Tıbbi Önemi Olan Eklembacaklılar

Özet

Bit, pire, tahtakurusu, sivrisinek, tatarcık, uyuz akarı, Demodex ve kene gibi ektoparazitler hem hastalık vektörü hem de doğrudan morbidite nedeni olarak insan sağlığında önemli rol oynarlar. Vücut biti (Pediculus humanus humanus) pediküloz ile ilişkilidir ve endemik tifüs, siper ateşi ve tekrarlayan ateşi bulaştırabilirler. Pireler, özellikle Xenopsylla cheopis, veba ve fare tifüsünü yaymakla ünlüdür. Tahtakuruları (Cimex türleri), kanıtlanmış bir hastalık vektörü olmamakla birlikte alerjik reaksiyonlara, psikolojik strese ve cilt tahrişine neden olurlar. Anopheles, Aedes ve Culex cinslerine ait sivrisinekler, sıtma, dang humması ve Batı Nil virüsü gibi yaşamı tehdit eden hastalıkları bulaştırırlar. Kum sinekleri (Phlebotomus ve Lutzomyia türleri) leişmanyaz ve tatarcık ateşi virüslerinin vektörüdür. Sarcoptes scabiei gibi akarlar, yoğun kaşıntı ve ikincil enfeksiyonlarla karakterize uyuz hastalığına neden olurken, Demodex akarları bazı bireylerde rosacea ve blefarit gibi rahatsızlıklara katkıda bulunur. Sert keneler (Ixodidae), Lyme hastalığı, babezyoz ve kene kaynaklı ensefalitin ve yumusak keneler ise (Argasidae), kene-kaynaklı tekrarlayan ateşin başlıca vektörleridir. Tüm bu ektoparazitler, doğrudan parazitlik ve hastalık bulaşması yoluyla halk sağlığını önemli ölçüde etkilerler. Surveyans, kontrol ve ilişkili hastalıkların önlenmesi için sağlam stratejiler gerekmektedir.

Referanslar

Barros JM, Dias CR. Pediculosis pubis: Clinical presentation, diagnosis, and management. Dermatology Online Journal. 2019;25(4): 1-5.

Batır MB, Yasin Y, Jaiswal A, Tabak T, Kurt Ö. First report of the gene mutations associated with permethrin resistance in head lice (Pediculus humanus capitis De Geer, 1767) from primary school children in Istanbul (Türkiye) and Nagarkot (Nepal). Pathogens. 2024;13(12): 1116.

Fu YT, Yao C, Deng YP, Elsheikha HM, Shao R, Zhu XQ, Liu GH. Human pediculosis, a global public health problem. Infectious Diseases of Poverty. 2022;11(1): 58.

Lavoipierre M, Cumming S. A global perspective on pediculosis pubis. Epidemiology and Infection. 2018:146(7): 839-848.

Mumcuoğlu KY, Taylan Özkan A. 28. Bölüm: Bit Enfestasyonları. In: Tıbbi Parazitoloji ve Pratik Uygulamaları. Eroğlu F, Çetinkaya Ü (eds.). Efe Akademik Yayıncılık. 2024, p. 167-172.

Mumcuoglu KY, Pollack RJ, Reed DL, Barker SC, Gordon S, Toloza AC, et al. International recommendations for an effective control of head louse infestations. International Journal of Dermatology. 2021;60(3): 272-280.

Sensoz S, Bilgener E, Mumcuoglu KY, Taylan-Ozkan A. Pediculicide regulations and usage trends in Türkiye in 2015-2022. International Journal of Dermatology. 2024;63(3): 359-367. https://doi.org/10.1111/ijd.17001.

Walker DH, McGinnis LM. Lice: The biology and management of head, body, and pubic lice. Clinical Infectious Diseases. 2020;67(1): 121-126.

Bitam I, Dittmar K, Parola P, Whiting MF, Raoult D. Fleas and flea-borne diseases. International Journal of Infectious Diseases. 2010; 14(8): e667-76.

