Pelvik Fraktür İle İlişkili Hemoraji Yönetimi

Özet

Pelvis kırıkları yüksek enerjili travmalar sonrası oluşur ve genellikle çoklu sistem yaralanmaların bir komponentidir. Bu kırıklar mortal seyredebilir. Erken dönem ölümlerin en sık nedeni ise kanamalardır. Pelvis kırıklarını tanıma da fizik muayene ve görüntüleme yöntemleri önemlidir ve kırığa ait sınıflamalar geliştirilmiştir. Ancak kanamayı belirlemede genellikle nicel veriler yoktur ve bu sınıflamalar yetersizdir. Pelvis kırıklarına bağlı kanamalar büyük ölçüde venöz sisteme ait yapılardan kaynaklansa da arteriyel kanamalarda olabilir. Hastanın ilk değerlendirmesiyle hemodinamik stabilite belirlenir ve tedavi protokolü kanamaya göre değişir. Kırık tedavisinde primer rol ortopedistler de olsa da kanama ve hasta yaşamı söz konusu olduğunda bu hastalara multidisipliner yaklaşmak gereklidir. Yakın takip için uygun yoğun bakım şartları, acil ameliyathane odaları pelvis kırıklarına bağlı kanama yönetiminde şarttır. Kanama tedavisinde basit pelvik çarşaf uygulamalarından, anjio-embolizasyona kadar birçok yöntem bulunmaktadır. Kırık tedavisi gibi pelvis kırığına bağlı kanamaların tedavisi de zordur. Bu nedenle deneyimli merkezler ve altyapısı sağlam hastanelerde bu hastalar değerlendirilmelidir.

Pelvic fractures occur after high-energy trauma and are usually a component of multi-system injuries. These fractures may have a mortal progression. The most common cause of early death is haemorrhage. Physical examination and imaging methods are important in the recognition of pelvic fractures and fracture classifications have been developed. However, there is usually no quantitative data in determining bleeding and these classifications are insufficient. Although haemorrhage due to pelvic fractures is mostly caused by venous structures, arterial haemorrhage may also occur. Haemodynamic stability is determined by the initial assessment of the patient and the treatment protocol varies according to the bleeding. Even though orthopaedists have the primary role in the treatment of fractures, a multidisciplinary approach to these patients is necessary when bleeding and patient survival are in doubt. Appropriate intensive care conditions for close follow-up and emergency operating theatre rooms are essential in the management of bleeding due to pelvic fractures. There are many methods for the treatment of bleeding, ranging from simple pelvic sheet applications to angioembolisation. Like fracture treatment, treatment of bleeding due to pelvic fracture is also difficult. Therefore, these patients should be evaluated in experienced centers and hospitals with good infrastructure.

Referanslar

Ramser M, Vach W, Strub N, Cadosch D, Saxer F, Eckardt H. Theimpact of specific fracture characteristics of low-energy fractures of the pelvis on mortality. BMC Geriatr. 2022 Aug 15;22(1):669. doi: 10.1186/s12877-022-03223-z.

Rankin IA, Webster CE, Gibb I, Clasper JC, Masouros SD. Pelvic injury patterns in blast: Morbidity and mortality. J Trauma Acute Care Surg. 2020 Jun;88(6):832-838. doi: 10.1097/TA.0000000000002659.

Vaidya R, Scott AN, Tonnos F, Hudson I, Martin AJ, Sethi A. Patients with pelvic fractures from blunt trauma. What is the cause of mortality and when? Am J Surg. 2016 Mar;211(3):495-500. doi: 10.1016/j.amjsurg.2015.08.038.

Tile M. AcutePelvicFractures: I. Causation and Classification. J Am Acad Orthop Surg. 1996 May;4(3):143-151. doi: 10.5435/00124635-199605000-00004.

Young JW, Burgess AR, Brumback RJ, Poka A. Pelvic fractures: value of plain radiography in early assessment and management. Radiology. 1986 Aug;160(2):445-51. doi: 10.1148/radiology.160.2.3726125.

Langford JR, Burgess AR, Liporace FA, Haidukewych GJ. Pelvic fractures: part 1. Evaluation, classification, andresuscitation. J Am Acad Orthop Surg. 2013 Aug;21(8):448-57. doi: 10.5435/JAAOS-21-08-448.

