Kampilobakteriyozis

Özet

Kampilobakteriyozis, özellikle Campylobacter jejuni ve Campylobacter coli türlerinin neden olduğu hem gelişmiş hem de gelişmekte olan ülkelerde yaygın görülen zoonotik bir enfeksiyondur. Kanatlı hayvanlar, bu bakterilerin en yaygın rezervuarıdır ve kontamine gıda, özellikle tavuk eti, ana bulaşma yoludur. Tavuklar genellikle asemptomatik taşıyıcıdır, ancak bazı durumlarda karaciğer ve bağırsaklarda hasar görülebilir. Bakteri, bağırsak mukozasına yapışarak kolonizasyon sağlar ve toksinlerle mukozal bütünlüğü bozarak ishal gibi semptomlara yol açar. Kampilobakteriyozis tanısı için dışkı, rektal sürüntü ve gıda örneklerinden yapılan mikrobiyolojik kültürler ve PCR gibi moleküler yöntemler yaygın olarak uygulanmaktadır. Campylobacter enfeksiyonlarının kontrolü için çiftlik düzeyinde biyogüvenlik önlemleri ve tüketicilerin eğitimi önemlidir. Antibiyotik direnci nedeniyle doğal alternatifler (prebiyotik ve probiyotikler, uçucu yağlar, bakteriyosinler ve bakteriyofafların kullanımı) umut vaat eden stratejilerdir. Gıda güvenliği standartlarının iyileştirilmesi, bulaşma zincirinin kırılmasında kritik bir rol oynar. Kanatlı kümes hayvanlarında çok çeşitli aşılama stratejilerine yönelik araştırmalar yapılmış olmasına rağmen kampilobakteriyozise karşı hâlihazırda geliştirilmiş ticari bir aşı mevcut değildir.

Referanslar

Akinmolayan TA, Alao JO, Wilkie ED, et al. Strategies for controlling Campylobacter in poultry production: A comprehensive review of challenges and potential solutions. South Asian Journal of Research in Microbiology. 2023;17(2): 50–61.

Al Hakeem WG, Fathima S, Shanmugasundaram R, et al. Campylobacter jejuni in poultry: Pathogenesis and control strategies. Microorganisms. 2022;10(11): 2134. doi:10.3390/microorganisms10112134

Anonim. European Commission: Directorate-General for Health and Food Safety, Mitigation measures in place for Campylobacter spp. in poultry – Overview report, Publications Office, 2017, https://data.europa.eu/doi/10.2875/894648

Anonim. https://hsgm.saglik.gov.tr/depo/Mevzuat/Genelgeler/2015-18_Bulasici_Hastaliklarin_Ihbar_ ve_Bildirim_Sistemi_Genelgesi.pdf. 2024. Son erişim tarihi: 15.12.2024

Carrillo CL, Atterbury RJ, El-Shibiny A, et al. Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens. Applied in Environmental Microbiology. 2005;71: 6554–6563. doi:10.1128/AEM.71.11.6554-6563.2005

CDC Foodborne Diseases Active Surveillance Network (FoodNet) (2019) Foodborne Diseases Active Surveillance Network (FoodNet). https://www.cdc.gov/foodnet/reports/cidt-questions-and-answers-2015.html. Son erişim tarihi: 10.12.2024.

Chiba M, Miri S, Yousuf B, et al. Dual bacteriocin and extracellular vesicle-mediated inhibition of Campylobacter jejuni by the potential probiotic candidate Ligilactobacillus salivarius UO.C249. Applied in Environmental Microbiology. 2024;90(8): e0084524. doi:10.1128/aem.00845-24

EFSA (European Food Safety Authority) and ECDC (European Centre for Disease Prevention and Control), 2020. The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2017/2018. EFSA Journal. 2020;18(3): 6007. doi:10.2903/j.efsa.2020.6007

El-Saadony MT, Saad AM, Yang T, et al. Avian campylobacteriosis, prevalence, sources, hazards, antibiotic resistance, poultry meat contamination, and control measures: a comprehensive review. Poultry Science. 2023;102(9): 102786. doi:10.1016/j.psj.2023.102786

European Centre for Disease Prevention and Control. Campylobacteriosis. In: ECDC. Annual Epidemiological Report for 2022. Stockholm: ECDC; 2024.

European Food Safety Authority and European Centre for Disease Prevention and Control. The European Union One Health 2022 Zoonoses Report. EFSA Journal. 2023;21(12): e8442. doi:10.2903/j.efsa.2023.8442

Franco J, Bénejat L, Ducournau A, et al. Evaluation of Campylobacter Quik Chek™ rapid membrane enzyme immunoassay to detect Campylobacter spp. antigen in stool samples. Gut Pathogens. 2021;13: 4. doi:10.1186/s13099-021-00400-0

Ghareeb K, Awad WA, Mohnl M, et al. Evaluating the efficacy of an avian-specific probiotic to reduce the colonization of Campylobacter jejuni in broiler chickens. Poultry Science. 2012;91: 1825–1832. doi:10.3382/ps.2012-02168

Givanoudi S, Cornelis P, Rasschaert G, et al. Selective Campylobacter detection and quantification in poultry: A sensor tool for detecting the cause of a common zoonosis at its source. Sensors and Actuators B: Chemical. 2021;332: 129484. doi:10.1016/j.snb.2021.129484

Hong Y, Berrang ME, Liu T, et al. Rapid detection of Campylobacter coli, C. jejuni, and Salmonella enterica on poultry carcasses by using PCR-enzyme-linked immunosorbent assay. Applied and Environmental Microbiology. 2003;69(6): 3492–3499. doi:10.1128/AEM.69.6.3492-3499.2003

International Standards:ISO10272-1. Microbiology of the food chain -Horizontal method for detection and enumeration of Campylobacter spp. Part1: Detection method https://cdn.standards.iteh.ai/samples/63225/1f39e47874ec4e24a6353d992eb54b82/ISO-10272-1-2017.pdf

International Standards:ISO10272-2. Microbiology of the food chain -Horizontal method for detection and enumeration of Campylobacter spp. Part 2: Colony-count technique https://cdn.standards.iteh.ai/samples/63228/52bcdbb727d84c90875b1152a57e575e/ISO-10272-2-2017.pdf

Lilja L, Hänninen ML. Evaluation of a commercial automated ELISA and PCR-method for rapid detection and identification of Campylobacter jejuni and C. coli in poultry products. Food Microbiology. 2001;18: 205–209. doi:10.1006/fmic.2000.0392.

