Cytomegalovirus (CMV) Infectıon and Intrauterine Ultrasonography Findings
Özet
Cytomegalovirus (CMV) is the most common congenital viral infection. Approximately 90% of newborns with congenital CMV infection are asymptomatic at birth. Although symptomatic newborns are particularly at risk, asymptomatic newborns are also at risk for petechiae, jaundice, hepatosplenomegaly, small for gestational age, microcephaly, and neurosensory hearing loss. Intrauterine is usually detected with fetal ultrasonography findings such as periventricular calcifications, ventriculomegaly, microcephaly, and hyperechogenic bowel and ascites. The diagnosis is usually confirmed by CMV DNA PCR from amniocentesis material after the 21st week of gestation. A more careful follow-up process can be established by carefully monitoring ultrasonography markers.
Sitomegalovirüs (CMV), en yaygın konjenital viral enfeksiyondur. Konjenital CMV enfeksiyonu olan yenidoğanların yaklaşık %90'ı doğumda asemptomatiktir. Semptomatik yenidoğanlar özellikle risk altında olsa da, asemptomatik yenidoğanlar da peteşi, sarılık, hepatosplenomegali, gebelik yaşına göre küçüklük, mikrosefali ve nörosensoriyel işitme kaybı açısından risk altındadır. İntrauterin genellikle periventriküler kalsifikasyonlar, ventrikülomegali, mikrosefali ve hiperekojen bağırsak ve asit gibi fetal ultrasonografi bulgularıyla tespit edilir. Tanı genellikle 21. gebelik haftasından sonra amniyosentez materyalinden alınan CMV DNA PCR ile doğrulanır. Ultrasonografi belirteçlerinin dikkatlice izlenmesiyle daha dikkatli bir takip süreci oluşturulabilir.
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