Nanoteknolojik Ürünlerin Çevresel Etkileri

Özet

Nanoteknolojinin hızla gelişmesiyle birlikte nanopartiküller tarım, tıp, enerji ve kozmetik başta olmak üzere pek çok endüstri alanında yaygın olarak kullanılmaktadır. Bu kullanım, nanopartiküllerin çevreye beklenmedik yollarla yayılmasına ve toprak, su ve hava ortamlarında birikmesine neden olmaktadır. Nanopartiküllerin çevresel davranışları, kimyasal yapıları, boyutları, yüzey özellikleri ve çevresel koşullara bağlı olarak değişiklik göstermekte; biyolojik sistemlerle etkileşimlerinde kompleks toksikolojik sonuçlar ortaya çıkarmaktadır. Sucul ekosistemlerde yaşayan algler, kabuklular, balıklar gibi organizmalar nanopartiküllere doğrudan maruz kalması sonucunda oksidatif stres ve doku hasarı gibi olumsuz etkiler meydana getirmektedir. Toprak ekosistemlerinde yaşayan mikroorganizmalar, solucanlar ve nematodlar gibi organizmalar nanopartiküllerin biyolojik etkilerine doğrudan maruz kalmakta ve bu maruziyet sonucunda oksidatif stres, büyüme geriliği, üreme azalması ve genetik hasar gibi olumsuz biyolojik etkiler gözlenmektedir. Bu bölümde, nanopartiküllerin çevresel salınım ve dağılım özellikleri ile sucul ve toprak organizmaları üzerindeki etkileri tartışılmıştır. Ayrıca, nanopartiküllerin çevre sağlığı açısından uzun vadeli etkilerini değerlendirmek amacıyla ileri araştırmalara ihtiyaç duyulduğu vurgulanmaktadır.

With the rapid development of nanotechnology, nanoparticles are widely used in many industrial fields, especially in agriculture, medicine, energy and cosmetics. This use causes nanoparticles to spread into the environment in unexpected ways and to accumulate in soil, water and air environments. The environmental behaviors of nanoparticles vary depending on their chemical structures, sizes, surface properties and environmental conditions; and their interactions with biological systems result in complex toxicological results. Organisms such as algae, crustaceans and fish living in aquatic ecosystems experience adverse effects such as oxidative stress and tissue damage because of direct exposure to nanoparticles. Organisms such as microorganisms, worms and nematodes living in soil ecosystems are directly exposed to the biological effects of nanoparticles and because of this exposure, adverse biological effects such as oxidative stress, growth retardation, reduced reproduction and genetic damage are observed. In this section, the environmental release and distribution properties of nanoparticles and their effects on aquatic and soil organisms are discussed. In addition, it is emphasized that further research is needed to evaluate the long-term effects of nanoparticles in terms of environmental health.

Referanslar

Moore JD, Stegemeier JP, Bibby K, et al. Impacts of pristine and transformed Ag and Cu engineered nanomaterials on surficial sediment microbial communities appear short-lived. Environmental Science & Technology. 2016; 50: 2641-2651.

Babatunde DE, Denwigwe IH, Babatunde OM, et al. Environmental and Societal Impact of Nanotechnology. IEEE Access. 2020; 8: 4640-4667. doi: 10.1109/ACCESS.2019.2961513

Biswas P, Wu CY. Nanoparticles and the environment. Journal of the Air & Waste Management Association. 2005;55(6):708-46. doi: 10.1080/10473289.2005.10464656.

Keller AA, McFerran S, Lazareva A, et al. Global life cycle releases of engineered nanomaterials. Journal of Nanoparticle Research. 2013;15:1692. doi: 10.1007/s11051-013-1692-4

Benn T, Westerhoff P. Nanoparticle silver released into water from commercially available sock fabrics. Environmental Science & Technology. 2008;42(11):4133–4139. doi: 10.1021/es7032718

Gottschalk F, Nowack B. The release of engineered nanomaterials to the environment. Journal of Environmental Monitoring. 2011; 13(5), 1145–1155. doi: 10.1039/C0EM00547A

Nowack B, Bucheli TD. Occurrence, behavior and effects of nanoparticles in the environment. Environmental Pollution. 2007; 150(1): 5–22. doi: 10.1016/j.envpol.2007.06.006

Hyung H, Kim JH. Natural organic matter (NOM) adsorption to multi-walled carbon nanotubes: Effect of NOM characteristics and water chemistry. Environmental Science & Technology, 2009; 43(15): 6296–6302. doi: 10.1021/es702916h

Cornelis G, Hund-Rinke K, Kuhlbusch T. Fate and Bioavailability of Engineered Nanoparticles in Soils: A Review. Critical Reviews in Environmental Science and Technology. 2014; 44(24): 2720-2764. doi: 10.1080/10643389.2013.829767

Lowry GV, Gregory KB, Apte SC. Transformations of nanomaterials in the environment. Environmental Science & Technology. 2012; 46(13): 6893–6899. doi: 10.1021/es300839e

