol. 53, no. 2, pp. 352–358, 2018.

D. Kasagić, B. Radojičić, D. Gvozdić, M. Mirilović, and D. Matarugić, “Endocrine and metabolic profile in Holstein and red Holstein heifers during peripartal period,” Acta Vet., vol. 61, no. 5–6, pp. 555–565, 2011.

H. Gy, M. Kulcsár, and P. Rudas, “Clinical endocrinology of thyroid gland function in ruminants: A review of literature,” Vet. Med. Cz, vol. 47, pp. 191–202, 2002.

A. Hayirli, R. R. Grummer, E. V Nordheim, and P. M. Crump, “Animal and dietary factors affecting feed intake during the prefresh transition period in Holsteins,” J. Dairy Sci., vol. 85, no. 12, pp. 3430–3443, 2002.

R. J. Van Saun, “Metabolic profiling in ruminant diagnostics,” Vet. Clin. North Am. Food Anim. Pract., vol. 39, no. 1, pp. 49–71, 2023.

W. Xu, J. Vervoort, E. Saccenti, R. van Hoeij, B. Kemp, and A. van Knegsel, “Milk metabolomics data reveal the energy balance of individual dairy cows in early lactation,” Sci. Rep., vol. 8, no. 1, p. 15828, 2018.

A. Bannink et al., “Modelling the implications of feeding strategy on rumen fermentation and functioning of the rumen wall,” Anim. Feed Sci. Technol., vol. 143, no. 1–4, pp. 3–26, 2008.

T. Sakata, “Effects of short-chain fatty acids on the proliferation of gut epithelial cells,” in Physiological and clinical aspects of short-chain fatty acids, Cambridge University Press, 1995, pp. 289–305.

B. Etschmann, A. Suplie, and H. Martens, “Change of ruminal sodium transport in sheep during dietary adaptation,” Arch. Anim. Nutr., vol. 63, no. 1, pp. 26–38, 2009.

A. E. Von Ah Morano, G. P. Dorneles, A. Peres, and F. S. Lira, “The role of glucose homeostasis on immune function in response to exercise: The impact of low or higher energetic conditions,” J. Cell. Physiol., vol. 235, no. 4, pp. 3169–3188, 2020.

R. T. Watson, M. Kanzaki, and J. E. Pessin, “Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes,” Endocr. Rev., vol. 25, no. 2, pp. 177–204, 2004.

K. J. Na et al., “Reciprocal change in glucose metabolism of cancer and immune cells mediated by different glucose transporters predicts immunotherapy response,” Theranostics, vol. 10, no. 21, p. 9579, 2020.

S. K. Kvidera, E. A. Horst, E. J. Mayorga, M. V. Sanz-Fernández, M. Abuajamieh, and L. H. Baumgard, “Estimating glucose requirements of an activated immune system in growing pigs,” J. Anim. Sci., vol. 95, no. 11, pp. 5020–5029, 2017.

E. A. Horst et al., “Effects of maintaining eucalcemia following immunoactivation in lactating Holstein dairy cows,” J. Dairy Sci., vol. 103, no. 8, pp. 7472–7486, 2020.

M. Holzhauer and J. F. Valarcher, “Literature Review and Metanalysis of Fatty Liver Syndrome in Dairy Cows and Evaluation of Reference Values of Triacyl Glycerides in Liver and NEFA, BHB, Glucose and Insulin in Serum,” Curr. Trends Intern. Med, vol. 8, p. 213, 2024.

P. Melendez and P. Pinedo, “Update on Fatty Liver in Dairy Cattle with Major Emphasis on Epidemiological Patterns, Pathophysiology in Relationship to Abdominal Adiposity, and Early Diagnosis,” Dairy, vol. 5, no. 4, pp. 672–687, 2024.

R. M. Al Ibrahim, A. K. Kelly, L. O’Grady, V. P. Gath, C. McCarney, and F. J. Mulligan, “The effect of body condition score at calving and supplementation with Saccharomyces cerevisiae on milk production, metabolic status, and rumen fermentation of dairy cows in early lactation,” J. Dairy Sci., vol. 93, no. 11, pp. 5318–5328, 2010.

H. M. Dann, D. E. Morin, G. A. Bollero, M. R. Murphy, and J. K. Drackley, “Prepartum intake, postpartum induction of ketosis, and periparturient disorders affect the metabolic status of dairy cows,” J. Dairy Sci., vol. 88, no. 9, pp. 3249–3264, 2005.

S. Yonekura, “The role of endoplasmic reticulum stress in metabolic diseases and mammary epithelial cell homeostasis in dairy cows,” Anim. Sci. J., vol. 95, no. 1, p. e13935, 2024.

H. Hu et al., “An overview of the development of perinatal stress-induced fatty liver and therapeutic options in dairy cows,” Stress Biol., vol. 5, no. 1, p. 14, 2025.

J. K. Drackley and F. C. Cardoso, “Prepartum and postpartum nutritional management to optimize fertility in high-yielding dairy cows in confined TMR systems,” Animal, vol. 8, no. s1, pp. 5–14, 2014.

A. Mandal, The Focus on Core Genetic Factors That Regulate Hepatic Injury in Cattle Seems to Be Important for the Dairy Sector’s Long-Term Development. IntechOpen, 2022.

N. Katoh, “Relevance of apolipoproteins in the development of fatty liver and fatty liver-related peripartum diseases in dairy cows,” J. Vet. Med. Sci., vol. 64, no. 4, pp. 293–307, 2002.

R. Đoković, H. Šamanc, M. D. Petrović, Z. Ilić, and V. Kurćubić, “Relationship among blood metabolites and lipid content in the liver in transitional dairy cows,” Biotechnol. Anim. Husb., vol. 28, no. 4, pp. 705–714, 2012.

R. A. Nafikov, B. N. Ametaj, G. Bobe, J. W. Young, and D. C. Beitz, “Prevention of fatty liver in transition dairy cows by glucagon,” J Dairy Sci, vol. 85, no. Suppl 1, p. 21, 2002.

M. Fürll and B. Fürll, “Glucocorticoid (prednisolone) effects on various blood, urine and liver parameters in cows in the second post partum week,” Tierarztl. Prax. Ausg. G. Grosstiere. Nutztiere., vol. 26, no. 5, pp. 262–268, 1998.

A. Hayirli, S. J. Bertics, and R. R. Grummer, “Effects of slow-release insulin on production, liver triglyceride, and metabolic profiles of Holsteins in early lactation,” J. Dairy Sci., vol. 85, no. 9, pp. 2180–2191, 2002.

K. Wang, B. Xiong, and X. Zhao, “Could propionate formation be used to reduce enteric methane emission in ruminants?,” Sci. Total Environ., vol. 855, p. 158867, 2023.

A. E. Kulick, T. F. Gressley, J. A. A. Pires, and R. R. Grummer, “Effects of abomasal lipid infusion on liver triglyceride accumulation during fatty liver induction.,” J. Anim. Sci., vol. 84, 2006.

T. C. Skaar, R. R. Grummer, M. R. Dentine, and R. H. Stauffacher, “Seasonal effects of prepartum and postpartum fat and niacin feeding on lactation performance and lipid metabolism,” J. Dairy Sci., vol. 72, no. 8, pp. 2028–2038, 1989.

L. Wang, G. Zhang, Y. Li, and Y. Zhang, “Effects of high forage/concentrate diet on volatile fatty acid production and the microorganisms involved in VFA production in cow rumen,” Animals, vol. 10, no. 2, p. 223, 2020.

P. Holtenius and K. Holtenius, “New aspects of ketone bodies in energy metabolism of dairy cows: a review,” J. Vet. Med. Ser. A, vol. 43, no. 1‐10, pp. 579–587, 1996.

P. Guliński, “Ketone bodies–causes and effects of their increased presence in cows’ body fluids: A review,” Vet. world, vol. 14, no. 6, p. 1492, 2021.

O. M. Radostits, C. C. Gay, K. W. Hinchcliff, and P. D. Constable, Veterinary Medicine E-Book: Veterinary Medicine E-Book. Elsevier Health Sciences, 2006.

G. Zhang and B. N. Ametaj, “Ketosis an old story under a new approach,” Dairy, vol. 1, no. 1, p. 5, 2020.

X. U. Chuang, S. Tai-yu, Y. A. O. Yuan, Y. Hong-jiang, X. I. A. Cheng, and Z. Hong-you, “Blood clinicopathological differences between type I and II ketosis in dairy cows,” Indian J. Anim. Res., vol. 50, no. 5, pp. 753–758, 2016.

J. L. Gordon, S. J. LeBlanc, and T. F. Duffield, “Ketosis treatment in lactating dairy cattle,” Vet. Clin. Food Anim. Pract., vol. 29, no. 2, pp. 433–445, 2013.

F. Vicente et al., “Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages,” Sci. World J., vol. 2014, no. 1, p. 279614, 2014.

L. Andersson and K. Lundström, “Effect of feeding silage with high butyric acid content on ketone body formation and milk yield in postparturient dairy cows,” Zentralblatt für Veterinärmedizin R. A, vol. 32, no. 1‐10, pp. 15–23, 1985.

L. Kung Jr, “Understanding the biology of silage preservation to maximize quality and protect the environment,” in Proceedings, 2010 California Alfalfa & forage symposium and corn/cereal silage conference, 2010, pp. 1–2.

E. Madhesh, R. C. Sundararajan, V. Vijayanand, N. V Rajesh, M. Balagangatharathilagar, and R. B. Vishnurahav, “Therapeutic management of nervous form of ketosis in a dairy cow,” Pharm Innov, vol. 12, no. 10, pp. 1717–1719, 2023.

M. A. C. Lei and J. Simões, “Invited review: ketosis diagnosis and monitoring in high-producing dairy cows,” Dairy, vol. 2, no. 2, pp. 303–325, 2021.

V. K. Meena et al., “Prevalence and clinical findings of ketosis in postparturient cows in and around Bikaner.,” 2022.

B. S. Reddy, B. S. S. Reddy, Y. V. P. Reddy, and R. Vennkatasivakumar, “Nervous form of ketosis in cows and its treatment,” Int. J. Biol. Res, vol. 2, no. 2, pp. 143–144, 2014.

G. Cascone et al., “Subclinical ketosis in dairy herds: Impact of early diagnosis and treatment,” Front. Vet. Sci., vol. 9, p. 895468, 2022.

A. Hubner et al., “Characterization of metabolic profile, health, milk production, and reproductive outcomes of dairy cows diagnosed with concurrent hyperketonemia and hypoglycemia,” J. Dairy Sci., vol. 105, no. 11, pp. 9054–9069, 2022.

F. Enjalbert, M. C. Nicot, C. Bayourthe, and and R. Moncoulon, “Ketone bodies in milk and blood of dairy cows: Relationship between concentrations and utilization for detection of subclinical ketosis,” J. Dairy Sci., vol. 84, no. 3, pp. 583–589, 2001.

P. Gillund, O. Reksen, Y. T. Gröhn, and K. Karlberg, “Body condition related to ketosis and reproductive performance in Norwegian dairy cows,” J. Dairy Sci., vol. 84, no. 6, pp. 1390–1396, 2001.

J. R. Roche, J. K. Kay, N. C. Friggens, J. J. Loor, and D. P. Berry, “Assessing and managing body condition score for the prevention of metabolic disease in dairy cows,” Vet. Clin. Food Anim. Pract., vol. 29, no. 2, pp. 323–336, 2013.

M. Wukadinovich and H. A. Rossow, “Production Responses of Holstein Dairy Cows to a Sodium Propionate Supplement Fed Postpartum to Prevent Hyperketonemia,” Dairy, vol. 4, no. 4, pp. 527–540, 2023.

J. A. A. McArt, D. V Nydam, and G. R. Oetzel, “A field trial on the effect of propylene glycol on displaced abomasum, removal from herd, and reproduction in fresh cows diagnosed with subclinical ketosis,” J. Dairy Sci., vol. 95, no. 5, pp. 2505–2512, 2012.

X. Ji, N. Liu, Y. Wang, K. Ding, S. Huang, and C. Zhang, “Pregnancy toxemia in ewes: a review of molecular metabolic mechanisms and management strategies,” Metabolites, vol. 13, no. 2, p. 149, 2023.

N. R. C. (US). C. on N. R. of S. Ruminants, Nutrient requirements of small ruminants: sheep, goats, cervids, and new world camelids. 中国法制出版社, 2007.

