Ortodontide Genetik Bilgi & Klinik Uygulamadaki Yeri

Collins FS, Morgan M, Patrinos A. The Human Genome Project: lessons from large-scale biology. Science. 2003;300(5617):286-90.

Carlson DS, editor Theories of craniofacial growth in the postgenomic era. Seminars in Orthodontics; 2005: Elsevier.

Gutiérrez SJ, Gómez M, Rey JA, Ochoa M, Gutiérrez SM, Prieto JC. Polymorphisms of the noggin gene and mandibular micrognathia: a first approximation. Acta Odontológica Latinoamericana. 2010;23(1):13-9.

El Chekie MR, Nemer G, Khalil A, Macari AT, Ghafari JG. Novel genes linked to Class II Division 1 malocclusion with mandibular micrognathism. American Journal of Orthodontics and Dentofacial Orthopedics. 2023;163(5):667-76. e3.

Yamaguchi T, Park S, Narita A, Maki K, Inoue I. Genome-wide linkage analysis of mandibular prognathism in Korean and Japanese patients. Journal of dental research. 2005;84(3):255-9.

Genno PG, Nemer GM, Eddine SBZ, Macari AT, Ghafari JG. Three novel genes tied to mandibular prognathism in eastern Mediterranean families. American Journal of Orthodontics and Dentofacial Orthopedics. 2019;156(1):104-12. e3.

Townsend G, Hughes T, Luciano M, Bockmann M, Brook A. Genetic and environmental influences on human dental variation: a critical evaluation of studies involving twins. Archives of Oral Biology. 2009;54:S45-S51.

Bergendal B, Klar J, Stecksén‐Blicks C, Norderyd J, Dahl N. Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes. American Journal of Medical Genetics Part A. 2011;155(7):1616-22.

van den Boogaard M, Creton M, Bronkhorst Y, van der Hout A, Hennekam E, Lindhout D, et al. WNT10A, rather than MSX1 is a major cause of non-syndromic hypodontia. MSX1 in relation to clefting, hypodontia and hydrocephaly in humans. 2012;49(5):149.

Detlefsen J. Intrinsic or hereditary factors versus extrinsic or environmental factors in the determination of tooth and oral peculiarities. JD Res. 1928;8:419.

Decker E, Stellzig-Eisenhauer A, Fiebig BS, Rau C, Kress W, Saar K, et al. PTHR1 loss-of-function mutations in familial, nonsyndromic primary failure of tooth eruption. The American Journal of Human Genetics. 2008;83(6):781-6.

Šidlauskas M, Šalomskienė L, Andriuškevičiūtė I, Šidlauskienė M, Labanauskas Ž, Vasiliauskas A, et al. Heritability of mandibular cephalometric variables in twins with completed craniofacial growth. European journal of orthodontics. 2016;38(5):493-502.

Statello L, Guo C-J, Chen L-L, Huarte M. Gene regulation by long non-coding RNAs and its biological functions. Nature reviews Molecular cell biology. 2021;22(2):96-118.

Ghafari J. Therapeutic and developmental maxillary orthopedics: evaluation of effects and limitations. Biological Mechanisms of Tooth Eruption, Resorption, and Replacement by Implants: The Harvard Society for the Advancement of Orthodontics Boston; 2004. p. 167-81.

Ghafari JG, Haddad RV, Saadeh ME. Class III malocclusion—the evidence on diagnosis and treatment. Evidence‐Based Orthodontics. 2011:247-80.

Huh A, Horton MJ, Cuenco KT, Raoul G, Rowlerson AM, Ferri J, et al. Epigenetic influence of KAT6B and HDAC4 in the development of skeletal malocclusion. American Journal of Orthodontics and Dentofacial Orthopedics. 2013;144(4):568-76.

Hartsfield Jr JK, Jacob GJ, Morford LA, editors. Heredity, genetics and orthodontics: How much has this research really helped? Seminars in Orthodontics; 2017: Elsevier.

