Chlamydia Enfeksiyonları
Özet
Konakçı yelpazesi geniş olan Chlamydia türleri, hem insan hem de hayvanlarda enfeksiyona neden olan mikroorganizmalardır. Chlamydia türleri, zorunlu hücreiçi olmaları nedeniyle diğer bakterilerde olduğu gibi konvansiyonel bakteriyolojik yöntemlerle identifiye edilememektedir. Bu amaçla deney hayvanları, embriyolu tavuk yumurtaları ya da hücre kültürüne gerek duyulmaktadır. Ancak bu yöntemlerin zaman alıcı olması ve tecrübe gerektirmesi izolasyonun uzun sürmesine sebebiyet vermektedir. Bu nedenle klamidyal enfeksiyonların varlığının daha kısa sürede ortaya konması ve kesin teşhisi amacıyla serolojik ve moleküler yöntemler daha çok tercih edilmektedir. Chlamydia kaynaklı enfeksiyonların tedavisinde genellikle sistemik tedavi uygulanmaktadır. Bu amaçla tetrasiklinler daha fazla tercih alanı bulmaktadır. Ancak hastalığın eradikasyonu amacıyla kullanılan antimikrobiyal maddelerin yanında koruma ve kontrol programlarının da etkin bir şekilde uygulanması gerekmektedir.
Chlamydia species have a wide host range and are microorganisms that cause infection in both humans and animals. Chlamydia species cannot be identified by conventional bacteriological methods, as with other bacteria, because they are obligately intracellular. For this purpose, experimental animals, embryonated chicken eggs or cell culture are required. However, these methods are time consuming and require experience, causing the isolation to take a long time. For this reason, serological and molecular methods are preferred to reveal the presence of chlamydial infections in a shorter time and to make a definitive diagnosis. In the treatment of Chlamydia-related infections, systemic treatment is usually applied. Tetracyclines are more preferred for this purpose. However, in addition to antimicrobial agents used for the eradication of the disease, protection and control programs must also be implemented effectively.
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