A. Mongini and R. J. Van Saun, “Pregnancy toxemia in sheep and goats,” Vet. Clin. Food Anim. Pract., vol. 39, no. 2, pp. 275–291, 2023.

M. S. Allen, B. J. Bradford, and M. Oba, “Board-invited review: The hepatic oxidation theory of the control of feed intake and its application to ruminants,” J. Anim. Sci., vol. 87, no. 10, pp. 3317–3334, 2009.

J. E. Bayne, “Pregnancy Toxemia Therapeutic Options,” Vet. Clin. Food Anim. Pract., vol. 39, no. 2, pp. 293–305, 2023.

A. Kelay and A. Assefa, “Causes, Control and Prevention Methods of Pregnancy Toxemia in Ewe: A Review,” J. Life Sci. Biomed., vol. 8, no. 4, pp. 69–76, 2018.

A. M. van Vuuren, S. Calsamiglia, and P. Udén, “Rumen health: a 360 analysis,” 2012, Elsevier.

H. M. Golder et al., “Effects of grain, fructose, and histidine on ruminal pH and fermentation products during an induced subacute acidosis protocol,” J. Dairy Sci., vol. 95, no. 4, pp. 1971–1982, 2012.

T. G. Nagaraja and E. C. Titgemeyer, “Ruminal acidosis in beef cattle: the current microbiological and nutritional outlook,” J. Dairy Sci., vol. 90, pp. E17–E38, 2007.

G. R. Oetzel, “Clinical aspects of ruminal acidosis in dairy cattle,” in American Association of Bovine Practitioners Conference Proceedings, 2000, pp. 46–53.

F. N. Owens, D. S. Secrist, W. J. Hill, and D. R. Gill, “Acidosis in cattle: a review,” J. Anim. Sci., vol. 76, no. 1, pp. 275–286, 1998.

R. Stock, “Acidosis in cattle: an overview,” in American Association of Bovine Practitioners Conference Proceedings, 2000, pp. 30–37.

J. B. Russell, “Strategies that ruminal bacteria use to handle excess carbohydrate,” J. Anim. Sci., vol. 76, no. 7, pp. 1955–1963, 1998.

T. L. Huber, “Physiological effects of acidosis on feedlot cattle,” J. Anim. Sci., vol. 43, no. 4, pp. 902–909, 1976.

D. V Rayner, “Gastrointestinal satiety in animals other than man,” Proc. Nutr. Soc., vol. 51, no. 1, pp. 1–6, 1992.

P. Guilloteau, I. Le Huërou‐Luron, J. A. Chayvialle, R. Toullec, R. Zabielski, and J. W. Blum, “Gut regulatory peptides in young cattle and sheep,” J. Vet. Med. Ser. A, vol. 44, no. 1‐10, pp. 1–23, 1997.

A. L. Mordenti, E. Giaretta, L. Campidonico, P. Parazza, and A. Formigoni, “A review regarding the use of molasses in animal nutrition,” Animals, vol. 11, no. 1, p. 115, 2021.

E. Jaramillo-López, M. F. Itza-Ortiz, G. Peraza-Mercado, and J. M. Carrera-Chávez, “Ruminal acidosis: strategies for its control,” Austral J. Vet. Sci., vol. 49, no. 3, pp. 139–148, 2017.

J. B. Ewaschuk, J. M. Naylor, and G. A. Zello, “D-lactate in human and ruminant metabolism,” J. Nutr., vol. 135, no. 7, pp. 1619–1625, 2005.

J. Li, P. Ma, Z. Liu, and J. Xie, “L-and D-Lactate: unveiling their hidden functions in disease and health,” Cell Commun. Signal., vol. 23, no. 1, p. 134, 2025.

J. A. N. Mills et al., “A dynamic mechanistic model of lactic acid metabolism in the rumen,” J. Dairy Sci., vol. 97, no. 4, pp. 2398–2414, 2014.

B. E. Brent and E. E. Bartley, “Thiamin and niacin in the rumen,” J. Anim. Sci., vol. 59, no. 3, pp. 813–822, 1984.

I. J. Lean, H. M. Golder, and M. B. Hall, “Feeding, evaluating, and controlling rumen function,” Vet. Clin. Food Anim. Pract., vol. 30, no. 3, pp. 539–575, 2014.

X. Pan, X. Nan, L. Yang, L. Jiang, and B. Xiong, “Thiamine status, metabolism and application in dairy cows: a review,” Br. J. Nutr., vol. 120, no. 5, pp. 491–499, 2018.

Y. Xu and Z. Ding, “Physiological, biochemical and histopathological effects of fermentative acidosis in ruminant production: a minimal review,” Spanish J. Agric. Res., vol. 9, no. 2 SE-Animal production, pp. 414–422, May 2011, doi: 10.5424/sjar/20110902-177-10.

I. J. Lean, C. T. Westwood, H. M. Golder, and J. J. Vermunt, “Impact of nutrition on lameness and claw health in cattle,” Livest. Sci., vol. 156, no. 1, pp. 71–87, 2013, doi: https://doi.org/10.1016/j.livsci.2013.06.006.

M. S. Hindman, “Metabolic Diseases in Beef Cattle,” Vet. Clin. Food Anim. Pract., vol. 39, no. 2, pp. 337–353, Jul. 2023, doi: 10.1016/j.cvfa.2023.02.011.

M. E. Elmhadi, D. K. Ali, M. K. Khogali, and H. Wang, “Subacute ruminal acidosis in dairy herds: Microbiological and nutritional causes, consequences, and prevention strategies,” Anim. Nutr., vol. 10, pp. 148–155, 2022, doi: https://doi.org/10.1016/j.aninu.2021.12.008.

S. R. van Amstel and J. K. Shearer, “Review of Pododermatitis Circumscripta (Ulceration of the Sole) in Dairy Cows,” J. Vet. Intern. Med., vol. 20, no. 4, pp. 805–811, Jul. 2006, doi: https://doi.org/10.1111/j.1939-1676.2006.tb01789.x.

S. Lean, “Ruminal acidosis—Aetiopathogenesis, prevention and treatment,” Aust. Vet. Assoc, vol. 61, pp. 7–43, 2007.

B. Khorrami, P. Kheirandish, Q. Zebeli, and E. Castillo-Lopez, “Variations in fecal pH and fecal particle size due to changes in dietary starch: Their potential as an on-farm tool for assessing the risk of ruminal acidosis in dairy cattle,” Res. Vet. Sci., vol. 152, pp. 678–686, 2022.

E. Humer et al., “Invited review: Practical feeding management recommendations to mitigate the risk of subacute ruminal acidosis in dairy cattle,” J. Dairy Sci., vol. 101, no. 2, pp. 872–888, 2018.

E. Humer and Q. Zebeli, “Grains in ruminant feeding and potentials to enhance their nutritive and health value by chemical processing,” Anim. Feed Sci. Technol., vol. 226, pp. 133–151, 2017.

R. A. Patton, J. R. Patton, and S. E. Boucher, “Defining ruminal and total-tract starch degradation for adult dairy cattle using in vivo data,” J. Dairy Sci., vol. 95, no. 2, pp. 765–782, 2012.

P. K. Naik, “Bypass fat in dairy ration-a review,” Anim. Nutr. Feed Technol, vol. 13, pp. 147–163, 2013.

Q. Zebeli, D. Mansmann, H. Steingass, and B. N. Ametaj, “Balancing diets for physically effective fibre and ruminally degradable starch: A key to lower the risk of sub-acute rumen acidosis and improve productivity of dairy cattle,” Livest. Sci., vol. 127, no. 1, pp. 1–10, 2010.

K. Boddugari, R. J. Grant, R. Stock, and M. Lewis, “Maximal replacement of forage and concentrate with a new wet corn milling product for lactating dairy cows,” J. Dairy Sci., vol. 84, no. 4, pp. 873–884, 2001.

D. R. Mertens, “Creating a system for meeting the fiber requirements of dairy cows,” J. Dairy Sci., vol. 80, no. 7, pp. 1463–1481, 1997.

J. Heinrichs and P. Kononoff, “Evaluating particle size of forages and TMRs using the new Penn State Forage Particle Separator,” Pennsylvania State Univ. Coll. Agric. Sci. Coop. Ext. DAS, vol. 42, pp. 1–15, 2002.

T. J. DeVries and M. A. G. Von Keyserlingk, “Time of feed delivery affects the feeding and lying patterns of dairy cows,” J. Dairy Sci., vol. 88, no. 2, pp. 625–631, 2005.

J. L. Kleen, G. A. Hooijer, J. Rehage, and J. Noordhuizen, “Subacute ruminal acidosis (SARA): a review,” J. Vet. Med. Ser. A, vol. 50, no. 8, pp. 406–414, 2003.

J. C. Plaizier, D. O. Krause, G. N. Gozho, and B. W. McBride, “Subacute ruminal acidosis in dairy cows: the physiological causes, incidence and consequences,” Vet. J., vol. 176, no. 1, pp. 21–31, 2008.

G. S. Haritha, “Management of Periparturient Disorders,” Periparturient Dis. Cattle, pp. 409–420, 2024.

M. E. Hossain, “Sub-acute ruminal acidosis in dairy cows: Its causes, consequences and preventive measures,” Online J. Anim. Feed Res, vol. 10, no. 1, pp. 302–312, 2020.

C. Hearst et al., “Antibacterial activity of elder (Sambucus nigra L.) flower or berry against hospital pathogens,” J. Med. Plants Res., vol. 4, no. 17, pp. 1805–1809, 2010, doi: 10.5897/JMPR10.147.

E. F. Garrett, K. V Nordlund, W. J. Goodger, and G. R. Oetzel, “A cross-sectional field study investigating the effect of periparturient dietary management on ruminal pH in early lactation dairy cows,” J. Dairy Sci, vol. 80, no. Suppl 1, p. 169, 1997.

W. Z. Yang and K. A. Beauchemin, “Physically effective fiber: method of determination and effects on chewing, ruminal acidosis, and digestion by dairy cows,” J. Dairy Sci., vol. 89, no. 7, pp. 2618–2633, 2006.

R. A. Kohn and T. F. Dunlap, “Calculation of the buffering capacity of bicarbonate in the rumen and in vitro,” J. Anim. Sci., vol. 76, no. 6, pp. 1702–1709, 1998.

Q. Shu, H. S. Gill, R. A. Leng, and J. B. Rowe, “Immunization with a Streptococcus bovis vaccine administered by different routes against lactic acidosis in sheep,” Vet. J., vol. 159, no. 3, pp. 262–269, 2000.

J. Hernández, J. L. Benedito, A. Abuelo, and C. Castillo, “Ruminal acidosis in feedlot: from aetiology to prevention,” Sci. World J., vol. 2014, no. 1, p. 702572, 2014.

A. W. Turner and V. E. Hodgetts, “Buffer systems in the rumen of sheep. II. Buffering properties in relationship to composition.,” Aust. J. Agric. Res., vol. 6, no. 1, pp. 125–144, 1955.

S. K. Sanjay Kumar, S. S. Dagar, A. K. Puniya, and R. C. Upadhyay, “Changes in methane emission, rumen fermentation in response to diet and microbial interactions.,” 2013.

H. Lippke, J. L. Reaves, and N. L. Jacobson, “Rumen pressures associated with the scores of a bloat severity scale,” J. Anim. Sci., vol. 34, no. 1, pp. 171–175, 1972.

G. J. Vogel and C. Parrott, “Mortality survey in feedyards: the incidence of death from digestive, respiratory, and other causes in feedyards on the great plains.,” 1994.

R. C. Backus, Effect of elevated intrarumen pressure on rumen motility, eructation, and ventilation in cattle. University of California, Davis, 1991.

E. Kuusela, Grazing management for Nordic organic dairy farming. Joensuun yliopisto, 2004.

Y. Wang, W. Majak, and T. A. McAllister, “Frothy bloat in ruminants: cause, occurrence, and mitigation strategies,” Anim. Feed Sci. Technol., vol. 172, no. 1–2, pp. 103–114, 2012.

R. E. Howarth, “A review of bloat in cattle,” Can. Vet. J., vol. 16, no. 10, p. 281, 1975.

W. Majak, T. A. McAllister, D. McCartney, K. Stanford, and K. J. Cheng, “Bloat in cattle,” Alberta Agric. Rural Dev. Canada, 2003.