Feingold BF, Benjamini E, Michaeli D. The allergic responses to insect bites. Annual Review of Entomology. 1968;13(1): 137-158.

İnci A, Doğanay M, Özdarendeli A, Düzlü Ö, Yıldırım A. Overview of zoonotic diseases in Turkey: The one health concept and future threats. Türkiye Parazitolojii Dergisi. 2018;42(1): 39.

Keskin A, Hastriter MW, Beaucournu JC. Fleas (Siphonaptera) of Turkey: species composition, geographical distribution and host associations. Zootaxa, 2018;4420(2): 211-228.

Rust MK, Dryden MW. The biology, ecology, and management of the cat flea. Annual Review of Entomology, 1997;42: 451-473.

Doggett SL, Lee CY. Historical and contemporary control options against bed bugs, Cimex spp. Annual Review of Entomology. 2023;68: 169-190.

Doggett SL, Miller DM, Lee CY (|Eds.) Advances in the Biology and Management of Modern Bed Bugs. John Wiley & Sons; 2018.

Doggett SL, Dwyer DE, Peñas PF, Russell RC. Bed bugs: clinical relevance and control options. Clinical Microbiology Reviews. 2012;25(1): 164-192.

Dursun A, Fent M. First record of Cimex lectularius Linnaeus, 1758 (Cimicidae: Heteroptera) for Amasya. Journal of the Heteroptera of Turkey. 2024;6: 35-38.

Goddard J, Deshazo R. Bed bugs (Cimex lectularius) and clinical consequences of their bites. JAMA 2009;301: 1358-1366.

Lee CY, Wang C, Su NY. Perspective on biology and management of bed bugs: introduction. Journal of Economic Entomology. 2023;116(1): 1-4.

Leung AK, Lam JM, Barankin B, Leong KF, Hon KL. Bed bug infestation: An updated review. Current Pediatric Reviews. 2024;20(2): 137-149.

Palenchar DJ, Gellatly KJ, Yoon KS, Mumcuoglu KY, Shalom U, Clark JM. Quantitative sequencing for the determination of kdr-type resistance allele (V419L, L925I, I936F) frequencies in common bed bug (Hemiptera: Cimicidae) populations collected from Israel. Journal of Medical Entomology. 2015;52(5): 1018-1027.

Ruh E, Taylan Özkan A. Parazitlerden kaynaklanan salgınlar: Dünyadan ve Türkiye’den örnekler. Mikrobiyoloji Bulteni. 2023;57(2): 317-329. https://doi.org/10.5578/mb.20239926.

Balcıoğlu IC, Ecemiş T, Ayer A, Özbel Y. Subungual myiasis in a woman with psychiatric disturbance. Parasitology International. 2008;57(4): 509-511.

Mumcuoglu KY. Human Lice, Bed Bugs, Sand Flies, Myiasis, and Leeches. In: Manson’s Tropical Diseases. Farrar J, Hotez PJ, Junghanss T, Kang G, Lalloo D, White NJ, Garcia PJ. (Eds.), 24th. Edition, Elsevier, 2023. pp. 840-853.

Singh A, Singh Z. Incidence of myiasis among humans-a review. Parasitology Research. 2015;114(9): 3183-3199. doi: 10.1007/s00436-015-4620-y.

Taylan-Ozkan A, Babur C, Kilic S, Nalbantoglu S, Dalkilic I, Mumcuoglu KY. Urinogenital myiasis caused by Psychoda albipennis (Diptera: Nematocera) in Turkey. Int J Dermatol. 2004;43: 904-905.

Uzun L, Cinar F, Beder LB, Aslan T, Altintas K. Radial mastoidectomy cavity myiasis caused by Wohlfahrtia magnifica. Journal of Laryngology and Otology. 2004;118: 54-56.

Zumpt F. Myiasis in Man and Animals in the Old World. Butterworth-Heinemann; 1965.