Hallinan JT, Tan CH, Pua U. Emergency computed tomography for acute pelvic trauma: where is the bleeder? Clin Radiol. 2014 May;69(5):529-37. doi: 10.1016/j.crad.2013.12.016.

Ding HM, Yin ZX, Zhou XB, Li YB, Tang ML, Chen SH, Xu DC, Zhong SZ. Three-dimensional visualization of pelvic vascularity. Surg Radiol Anat. 2008 Jul;30(5):437-42. doi: 10.1007/s00276-008-0348-z.

Abboud AE, Boudabbous S, Andereggen E, de Foy M, Ansorge A, Gamulin A. Incidence rate and topography of intra-pelvic arterial lesions associated with high-energy blunt pelvic ring injuries: a retrospective cohort study. BMC Emerg Med. 2021 Jun 30;21(1):75. doi: 10.1186/s12873-021-00470-y.

Geeraerts T, Chhor V, Cheisson G, Martin L, Bessoud B, Ozanne A, Duranteau J. Clinical review: initial management of blunt pelvic trauma patients with haemodynamic instability. Crit Care. 2007;11(1):204. doi: 10.1186/cc5157.

Baqué P, Trojani C, Delotte J, Séjor E, Senni-Buratti M, de Baqué F, Bourgeon A. Anatomical consequences of "open-book" pelvic ring disruption: a cadaver experimental study. Surg Radiol Anat. 2005 Dec;27(6):487-90. doi: 10.1007/s00276-005-0027-2.

Stover MD, Edelstein AI, Matta JM. Chronic Anterior Pelvic Instability: Diagnosis and Management. J Am Acad Orthop Surg. 2017 Jul;25(7):509-517. doi: 10.5435/JAAOS-D-15-00338.

Mauffrey C, Cuellar DO 3rd, Pieracci F, Hak DJ, Hammerberg EM, Stahel PF, Burlew CC, Moore EE. Strategies for the management of haemorrhage following pelvic fractures and associated trauma-induced coagulopathy. Bone Joint J. 2014 Sep;96-B(9):1143-54. doi: 10.1302/0301-620X.96B9.33914.

Dickinson K, Roberts I. Medical anti-shock trousers (pneumatic anti-shock garments) for circulatory support in patients with trauma. Cochrane Database Syst Rev. 2000;1999(2):CD001856. doi: 10.1002/14651858.CD001856.

Cayten CG, Berendt BM, Byrne DW, Murphy JG, Moy FH. A study of pneumatic antishock garments in severely hypotensive trauma patients. J Trauma. 1993 May;34(5):728-33; discussion 733-5. doi: 10.1097/00005373-199305000-00016.

Fu CY, Wu YT, Liao CH, Kang SC, Wang SY, Hsu YP, Lin BC, Yuan KC, Kuo IM, Ouyang CH. Pelvic circumferential compression devices benefit patients with pelvic fractures who need transfers. Am J Emerg Med. 2013 Oct;31(10):1432-6. doi: 10.1016/j.ajem.2013.06.044.

Prasarn ML, Conrad B, Small J, Horodyski M, Rechtine GR. Comparison of circumferential pelvic sheeting versus the T-POD on unstable pelvic injuries: A cadaveric study of stability. Injury. 2013 Dec;44(12):1756-9. doi: 10.1016/j.injury.2013.05.016.

Prasarn ML, Horodyski M, Conrad B, Rubery PT, Dubose D, Small J, Rechtine GR. Comparison of external fixation versus the trauma pelvic orthotic device on unstable pelvic injuries: a cadaveric study of stability. J Trauma Acute Care Surg. 2012 Jun;72(6):1671-5. doi: 10.1097/TA.0b013e31824526a7.

Lee C, Sciadini M. TheUse of External Fixation for the Management of the Unstable Anterior Pelvic Ring. J Orthop Trauma. 2018 Sep;32 Suppl6:S14-S17. doi: 10.1097/BOT.0000000000001251.

Scaglione M, Parchi P, Digrandi G, Latessa M, Guido G. External fixation in pelvic fractures. Musculoskelet Surg. 2010 Nov;94(2):63-70. doi: 10.1007/s12306-010-0084-5. Epub 2010 Nov 18.