S. Sen, H. P. S. Makkar, and K. Becker, “Alfalfa saponins and their implication in animal nutrition,” J. Agric. Food Chem., vol. 46, no. 1, pp. 131–140, 1998.

E. Azad et al., “Characterization of the rumen and fecal microbiome in bloated and non-bloated cattle grazing alfalfa pastures and subjected to bloat prevention strategies,” Sci. Rep., vol. 9, no. 1, p. 4272, 2019.

G. H. Rajan, C. A. Morris, V. R. Carruthers, R. J. Wilkins, and T. T. Wheeler, “The relative abundance of a salivary protein, bSP30, is correlated with susceptibility to bloat in cattle herds selected for high or low bloat susceptibility,” Anim. Genet., vol. 27, no. 6, pp. 407–414, 1996.

T. Yirdachew and G. Mekonnen, “Review on bloat in cattle,” J. Vet. Med. Anim. Sci, vol. 5, no. 1, p. 1101, 2022.

B. R. Min, W. E. Pinchak, R. C. Anderson, J. D. Fulford, and R. Puchala, “Effects of condensed tannins supplementation level on weight gain and in vitro and in vivo bloat precursors in steers grazing winter wheat,” J. Anim. Sci., vol. 84, no. 9, pp. 2546–2554, 2006.

Y. A. Papadopoulos, E. Charmley, K. B. McRae, A. Farid, and M. A. Price, “Addition of white clover to orchardgrass pasture improves the performance of grazing lambs, but not herbage production,” Can. J. Anim. Sci., vol. 81, no. 4, pp. 517–523, 2001.

B. R. Min, W. E. Pinchak, D. Mathews, and J. D. Fulford, “In vitro rumen fermentation and in vivo bloat dynamics of steers grazing winter wheat to corn oil supplementation,” Anim. Feed Sci. Technol., vol. 133, no. 3–4, pp. 192–205, 2007.

M. Rohde, “The Gram-positive bacterial cell wall,” Microbiol. Spectr., vol. 7, no. 3, pp. 10–1128, 2019.

D. M. Perígolo, F. G. F. de Paula, M. G. Rosmaninho, P. P. de Souza, R. M. Lago, and M. H. Araujo, “Conversion of fatty acids into hydrocarbon fuels based on a sodium carboxylate intermediate,” Catal. Today, vol. 279, pp. 260–266, 2017.

R. C. Pasquali, M. P. Taurozzi, and C. Bregni, “Some considerations about the hydrophilic–lipophilic balance system,” Int. J. Pharm., vol. 356, no. 1–2, pp. 44–51, 2008.

R. A. Zinn, F. N. Owens, and R. A. Ware, “Flaking corn: processing mechanics, quality standards, and impacts on energy availability and performance of feedlot cattle,” J. Anim. Sci., vol. 80, no. 5, pp. 1145–1156, 2002.

T. Ran, A. M. Saleem, K. A. Beauchemin, G. B. Penner, and W. Yang, “Processing index of barley grain and dietary undigested neutral detergent fiber concentration affected chewing behavior, ruminal pH, and total tract nutrient digestibility of heifers fed a high-grain diet,” J. Anim. Sci., vol. 99, no. 1, p. skab011, 2021.

W. Z. Yang, K. A. Beauchemin, and L. M. Rode, “Effects of barley grain processing on extent of digestion and milk production of lactating cows,” J. Dairy Sci., vol. 83, no. 3, pp. 554–568, 2000.

D. W. Bevans, K. A. Beauchemin, K. S. Schwartzkopf-Genswein, J. J. McKinnon, and T. A. McAllister, “Effect of rapid or gradual grain adaptation on subacute acidosis and feed intake by feedlot cattle,” J. Anim. Sci., vol. 83, no. 5, pp. 1116–1132, 2005.

S. Mandawat, R. Singh, V. Galav, S. Kilaka, A. Choudhary, and A. Sewag, “Disorders of forestomach in large ruminants: A review,” Emergent Life Sci. Res., vol. 10, pp. 154–161, 2024.

D. C. Van Metre, G. Fecteau, J. K. House, and L. W. George, “Indigestion of late pregnancy in a cow,” J. Am. Vet. Med. Assoc., vol. 206, no. 5, pp. 625–628, 1995.

A. Bach, M. Baudon, G. Elcoso, J. Viejo, and A. Courillon, “Effects on rumen pH and feed intake of a dietary concentrate challenge in cows fed rations containing pH modulators with different neutralizing capacity,” J. Dairy Sci., vol. 106, no. 7, pp. 4580–4598, 2023.

P. D. Constable, K. W. Hinchcliff, S. H. Done, and W. Grünberg, Veterinary medicine: a textbook of the diseases of cattle, horses, sheep, pigs and goats. Elsevier Health Sciences, 2016.

J. Burgstaller, T. Wittek, and G. W. Smith, “Invited review: Abomasal emptying in calves and its potential influence on gastrointestinal disease,” J. Dairy Sci., vol. 100, no. 1, pp. 17–35, 2017.

R. J. Panciera, M. J. Boileau, and D. L. Step, “Tympany, acidosis, and mural emphysema of the stomach in calves: report of cases and experimental induction,” J. Vet. diagnostic Investig., vol. 19, no. 4, pp. 392–395, 2007.

T. S. Marshall, “Abomasal ulceration and tympany of calves,” Vet. Clin. North Am. Food Anim. Pract., vol. 25, no. 1, pp. 209–220, 2009.

B. L. Roeder, M. M. Chengappa, T. G. Nagaraja, T. B. Avery, and G. A. Kennedy, “Experimental induction of abdominal tympany, abomasitis, and abomasal ulceration by intraruminal inoculation of Clostridium perfringens type A in neonatal calves,” Am. J. Vet. Res., vol. 49, no. 2, pp. 201–207, 1988.

M. Chigerwe and J. V Hagey, “Refractometer assessment of colostral and serum IgG and milk total solids concentrations in dairy cattle,” BMC Vet. Res., vol. 10, pp. 1–6, 2014.

J. F. Mee, “Invited review: Bovine neonatal morbidity and mortality—Causes, risk factors, incidences, sequelae and prevention,” Reprod. Domest. Anim., vol. 58, pp. 15–22, 2023.

T. Wittek, P. D. Constable, and D. E. Morin, “Abomasal impaction in Holstein-Friesian cows: 80 cases (1980–2003),” J. Am. Vet. Med. Assoc., vol. 227, no. 2, pp. 287–291, 2005.

N. K. Singh, S. V Singh, and S. Jaiswal, “Abomasal impaction due to phytobezoariasis in buffalo.,” Vet. Pract., vol. 17, no. 2, 2016.

P. R. Ide and J. H. Henry, “Abomasal abnormalities in dairy cattle: a review of 90 clinical cases,” Can. Vet. J., vol. 5, no. 3, p. 46, 1964.

A. Simsek, S. Sekin, H. Icen, A. Kochan, O. Celik, and T. Yaman, “Abomasal impaction due to sand accumulation in two cows,” Large An. Rev, vol. 21, no. 3, pp. 125–127, 2015.

K. Yong et al., “Abomasum impaction in beef cattle due to high intake of distillers’ grain and treatment options in Southwest China.,” 2021.

D. Yasaswini et al., “Abomasal impaction in buffaloes: Risk factors, clinical indicators, necropsy findings, and histology studies,” Vet. Res. Commun., vol. 47, no. 1, pp. 179–189, 2023.

T. Wittek, K. Tischer, I. Körner, T. Sattler, P. D. Constable, and M. Fürll, “Effect of preoperative erythromycin or dexamethasone/vitamin C on postoperative abomasal emptying rate in dairy cows undergoing surgical correction of abomasal volvulus,” Vet. Surg., vol. 37, no. 6, pp. 537–544, 2008.

S. Van Winden and R. Kuiper, “Left displacement of the abomasum in dairy cattle: recent developments in epidemiological and etiological aspects,” Vet. Res., vol. 34, no. 1, pp. 47–56, 2003.

R. I. N. Gordo, “Contribuição para o estudo do deslocamento do abomaso numa exploração leiteira da região de Montemor-o-Velho,” 2009, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária.

K. Doll, M. Sickinger, and T. Seeger, “New aspects in the pathogenesis of abomasal displacement,” Vet. J., vol. 181, no. 2, pp. 90–96, 2009.

G. Dirksen, “Linksseitige Labmagenverlagerung bei Kalb und Jungrind.,” Tieraerztliche Umschau, vol. 36, 1981.

GEISHAUSER, REICHE, and SCHEMANN, “In vitro motility disorders associated with displaced abomasum in dairy cows,” Neurogastroenterol. Motil., vol. 10, no. 5, pp. 395–401, 1998.

L. A. G. Colturato, C. E. Thomaz, and C. B. da Silva, “Deslocamento de abomaso em bovinos leiteiros,” Pubvet, vol. 15, p. 162, 2020.

V. Wolf, H. Hamann, H. Scholz, and O. Distl, “Einflüsse auf das auftreten von labmagenverlagerungen bei deutschen Holstein kühen,” Dtsch Tierärztl Wschr, vol. 108, pp. 403–408, 2001.

R. Kuiper, “Abomasal diseases,” Bov. Pract., pp. 111–117, 1991.

E. de M. Panelli, “Deslocamento do abomaso à esquerda em bovinos leiteiros: da etiologia ao diagnóstico,” 2014.

N. R. Zwald, K. A. Weigel, Y. M. Chang, R. D. Welper, and J. S. Clay, “Genetic selection for health traits using producer-recorded data. I. Incidence rates, heritability estimates, and sire breeding values,” J. Dairy Sci., vol. 87, no. 12, pp. 4287–4294, 2004.

L. E. Hernández-Castellano, L. L. Hernandez, and R. M. Bruckmaier, “Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows,” Animal, vol. 14, no. 2, pp. 330–338, 2020.

G. R. Oetzel, “An update on hypocalcemia on dairy farms,” in Proceedings of the Four-State Dairy Nutrition and Management Conference, 2012, pp. 80–85.

H. A. Seifi, M. Mohri, A. Ehsani, E. Hosseini, and M. Chamsaz, “Interpretation of bovine serum total calcium: effects of adjustment for albumin and total protein,” Comp. Clin. Path., vol. 14, pp. 155–159, 2005.

J. R. Roche, “The incidence and control of hypocalcaemia in pasture-based systems.,” Acta Vet. Scand. Suppl., vol. 97, pp. 141–144, 2003.

T. A. Reinhardt, J. D. Lippolis, B. J. McCluskey, J. P. Goff, and R. L. Horst, “Prevalence of subclinical hypocalcemia in dairy herds,” Vet. J., vol. 188, no. 1, pp. 122–124, 2011.

T. A. Reinhardt, R. L. Horst, and J. P. Goff, “Calcium, phosphorus, and magnesium homeostasis in ruminants,” Vet. Clin. North Am. Food Anim. Pract., vol. 4, no. 2, pp. 331–350, 1988.

R. L. Horst, J. P. Goff, and T. A. Reinhardt, “Calcium and vitamin D metabolism during lactation,” J. Mammary Gland Biol. Neoplasia, vol. 2, pp. 253–263, 1997.

J. C. Fleet, “Vitamin D-mediated regulation of intestinal calcium absorption,” Nutrients, vol. 14, no. 16, p. 3351, 2022.

P. J. DeGaris and I. J. Lean, “Milk fever in dairy cows: A review of pathophysiology and control principles,” Vet. J., vol. 176, no. 1, pp. 58–69, 2008.

C. Eckermann-Ross, “Hormonal regulation and calcium metabolism in the rabbit,” Vet. Clin. North Am. Exot. Anim. Pract., vol. 11, no. 1, pp. 139–152, 2008.

S. Liu and L. D. Quarles, “How fibroblast growth factor 23 works,” J. Am. Soc. Nephrol., vol. 18, no. 6, pp. 1637–1647, 2007.

J. E. Blau and M. T. Collins, “The PTH-vitamin d-FGF23 axis,” Rev. Endocr. Metab. Disord., vol. 16, pp. 165–174, 2015.

D. D. Bikle, “Vitamin D: production, metabolism and mechanisms of action,” 2015.

J. P. Goff, T. A. Reinhardt, and R. L. Horst, “Enzymes and factors controlling vitamin D metabolism and action in normal and milk fever cows,” J. Dairy Sci., vol. 74, no. 11, pp. 4022–4032, 1991.

