Transgenik Hayvan Üretimi

Kumar R. Therapeutic applications of transgenic animals. In: Animal Cell Technology: Basic & Applied Aspects: Proceedings of the Sixth International Meeting of the Japanese Association for Animal Cell Technology, Nagoya, Japan, 9-12 November, 1994; pp. 87-93.

Wegmann TG, Gilman JG. Chimerism for three genetic systems in tetraparental mice. Developmental Biology; 1970; 21(3): 281-291.

Gordon JW, Scangos GA, Plotkin DJ, et al. Genetic transformation of mouse embryos by microinjection of purified DNA. Proc. Natl. Acad. Sci; 1980; 77:7380-7384.

Gordon JW, Ruddle FH. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science; 1981; 214:1244-1246.

Pinkert CA, Murray JD. Transgenic farm animals. Transgenic animals in agriculture; 1999; pp.1-18.

Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell; 2006; 126:663-676.

Bağış H. Transgenik fare eldesine yönelik çalışmalar. İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü Doktora Tezi; 1994. İstanbul.

Bağış H, Pabuccuoğlu S. Studies on production of transgenic mice. Turk J Vet Anim Sci; 1997; 21:287-292.

Bağış H. Transgenik rodent üretimi. Journal of Clinical and Analytical Medicine; 2012; 80-85.

Bağış H, Aktoprakligil D, Mercan HO, et al. Stable transmission and transcription of Newfoundland Ocean pout type III fish antifreeze protein (AFP) gene in transgenic mice and hypothermic storage of mouse gamets with AFP. Mol Rep Dev; 2006a; 73:1404-1411.

Bağış H, Arat S, Mercan HO, et al. Stable transmission and expression of the hepatitis B virus genome in hybrid transgenic mouse until F10 generation. J Exp Zoo; 2006b; 305A(5):420-427.

Bağış H, Tas A, Kankavi O. Determination of the expression of fish antifreeze protein (AFP) in several tissues and serum of transgenic mice in f7 generation at the room temperatura. J Exp Zool Part A Ecol Genet Physiol; 2008a; 309:255-261.

Bağış H, Akkoç T, Tas A, et al. Cryogenic effect of antifreeze protein on transgenic mouse ovaries and production of live offspring by orthotopic transplantation of cryopreserved mouse ovaries. Mol Rep Dev; 2008b; 75:608-613.

Ünsal Ö. Transgenik hayvanların dünü, bugünü ve geleceği. Ege Üniversitesi Fen Bilimleri Enstitüsü Yüksek Lisans Tezi; 2018, İzmir.

Arat S, Rzucidlo SJ, Gibbons J, et al. Production of transgenic bovine embryos by transfer of transfected granulose cells into enucleated oocytes. Mol Reprod Dev; 2001; 60:20-26.

Arat S, Gibbons J, Rzucidlo SJ, et al. In vitro development of bovine nuclear transfer embryos from transgenic clonal lines of adult and fetal fibroblast cells of the same genotype. Biol Reprod; 2002; 66:1768-1774.

Anonim. https://www.istanbul.edu.tr/tr/haber/iu-turkiyenin-ilk-transgenik-tavsanlarini-uretti-6A0074006400340049003500450036006700640077003100 2024a. (Erişim Tarihi: 10 Ekim 2024).

Anonim. https://www.istanbul.edu.tr/tr/duyuru/ulkemizin-ilk-transgenik-kuzusu-cimen-istanbul-universitesinde-dogdu-6A0048004200420038004A00490031005300780073003100#:~:text=İstanbul%20Üniversitesi%20Veteriner%20Fakültesi%2C%20Dölerme,tanesi%20transgenik%20olarak%20dünyaya%20geldi 2024b. (Erişim Tarihi: 10 Ekim 2024).

Anonim. https://www.aa.com.tr/tr/bilim-teknoloji/transgenik-kuzu-ve-tavsan-ilac-sanayine-umut-oldu/177564 2024c. (Erişim Tarihi: 10 Ekim 2024).

Birler S, Pabuccuoğlu S, Demir K, et al. Production of cloned lambs: Transfer of early cleavage stage embryos to final recipients. J. Fac. Vet. Med. İstanbul Univ; 2010; 36(1): 1-8.