Alten SB, Caglar SS, Ozer N. Malaria and its vectors in Turkey. European Mosquito Bulletin 2000;7: 27-33.

Dahmana H, Mediannikov O. Mosquito-borne diseases emergence/resurgence and how to effectively control it biologically. Pathogens. 2020;9(4): 310.

Demirci B, Bedir H, Öztürk M, Akiner MM. Status of the invasive mosquito species Aedes aegypti (L., 1762) and Aedes albopictus (Skuse, 1895) (Diptera: Culicidae) in Turkey. Turkish Journal of Entomology. 2021;45(2): 279-292.

Ergunay K, Gunay F, Erisoz Kasap O, Oter K, Gargari S, Karaoglu T, et al. . Serological, molecular and entomological surveillance demonstrates widespread circulation of West Nile virus in Turkey. PLoS Neglected Tropical Diseases. 2014;8(7): e3028.

Fostini AC, Golpanian RS, Rosen JD, Xue RD, Yosipovitch G. Beat the bite: pathophysiology and management of itch in mosquito bites. Itch. 2019;4(1): 19. doi: 10.1097/itx.0000000000000019 30.

Heilesen B. Studies on mosquito bites. Acta Allergologica. 1949;2(3): 245–267. doi: 10.1111/j.1398-9995.1949.tb03310.x.

Mellanby K. Man’s reaction to mosquito bites. Nature. 1946;158: 554. doi: 10.1038/158554c0.

Peng Z, Yang M, Simons FER. Immunologic mechanisms in mosquito allergy: correlation of skin reactions with specific IgE and IgG antibodies and lymphocyte proliferation response to mosquito antigens. Annals of Allergy, Asthma & Immunology, 1996;77(3): 238-244.

Simons FE, Peng Z. Skeeter syndrome. Journal of Allergy and Clinical Immunology. 1999;104(3): 705-707. doi: 10.1016/s0091-6749(99)70348-9.

Vander Does A, Labib A, Yosipovitch G. Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment. Frontiers in Immunology. 2022;13: 1024559.

Zhou YH, Zhang ZW, Fu YF, Zhang GC, Yuan S. Carbon dioxide, odorants, heat and visible cues affect wild mosquito landing in open spaces. Frontiers in Behavioral Neuroscience. 2018;12: 86. doi: 10.3389/fnbeh.2018.00086.

Abdeladhim M, Kamhawi S, Valenzuela JG. What’s behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity. Infection, Genetics and Evolution. 2014;28: 691-703.

Alkan C, Erisoz Kasap O, Alten B, de Lamballerie X, Charrel RN. Sandfly-borne phlebovirus isolations from Turkey: new insight into the sandfly fever Sicilian and sandfly fever Naples species. PLoS Neglected Tropical Diseases. 2016;10(3): e0004519.

Çarhan A, Uyar Y, Özkaya E, Ertek M, Dobler G, Dilcher M, et al. Characterization of a sandfly fever Sicilian virus isolated during a sandfly fever epidemic in Turkey. Journal of Clinical Virology. 2010;48(4): 264-269.

Ergünay K, Polat C, Özkul A. Vector-borne viruses in Turkey: a systematic review and bibliography. Antiviral Research. 2020;183: 104934.

Theodos CM, Titus RG. Salivary gland material from the sand fly Lutzomyia longipalpis has an inhibitory effect on macrophage function in vitro. Parasite Immunology. 1993;15(8): 481-487.

Touray M, Bakirci S, Ulug D, Gulsen SH, Cimen H, Yavasoglu SI, et al. Arthropod vectors of disease agents: their role in public and veterinary health in Turkiye and their control measures. Acta Tropica. 2023;243: 106893.

Bilò MB, Danieli MG, Moroncini G, Martini M. Hymenoptera venom allergy and anaphylaxis. Current Pharmaceutical Design. 2023;29(3): 165-177.

Golden DB. Insect sting allergy and venom immunotherapy: a model and a mystery. Journal of Allergy and Clinical Immunology. 2005;115(3): 439-447.