D. A. Norman et al., “Jejunal and ileal adaptation to alterations in dietary calcium: changes in calcium and magnesium absorption and pathogenetic role of parathyroid hormone and 1, 25-dihydroxyvitamin D.,” J. Clin. Invest., vol. 67, no. 6, pp. 1599–1603, 1981.

N. Tageldin and A. Martin, “Thyroid, parathyroid hormones and calcium homeostasis,” Anaesth. Intensive Care Med., vol. 21, no. 11, pp. 599–603, 2020.

M. Engel, “Untersuchungen zum Einfluss unterschiedlicher Anionenergänzungen auf die Pansenfermentation, die Spurenelementkonzentration im Serum, die Wasseraufnahme sowie das Harnvolumen bei fistulierten Kühen,” 2006.

R. L. Horst, J. P. Goff, and T. A. Reinhardt, “Advancing age results in reduction of intestinal and bone 1, 25-dihydroxyvitamin D receptor,” Endocrinology, vol. 126, no. 2, pp. 1053–1057, 1990.

C. Martins, M. A. Arcari, K. C. Welter, J. L. Gonçalves, and M. V. dos Santos, “Effect of dietary cation–anion difference on ruminal metabolism, total apparent digestibility, blood and renal acid–base regulation in lactating dairy cows,” animal, vol. 10, no. 1, pp. 64–74, 2016.

J. P. Goff, “Invited review: Mineral absorption mechanisms, mineral interactions that affect acid–base and antioxidant status, and diet considerations to improve mineral status,” J. Dairy Sci., vol. 101, no. 4, pp. 2763–2813, 2018.

J. P. Goff, “The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows,” Vet. J., vol. 176, no. 1, pp. 50–57, 2008.

J. Martín-Tereso and M. W. A. Verstegen, “A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle,” Nutr. Res. Rev., vol. 24, no. 2, pp. 228–243, 2011.

N. Martinez et al., “Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease,” J. Dairy Sci., vol. 95, no. 12, pp. 7158–7172, 2012.

C. F. Arechiga-Flores et al., “Hypocalcemia in the dairy cow. Review,” Rev. Mex. ciencias Pecu., vol. 13, no. 4, pp. 1025–1054, 2022.

J. J. Hodnik, J. Ježek, and J. Starič, “A review of vitamin D and its importance to the health of dairy cattle,” J. Dairy Res., vol. 87, no. S1, pp. 84–87, 2020.

E. Charbonneau, D. Pellerin, and G. R. Oetzel, “Impact of lowering dietary cation-anion difference in nonlactating dairy cows: A meta-analysis,” J. Dairy Sci., vol. 89, no. 2, pp. 537–548, 2006.

K. M. Glosson et al., “Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals,” JDS Commun., vol. 4, no. 6, pp. 449–453, 2023.

L. E. Hernández-Castellano, L. L. Hernandez, H. Sauerwein, and R. M. Bruckmaier, “Endocrine and metabolic changes in transition dairy cows are affected by prepartum infusions of a serotonin precursor,” J. Dairy Sci., vol. 100, no. 6, pp. 5050–5057, 2017.

L. Pinotti, M. Manoni, L. Ferrari, M. Tretola, R. Cazzola, and I. Givens, “The contribution of dietary magnesium in farm animals and human nutrition,” Nutrients, vol. 13, no. 2, p. 509, 2021.

H. Martens and M. Schweigel, “Pathophysiology of grass tetany and other hypomagnesemias: implications for clinical management,” Vet. Clin. North Am. Food Anim. Pract., vol. 16, no. 2, pp. 339–368, 2000.

D. C. da Silva, B. D. Fernandes, J. M. dos S. Lima, B. A. da Silva, G. P. Rodrigues, and E. J. O. de Souza, “Subclinical hypomagnesemia: Prevalence and causes in dairy cows in the semiarid region of the state of Paraíba, Brazil,” Rev. Bras. Saúde e Produção Anim., vol. 21, p. e2121132020, 2020.

J. P. Goff, “Macromineral physiology and application to the feeding of the dairy cow for prevention of milk fever and other periparturient mineral disorders,” Anim. Feed Sci. Technol., vol. 126, no. 3–4, pp. 237–257, 2006.

W. P. Weiss, “Macromineral digestion by lactating dairy cows: factors affecting digestibility of magnesium,” J. Dairy Sci., vol. 87, no. 7, pp. 2167–2171, 2004.

A. Zelal, “Hypomagnesemia tetany in cattle,” Adv. Dairy Res., vol. 5, no. 2, pp. 2–9, 2017.

R. M. McLean and N. X. Wang, “Potassium,” in Advances in food and nutrition research, vol. 96, Elsevier, 2021, pp. 89–121.

J. P. Goff and R. L. Horst, “Role of acid-base physiology on the pathogenesis of parturient hypocalcaemia (milk fever)-the DCAD theory in principal and practice,” 2003.

B. K. R. Dabbir and S. R. Rajavolu, “of Hypokalemia in Cows,” Latest Sci. Find. Rumin. Nutr. Pract. Implement. Res. Pract. Implement., p. 1, 2024.

S. U. Felix, C. N. Pauline, N. Ogunkunle, and A. Lushaikyaa, “Acute Hypokalemia,” Periparturient Dis. Cattle, pp. 213–226, 2024.

S. F. Peek, T. J. Divers, C. Guard, A. Rath, and W. C. Rebhun, “Hypokalemia, muscle weakness, and recumbency in dairy cattle,” Vet Ther, vol. 1, no. 4, pp. 235–244, 2000.

N. Sattler and G. Fecteau, “Hypokalemia syndrome in cattle,” Vet Clin North Am Food Anim Pr., vol. 30, no. 2, pp. 351–357, 2014.

S. Yogeshpriya and P. Selvara, “Mastery of potassium status and their consequences of hypokalemia in dairy cattle,” Shanlax Int. J. Vet. Sci., vol. 5, no. 3, pp. 1–5, 2018.

Z. Toprak Çınar and İ. Şen, “Determination of Potassium Levels in Dairy Cows in the Periparturient Period,” 2022.

J. P. Goff, “Macromineral disorders of the transition cow,” Vet. Clin. Food Anim. Pract., vol. 20, no. 3, pp. 471–494, 2004.

Y. Mehdi and I. Dufrasne, “Selenium in cattle: a review,” Molecules, vol. 21, no. 4, p. 545, 2016.

N. Suttle, Mineral nutrition of livestock. Cabi, 2010.

M. J. Kuhn, “The Potential Role of Vitamin E Analogs as Adjunctive Antioxidant Supplements for Transition Cows,” Dairy, vol. 4, no. 2, pp. 285–299, 2023.

B. Hosnedlova et al., “A summary of new findings on the biological effects of selenium in selected animal species—a critical review,” Int. J. Mol. Sci., vol. 18, no. 10, p. 2209, 2017.

J. Kessler, “Carences en selenium chez les ruminants: mesures prophylactiques.,” Rev. suisse d’agriculture, vol. 25, 1993.

D. R. Khanal and A. P. Knight, “Selenium: its role in livestock health and productivity,” J. Agric. Environ., vol. 11, pp. 101–106, 2010.

K. L. Urschel and E. C. McKenzie, “Nutritional influences on skeletal muscle and muscular disease,” Vet. Clin. Equine Pract., vol. 37, no. 1, pp. 139–175, 2021.

J. Asín et al., “Nutritional wasting disorders in sheep,” Animals, vol. 11, no. 2, p. 501, 2021.

C. J. Finno and E. C. McKenzie, “Vitamin E and Selenium-Related Manifestations of Muscle Disease,” Vet. Clin. Equine Pract., vol. 41, no. 1, pp. 77–93, 2025.

A. MacPherson, “Trace-mineral status of forages.,” 2000.

G. M. Hill and M. C. Shannon, “Copper and zinc nutritional issues for agricultural animal production,” Biol. Trace Elem. Res., vol. 188, pp. 148–159, 2019.

I. K. F. de Sousa et al., “Copper deficiency in sheep with high liver iron accumulation,” Vet. Med. Int., vol. 2012, no. 1, p. 207950, 2012.

D. T. Pal et al., “Effect of copper-and zinc-methionine supplementation on bioavailability, mineral status and tissue concentrations of copper and zinc in ewes,” J. Trace Elem. Med. Biol., vol. 24, no. 2, pp. 89–94, 2010.

L. Byrne and R. A. Murphy, “Relative bioavailability of trace minerals in production animal nutrition: A review,” Animals, vol. 12, no. 15, p. 1981, 2022.

M. A. Al-Bayati, D. A. Jamil, and H. A. Al-Aubaidy, “Cardiovascular effects of copper deficiency on activity of superoxide dismutase in diabetic nephropathy,” N. Am. J. Med. Sci., vol. 7, no. 2, p. 41, 2015.

M. Rondanelli et al., “Copper as dietary supplement for bone metabolism: a review,” Nutrients, vol. 13, no. 7, p. 2246, 2021.

O. K. S. Sudan, S. Arkaweet, and A. C. Trinidad, “Review on Copper’s Functional Roles, Copper X Mineral Interactions Affecting Absorption, Tissue Storage, and Cu Deficiency Swayback of Small Ruminants”.

A. A. Saka, O. S. Sowande, A. O. Yusuf, and F. O. Ogunleke, “Importance of dietary copper supplementation in ruminant production: A review,” Niger. J. Anim. Prod., vol. 49, no. 2, pp. 235–245, 2022.

A. O. Adogwa, T. Alleyne, and A. Mohammed, “Degenerative changes in the cerebral cortex in swayback disease lambs,” Alzheimer’s Dis. Rev., vol. 4, pp. 19–22, 1999.

M. Borobia et al., “Copper poisoning, a deadly hazard for sheep,” Animals, vol. 12, no. 18, p. 2388, 2022.

G. Wu, “Management of metabolic disorders (including metabolic diseases) in ruminant and nonruminant animals,” in Animal agriculture, Elsevier, 2020, pp. 471–491.

G. Wu, Principles of animal nutrition. crc Press, 2017.

T. H. Herdt, “Ruminant adaptation to negative energy balance: Influences on the etiology of ketosis and fatty liver,” Vet. Clin. North Am. Food Anim. Pract., vol. 16, no. 2, pp. 215–230, 2000.

E. N. Bergman, “Energy contributions of volatile fatty acids from the gastrointestinal tract in various species,” Physiol. Rev., vol. 70, no. 2, pp. 567–590, 1990.

T. C. Pithon‐Curi, M. P. De Melo, and R. Curi, “Glucose and glutamine utilization by rat lymphocytes, monocytes and neutrophils in culture: a comparative study,” Cell Biochem. Funct. Cell. Biochem. its Modul. by Act. agents or Dis., vol. 22, no. 5, pp. 321–326, 2004.

R. M. Bruckmaier and J. J. Gross, “Lactational challenges in transition dairy cows,” Anim. Prod. Sci., vol. 57, no. 7, pp. 1471–1481, 2017.

F. J. Mulligan and M. L. Doherty, “Production diseases of the transition cow,” Vet. J., vol. 176, no. 1, pp. 3–9, 2008.

K. L. Ingvartsen, “Feeding-and management-related diseases in the transition cow: Physiological adaptations around calving and strategies to reduce feeding-related diseases,” Anim. Feed Sci. Technol., vol. 126, no. 3–4, pp. 175–213, 2006.

K. L. Ingvartsen, R. J. Dewhurst, and N. C. Friggens, “On the relationship between lactational performance and health: is it yield or metabolic imbalance that cause production diseases in dairy cattle? A position paper,” Livest. Prod. Sci., vol. 83, no. 2–3, pp. 277–308, 2003.

M. E. Kehrli et al., “Energy and protein effects on the immune system,” in Ruminant physiology, Wageningen Academic, 2006, pp. 455–471.

V. Tufarelli, N. Puvača, D. Glamočić, G. Pugliese, and M. A. Colonna, “The most important metabolic diseases in dairy cattle during the transition period,” Animals, vol. 14, no. 5, p. 816, 2024.

Y. Lin, X. Sun, X. Hou, B. Qu, X. Gao, and Q. Li, “Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow,” BMC Vet. Res., vol. 12, pp. 1–11, 2016.

A. W. Bell and D. E. Bauman, “Adaptations of glucose metabolism during pregnancy and lactation,” J. Mammary Gland Biol. Neoplasia, vol. 2, pp. 265–278, 1997.