Kara U, Bekyürek T. Türkiye’de süt sığırcılığında reprodüktif biyoteknolojik yöntemlerin gelişimi. International Journal of Eastern Mediterranean Agricultural Research; 2020; 3(1): 63-82.

Ekici A, Aktopraklıgil D, Timur M, et al. The effect of linear versus circular vector on enhanced green flourasent protein (EGFP) expression in transgenic Zebrafish (Drario rerio). J Anim Vet Adv; 2010; 9:1238-1236.

Öztürk GB. Transgenik embriyo üretimi için koç spermatozoonlarının farklı yöntemlerle transfekte edilmesi. İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü Doktora Tezi. 2013. İstanbul.

Houdebine LM. Animal transgenesis and cloning. John Wiley & Sons. 2003: pp.1-32.

Giassetti MI, Maria FS, Assumpçao ME, et al. Genetic engineering and cloning: Focus on animal biotechnology. In: Genetic Engineering. IntechOpen. 2013. pp.1-95.

Ng P, Parks RJ, Cummings DT, et al. An enhanced system for construction of adenoviral vectors by the two plasmid rescue method. Hum Gene Ther; 2000; 11:693-699.

Chrenek P, Makarevic AV, Pivko HJ, et al. Transgenic farm animal production and application: mini review. Slovak J Anim Sci; 2010; 43(2):45-49.

Carter BJ. Adeno-associated virus and the development of adeno-associated virus vectors: a historical perspective. Mol Ther; 2004; 10:981-989.

Lusby E, Fife KH, Berns KI. Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA. J Virol; 1980; 34:402-409.

Linden RM, Ward P, Giraud C, et al. Site-specific integration by adeno-associated virus. Proc Natl Acad Sci; 1996; 93:11288-11294.

Srivastava A, Lusby EW, Berns KI. Nucleotide sequence and organization of the adeno-associated virus to genome. J Virol; 1983; 45:555-564.

Hosono T, Mizuguchi H, Katayama K, et al. Adenovirus vector-mediated doxycycline inducible RNA interference. Hum Gene Ther; 2004; 15:813-819.

Wold WSM, Ison MG. Adenoviruses. In: Knipe DM, How-ley PM (eds.), Fields virology. Lippincott Williams & Wilkins, Philadelphia. 2013. Pp.1732-1767.

Wall RJ. Pronuclear microinjection. Cloning & Stem Cells; 2001; 3(4).209-220.

DeMayo JL, Wang J, Liang D, et al. Genetically engineered mice by pronuclear DNA microinjection. Current protocols in mouse biology; 2012; 2(3):245-262.

Wolf E, Schernthaner W, Zakhartchenko V, et al. Transgenic technology in farm animals: progress and perspectives. Exp Physiol; 2000; 85:615-625.

Nagashima H, Fujimura T, Takahagi Y, et al. Development of efficient strategies for the production of genetically modified pigs. Theriogenology; 2003; 59:95-106.

Pinkert C. Transgenic animal technology. A Laboratory Handbook. 2nd Ed. Academic Press. 2002.

Yamanaka S. Pluripotent stem cell-based cell therapy-promise and challenges. Cell Stem Cell; 2020; 27:523-531.

Bronson SK, Smithies O. Altering mice by homologous recombination using embryonic stem cells. J Biol Chem; 1994; 269: 27155-27158.

Shakweer WME, Krivoruchko AY, Dessouki SM, et al. A review of transgenic animal techniques and their applications. Journal of Genetic Engineering and Biotechnology; 2023; 21(1):55.

Shakweer WME, Hafez YM, El-Sayed A, et al. Uptake of exogenous bovine GH-pmKate2-N expression vector by rams spermatozoa. Bull Nati Rese Cent; 2019; 43:1-10.

Wu GM, Nose K, Mori E, et al. Binding of foreign DNA to mouse sperm mediated by its MHC class II structure. Am J ReprodImmunol; 1990; 24:120-126.