Pasaoglu G, Sin BA, Misirligil Z. Rush hymenoptera venom immunotherapy is efficacious and safe. Journal of Investigational Allergology and Clinical Immunology. 2006;16(4): 232.

Canıtez Y. Arı alerjisi. KlinikTıp Pediatri Dergisi. 2017;9: 109-116.

Kalyoncu AF, Demir AU, Özcan Ü, Özkuyumcu C, Şahin AA, Bariş YI. Bee and wasp venom allergy in Turkey. Annals of Allergy Asthma and Immunology. 1997;78: 408-412.

Brenner RJ, Kramer RD. Cockroaches (Blattaria). In: Medical and Veterinary Entomology, Chapter 6, 2019. pp. 61-77.

Nasirian H. Infestation of cockroaches (Insecta: Blattaria) in the human dwelling environments: a systematic review and meta-analysis. Acta Tropica. 2017;167: 86-98.

O'Rourke FJ. The medical and veterinary importance of the Formicidae. Insectes Sociaux. 1956;3: 107-118.

Blum MS. Ant venoms: chemical and pharmacological properties. Journal of Toxicology: Toxin Reviews. 1992;11(2): 115-164.

Duran S, Yürekli A. Quality of life and satisfaction with life in patients with skin diseases. Psychology Health and Medicine. 2023;28(10): 2848-2859.

Uzun S, Durdu M, Yürekli A, Mülayim MK, Akyol M, et al. Clinical practice guidelines for the diagnosis and treatment of scabies. International Journal of Dermatology. 2024;63(12): 1642-1656.

Yürekli A. Is there a really resistance to scabies treatment with permethrin? In vitro killing activity of permethrin on Sarcoptes scabiei from patients with resistant scabies. Dermatologic Therapy. 2022;35(3): e15260.

Yürekli A. A new sign with UV dermoscope in the diagnosis of scabies: Ball sign. Skin Research and Technology. 2023;29(5): e13336.

Yürekli A, Muslu İ, Pektaş SD, Alataş ET, Aydoğdu CT, Daşgin D. Using ultraviolet dermoscopy in diagnosing scabies. Experimental Dermatology. 2023;32(11): 1996-1999.

Yürekli A, Can İ, Oğuz M. Using ultraviolet light in diagnosing scabies: Scabies' sign via Wood's lamp. Journal of the American Academy of Dermatology. 2023;89(5): e195-e196.

Bitton E, Aumond S. Demodex and eye disease: a review. Clinical and Experimental Optometry. 2021;104(3): 285-294.

Yürekli A, Aytekin S. Demodikozis. Kartal SP, editör. Dermatoloji - Güncel. 1. Baskı. Ankara: Türkiye Klinikleri; 2023. pp.78-81.

Yurekli A, Botsali A. The comparative in vitro killing activity of tea tree oil versus permethrin on Demodex folliculorum of rosacea patients. Journal of Cosmetic Dermatology. 2022;21(5): 2268-2272.

Akdemir C, Karaman Ü, Güler NC, Direkel Ş, Uzunoğlu E, Şentürk H, Ayhan U. Prevalence of house dust mites and presence of Der p 1 and Der f 1 in Ordu, Giresun, Trabzon and Rize provinces. Prevalence. 2023;47(3): 179-183.

Arlian LG, Morgan MS. A review of house dust mite allergens. Allergy and Clinical Immunology International, 2019;31(1): 1-12.

Aykut M, Erman ÖK, Doğan S. Seasonal changes of house dust mite population in Bitlis and Muş provinces of Turkey. Türkiye Parazitoloji Dergisi. 2013;37(2): 113-117.

Colloff MJ. Dust mites. CSIRO Publishing, Collingwood, Australia. 2009.

Devi AK, Anggraeni S. Atopic dermatitis due to house dust mite: A review. International Journal of Research Publications, 2023;117(1): 15.