D. S. Kronfeld, “Major metabolic determinants of milk volume, mammary efficiency, and spontaneous ketosis in dairy cows,” J. Dairy Sci., vol. 65, no. 11, pp. 2204–2212, 1982.

M. Youssef and M. El-Ashker, “Significance of insulin resistance and oxidative stress in dairy cattle with subclinical ketosis during the transition period,” Trop. Anim. Health Prod., vol. 49, pp. 239–244, 2017.

M. C. Petersen and G. I. Shulman, “Mechanisms of insulin action and insulin resistance,” Physiol. Rev., 2018.

M. Zachut, H. Honig, S. Striem, Y. Zick, S. Boura-Halfon, and U. Moallem, “Periparturient dairy cows do not exhibit hepatic insulin resistance, yet adipose-specific insulin resistance occurs in cows prone to high weight loss,” J. Dairy Sci., vol. 96, no. 9, pp. 5656–5669, 2013.

N. Resources and E. National Academies of Sciences and Medicine, “Nutrient Requirements of Dairy Cattle,” 2021.

O. Balogh et al., “Interrelationship of growth hormone AluI polymorphism and hyperketonemia with plasma hormones and metabolites in the beginning of lactation in dairy cows,” Livest. Sci., vol. 123, no. 2–3, pp. 180–186, 2009.

J. H. Herbein, R. J. Aiello, L. I. Eckler, R. E. Pearson, and R. M. Akers, “Glucagon, insulin, growth hormone, and glucose concentrations in blood plasma of lactating dairy cows,” J. Dairy Sci., vol. 68, no. 2, pp. 320–325, 1985.

H. Martens, “The lipidosis of the liver of dairy cows: Part 1-Role of insulin and the Growth Hormone-IGF-1 axis,” Tierarztl. Prax. Ausg. G. Grosstiere. Nutztiere., vol. 51, no. 2, pp. 97–108, 2023.

V. H. Heemskerk, M. A. R. C. Daemen, and W. A. Buurman, “Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in immunity and inflammation,” Cytokine Growth Factor Rev., vol. 10, no. 1, pp. 5–14, 1999.

D. C. Wathes et al., “Associations between circulating IGF-1 concentrations, disease status and the leukocyte transcriptome in early lactation dairy cows,” Ruminants, vol. 1, no. 2, pp. 147–177, 2021.

A. I. Ateya, M. S. Hussein, H. M. Ghanem, R. M. Saleh, W. B. El‐Domany, and Y. Y. Elseady, “Expression profiles of immunity and reproductive genes during transition period in Holstein cattle,” Reprod. Domest. Anim., vol. 53, no. 2, pp. 352–358, 2018.

D. Kasagić, B. Radojičić, D. Gvozdić, M. Mirilović, and D. Matarugić, “Endocrine and metabolic profile in Holstein and red Holstein heifers during peripartal period,” Acta Vet., vol. 61, no. 5–6, pp. 555–565, 2011.

H. Gy, M. Kulcsár, and P. Rudas, “Clinical endocrinology of thyroid gland function in ruminants: A review of literature,” Vet. Med. Cz, vol. 47, pp. 191–202, 2002.

A. Hayirli, R. R. Grummer, E. V Nordheim, and P. M. Crump, “Animal and dietary factors affecting feed intake during the prefresh transition period in Holsteins,” J. Dairy Sci., vol. 85, no. 12, pp. 3430–3443, 2002.

R. J. Van Saun, “Metabolic profiling in ruminant diagnostics,” Vet. Clin. North Am. Food Anim. Pract., vol. 39, no. 1, pp. 49–71, 2023.

W. Xu, J. Vervoort, E. Saccenti, R. van Hoeij, B. Kemp, and A. van Knegsel, “Milk metabolomics data reveal the energy balance of individual dairy cows in early lactation,” Sci. Rep., vol. 8, no. 1, p. 15828, 2018.

A. Bannink et al., “Modelling the implications of feeding strategy on rumen fermentation and functioning of the rumen wall,” Anim. Feed Sci. Technol., vol. 143, no. 1–4, pp. 3–26, 2008.

T. Sakata, “Effects of short-chain fatty acids on the proliferation of gut epithelial cells,” in Physiological and clinical aspects of short-chain fatty acids, Cambridge University Press, 1995, pp. 289–305.

B. Etschmann, A. Suplie, and H. Martens, “Change of ruminal sodium transport in sheep during dietary adaptation,” Arch. Anim. Nutr., vol. 63, no. 1, pp. 26–38, 2009.

A. E. Von Ah Morano, G. P. Dorneles, A. Peres, and F. S. Lira, “The role of glucose homeostasis on immune function in response to exercise: The impact of low or higher energetic conditions,” J. Cell. Physiol., vol. 235, no. 4, pp. 3169–3188, 2020.

R. T. Watson, M. Kanzaki, and J. E. Pessin, “Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes,” Endocr. Rev., vol. 25, no. 2, pp. 177–204, 2004.

K. J. Na et al., “Reciprocal change in glucose metabolism of cancer and immune cells mediated by different glucose transporters predicts immunotherapy response,” Theranostics, vol. 10, no. 21, p. 9579, 2020.

S. K. Kvidera, E. A. Horst, E. J. Mayorga, M. V. Sanz-Fernández, M. Abuajamieh, and L. H. Baumgard, “Estimating glucose requirements of an activated immune system in growing pigs,” J. Anim. Sci., vol. 95, no. 11, pp. 5020–5029, 2017.

E. A. Horst et al., “Effects of maintaining eucalcemia following immunoactivation in lactating Holstein dairy cows,” J. Dairy Sci., vol. 103, no. 8, pp. 7472–7486, 2020.

M. Holzhauer and J. F. Valarcher, “Literature Review and Metanalysis of Fatty Liver Syndrome in Dairy Cows and Evaluation of Reference Values of Triacyl Glycerides in Liver and NEFA, BHB, Glucose and Insulin in Serum,” Curr. Trends Intern. Med, vol. 8, p. 213, 2024.

P. Melendez and P. Pinedo, “Update on Fatty Liver in Dairy Cattle with Major Emphasis on Epidemiological Patterns, Pathophysiology in Relationship to Abdominal Adiposity, and Early Diagnosis,” Dairy, vol. 5, no. 4, pp. 672–687, 2024.

R. M. Al Ibrahim, A. K. Kelly, L. O’Grady, V. P. Gath, C. McCarney, and F. J. Mulligan, “The effect of body condition score at calving and supplementation with Saccharomyces cerevisiae on milk production, metabolic status, and rumen fermentation of dairy cows in early lactation,” J. Dairy Sci., vol. 93, no. 11, pp. 5318–5328, 2010.

H. M. Dann, D. E. Morin, G. A. Bollero, M. R. Murphy, and J. K. Drackley, “Prepartum intake, postpartum induction of ketosis, and periparturient disorders affect the metabolic status of dairy cows,” J. Dairy Sci., vol. 88, no. 9, pp. 3249–3264, 2005.

S. Yonekura, “The role of endoplasmic reticulum stress in metabolic diseases and mammary epithelial cell homeostasis in dairy cows,” Anim. Sci. J., vol. 95, no. 1, p. e13935, 2024.

H. Hu et al., “An overview of the development of perinatal stress-induced fatty liver and therapeutic options in dairy cows,” Stress Biol., vol. 5, no. 1, p. 14, 2025.

J. K. Drackley and F. C. Cardoso, “Prepartum and postpartum nutritional management to optimize fertility in high-yielding dairy cows in confined TMR systems,” Animal, vol. 8, no. s1, pp. 5–14, 2014.

A. Mandal, The Focus on Core Genetic Factors That Regulate Hepatic Injury in Cattle Seems to Be Important for the Dairy Sector’s Long-Term Development. IntechOpen, 2022.

N. Katoh, “Relevance of apolipoproteins in the development of fatty liver and fatty liver-related peripartum diseases in dairy cows,” J. Vet. Med. Sci., vol. 64, no. 4, pp. 293–307, 2002.

R. Đoković, H. Šamanc, M. D. Petrović, Z. Ilić, and V. Kurćubić, “Relationship among blood metabolites and lipid content in the liver in transitional dairy cows,” Biotechnol. Anim. Husb., vol. 28, no. 4, pp. 705–714, 2012.

R. A. Nafikov, B. N. Ametaj, G. Bobe, J. W. Young, and D. C. Beitz, “Prevention of fatty liver in transition dairy cows by glucagon,” J Dairy Sci, vol. 85, no. Suppl 1, p. 21, 2002.

M. Fürll and B. Fürll, “Glucocorticoid (prednisolone) effects on various blood, urine and liver parameters in cows in the second post partum week,” Tierarztl. Prax. Ausg. G. Grosstiere. Nutztiere., vol. 26, no. 5, pp. 262–268, 1998.

A. Hayirli, S. J. Bertics, and R. R. Grummer, “Effects of slow-release insulin on production, liver triglyceride, and metabolic profiles of Holsteins in early lactation,” J. Dairy Sci., vol. 85, no. 9, pp. 2180–2191, 2002.

K. Wang, B. Xiong, and X. Zhao, “Could propionate formation be used to reduce enteric methane emission in ruminants?,” Sci. Total Environ., vol. 855, p. 158867, 2023.

A. E. Kulick, T. F. Gressley, J. A. A. Pires, and R. R. Grummer, “Effects of abomasal lipid infusion on liver triglyceride accumulation during fatty liver induction.,” J. Anim. Sci., vol. 84, 2006.

T. C. Skaar, R. R. Grummer, M. R. Dentine, and R. H. Stauffacher, “Seasonal effects of prepartum and postpartum fat and niacin feeding on lactation performance and lipid metabolism,” J. Dairy Sci., vol. 72, no. 8, pp. 2028–2038, 1989.

L. Wang, G. Zhang, Y. Li, and Y. Zhang, “Effects of high forage/concentrate diet on volatile fatty acid production and the microorganisms involved in VFA production in cow rumen,” Animals, vol. 10, no. 2, p. 223, 2020.

P. Holtenius and K. Holtenius, “New aspects of ketone bodies in energy metabolism of dairy cows: a review,” J. Vet. Med. Ser. A, vol. 43, no. 1‐10, pp. 579–587, 1996.

P. Guliński, “Ketone bodies–causes and effects of their increased presence in cows’ body fluids: A review,” Vet. world, vol. 14, no. 6, p. 1492, 2021.

O. M. Radostits, C. C. Gay, K. W. Hinchcliff, and P. D. Constable, Veterinary Medicine E-Book: Veterinary Medicine E-Book. Elsevier Health Sciences, 2006.

G. Zhang and B. N. Ametaj, “Ketosis an old story under a new approach,” Dairy, vol. 1, no. 1, p. 5, 2020.

X. U. Chuang, S. Tai-yu, Y. A. O. Yuan, Y. Hong-jiang, X. I. A. Cheng, and Z. Hong-you, “Blood clinicopathological differences between type I and II ketosis in dairy cows,” Indian J. Anim. Res., vol. 50, no. 5, pp. 753–758, 2016.

J. L. Gordon, S. J. LeBlanc, and T. F. Duffield, “Ketosis treatment in lactating dairy cattle,” Vet. Clin. Food Anim. Pract., vol. 29, no. 2, pp. 433–445, 2013.

F. Vicente et al., “Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages,” Sci. World J., vol. 2014, no. 1, p. 279614, 2014.

L. Andersson and K. Lundström, “Effect of feeding silage with high butyric acid content on ketone body formation and milk yield in postparturient dairy cows,” Zentralblatt für Veterinärmedizin R. A, vol. 32, no. 1‐10, pp. 15–23, 1985.

L. Kung Jr, “Understanding the biology of silage preservation to maximize quality and protect the environment,” in Proceedings, 2010 California Alfalfa & forage symposium and corn/cereal silage conference, 2010, pp. 1–2.

E. Madhesh, R. C. Sundararajan, V. Vijayanand, N. V Rajesh, M. Balagangatharathilagar, and R. B. Vishnurahav, “Therapeutic management of nervous form of ketosis in a dairy cow,” Pharm Innov, vol. 12, no. 10, pp. 1717–1719, 2023.

M. A. C. Lei and J. Simões, “Invited review: ketosis diagnosis and monitoring in high-producing dairy cows,” Dairy, vol. 2, no. 2, pp. 303–325, 2021.