Hu SB, Xu H, Guo HB, Sun T, Wang CJ. External fixation in early treatment of unstable pelvic fractures. Chin Med J (Engl). 2012 Apr;125(8):1420-4.

Schmal H, Larsen MS, Stuby F, Strohm PC, Reising K, Goodwin Burri K. Effectiveness and complications of primary C-clamp stabilization or external fixation for unstable pelvic fractures. Injury. 2019 Nov;50(11):1959-1965. doi: 10.1016/j.injury.2019.08.039.

Gewiess J, Luedi MM, Schnüriger B, Tosounidis TH, Keel MJB, Bastian JD. Effect of C-Clamp Application on Hemodynamic Instability in Polytrauma Victims with Pelvic Fracture. Medicina (Kaunas). 2022 Sep 16;58(9):1291. doi: 10.3390/medicina58091291.

Abrassart S, Stern R, Peter R. Unstable pelvic ring injury with hemodynamic instability: what seems the best procedure choice and sequence in the initial management? Orthop Traumatol Surg Res. 2013 Apr;99(2):175-82. doi: 10.1016/j.otsr.2012.12.014.

Benders KEM, Leenen LPH. Management of Hemodynamically Unstable Pelvic Ring Fractures. Front Surg. 2020 Dec4;7:601321. doi: 10.3389/fsurg.2020.601321.

Vaidya R, Waldron J, Scott A, Nasr K. Angiography and Embolization in the Management of Bleeding Pelvic Fractures. J Am Acad Orthop Surg. 2018 Feb 15;26(4):e68-e76. doi: 10.5435/JAAOS-D-16-00600.

Marzi I, Lustenberger T. Management of Bleeding Pelvic Fractures. Scand J Surg. 2014 Jun;103(2):104-111. doi: 10.1177/1457496914525604.

Suzuki T, Smith WR, Moore EE. Pelvic packing or angiography: competitive or complementary? Injury. 2009 Apr;40(4):343-53. doi: 10.1016/j.injury.2008.12.006.

Burlew CC. Preperitoneal pelvic packing for exsanguinating pelvic fractures. IntOrthop. 2017 Sep;41(9):1825-1829. doi: 10.1007/s00264-017-3485-3.

Moskowitz EE, Burlew CC, Moore EE, Pieracci FM, Fox CJ, Campion EM, Lawless RA, Cohen MJ. Preperitoneal pelvic packing is effective for hemorrhage control in open pelvic fractures. Am J Surg. 2018 Apr;215(4):675-677. doi: 10.1016/j.amjsurg.2017.

Martinez B, Breeding T, Katz J, Patel H, Santos RG, Elkbuli A. Outcomes of Preperitoneal Packing and Angioembolization for Hemorrhage Control in Hemodynamically Unstable Pelvic Fractures: A Systematic Review and Meta-Analysis. AmSurg. 2024 Mar;90(3):455-464. doi: 10.1177/00031348231216488.

McDonogh JM, Lewis DP, Tarrant SM, Balogh ZJ. Preperitoneal packing versus angioembolization for the initial management of hemodynamically unstable pelvic fracture: A systematic review and meta-analysis. J Trauma Acute Care Surg. 2022 May 1;92(5):931-939. doi: 10.1097/TA.0000000000003528.

Bosch U, Pohlemann T, Tscherne H. Strategiebei der Primär vers or gung von Beckenverletzungen [Primarymanagement of pelvicinjuries]. Orthopade. 1992 Nov;21(6):385-92. German. PMID: 1475124.

Referanslar

Ramser M, Vach W, Strub N, Cadosch D, Saxer F, Eckardt H. Theimpact of specific fracture characteristics of low-energy fractures of the pelvis on mortality. BMC Geriatr. 2022 Aug 15;22(1):669. doi: 10.1186/s12877-022-03223-z.

Rankin IA, Webster CE, Gibb I, Clasper JC, Masouros SD. Pelvic injury patterns in blast: Morbidity and mortality. J Trauma Acute Care Surg. 2020 Jun;88(6):832-838. doi: 10.1097/TA.0000000000002659.

Vaidya R, Scott AN, Tonnos F, Hudson I, Martin AJ, Sethi A. Patients with pelvic fractures from blunt trauma. What is the cause of mortality and when? Am J Surg. 2016 Mar;211(3):495-500. doi: 10.1016/j.amjsurg.2015.08.038.