Monika A, Szczygiel SM, W, et al. Expression of foreign DNA is associated with paternal chromosome degradation in intracytoplasmic sperm injection-mediated transgenesis in the mouse. Biol Reprod; 2003; 68(5):1903-1910.

Alexsia LR, Patricia JS, Smith GA. New tools to convert bacterial artificial chromosomes to a self-excising design and their application to a herpes simplex virus type 1 infectious clone. BMC Biotechnol; 2016; 16:1-8.

Chang K, Qian J, Jiang M, et al. Effective generation of transgenic pigs and mice by linker-based sperm-mediated gene transfer. BMC Biotechnol; 2002; 2:1-13.

Blanchard KT, Boekelheide K. Adenovirus mediated gene transfer to rat testis in vivo. Biol Reprod; (1997; 56:495-500.

Sato M, Ishikawa A, Kimura M. Direct injection of foreign DNA into mouse testis as a possible in vivo gene transfer system via epididymal spermatozoa. Mol Reprod; 2002; 61:49-56.

Yonezawa T, Furuhata Y, Hirabayashi K, et al. Detection of transgene in progeny at different developmental stages following testis-mediated gene transfer. Molecular Reproduction and Development; 2001; 60(2):96-201.

Campbell KHA. Background to nuclear transfer and its applications in agriculture and human therapeutic medicine. Journal of Anatomy; 2003; 267-275.

Wilmut I, Whitelaw CBA. Strategies for production of pharmaceutical proteins in milk. Reprod Fertil Dev; 1994; 6(5):625-630.

Denning C, Burl S, Ainslie A, et al. Deletion of the α(1,3) galactosyltransferase (GGTA1) gene and the prion protein (PrP) gene in sheep. Nat Biotechnol; 2001; 19(6):559-562.

Heyman Y, Vignon X, Chesn P, et al. Cloning in cattle: from embryo splitting to somatic nuclear transfer. Reprod Nutr Dev; 1998; 38(6):595-603.

McCreath KJ, Howcroft J, Campbell KH, et al. Production of genetargeted sheep by nuclear transfer from cultured somatic cells. Nature; 2000; 405:1066-1069.

Lai L, Prather RS. Progress in producing knockout models for xenotransplantation by nuclear transfer. Ann Med; 2002; 34:501-506.

Pinkert CA. Transgenic animal technology: alternatives in genotyping and phenotyping. Comparative medicine; 2003; 53(2):126-139.

Rong RJ, Wu PC, Lan JP, et al. Western blot detection of PMI protein in transgenic rice. Journal of Integrative Agriculture; 2016; 15(4):726-734.

Acker CM, Forest SK, Zinkowski R, et al. Sensitive quantitative assays for tau and phospho-tau in transgenic mouse models. Neurobiology of Aging; 2013; 34(1):338-350.

Wagner J, Thiele F, Ganten D. Transgenic animals as models for human disease. Clinical and Experimental Hypertension; 1995; 17(4):593-605.

Schenk D, Barbour R, Dunn W, et al. Immunization with Amyloid-β Attenuates Alzheimer-Disease-Like Pathology in the PDAPP Mouse. Nature; 1999; 400:173-177.

Murray F. The oncomouse that roared: Hybrid exchange strategies as a source of distinction at the boundary of overlapping institutions. American Journal of sociology, 2010; 116(2):341-388.

Bunce N, Hunt J. The AIDS Mouse. College of Physical Science University of Guelph. The Science Corner. 2004.

Petters RM, Sommer JR. 2000. Transgenic animals as models for human disease. Transgenic Res; 2000; 9:347-351.

Harvey BK, Richie CT, Hoffer BJ, et al. Transgenic animal models of neurodegeneration based on human genetic studies. J Neural Transm; 2011; 118:27-45.

Feany MB, Bender WW. A Drosophila Model of Parkinson’s Disease. Nature; 2000; 394-398.

Houdebine LM. Transgenic Animals. Harwood Academic Publishers. 1997. Pp.461-463.

Schnieke AE. Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei From Transfected Fetal Fibroblasts. Science; 1997; 278:2130-2133.

White V. “University of Florida Researchers Test Drug from Transgenic Sheep in Study at Shands at UF Teaching Hospital”. August 30, 1999.