V. K. Meena et al., “Prevalence and clinical findings of ketosis in postparturient cows in and around Bikaner.,” 2022.

B. S. Reddy, B. S. S. Reddy, Y. V. P. Reddy, and R. Vennkatasivakumar, “Nervous form of ketosis in cows and its treatment,” Int. J. Biol. Res, vol. 2, no. 2, pp. 143–144, 2014.

G. Cascone et al., “Subclinical ketosis in dairy herds: Impact of early diagnosis and treatment,” Front. Vet. Sci., vol. 9, p. 895468, 2022.

A. Hubner et al., “Characterization of metabolic profile, health, milk production, and reproductive outcomes of dairy cows diagnosed with concurrent hyperketonemia and hypoglycemia,” J. Dairy Sci., vol. 105, no. 11, pp. 9054–9069, 2022.

F. Enjalbert, M. C. Nicot, C. Bayourthe, and and R. Moncoulon, “Ketone bodies in milk and blood of dairy cows: Relationship between concentrations and utilization for detection of subclinical ketosis,” J. Dairy Sci., vol. 84, no. 3, pp. 583–589, 2001.

P. Gillund, O. Reksen, Y. T. Gröhn, and K. Karlberg, “Body condition related to ketosis and reproductive performance in Norwegian dairy cows,” J. Dairy Sci., vol. 84, no. 6, pp. 1390–1396, 2001.

J. R. Roche, J. K. Kay, N. C. Friggens, J. J. Loor, and D. P. Berry, “Assessing and managing body condition score for the prevention of metabolic disease in dairy cows,” Vet. Clin. Food Anim. Pract., vol. 29, no. 2, pp. 323–336, 2013.

M. Wukadinovich and H. A. Rossow, “Production Responses of Holstein Dairy Cows to a Sodium Propionate Supplement Fed Postpartum to Prevent Hyperketonemia,” Dairy, vol. 4, no. 4, pp. 527–540, 2023.

J. A. A. McArt, D. V Nydam, and G. R. Oetzel, “A field trial on the effect of propylene glycol on displaced abomasum, removal from herd, and reproduction in fresh cows diagnosed with subclinical ketosis,” J. Dairy Sci., vol. 95, no. 5, pp. 2505–2512, 2012.

X. Ji, N. Liu, Y. Wang, K. Ding, S. Huang, and C. Zhang, “Pregnancy toxemia in ewes: a review of molecular metabolic mechanisms and management strategies,” Metabolites, vol. 13, no. 2, p. 149, 2023.

N. R. C. (US). C. on N. R. of S. Ruminants, Nutrient requirements of small ruminants: sheep, goats, cervids, and new world camelids. 中国法制出版社, 2007.

A. Mongini and R. J. Van Saun, “Pregnancy toxemia in sheep and goats,” Vet. Clin. Food Anim. Pract., vol. 39, no. 2, pp. 275–291, 2023.

M. S. Allen, B. J. Bradford, and M. Oba, “Board-invited review: The hepatic oxidation theory of the control of feed intake and its application to ruminants,” J. Anim. Sci., vol. 87, no. 10, pp. 3317–3334, 2009.

J. E. Bayne, “Pregnancy Toxemia Therapeutic Options,” Vet. Clin. Food Anim. Pract., vol. 39, no. 2, pp. 293–305, 2023.

A. Kelay and A. Assefa, “Causes, Control and Prevention Methods of Pregnancy Toxemia in Ewe: A Review,” J. Life Sci. Biomed., vol. 8, no. 4, pp. 69–76, 2018.

A. M. van Vuuren, S. Calsamiglia, and P. Udén, “Rumen health: a 360 analysis,” 2012, Elsevier.

H. M. Golder et al., “Effects of grain, fructose, and histidine on ruminal pH and fermentation products during an induced subacute acidosis protocol,” J. Dairy Sci., vol. 95, no. 4, pp. 1971–1982, 2012.

T. G. Nagaraja and E. C. Titgemeyer, “Ruminal acidosis in beef cattle: the current microbiological and nutritional outlook,” J. Dairy Sci., vol. 90, pp. E17–E38, 2007.

G. R. Oetzel, “Clinical aspects of ruminal acidosis in dairy cattle,” in American Association of Bovine Practitioners Conference Proceedings, 2000, pp. 46–53.

F. N. Owens, D. S. Secrist, W. J. Hill, and D. R. Gill, “Acidosis in cattle: a review,” J. Anim. Sci., vol. 76, no. 1, pp. 275–286, 1998.

R. Stock, “Acidosis in cattle: an overview,” in American Association of Bovine Practitioners Conference Proceedings, 2000, pp. 30–37.

J. B. Russell, “Strategies that ruminal bacteria use to handle excess carbohydrate,” J. Anim. Sci., vol. 76, no. 7, pp. 1955–1963, 1998.

T. L. Huber, “Physiological effects of acidosis on feedlot cattle,” J. Anim. Sci., vol. 43, no. 4, pp. 902–909, 1976.

D. V Rayner, “Gastrointestinal satiety in animals other than man,” Proc. Nutr. Soc., vol. 51, no. 1, pp. 1–6, 1992.

P. Guilloteau, I. Le Huërou‐Luron, J. A. Chayvialle, R. Toullec, R. Zabielski, and J. W. Blum, “Gut regulatory peptides in young cattle and sheep,” J. Vet. Med. Ser. A, vol. 44, no. 1‐10, pp. 1–23, 1997.

A. L. Mordenti, E. Giaretta, L. Campidonico, P. Parazza, and A. Formigoni, “A review regarding the use of molasses in animal nutrition,” Animals, vol. 11, no. 1, p. 115, 2021.

E. Jaramillo-López, M. F. Itza-Ortiz, G. Peraza-Mercado, and J. M. Carrera-Chávez, “Ruminal acidosis: strategies for its control,” Austral J. Vet. Sci., vol. 49, no. 3, pp. 139–148, 2017.

J. B. Ewaschuk, J. M. Naylor, and G. A. Zello, “D-lactate in human and ruminant metabolism,” J. Nutr., vol. 135, no. 7, pp. 1619–1625, 2005.

J. Li, P. Ma, Z. Liu, and J. Xie, “L-and D-Lactate: unveiling their hidden functions in disease and health,” Cell Commun. Signal., vol. 23, no. 1, p. 134, 2025.

J. A. N. Mills et al., “A dynamic mechanistic model of lactic acid metabolism in the rumen,” J. Dairy Sci., vol. 97, no. 4, pp. 2398–2414, 2014.

B. E. Brent and E. E. Bartley, “Thiamin and niacin in the rumen,” J. Anim. Sci., vol. 59, no. 3, pp. 813–822, 1984.

I. J. Lean, H. M. Golder, and M. B. Hall, “Feeding, evaluating, and controlling rumen function,” Vet. Clin. Food Anim. Pract., vol. 30, no. 3, pp. 539–575, 2014.

X. Pan, X. Nan, L. Yang, L. Jiang, and B. Xiong, “Thiamine status, metabolism and application in dairy cows: a review,” Br. J. Nutr., vol. 120, no. 5, pp. 491–499, 2018.

Y. Xu and Z. Ding, “Physiological, biochemical and histopathological effects of fermentative acidosis in ruminant production: a minimal review,” Spanish J. Agric. Res., vol. 9, no. 2 SE-Animal production, pp. 414–422, May 2011, doi: 10.5424/sjar/20110902-177-10.

I. J. Lean, C. T. Westwood, H. M. Golder, and J. J. Vermunt, “Impact of nutrition on lameness and claw health in cattle,” Livest. Sci., vol. 156, no. 1, pp. 71–87, 2013, doi: https://doi.org/10.1016/j.livsci.2013.06.006.

M. S. Hindman, “Metabolic Diseases in Beef Cattle,” Vet. Clin. Food Anim. Pract., vol. 39, no. 2, pp. 337–353, Jul. 2023, doi: 10.1016/j.cvfa.2023.02.011.

M. E. Elmhadi, D. K. Ali, M. K. Khogali, and H. Wang, “Subacute ruminal acidosis in dairy herds: Microbiological and nutritional causes, consequences, and prevention strategies,” Anim. Nutr., vol. 10, pp. 148–155, 2022, doi: https://doi.org/10.1016/j.aninu.2021.12.008.

S. R. van Amstel and J. K. Shearer, “Review of Pododermatitis Circumscripta (Ulceration of the Sole) in Dairy Cows,” J. Vet. Intern. Med., vol. 20, no. 4, pp. 805–811, Jul. 2006, doi: https://doi.org/10.1111/j.1939-1676.2006.tb01789.x.

S. Lean, “Ruminal acidosis—Aetiopathogenesis, prevention and treatment,” Aust. Vet. Assoc, vol. 61, pp. 7–43, 2007.

B. Khorrami, P. Kheirandish, Q. Zebeli, and E. Castillo-Lopez, “Variations in fecal pH and fecal particle size due to changes in dietary starch: Their potential as an on-farm tool for assessing the risk of ruminal acidosis in dairy cattle,” Res. Vet. Sci., vol. 152, pp. 678–686, 2022.

E. Humer et al., “Invited review: Practical feeding management recommendations to mitigate the risk of subacute ruminal acidosis in dairy cattle,” J. Dairy Sci., vol. 101, no. 2, pp. 872–888, 2018.

E. Humer and Q. Zebeli, “Grains in ruminant feeding and potentials to enhance their nutritive and health value by chemical processing,” Anim. Feed Sci. Technol., vol. 226, pp. 133–151, 2017.

R. A. Patton, J. R. Patton, and S. E. Boucher, “Defining ruminal and total-tract starch degradation for adult dairy cattle using in vivo data,” J. Dairy Sci., vol. 95, no. 2, pp. 765–782, 2012.

P. K. Naik, “Bypass fat in dairy ration-a review,” Anim. Nutr. Feed Technol, vol. 13, pp. 147–163, 2013.

Q. Zebeli, D. Mansmann, H. Steingass, and B. N. Ametaj, “Balancing diets for physically effective fibre and ruminally degradable starch: A key to lower the risk of sub-acute rumen acidosis and improve productivity of dairy cattle,” Livest. Sci., vol. 127, no. 1, pp. 1–10, 2010.

K. Boddugari, R. J. Grant, R. Stock, and M. Lewis, “Maximal replacement of forage and concentrate with a new wet corn milling product for lactating dairy cows,” J. Dairy Sci., vol. 84, no. 4, pp. 873–884, 2001.

D. R. Mertens, “Creating a system for meeting the fiber requirements of dairy cows,” J. Dairy Sci., vol. 80, no. 7, pp. 1463–1481, 1997.

J. Heinrichs and P. Kononoff, “Evaluating particle size of forages and TMRs using the new Penn State Forage Particle Separator,” Pennsylvania State Univ. Coll. Agric. Sci. Coop. Ext. DAS, vol. 42, pp. 1–15, 2002.

T. J. DeVries and M. A. G. Von Keyserlingk, “Time of feed delivery affects the feeding and lying patterns of dairy cows,” J. Dairy Sci., vol. 88, no. 2, pp. 625–631, 2005.

J. L. Kleen, G. A. Hooijer, J. Rehage, and J. Noordhuizen, “Subacute ruminal acidosis (SARA): a review,” J. Vet. Med. Ser. A, vol. 50, no. 8, pp. 406–414, 2003.

J. C. Plaizier, D. O. Krause, G. N. Gozho, and B. W. McBride, “Subacute ruminal acidosis in dairy cows: the physiological causes, incidence and consequences,” Vet. J., vol. 176, no. 1, pp. 21–31, 2008.

G. S. Haritha, “Management of Periparturient Disorders,” Periparturient Dis. Cattle, pp. 409–420, 2024.

M. E. Hossain, “Sub-acute ruminal acidosis in dairy cows: Its causes, consequences and preventive measures,” Online J. Anim. Feed Res, vol. 10, no. 1, pp. 302–312, 2020.

C. Hearst et al., “Antibacterial activity of elder (Sambucus nigra L.) flower or berry against hospital pathogens,” J. Med. Plants Res., vol. 4, no. 17, pp. 1805–1809, 2010, doi: 10.5897/JMPR10.147.

E. F. Garrett, K. V Nordlund, W. J. Goodger, and G. R. Oetzel, “A cross-sectional field study investigating the effect of periparturient dietary management on ruminal pH in early lactation dairy cows,” J. Dairy Sci, vol. 80, no. Suppl 1, p. 169, 1997.