Tile M. AcutePelvicFractures: I. Causation and Classification. J Am Acad Orthop Surg. 1996 May;4(3):143-151. doi: 10.5435/00124635-199605000-00004.

Young JW, Burgess AR, Brumback RJ, Poka A. Pelvic fractures: value of plain radiography in early assessment and management. Radiology. 1986 Aug;160(2):445-51. doi: 10.1148/radiology.160.2.3726125.

Langford JR, Burgess AR, Liporace FA, Haidukewych GJ. Pelvic fractures: part 1. Evaluation, classification, andresuscitation. J Am Acad Orthop Surg. 2013 Aug;21(8):448-57. doi: 10.5435/JAAOS-21-08-448.

Hallinan JT, Tan CH, Pua U. Emergency computed tomography for acute pelvic trauma: where is the bleeder? Clin Radiol. 2014 May;69(5):529-37. doi: 10.1016/j.crad.2013.12.016.

Ding HM, Yin ZX, Zhou XB, Li YB, Tang ML, Chen SH, Xu DC, Zhong SZ. Three-dimensional visualization of pelvic vascularity. Surg Radiol Anat. 2008 Jul;30(5):437-42. doi: 10.1007/s00276-008-0348-z.

Abboud AE, Boudabbous S, Andereggen E, de Foy M, Ansorge A, Gamulin A. Incidence rate and topography of intra-pelvic arterial lesions associated with high-energy blunt pelvic ring injuries: a retrospective cohort study. BMC Emerg Med. 2021 Jun 30;21(1):75. doi: 10.1186/s12873-021-00470-y.

Geeraerts T, Chhor V, Cheisson G, Martin L, Bessoud B, Ozanne A, Duranteau J. Clinical review: initial management of blunt pelvic trauma patients with haemodynamic instability. Crit Care. 2007;11(1):204. doi: 10.1186/cc5157.

Baqué P, Trojani C, Delotte J, Séjor E, Senni-Buratti M, de Baqué F, Bourgeon A. Anatomical consequences of "open-book" pelvic ring disruption: a cadaver experimental study. Surg Radiol Anat. 2005 Dec;27(6):487-90. doi: 10.1007/s00276-005-0027-2.

Stover MD, Edelstein AI, Matta JM. Chronic Anterior Pelvic Instability: Diagnosis and Management. J Am Acad Orthop Surg. 2017 Jul;25(7):509-517. doi: 10.5435/JAAOS-D-15-00338.

Mauffrey C, Cuellar DO 3rd, Pieracci F, Hak DJ, Hammerberg EM, Stahel PF, Burlew CC, Moore EE. Strategies for the management of haemorrhage following pelvic fractures and associated trauma-induced coagulopathy. Bone Joint J. 2014 Sep;96-B(9):1143-54. doi: 10.1302/0301-620X.96B9.33914.

Dickinson K, Roberts I. Medical anti-shock trousers (pneumatic anti-shock garments) for circulatory support in patients with trauma. Cochrane Database Syst Rev. 2000;1999(2):CD001856. doi: 10.1002/14651858.CD001856.

Cayten CG, Berendt BM, Byrne DW, Murphy JG, Moy FH. A study of pneumatic antishock garments in severely hypotensive trauma patients. J Trauma. 1993 May;34(5):728-33; discussion 733-5. doi: 10.1097/00005373-199305000-00016.

Fu CY, Wu YT, Liao CH, Kang SC, Wang SY, Hsu YP, Lin BC, Yuan KC, Kuo IM, Ouyang CH. Pelvic circumferential compression devices benefit patients with pelvic fractures who need transfers. Am J Emerg Med. 2013 Oct;31(10):1432-6. doi: 10.1016/j.ajem.2013.06.044.

Prasarn ML, Conrad B, Small J, Horodyski M, Rechtine GR. Comparison of circumferential pelvic sheeting versus the T-POD on unstable pelvic injuries: A cadaveric study of stability. Injury. 2013 Dec;44(12):1756-9. doi: 10.1016/j.injury.2013.05.016.