Klein Y, Fleissig O, Polak D, Barenholz Y, Mandelboim O, Chaushu S. Immunorthodontics: in vivo gene expression of orthodontic tooth movement. Scientific reports. 2020;10(1):8172.

Neela PK, Atteeri A, Mamillapalli PK, Sesham VM, Keesara S, Chandra J, et al. Genetics of dentofacial and orthodontic abnormalities. Global medical genetics. 2020;7(04):095-100.

Mostowska A, Biedziak B, Jagodzinski PP. Axis inhibition protein 2 (AXIN2) polymorphisms may be a risk factor for selective tooth agenesis. Journal of human genetics. 2006;51(3):262-6.

Peters H, Balling R. Teeth: where and how to make them. Trends in Genetics. 1999;15(2):59-65.

Paixao-Cortes VR, Meyer D, Pereira TV, Mazières S, Elion J, Krishnamoorthy R, et al. Genetic variation among major human geographic groups supports a peculiar evolutionary trend in PAX9. PLoS One. 2011;6(1):e15656.

Stockton DW, Das P, Goldenberg M, D'Souza RN, Patel PI. Mutation of PAX9 is associated with oligodontia. Nature genetics. 2000;24(1):18-9.

Nieminen P, Arte S, Tanner D, Paulin L, Alaluusua S, Thesleff I, et al. Identification of a nonsense mutation in the PAX9 gene in molar oligodontia. European Journal of Human Genetics. 2001;9(10):743-6.

Das P, Stockton DW, Bauer C, Shaffer LG, D’Souza RN, Wright TJ, et al. Haploinsufficiency of PAX9 is associated with autosomal dominant hypodontia. Human genetics. 2002;110:371-6.

Mostowska A, Kobielak A, Trzeciak WH. Molecular basis of non‐syndromic tooth agenesis: mutations of MSX1 and PAX9 reflect their role in patterning human dentition. European journal of oral sciences. 2003;111(5):365-70.

Stoczyńska E, Pawłowska E, Popławski T, Szczepańska J, Błasiak J. Rola białek PAX9 i MSX1 w rozwoju i agenezji zębów. J Stomatol. 2010;63:310-9.

Neubüser A, Peters H, Balling R, Martin GR. Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation. Cell. 1997;90(2):247-55.

Sharpe PT. Homeobox genes and orofacial development. Connective Tissue Research. 1995;32(1-4):17-25.

Huelsken J, Birchmeier W. New aspects of Wnt signaling pathways in higher vertebrates. Current opinion in genetics & development. 2001;11(5):547-53.

Giles RH, Van Es JH, Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer. 2003;1653(1):1-24.

Seidensticker MJ, Behrens J. Biochemical interactions in the wnt pathway. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research. 2000;1495(2):168-82.

Yamamoto H, Kishida S, Uochi T, Ikeda S, Koyama S, Asashima M, et al. Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos. Molecular and cellular biology. 1998;18(5):2867-75.

Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS biology. 2003;1(1):e10.

Leung JY, Kolligs FT, Wu R, Zhai Y, Kuick R, Hanash S, et al. Activation of AXIN2 expression by β-catenin-T cell factor: a feedback repressor pathway regulating Wnt signaling. Journal of Biological Chemistry. 2002;277(24):21657-65.

Jho E-h, Zhang T, Domon C, Joo C-K, Freund J-N, Costantini F. Wnt/β-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Molecular and cellular biology. 2002.

Jernvall J, Thesleff I. Reiterative signaling and patterning during mammalian tooth morphogenesis. Mechanisms of development. 2000;92(1):19-29.

Kondo S, Schutte BC, Richardson RJ, Bjork BC, Knight AS, Watanabe Y, et al. Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nature genetics. 2002;32(2):285-9.

Mossey P, Modell B. Epidemiology of oral clefts 2012: an international perspective. Cleft lip and palate. 2012;16:1-18.

Slayton RL, Williams L, Murray JC, Wheeler JJ, Lidral AC, Nishimura CJ. Genetic association studies of cleft lip and/or palate with hypodontia outside the cleft region. The Cleft palate-craniofacial journal. 2003;40(3):274-9.