W. Z. Yang and K. A. Beauchemin, “Physically effective fiber: method of determination and effects on chewing, ruminal acidosis, and digestion by dairy cows,” J. Dairy Sci., vol. 89, no. 7, pp. 2618–2633, 2006.

R. A. Kohn and T. F. Dunlap, “Calculation of the buffering capacity of bicarbonate in the rumen and in vitro,” J. Anim. Sci., vol. 76, no. 6, pp. 1702–1709, 1998.

Q. Shu, H. S. Gill, R. A. Leng, and J. B. Rowe, “Immunization with a Streptococcus bovis vaccine administered by different routes against lactic acidosis in sheep,” Vet. J., vol. 159, no. 3, pp. 262–269, 2000.

J. Hernández, J. L. Benedito, A. Abuelo, and C. Castillo, “Ruminal acidosis in feedlot: from aetiology to prevention,” Sci. World J., vol. 2014, no. 1, p. 702572, 2014.

A. W. Turner and V. E. Hodgetts, “Buffer systems in the rumen of sheep. II. Buffering properties in relationship to composition.,” Aust. J. Agric. Res., vol. 6, no. 1, pp. 125–144, 1955.

S. K. Sanjay Kumar, S. S. Dagar, A. K. Puniya, and R. C. Upadhyay, “Changes in methane emission, rumen fermentation in response to diet and microbial interactions.,” 2013.

H. Lippke, J. L. Reaves, and N. L. Jacobson, “Rumen pressures associated with the scores of a bloat severity scale,” J. Anim. Sci., vol. 34, no. 1, pp. 171–175, 1972.

G. J. Vogel and C. Parrott, “Mortality survey in feedyards: the incidence of death from digestive, respiratory, and other causes in feedyards on the great plains.,” 1994.

R. C. Backus, Effect of elevated intrarumen pressure on rumen motility, eructation, and ventilation in cattle. University of California, Davis, 1991.

E. Kuusela, Grazing management for Nordic organic dairy farming. Joensuun yliopisto, 2004.

Y. Wang, W. Majak, and T. A. McAllister, “Frothy bloat in ruminants: cause, occurrence, and mitigation strategies,” Anim. Feed Sci. Technol., vol. 172, no. 1–2, pp. 103–114, 2012.

R. E. Howarth, “A review of bloat in cattle,” Can. Vet. J., vol. 16, no. 10, p. 281, 1975.

W. Majak, T. A. McAllister, D. McCartney, K. Stanford, and K. J. Cheng, “Bloat in cattle,” Alberta Agric. Rural Dev. Canada, 2003.

S. Sen, H. P. S. Makkar, and K. Becker, “Alfalfa saponins and their implication in animal nutrition,” J. Agric. Food Chem., vol. 46, no. 1, pp. 131–140, 1998.

E. Azad et al., “Characterization of the rumen and fecal microbiome in bloated and non-bloated cattle grazing alfalfa pastures and subjected to bloat prevention strategies,” Sci. Rep., vol. 9, no. 1, p. 4272, 2019.

G. H. Rajan, C. A. Morris, V. R. Carruthers, R. J. Wilkins, and T. T. Wheeler, “The relative abundance of a salivary protein, bSP30, is correlated with susceptibility to bloat in cattle herds selected for high or low bloat susceptibility,” Anim. Genet., vol. 27, no. 6, pp. 407–414, 1996.

T. Yirdachew and G. Mekonnen, “Review on bloat in cattle,” J. Vet. Med. Anim. Sci, vol. 5, no. 1, p. 1101, 2022.

B. R. Min, W. E. Pinchak, R. C. Anderson, J. D. Fulford, and R. Puchala, “Effects of condensed tannins supplementation level on weight gain and in vitro and in vivo bloat precursors in steers grazing winter wheat,” J. Anim. Sci., vol. 84, no. 9, pp. 2546–2554, 2006.

Y. A. Papadopoulos, E. Charmley, K. B. McRae, A. Farid, and M. A. Price, “Addition of white clover to orchardgrass pasture improves the performance of grazing lambs, but not herbage production,” Can. J. Anim. Sci., vol. 81, no. 4, pp. 517–523, 2001.

B. R. Min, W. E. Pinchak, D. Mathews, and J. D. Fulford, “In vitro rumen fermentation and in vivo bloat dynamics of steers grazing winter wheat to corn oil supplementation,” Anim. Feed Sci. Technol., vol. 133, no. 3–4, pp. 192–205, 2007.

M. Rohde, “The Gram-positive bacterial cell wall,” Microbiol. Spectr., vol. 7, no. 3, pp. 10–1128, 2019.

D. M. Perígolo, F. G. F. de Paula, M. G. Rosmaninho, P. P. de Souza, R. M. Lago, and M. H. Araujo, “Conversion of fatty acids into hydrocarbon fuels based on a sodium carboxylate intermediate,” Catal. Today, vol. 279, pp. 260–266, 2017.

R. C. Pasquali, M. P. Taurozzi, and C. Bregni, “Some considerations about the hydrophilic–lipophilic balance system,” Int. J. Pharm., vol. 356, no. 1–2, pp. 44–51, 2008.

R. A. Zinn, F. N. Owens, and R. A. Ware, “Flaking corn: processing mechanics, quality standards, and impacts on energy availability and performance of feedlot cattle,” J. Anim. Sci., vol. 80, no. 5, pp. 1145–1156, 2002.

T. Ran, A. M. Saleem, K. A. Beauchemin, G. B. Penner, and W. Yang, “Processing index of barley grain and dietary undigested neutral detergent fiber concentration affected chewing behavior, ruminal pH, and total tract nutrient digestibility of heifers fed a high-grain diet,” J. Anim. Sci., vol. 99, no. 1, p. skab011, 2021.

W. Z. Yang, K. A. Beauchemin, and L. M. Rode, “Effects of barley grain processing on extent of digestion and milk production of lactating cows,” J. Dairy Sci., vol. 83, no. 3, pp. 554–568, 2000.

D. W. Bevans, K. A. Beauchemin, K. S. Schwartzkopf-Genswein, J. J. McKinnon, and T. A. McAllister, “Effect of rapid or gradual grain adaptation on subacute acidosis and feed intake by feedlot cattle,” J. Anim. Sci., vol. 83, no. 5, pp. 1116–1132, 2005.

S. Mandawat, R. Singh, V. Galav, S. Kilaka, A. Choudhary, and A. Sewag, “Disorders of forestomach in large ruminants: A review,” Emergent Life Sci. Res., vol. 10, pp. 154–161, 2024.

D. C. Van Metre, G. Fecteau, J. K. House, and L. W. George, “Indigestion of late pregnancy in a cow,” J. Am. Vet. Med. Assoc., vol. 206, no. 5, pp. 625–628, 1995.

A. Bach, M. Baudon, G. Elcoso, J. Viejo, and A. Courillon, “Effects on rumen pH and feed intake of a dietary concentrate challenge in cows fed rations containing pH modulators with different neutralizing capacity,” J. Dairy Sci., vol. 106, no. 7, pp. 4580–4598, 2023.

P. D. Constable, K. W. Hinchcliff, S. H. Done, and W. Grünberg, Veterinary medicine: a textbook of the diseases of cattle, horses, sheep, pigs and goats. Elsevier Health Sciences, 2016.

J. Burgstaller, T. Wittek, and G. W. Smith, “Invited review: Abomasal emptying in calves and its potential influence on gastrointestinal disease,” J. Dairy Sci., vol. 100, no. 1, pp. 17–35, 2017.

R. J. Panciera, M. J. Boileau, and D. L. Step, “Tympany, acidosis, and mural emphysema of the stomach in calves: report of cases and experimental induction,” J. Vet. diagnostic Investig., vol. 19, no. 4, pp. 392–395, 2007.

T. S. Marshall, “Abomasal ulceration and tympany of calves,” Vet. Clin. North Am. Food Anim. Pract., vol. 25, no. 1, pp. 209–220, 2009.

B. L. Roeder, M. M. Chengappa, T. G. Nagaraja, T. B. Avery, and G. A. Kennedy, “Experimental induction of abdominal tympany, abomasitis, and abomasal ulceration by intraruminal inoculation of Clostridium perfringens type A in neonatal calves,” Am. J. Vet. Res., vol. 49, no. 2, pp. 201–207, 1988.

M. Chigerwe and J. V Hagey, “Refractometer assessment of colostral and serum IgG and milk total solids concentrations in dairy cattle,” BMC Vet. Res., vol. 10, pp. 1–6, 2014.

J. F. Mee, “Invited review: Bovine neonatal morbidity and mortality—Causes, risk factors, incidences, sequelae and prevention,” Reprod. Domest. Anim., vol. 58, pp. 15–22, 2023.

T. Wittek, P. D. Constable, and D. E. Morin, “Abomasal impaction in Holstein-Friesian cows: 80 cases (1980–2003),” J. Am. Vet. Med. Assoc., vol. 227, no. 2, pp. 287–291, 2005.

N. K. Singh, S. V Singh, and S. Jaiswal, “Abomasal impaction due to phytobezoariasis in buffalo.,” Vet. Pract., vol. 17, no. 2, 2016.

P. R. Ide and J. H. Henry, “Abomasal abnormalities in dairy cattle: a review of 90 clinical cases,” Can. Vet. J., vol. 5, no. 3, p. 46, 1964.

A. Simsek, S. Sekin, H. Icen, A. Kochan, O. Celik, and T. Yaman, “Abomasal impaction due to sand accumulation in two cows,” Large An. Rev, vol. 21, no. 3, pp. 125–127, 2015.

K. Yong et al., “Abomasum impaction in beef cattle due to high intake of distillers’ grain and treatment options in Southwest China.,” 2021.

D. Yasaswini et al., “Abomasal impaction in buffaloes: Risk factors, clinical indicators, necropsy findings, and histology studies,” Vet. Res. Commun., vol. 47, no. 1, pp. 179–189, 2023.

T. Wittek, K. Tischer, I. Körner, T. Sattler, P. D. Constable, and M. Fürll, “Effect of preoperative erythromycin or dexamethasone/vitamin C on postoperative abomasal emptying rate in dairy cows undergoing surgical correction of abomasal volvulus,” Vet. Surg., vol. 37, no. 6, pp. 537–544, 2008.

S. Van Winden and R. Kuiper, “Left displacement of the abomasum in dairy cattle: recent developments in epidemiological and etiological aspects,” Vet. Res., vol. 34, no. 1, pp. 47–56, 2003.

R. I. N. Gordo, “Contribuição para o estudo do deslocamento do abomaso numa exploração leiteira da região de Montemor-o-Velho,” 2009, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária.

K. Doll, M. Sickinger, and T. Seeger, “New aspects in the pathogenesis of abomasal displacement,” Vet. J., vol. 181, no. 2, pp. 90–96, 2009.

G. Dirksen, “Linksseitige Labmagenverlagerung bei Kalb und Jungrind.,” Tieraerztliche Umschau, vol. 36, 1981.

GEISHAUSER, REICHE, and SCHEMANN, “In vitro motility disorders associated with displaced abomasum in dairy cows,” Neurogastroenterol. Motil., vol. 10, no. 5, pp. 395–401, 1998.

L. A. G. Colturato, C. E. Thomaz, and C. B. da Silva, “Deslocamento de abomaso em bovinos leiteiros,” Pubvet, vol. 15, p. 162, 2020.

V. Wolf, H. Hamann, H. Scholz, and O. Distl, “Einflüsse auf das auftreten von labmagenverlagerungen bei deutschen Holstein kühen,” Dtsch Tierärztl Wschr, vol. 108, pp. 403–408, 2001.

R. Kuiper, “Abomasal diseases,” Bov. Pract., pp. 111–117, 1991.

E. de M. Panelli, “Deslocamento do abomaso à esquerda em bovinos leiteiros: da etiologia ao diagnóstico,” 2014.

N. R. Zwald, K. A. Weigel, Y. M. Chang, R. D. Welper, and J. S. Clay, “Genetic selection for health traits using producer-recorded data. I. Incidence rates, heritability estimates, and sire breeding values,” J. Dairy Sci., vol. 87, no. 12, pp. 4287–4294, 2004.

L. E. Hernández-Castellano, L. L. Hernandez, and R. M. Bruckmaier, “Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows,” Animal, vol. 14, no. 2, pp. 330–338, 2020.