Fabrega J, Fawcett SR, Renshaw JC, et al. Silver nanoparticle impact on bacterial growth: Effect of pH, concentration, and organic matter. Environmental Science & Technology. 2011; 45(22): 10362-10367. doi: 10.1021/es803259g

Maurer-Jones MA, Gunsolus IL, Murphy CJ, et al. Toxicity of engineered nanoparticles in the environment. Analytical Chemistry. 2013; 85(6): 3036–3049. doi: 10.1021/ac303636s

Klaine SJ, Alvarez PJJ, Batley GE, et al. Nanomaterials in the environment: Behavior, fate, bioavailability, and effects. Environmental Toxicology and Chemistry, 2008; 27(9): 1825–1851. doi: 10.1897/08-090.1

Gottschalk F, Sun T, Nowack B. Environmental concentrations of engineered nanomaterials: Review of modeling and analytical studies. Environmental Pollution. 2013; 181: 287-300. doi: 10.1016/j.envpol.2013.06.003

Petersen EJ, Pinto RA, Zhang L, et al. Bioaccumulation of multiwalled carbon nanotubes in Eisenia foetida. Environmental Science & Technology. 2011; 45(8): 3718–3724. doi: 10.1021/es071366f

Wigginton NS, Haus KL, Hochella Jr, MF. Aquatic environmental nanoparticles. Journal of Environmental Monitoring. 2007; 9(12): 1306-1316. doi: 0.1016/j.psep.2019.08.014

Handy RD, Owen R, Valsemi-Jones E. The ecotoxicology of nanoparticles and nanomaterials: Current status, knowledge gaps, challenges, and future needs. Ecotoxicology, 2008; 17(4): 287–314. doi: 10.1007/s10646-008-0206-0

Nel A, Xia T, Mädler L, et al. Toxic potential of materials at the nanolevel. Science. 2006; 311(5761): 622–627. doi: 10.1126/science.1114397

Li N, Sioutas C, Cho A, et al. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environmental Health Perspectives. 2008; 116(4): 441–447. doi: 10.1289/ehp.6000

Zha S, Rong J, Guan X, et al. (2019). Immunotoxicity of four nanoparticles to a marine bivalve species, Tegillarca granosa. Journal of Hazardous Materials. 2019; 377: 237-248. doi: 10.1016/j.jhazmat.2019.05.071

Manusadžianas L, Caillet C, Fachetti L, et al. Toxicity of copper oxide nanoparticle suspensions to aquatic biota. Environmental Toxicology and Chemistry. 2012; 31(1): 108-114. doi: 10.1002/etc.715

Sohn EK, Johari SA, Kim TG, et al. Aquatic toxicity comparison of silver nanoparticles and silver nanowires. BioMed Research International. 2015; (1): 893049. doi: 10.1155/2015/893049

Gonçalves SF, Pavlaki DM, Lopes R, Effects of silver nanoparticles on the freshwater snail Physa acuta: the role of test media and snails’ life cycle stage. Environmental Toxicology and Chemistry. 2017; 36(1): 243-253. doi: 10.1002/etc.3532

Pham TL. Toxicity of silver nanoparticles to tropical microalgae Scenedesmus acuminatus, Chaetoceros gracilis and crustacean Daphnia lumholtzi. Turkish Journal of Fisheries and Aquatic Sciences. 2019; 19(12): 1009-1016. doi: 10.4194/1303-2712-v19_12_03

Kocer ZI, Ayışığı M, Haseki S, et al. Phyto-Synthesized Silver Nanoparticle Toxicity Effect on Aquatic Plant Lemna minor L. Avrupa Bilim ve Teknoloji Dergisi. 2021; (27): 1087-1094. doi: 10.31590/ejosat.980995

Auclair J, Gagné F. Shape-dependent toxicity of silver nanoparticles on freshwater cnidarians. Nanomaterials. 2022; 12(18): 3107. doi: 10.3390/nano12183107

Medina-Ramírez IE, Rodríguez-Padilla AD, Pérez CEH, et al. ZnO nanoparticles and Cu2+ enhanced toxicity in acute rather than chronic exposure of the freshwater rotifer Lecane papuana. International Journal of Aquatic Biology. 2022; 10(6): 489-503. doi: 10.22034/ijab.v10i6.1708

Gomes T, Pinheiro JP, Cancio I, et al. Effects of copper nanoparticles exposure in the mussel Mytilus galloprovincialis. Environmental Science & Technology. 2011; 45(21): 9356-9362. doi: 10.1021/es200955s

Faria M, Navas JM, Soares AM, et al. Oxidative stress effects of titanium dioxide nanoparticle aggregates in zebrafish embryos. Science of The Total Environment. 2014; 470: 379-389. doi: 10.1016/j.scitotenv.2013.09.055

Noureen A, Jabeen F, Tabish TA, et al. Histopathological changes and antioxidant responses in common carp (Cyprinus carpio) exposed to copper nanoparticles. Drug and Chemical Toxicology, 2021; 44(4): 372-379. doi: 10.1080/01480545.2019.1606233