Trybek G, Jaroń A, Gabrysz-Trybek E, Rutkowska M, Markowska A, Chmielowiec K, et al. Genetic Factors of Teeth Impaction: Polymorphic and Haplotype Variants of PAX9, MSX1, AXIN2, and IRF6 Genes. International Journal of Molecular Sciences. 2023;24(18):13889.

Pereira TV, Salzano FM, Mostowska A, Trzeciak WH, Ruiz-Linares A, Chies JA, et al. Natural selection and molecular evolution in primate PAX9 gene, a major determinant of tooth development. Proceedings of the National Academy of Sciences. 2006;103(15):5676-81.

Silvestri Jr AR, Singh I. The unresolved problem of the third molar: would people be better off without it? The Journal of the American Dental Association. 2003;134(4):450-5.

Song F, O'meara S, Wilson P, Golder S, Kleijnen J. The effectiveness and cost-effectiveness of prophylactic removal of wisdom teeth. Health Technology Assessment (Winchester, England). 2000;4(15):1-55.

Vastardis H, Karimbux N, Guthua SW, Seidman J, Seidman CE. A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nature genetics. 1996;13(4):417-21.

Xuan K, Jin F, Liu Y-L, Yuan L-T, Wen L-Y, Yang F-S, et al. Identification of a novel missense mutation of MSX1 gene in Chinese family with autosomal-dominant oligodontia. Archives of Oral Biology. 2008;53(8):773-9.

Zhang H, Hu G, Wang H, Sciavolino P, Iler N, Shen MM, et al. Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism. Molecular and cellular biology. 1997;17(5):2920-32.

Mostowska A, Biedziak B, Jagodzinski PP. Novel MSX1 mutation in a family with autosomal-dominant hypodontia of second premolars and third molars. Archives of oral biology. 2012;57(6):790-5.

Wang Y, Kong H, Mues G, D’souza R. Msx1 mutations: how do they cause tooth agenesis? Journal of dental research. 2011;90(3):311-6.

Pawlowska E, Janik-Papis K, Wisniewska-Jarosinska M, Szczepanska J, Blasiak J. Mutations in the human homeobox MSX1 gene in the congenital lack of permanent teeth. The Tohoku Journal of Experimental Medicine. 2009;217(4):307-12.

Junior BB, Echeverrigaray S. Polymorphism in the MSX1 gene in a family with upper lateral incisor agenesis. Archives of Oral Biology. 2012;57(10):1423-8.

Trybek G, Jaroń A, Grzywacz A. Association of polymorphic and haplotype variants of the MSX1 gene and the impacted teeth phenomenon. Genes. 2021;12(4):577.

Lammi L, Arte S, Somer M, Järvinen H, Lahermo P, Thesleff I, et al. Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. The American Journal of Human Genetics. 2004;74(5):1043-50.

Wilusz CJ, Wang W, Peltz SW. Curbing the nonsense: the activation and regulation of mRNA surveillance. Genes & development. 2001;15(21):2781-5.

Mao J, Wang J, Liu B, Pan W, Farr GH, Flynn C, et al. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Molecular cell. 2001;7(4):801-9.

Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, et al. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling. Nature genetics. 2000;26(2):146-7.

Callahan N, Modesto A, Meira R, Seymen F, Patir A, Vieira A. Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis. Archives of oral biology. 2009;54(1):45-9.

Vieira AR, Modesto A, Meira R, Barbosa ARS, Lidral AC, Murray JC. Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis. American Journal of Medical Genetics Part A. 2007;143(6):538-45.

ŞAHİNOĞLU Z, ARMAN ÖZÇIRPICI A. Gömülü Dişlerin Tedavi Yaklaşımları. Turkiye Klinikleri Journal of Dental Sciences. 2014;20(3).

Axenovich T, Zorkoltseva I, Aulchenko YS, Knyazev S, Kulikova A. Inheritance of hypodontia in Kerry Blue Terrier dogs. Russian Journal of Genetics. 2004;40:529-36.