Liu L, Hussain SK, Miller RS, et al. Efficacy of mini VIDAS for the detection of Campylobacter spp. from retail broiler meat enriched in Bolton broth, with or without the supplementation of blood. Journal of Food Protection. 2009;72(11):2428–2432. doi:10.4315/0362-028x-72.11.2428

Liu X, Adams LJ, Zeng X, et al. Evaluation of in ovo vaccination of DNA vaccines for Campylobacter control in broiler chickens. Vaccine. 2019;37(29): 3785-3792. doi:10.1016/j.vaccine.2019.05.082.

Mavri A, Smole Možina S. Development of antimicrobial resistance in Campylobacter jejuni and Campylobacter coli adapted to biocides. International Journal of Food Microbiology. 2013;160(3): 304–312. doi:10.1016/j.ijfoodmic ro.2012.11.006

Mayr AM, Lick S, Bauer J, et al. Rapid detection and differentiation of Campylobacter jejuni, Campylobacter coli and Campylobacter lari in food, using multiplex real-time PCR. Journal of Food Protection. 2010;73: 241–250.

Myintzaw P, Jaiswal AK, Jaiswal S. A review on campylobacteriosis associated with poultry meat consumption. Food Reviews International. 2023;39: 2107–2121. doi:10.1080/87559129.2021.1942487

Ngulukun S. Taxonomy and physiological characteristics of Campylobacter spp. G. Klein (Ed.), Campylobacter features, detection, and prevention of foodborne disease, Academic Press. 2017; pp. 41–60.

Oren A, Garrity GM. Valid publication of the names of forty-two phyla of prokaryotes. International Journal of Systematic and Evolutionary Microbiology. 2021;71: 5056.

Parte AC. Campylobacter: LPSN-List of Prokaryotic names with Standing in Nomenclature (bacterio.net), 20 years on. International Journal of Systematic and Evolutionary Microbiology. 2018;68(6): 1825–1829. doi:10.1099/ijsem.0.002786

Poppert S, Haas M, Yildiz T, et al. Identification of thermotolerant Campylobacter species by fluorescence in situ hybridization. Journal of Clinical Microbiology. 2008;46(6): 2133–2136. doi:10.1128/JCM.01512-07

Pumtang-On P, Mahony TJ, Hill RA, et al. A systematic review of Campylobacter jejuni vaccine candidates for chickens. Microorganisms. 2021;9(2): 397. doi:10.3390/microorganisms9020397

Ramabu S, Boxall N, Madie P, et al. Some potential sources for transmission of Campylobacter jejuni to broiler chickens. Letters in Applied Microbiology. 2004;39: 252–256. doi:10.1111/j.1472-765X.2004.01573.x

Resmi Gazete. https://www.tarimorman.gov.tr/HHGM/Haber/104/Insanlarda-Belirli-Enfeksiyonlarin-Tedavisi-Icin-Ayrilmis-Antimikrobiyallerin-Veya-Antimikrobiyal-Gruplarinin-Belirlenmesi-Hakkinda-Teblig-Yayimlanmistir

Resmi Gazete. Yem Katkıları ve Premikslerin Üretimi, İthalatı, İhracatı, Satışı ve Kullanımı Hakkında Tebliğde Değişiklik Yapılmasına Dair Tebliğ. Tarım ve Köyişleri Bakanlığı. 21 Ocak 2006. Sayı: 26056 Tebliğ No: 2006/1.

Sadek SAS, Shaapan RM, Barakat AMA. Campylobacteriosis in poultry: A review. Journal of World Poultry Research. 2023;13(2): 168–179. doi:10.36380/jwpr.2023.19

Sayers EW, Beck J, Bolton EE, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Research. 2024;5(52): D33–D43. doi:10.1093/nar/gkad1044.

Silva J, Leite D, Fernandes M, et al. Campylobacter spp. as a foodborne pathogen: A review. Frontiers in Microbiology. 2011;27: 200. doi:10.3389/fmicb.2011.00200

Śmiałek M, Kowalczyk J, Koncicki A. The use of probiotics in the reduction of Campylobacter spp. prevalence in poultry. Animals. 2021;11: 1355. doi:10.3390/ani11051355

Steele TW, Mcdermott SN. The use of membrane filters applied directly to the surface of agar plates for the isolation of Campylobacter jejuni from feces. Pathology. 1984;16: 263–265.

Ushanov L, Lasareishvili B, Janashia I, et al. Application of Campylobacter jejuni phages: Challenges and perspectives. Animals. 2020;10: 279. doi:10.3390/ani10020279

Wassenaar TM, Blaser MJ. Pathophysiology of Campylobacter jejuni infections of humans. Microbes and Infection. 1999;1: 1023–1033. doi:10.1016/S1286-4579(99)80520-6

World Health Organization. Campylobacter. https://www.who.int/news-room/fact-sheets/detail/Campylobacter. Son erişim tarihi: 15.12.2024

Gelecek

22 Ağustos 2025

Lisans

Lisans