Sepsis
Özet
Sepsis, sistemik inflamatuvar yanıt sendromu, immün disregülasyon, mikro dolaşım bozuklukları ve uç organ fonksiyon bozukluğu ile karakterize ciddi klinik bir sendromdur. Sepsiste erken tanı ve tedavi mortalitenin azaltılmasında oldukça önemlidir. Hastanın klinik durumunun tanınması ardından en kısa sürede yeterli sıvı ve geniş spektrumlu antibiyotik tedavisine başlamak gerekmektedir. Ayrıca klinisyenler, klinik bulguların hastanın altta yatan patofizyolojisini doğru bir şekilde yansıtmayabileceğinin farkında olmalı, daha ileri monitörizasyon yöntemlerinin (ekokardiyografi, arteriyel kateter vb.) gerekebileceğini göz önünde bulundurmalıdır.
Sepsis is a serious clinical syndrome characterised by systemic inflammatory response syndrome, immune dysregulation, microcirculatory disorders and end organ dysfunction. Early diagnosis and treatment in sepsis is very important in reducing mortality. Adequate fluid and broad-spectrum antibiotic treatment should be started as soon as possible following the recognition of the patient’s clinical condition. In addition, clinicians should be aware that clinical findings may not accurately reflect the underlying pathophysiology of the patient and it should be considered that further monitoring methods (echocardiography, arterial catheter etc.) may be required.
Referanslar
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