G. R. Oetzel, “An update on hypocalcemia on dairy farms,” in Proceedings of the Four-State Dairy Nutrition and Management Conference, 2012, pp. 80–85.

H. A. Seifi, M. Mohri, A. Ehsani, E. Hosseini, and M. Chamsaz, “Interpretation of bovine serum total calcium: effects of adjustment for albumin and total protein,” Comp. Clin. Path., vol. 14, pp. 155–159, 2005.

J. R. Roche, “The incidence and control of hypocalcaemia in pasture-based systems.,” Acta Vet. Scand. Suppl., vol. 97, pp. 141–144, 2003.

T. A. Reinhardt, J. D. Lippolis, B. J. McCluskey, J. P. Goff, and R. L. Horst, “Prevalence of subclinical hypocalcemia in dairy herds,” Vet. J., vol. 188, no. 1, pp. 122–124, 2011.

T. A. Reinhardt, R. L. Horst, and J. P. Goff, “Calcium, phosphorus, and magnesium homeostasis in ruminants,” Vet. Clin. North Am. Food Anim. Pract., vol. 4, no. 2, pp. 331–350, 1988.

R. L. Horst, J. P. Goff, and T. A. Reinhardt, “Calcium and vitamin D metabolism during lactation,” J. Mammary Gland Biol. Neoplasia, vol. 2, pp. 253–263, 1997.

J. C. Fleet, “Vitamin D-mediated regulation of intestinal calcium absorption,” Nutrients, vol. 14, no. 16, p. 3351, 2022.

P. J. DeGaris and I. J. Lean, “Milk fever in dairy cows: A review of pathophysiology and control principles,” Vet. J., vol. 176, no. 1, pp. 58–69, 2008.

C. Eckermann-Ross, “Hormonal regulation and calcium metabolism in the rabbit,” Vet. Clin. North Am. Exot. Anim. Pract., vol. 11, no. 1, pp. 139–152, 2008.

S. Liu and L. D. Quarles, “How fibroblast growth factor 23 works,” J. Am. Soc. Nephrol., vol. 18, no. 6, pp. 1637–1647, 2007.

J. E. Blau and M. T. Collins, “The PTH-vitamin d-FGF23 axis,” Rev. Endocr. Metab. Disord., vol. 16, pp. 165–174, 2015.

D. D. Bikle, “Vitamin D: production, metabolism and mechanisms of action,” 2015.

J. P. Goff, T. A. Reinhardt, and R. L. Horst, “Enzymes and factors controlling vitamin D metabolism and action in normal and milk fever cows,” J. Dairy Sci., vol. 74, no. 11, pp. 4022–4032, 1991.

D. A. Norman et al., “Jejunal and ileal adaptation to alterations in dietary calcium: changes in calcium and magnesium absorption and pathogenetic role of parathyroid hormone and 1, 25-dihydroxyvitamin D.,” J. Clin. Invest., vol. 67, no. 6, pp. 1599–1603, 1981.

N. Tageldin and A. Martin, “Thyroid, parathyroid hormones and calcium homeostasis,” Anaesth. Intensive Care Med., vol. 21, no. 11, pp. 599–603, 2020.

M. Engel, “Untersuchungen zum Einfluss unterschiedlicher Anionenergänzungen auf die Pansenfermentation, die Spurenelementkonzentration im Serum, die Wasseraufnahme sowie das Harnvolumen bei fistulierten Kühen,” 2006.

R. L. Horst, J. P. Goff, and T. A. Reinhardt, “Advancing age results in reduction of intestinal and bone 1, 25-dihydroxyvitamin D receptor,” Endocrinology, vol. 126, no. 2, pp. 1053–1057, 1990.

C. Martins, M. A. Arcari, K. C. Welter, J. L. Gonçalves, and M. V. dos Santos, “Effect of dietary cation–anion difference on ruminal metabolism, total apparent digestibility, blood and renal acid–base regulation in lactating dairy cows,” animal, vol. 10, no. 1, pp. 64–74, 2016.

J. P. Goff, “Invited review: Mineral absorption mechanisms, mineral interactions that affect acid–base and antioxidant status, and diet considerations to improve mineral status,” J. Dairy Sci., vol. 101, no. 4, pp. 2763–2813, 2018.

J. P. Goff, “The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows,” Vet. J., vol. 176, no. 1, pp. 50–57, 2008.

J. Martín-Tereso and M. W. A. Verstegen, “A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle,” Nutr. Res. Rev., vol. 24, no. 2, pp. 228–243, 2011.

N. Martinez et al., “Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease,” J. Dairy Sci., vol. 95, no. 12, pp. 7158–7172, 2012.

C. F. Arechiga-Flores et al., “Hypocalcemia in the dairy cow. Review,” Rev. Mex. ciencias Pecu., vol. 13, no. 4, pp. 1025–1054, 2022.

J. J. Hodnik, J. Ježek, and J. Starič, “A review of vitamin D and its importance to the health of dairy cattle,” J. Dairy Res., vol. 87, no. S1, pp. 84–87, 2020.

E. Charbonneau, D. Pellerin, and G. R. Oetzel, “Impact of lowering dietary cation-anion difference in nonlactating dairy cows: A meta-analysis,” J. Dairy Sci., vol. 89, no. 2, pp. 537–548, 2006.

K. M. Glosson et al., “Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals,” JDS Commun., vol. 4, no. 6, pp. 449–453, 2023.

L. E. Hernández-Castellano, L. L. Hernandez, H. Sauerwein, and R. M. Bruckmaier, “Endocrine and metabolic changes in transition dairy cows are affected by prepartum infusions of a serotonin precursor,” J. Dairy Sci., vol. 100, no. 6, pp. 5050–5057, 2017.

L. Pinotti, M. Manoni, L. Ferrari, M. Tretola, R. Cazzola, and I. Givens, “The contribution of dietary magnesium in farm animals and human nutrition,” Nutrients, vol. 13, no. 2, p. 509, 2021.

H. Martens and M. Schweigel, “Pathophysiology of grass tetany and other hypomagnesemias: implications for clinical management,” Vet. Clin. North Am. Food Anim. Pract., vol. 16, no. 2, pp. 339–368, 2000.

D. C. da Silva, B. D. Fernandes, J. M. dos S. Lima, B. A. da Silva, G. P. Rodrigues, and E. J. O. de Souza, “Subclinical hypomagnesemia: Prevalence and causes in dairy cows in the semiarid region of the state of Paraíba, Brazil,” Rev. Bras. Saúde e Produção Anim., vol. 21, p. e2121132020, 2020.

J. P. Goff, “Macromineral physiology and application to the feeding of the dairy cow for prevention of milk fever and other periparturient mineral disorders,” Anim. Feed Sci. Technol., vol. 126, no. 3–4, pp. 237–257, 2006.

W. P. Weiss, “Macromineral digestion by lactating dairy cows: factors affecting digestibility of magnesium,” J. Dairy Sci., vol. 87, no. 7, pp. 2167–2171, 2004.

A. Zelal, “Hypomagnesemia tetany in cattle,” Adv. Dairy Res., vol. 5, no. 2, pp. 2–9, 2017.

R. M. McLean and N. X. Wang, “Potassium,” in Advances in food and nutrition research, vol. 96, Elsevier, 2021, pp. 89–121.

J. P. Goff and R. L. Horst, “Role of acid-base physiology on the pathogenesis of parturient hypocalcaemia (milk fever)-the DCAD theory in principal and practice,” 2003.

B. K. R. Dabbir and S. R. Rajavolu, “of Hypokalemia in Cows,” Latest Sci. Find. Rumin. Nutr. Pract. Implement. Res. Pract. Implement., p. 1, 2024.

S. U. Felix, C. N. Pauline, N. Ogunkunle, and A. Lushaikyaa, “Acute Hypokalemia,” Periparturient Dis. Cattle, pp. 213–226, 2024.

S. F. Peek, T. J. Divers, C. Guard, A. Rath, and W. C. Rebhun, “Hypokalemia, muscle weakness, and recumbency in dairy cattle,” Vet Ther, vol. 1, no. 4, pp. 235–244, 2000.

N. Sattler and G. Fecteau, “Hypokalemia syndrome in cattle,” Vet Clin North Am Food Anim Pr., vol. 30, no. 2, pp. 351–357, 2014.

S. Yogeshpriya and P. Selvara, “Mastery of potassium status and their consequences of hypokalemia in dairy cattle,” Shanlax Int. J. Vet. Sci., vol. 5, no. 3, pp. 1–5, 2018.

Z. Toprak Çınar and İ. Şen, “Determination of Potassium Levels in Dairy Cows in the Periparturient Period,” 2022.

J. P. Goff, “Macromineral disorders of the transition cow,” Vet. Clin. Food Anim. Pract., vol. 20, no. 3, pp. 471–494, 2004.

Y. Mehdi and I. Dufrasne, “Selenium in cattle: a review,” Molecules, vol. 21, no. 4, p. 545, 2016.

N. Suttle, Mineral nutrition of livestock. Cabi, 2010.

M. J. Kuhn, “The Potential Role of Vitamin E Analogs as Adjunctive Antioxidant Supplements for Transition Cows,” Dairy, vol. 4, no. 2, pp. 285–299, 2023.

B. Hosnedlova et al., “A summary of new findings on the biological effects of selenium in selected animal species—a critical review,” Int. J. Mol. Sci., vol. 18, no. 10, p. 2209, 2017.

J. Kessler, “Carences en selenium chez les ruminants: mesures prophylactiques.,” Rev. suisse d’agriculture, vol. 25, 1993.

D. R. Khanal and A. P. Knight, “Selenium: its role in livestock health and productivity,” J. Agric. Environ., vol. 11, pp. 101–106, 2010.

K. L. Urschel and E. C. McKenzie, “Nutritional influences on skeletal muscle and muscular disease,” Vet. Clin. Equine Pract., vol. 37, no. 1, pp. 139–175, 2021.

J. Asín et al., “Nutritional wasting disorders in sheep,” Animals, vol. 11, no. 2, p. 501, 2021.

C. J. Finno and E. C. McKenzie, “Vitamin E and Selenium-Related Manifestations of Muscle Disease,” Vet. Clin. Equine Pract., vol. 41, no. 1, pp. 77–93, 2025.

A. MacPherson, “Trace-mineral status of forages.,” 2000.

G. M. Hill and M. C. Shannon, “Copper and zinc nutritional issues for agricultural animal production,” Biol. Trace Elem. Res., vol. 188, pp. 148–159, 2019.

I. K. F. de Sousa et al., “Copper deficiency in sheep with high liver iron accumulation,” Vet. Med. Int., vol. 2012, no. 1, p. 207950, 2012.

D. T. Pal et al., “Effect of copper-and zinc-methionine supplementation on bioavailability, mineral status and tissue concentrations of copper and zinc in ewes,” J. Trace Elem. Med. Biol., vol. 24, no. 2, pp. 89–94, 2010.

L. Byrne and R. A. Murphy, “Relative bioavailability of trace minerals in production animal nutrition: A review,” Animals, vol. 12, no. 15, p. 1981, 2022.

M. A. Al-Bayati, D. A. Jamil, and H. A. Al-Aubaidy, “Cardiovascular effects of copper deficiency on activity of superoxide dismutase in diabetic nephropathy,” N. Am. J. Med. Sci., vol. 7, no. 2, p. 41, 2015.

M. Rondanelli et al., “Copper as dietary supplement for bone metabolism: a review,” Nutrients, vol. 13, no. 7, p. 2246, 2021.

O. K. S. Sudan, S. Arkaweet, and A. C. Trinidad, “Review on Copper’s Functional Roles, Copper X Mineral Interactions Affecting Absorption, Tissue Storage, and Cu Deficiency Swayback of Small Ruminants”.

A. A. Saka, O. S. Sowande, A. O. Yusuf, and F. O. Ogunleke, “Importance of dietary copper supplementation in ruminant production: A review,” Niger. J. Anim. Prod., vol. 49, no. 2, pp. 235–245, 2022.

A. O. Adogwa, T. Alleyne, and A. Mohammed, “Degenerative changes in the cerebral cortex in swayback disease lambs,” Alzheimer’s Dis. Rev., vol. 4, pp. 19–22, 1999.

M. Borobia et al., “Copper poisoning, a deadly hazard for sheep,” Animals, vol. 12, no. 18, p. 2388, 2022.