Chu F, Li T, Lui V, Newsome P, Chow R, Cheung L. Prevalence of impacted teeth and associated pathologies-a radiographic study of the Hong Kong Chinese population. Hong Kong Medical Journal. 2003.

Rahman A, Alam MK, Yaacob MY, Shaari R. Radiological assessment of surgery difficulty of impacted mandibular third molar. Int Med J. 1994;21:110-2.

Peterson LJ. Principles of management of impacted teeth. Contemporary Oral and Maxillofacial Surgery, 3rd ed St Louis: Mosby. 1998:215-48.

Szubert P, Jankowski M, Krajecki M, Jankowska-Wika A, Sokalski J, editors. Analysis of predisposing factors for complications after surgical removal of mandibular wisdom teeth. Dental Forum; 2015.

ÖNEM ÖZBİLEN E. Gömülü dişlerin ortodontik tedavisi. 2022.

Bishara SE, Ortho D. Impacted maxillary canines: a review. American journal of orthodontics and dentofacial orthopedics. 1992;101(2):159-71.

Becker A. General principles related to the diagnosis and treatment of impacted teeth. Orthodontic Treatment of Impacted Teeth. 2012:1-9.

Broadbent BH. Ontogenic development of occlusion. The angle orthodontist. 1941;11(4):223-41.

Hitchin A. The impacted maxillary canine. Br Dent J. 1956;100:1-14.

Jacoby H. The etiology of maxillary canine impactions. American journal of orthodontics. 1983;84(2):125-32.

Ericson S, Kurol J. Early treatment of palatally erupting maxillary canines by extraction of the primary canines. European Journal of Orthodontics. 1988;10(4):283-95.

Brin I, Solomon Y, Zilberman Y. Trauma as a possible etiologic factor in maxillary canine impaction. American Journal of Orthodontics and Dentofacial Orthopedics: Official Publication of the American Association of Orthodontists, its Constituent Societies, and the American Board of Orthodontics. 1993;104(2):132-7.

Miller B. The influence of congenitally missing teeth on the eruption of the upper canine. Dent Pract Dent Rec. 1963;13:497-504.

TP B. Observations of the misplaced upper canine tooth. Dent Pract. 1967;18:25-33.

Becker A, SMITH P, BEHAR R. The incidence of anomalous maxillary lateral incisors in relation to palatally-displaced cuspids. The Angle Orthodontist. 1981;51(1):24-9.

Becker A, Chaushu G, Chaushu S. Analysis of failure in the treatment of impacted maxillary canines. American Journal of Orthodontics and Dentofacial Orthopedics. 2010;137(6):743-54.

Wang Y, Groppe JC, Wu J, Ogawa T, Mues G, D'Souza RN, et al. Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9. Human molecular genetics. 2009;18(15):2863-74.

Peck S, Peck L, Kataja M. The palatally displaced canine as a dental anomaly of genetic origin. The Angle Orthodontist. 1994;64(4):250-6.

Becker A, Sharabi S, Chaushu S. Maxillary tooth size variation in dentitions with palatal canine displacement. The European Journal of Orthodontics. 2002;24(3):313-8.

Neubüser A, Koseki H, Balling R. Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1. Developmental biology. 1995;170(2):701-16.

Vitria EE, Tofani I, Kusdhany L, Bachtiar EW. Genotyping analysis of the Pax9 Gene in patients with maxillary canine impaction. F1000Research. 2019;8.

Klein M, Nieminen P, Lammi L, Niebuhr E, Kreiborg S. Novel mutation of the initiation codon of PAX9 causes oligodontia. Journal of dental research. 2005;84(1):43-7.

Ahmed MK, Ye X, Taub PJ. Review of the genetic basis of jaw malformations. Journal of pediatric genetics. 2016;5(04):209-19.

Wise G, Frazier-Bowers S, D’souza R. Cellular, molecular, and genetic determinants of tooth eruption. Critical Reviews in Oral Biology & Medicine. 2002;13(4):323-35.