Prasarn ML, Horodyski M, Conrad B, Rubery PT, Dubose D, Small J, Rechtine GR. Comparison of external fixation versus the trauma pelvic orthotic device on unstable pelvic injuries: a cadaveric study of stability. J Trauma Acute Care Surg. 2012 Jun;72(6):1671-5. doi: 10.1097/TA.0b013e31824526a7.

Lee C, Sciadini M. TheUse of External Fixation for the Management of the Unstable Anterior Pelvic Ring. J Orthop Trauma. 2018 Sep;32 Suppl6:S14-S17. doi: 10.1097/BOT.0000000000001251.

Scaglione M, Parchi P, Digrandi G, Latessa M, Guido G. External fixation in pelvic fractures. Musculoskelet Surg. 2010 Nov;94(2):63-70. doi: 10.1007/s12306-010-0084-5. Epub 2010 Nov 18.

Hu SB, Xu H, Guo HB, Sun T, Wang CJ. External fixation in early treatment of unstable pelvic fractures. Chin Med J (Engl). 2012 Apr;125(8):1420-4.

Schmal H, Larsen MS, Stuby F, Strohm PC, Reising K, Goodwin Burri K. Effectiveness and complications of primary C-clamp stabilization or external fixation for unstable pelvic fractures. Injury. 2019 Nov;50(11):1959-1965. doi: 10.1016/j.injury.2019.08.039.

Gewiess J, Luedi MM, Schnüriger B, Tosounidis TH, Keel MJB, Bastian JD. Effect of C-Clamp Application on Hemodynamic Instability in Polytrauma Victims with Pelvic Fracture. Medicina (Kaunas). 2022 Sep 16;58(9):1291. doi: 10.3390/medicina58091291.

Abrassart S, Stern R, Peter R. Unstable pelvic ring injury with hemodynamic instability: what seems the best procedure choice and sequence in the initial management? Orthop Traumatol Surg Res. 2013 Apr;99(2):175-82. doi: 10.1016/j.otsr.2012.12.014.

Benders KEM, Leenen LPH. Management of Hemodynamically Unstable Pelvic Ring Fractures. Front Surg. 2020 Dec4;7:601321. doi: 10.3389/fsurg.2020.601321.

Vaidya R, Waldron J, Scott A, Nasr K. Angiography and Embolization in the Management of Bleeding Pelvic Fractures. J Am Acad Orthop Surg. 2018 Feb 15;26(4):e68-e76. doi: 10.5435/JAAOS-D-16-00600.

Marzi I, Lustenberger T. Management of Bleeding Pelvic Fractures. Scand J Surg. 2014 Jun;103(2):104-111. doi: 10.1177/1457496914525604.

Suzuki T, Smith WR, Moore EE. Pelvic packing or angiography: competitive or complementary? Injury. 2009 Apr;40(4):343-53. doi: 10.1016/j.injury.2008.12.006.

Burlew CC. Preperitoneal pelvic packing for exsanguinating pelvic fractures. IntOrthop. 2017 Sep;41(9):1825-1829. doi: 10.1007/s00264-017-3485-3.

Moskowitz EE, Burlew CC, Moore EE, Pieracci FM, Fox CJ, Campion EM, Lawless RA, Cohen MJ. Preperitoneal pelvic packing is effective for hemorrhage control in open pelvic fractures. Am J Surg. 2018 Apr;215(4):675-677. doi: 10.1016/j.amjsurg.2017.

Martinez B, Breeding T, Katz J, Patel H, Santos RG, Elkbuli A. Outcomes of Preperitoneal Packing and Angioembolization for Hemorrhage Control in Hemodynamically Unstable Pelvic Fractures: A Systematic Review and Meta-Analysis. AmSurg. 2024 Mar;90(3):455-464. doi: 10.1177/00031348231216488.

McDonogh JM, Lewis DP, Tarrant SM, Balogh ZJ. Preperitoneal packing versus angioembolization for the initial management of hemodynamically unstable pelvic fracture: A systematic review and meta-analysis. J Trauma Acute Care Surg. 2022 May 1;92(5):931-939. doi: 10.1097/TA.0000000000003528.

Bosch U, Pohlemann T, Tscherne H. Strategiebei der Primär vers or gung von Beckenverletzungen [Primarymanagement of pelvicinjuries]. Orthopade. 1992 Nov;21(6):385-92. German. PMID: 1475124.

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