Şimşek İ, Arslan P, Günal AÇ, et al. Acute and Chonic Effects of Silver Nanoparticles (AgNPs) on Unio delicatus. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi. 2024; 13(1): 101-106. doi: 10.17798/bitlisfen.1351240

Jovanović B, Palić D. Immunotoxicology of non-functionalized engineered nanoparticles in aquatic organisms with special emphasis on fish—Review of current knowledge, gap identification, and call for further research. Aquatic Toxicology, 2012; 118: 141-151. doi: 10.1016/j.aquatox.2012.04.005

Jayaseelan C, Rahuman AA, Ramkumar R, et al. Effect of sub-acute exposure to nickel nanoparticles on oxidative stress and histopathological changes in Mozambique tilapia, Oreochromis mossambicus. Ecotoxicology and Environmental Safety. 2014; 107: 220-228. doi: 10.1016/j.ecoenv.2014.06.012

Johari SA, Kalbassi MR, Yu IJ, et al. Chronic effect of waterborne silver nanoparticles on rainbow trout (Oncorhynchus mykiss): histopathology and bioaccumulation. Comparative Clinical Pathology. 2015; 24: 995-1007. doi: 10.1007/s00580-014-2019-2

Fol MF, Abdel-Ghaffar FA, Hassan HAM, et al. Oxidative stress, histopathological and genotoxicity of copper oxide nanoparticles in Biomphalaria alexandrina snail. Scientific Reports. 2014; 14(1): 25187. doi: 10.1038/s41598-024-74439-9

Tourinho PS, van Gestel CAM, Lofts S, et al. Metal-based nanoparticles in soil: Fate, behavior, and effects on soil invertebrates. Environmental Toxicology and Chemistry. 2012; 31(8): 1679–1692. doi: 10.1002/etc.1880

Ma H, Bertsch PM, Glenn TC, et al. Toxicity of manufactured zinc oxide nanoparticles in the nematode Caenorhabditis elegans. Environmental Toxicology and Chemistry. 2009; 28:1324– 1330. doi: 10.1897/08-262.1

Kool PL, Diez Ortiz M, van Gestel CAM. Chronic toxicity of ZnO nanoparticles, non-nano ZnO and ZnCl2 to Folsomia candida (Collembola) in relation to bioavailability in soil. Environmental Pollution. 2011; 159: 2713–27. doi: 10.1016/j.envpol.2011.05.021

Shoults-Wilson WA, Reinsch BC, Tsyusko OV, et al. Role of particle size and soil type in toxicity of silver nanoparticles to earthworms. The Soil Science Society of America .2011; 75: 365–377. doi: 10.2136/sssaj2010.0127nps

Diez-Ortiz M, Lahive E, George S, et al. Short-term soil bioassays may not reveal the full toxicity potential for nanomaterials; bioavailability and toxicity of silver ions (AgNO3) and silver nanoparticles to earthworm Eisenia fetida in long-term aged soils. Environmental Pollution. 2015; 203: 191-198. doi: 10.1016/j.envpol.2015.03.033

Santos FC, Gomes SI, Scott‐Fordsmand JJ, et al. Hazard assessment of nickel nanoparticles in soil—The use of a full life cycle test with Enchytraeus crypticus. Environmental Toxicology and Chemistry. 2017; 36(11): 2934-2941. doi: 10.1002/etc.3853

Ge Y, Schimel JP, Holden PA. Evidence for negative effects of TiO₂ and ZnO nanoparticles on soil bacterial communities. Environmental Science & Technology. 2011; 45(4): 1659–1664. doi: 10.1021/es103040t

Lin D, Xing B. Phytotoxicity of nanoparticles: Inhibition of seed germination and root growth. Environmental Pollution. 2007; 150(2): 243–250. doi: 10.1016/j.envpol.2007.01.016.

OECD (2012). Guidance on Sample Preparation and Dosimetry for the Safety Testing of Manufactured Nanomaterials. OECD Series on the Safety of Manufactured Nanomaterials No. 36.

Handy RD, Owen R, Valsami-Jones E. The ecotoxicology of nanoparticles and nanomaterials: Current status, knowledge gaps, challenges, and future needs. Ecotoxicology. 2008; 17(4): 287–314. doi: 10.1007/s10646-008-0206-0

Zhu X, Chang Y, Chen Y. Toxicity and bioaccumulation of TiO₂ nanoparticle aggregates in Daphnia magna. Chemosphere. 2010; 78(3): 209–215. doi: 10.1016/j.chemosphere.2009.11.013

Johnston BD, Scown TM, Moger J, et al. Bioavailability of nanoscale metal oxides TiO₂, CeO₂, and ZnO to fish. Environmental Science & Technology. 2010; 44(3): 1144–1151. doi: 10.1021/es901971a

Lee WM, Yoon SJ, Shin YJ, et al. Trophic transfer of gold nanoparticles from Euglena gracilis or Chlamydomonas reinhardtii to Daphnia magna. Environmental Pollution. 2015; 201: 10-16. doi: 10.1016/j.envpol.2015.02.021

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