Paramiksovirüsler

Özet

Paramiksovirüsler respiratuar sinsityal virüs ve insan metapnömovirüsü, parainfluenza, kızamık virüsü, kabakulak virüsü, Hendra ve Nipah virüsleri (zoonotik ensefalitler) içeren geniş bir ailedir. Negatif polariteli, segmente olmayan genoma sahip zarflı RNA virüsleridir. Hepsi antijenik olarak stabildir. Temas veya büyük damlacıklar yoluyla bulaşırlar ve enfeksiyonları solunum yolu bulguları ile başlar. Tüm viral replikasyon döngüleri hücrelerin sitoplazmasında gerçekleşir. Viral RNA veya viral antijenlerin saptanması ile tanı konur. Parainfluenza ve insan metapnömovirüsleri için aşı mevcut değildir. Hem kızamık hem de kabakulak için etkili aşılar mevcuttur. Hendra ve Nipah virüsleri zoonotik paramiksovirüsleridir; yüksek ölüm oranına sahip ensefalite neden olurlar.

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7 Mart 2025

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