Gülbahar O, Mete N, Kokuludağ A, Sin AZ, Sebik F. House dust mite allergens in Turkish homes. Allergy. 2004; 59(2): 231-241.

Mumcuoğlu KY, Özkan AT. Preventive measures to avoid contact with house dust mites and their allergens. Acarological Studies. 2020;2(1): 1-6.

Platts-Mills TAE, de Weck AL. Dust mite allergens and asthma: review and future directions. Journal of Allergy and Immunology. 2021;45(4): 350-360.

Thomas WR. House dust mite allergens: biology and role in allergic diseases. Clinical Reviews in Allergy & Immunology, 2020;59(2): 110-130.

Acici M, Demirtaş S, Gürler AT, Bölükbaş CS, Şinasi UM. A diagnostic survey of chigger mites (Acari: Trombiculidae) of wild rodents and soricomorphs in Turkey. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2021;27(1).

Mumcuoglu KY, Keskin A, Aykut M, Zeytun E, Taylan Ozkan A. Tıbbi Önemi Olan Akarlar. Chapter 10. In: Genel Akaroloji. Dogan S, Ozman-Sullivan SK (eds.). Nobel Akademik Kitabevi, Turkey. 2023. pp. 243-280.

Akdemir C, Gülcan E, Tanritanir P. Case report: Dermanyssus gallinae in a patient with pruritus and skin lesions. Türkiye Parazitoloji Dergisi. 2009;;33(3): 242-244.

Doğan S. An overview of research on the family Cheyletidae (Acariformes) in Turkey, with a checklist of the Turkish cheyletid mites. Systematic and Applied Acarology. 2022;27(6): 1132-1151.

Emre S, Yagli S, Metin A, Kiliçarslan A, Pektas SD. Şeyletiella dermatiti. Turkish Archives of Dermatology and Venereology. 2011;45(4): 213.

Bursali A, Keskin A, Tekin S. A review of the ticks (Acari: Ixodida) of Turkey: species diversity, hosts and geographical distribution. Experimental and Applied Acarology. 2012;57: 91-104.

Bakırcı S, Aysul N, Bilgiç HB, Hacılarlıoğlu S, Eren H, Karagenç T. Tick bites on humans in southwestern region of Turkey: species diversity. Türkiye Parazitoloji Dergisi. 2019;43(1): 30-35.

Guglielmone AA, Robbins RG, Apanaskevich DA, Petney TN, Estrada-Peña A, Horak IG. The Hard Ticks of the World. Springer, Dordrecht. 2014.

Inci A, Yildirim A, Duzlu O, Doganay M, Aksoy S. Tick-borne diseases in Turkey: A review based on one health perspective. PLoS Neglected Tropical Diseases. 2016;10(12): e0005021.

Kar S, Yilmazer N, Akyildiz G, Gargili A. The human infesting ticks in the city of Istanbul and its vicinity with reference to a new species for Turkey. Systematic and Applied Acarology. 2017;22(12): 2245-2255.

Karaer Z, Guven E, Nalbantoglu S, Kar S, Orkun O, Ekdal K, Kocak A, Akcay A. Ticks on humans in Ankara, Turkey. Experimental and Applied Acarology. 2011;54: 85-91.

Karasartova D, Gureser AS, Gokce T, Celebi B, Yapar D, Keskin A, et al. Bacterial and protozoal pathogens found in ticks collected from humans in Corum province of Turkey. PLoS Neglected Tropical Diseases. 2018;12(4): e0006395.

Keskin A, Keskin A, Bursali A, Tekin S. Ticks (Acari: Ixodida) parasitizing humans in Corum and Yozgat provinces, Turkey. Experimental and Applied Acarology. 2015;67: 607-616.

Touray M, Bakirci S, Ulug D, Gulsen SH, Cimen H, Yavasoglu SI, et al. Arthropod vectors of disease agents: their role in public and veterinary health in Türkiye and their control measures. Acta Tropica. 2023;243:106893.

Yayınlanan

7 Mart 2025

Lisans

Lisans