Van Berkel PH, Welling MM, Geerts M, et al. Large scale production of recombinant human lactoferrin in the milk of transgenic cows. Nature biotechnology; 2002; 20(5):484-487.

Biotherapeutics GTC. Genzyme transgenics corporation announces first successful cloning of transgenic goats. 1999.

Gaffney T. Transgenic goats in science and industry. Dairy Goat Journal; 2003; 81(6):23-26.

Takeda A, Cooper K, Bird Aet al. Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation. Health Technol Assess; 2010; 14(42):1-209.

Houdebine LM. Impacts of genetically modified animals on the ecosystem and human activities. Global Bioethics; 2014; 25(1):3-18.

Bagle TR, Kunkulol RR, Baig MS, et al. Transgenic animals and their application in medicine. Int J Med Res Health Sci; 2012; 2(1):107-116.

Blanco J, Ratanpara SS. Transgenic Animals. Doctoral dissertation, Worcester Polytechnic Institute. 2012.

Cooper DK, Gollackner B, Sachs DH. Will the pig solve the transplantation backlog? Annu Rev Med; 2002; 53:133-147.

Wheeler MB. Transgenic animals in agriculture. Nat Educ Knowledge; 2013; 4(11):1.

Pennisi E, Normile D. Perserverance Leads to Cloned Pig in Japan. Science; 2000; 289:1118.

Shakweer WME, Abd EL-Rahman HH. Cloning, nucleotide sequencing, and bioinformatics analyses of growth hormone mRNA of Assaf sheep and Boer goats reared in Egypt. J Gen Eng Biotechnol; 2020; 18-30.

McPherron AC, Lee SJ. Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci; 1997; 94:12457-12461.

Pursel VG, Wall RJ, Solomon MB, et al. Transfer of ovine metallothionein-ovine growth hormone fusion gene into swine. J. Anim. Sci; 1997; 75: 2208 2214.

Devlin RH, Biagi CA, Yesaki TY, et al. Growth of domesticated transgenic fish. Nature; 2001; 409: 781-782.

Wheeler MB. The role of existing and emerging biotechnologies for livestock production: toward holism. Acta Sci Vet; 2010; 38(2):463-484.

Magnus PK, Lali FA. Transgenic milk. Veterinary; 2008; 1(10):319-320.

Melo EO, Canavessi AMO, Franco MM, et al. Animal transgenesis: state of the art and applications. J Appl Genet; 2007; 48(1):47-61.

Geel TM, Mclaughlin PM, Leij LF, et al. Pompe Disease: Current state of treatment modalities and animal models. Molecular Genetics and Metabolisma; 2007; 92:299-307.

Laible G, Smolenski G, Wheeler T, et al. Increased gene dosage for β- and κ-casein in transgenic cattle improves milk composition through complex effects. Sci Rep; 2016; 6:37607.

Pal A, Chakravarty AK. Disease resistance for different livestock species. Genetics and breeding for disease resistance of livestock; 2020; 271-296.

Chrenek P, Makarevic AV, Pivko HJ, et al. Transgenic farm animal production and application: mini review. Slovak J Anim Sci; 2010; 43(2):45-49.

Meidinger RG, Ajakaiye A, Fan MZ, et al. Digestive utilization of phosphorus from plant-based diets in the Cassie line of transgenic Yorkshire pigs that secrete phytase in the saliva. J Anim Sci; 2013; 91(3):1307-1320.

Frewer L, Shepherd R. Ethical concerns and risk perceptions associated with different applications of genetic engineering; interrelationships with the perceived need for regulation of the technology. Agric Hum Values; 1995; 12(1):48-57.

Godown RD. The Science of Biotechnology. In: Batra LR, Klassen W, (eds.), Public Perceptions of Biotechnology. 1987. Maryland: Agricultural Research Institute, Maryland.

Thompson PB. Ethics and agricultural biotechnology. Science of Food and Agriculture; 1993; 5(1):8-9.

Frewer LJ, Shepherd R, Sparks P. Biotechnology and food production: knowledge and perceived risk. British Food Journal; 1994; 9:26-33.

Wynne A. Frameworks of rationality in risk management: towards the testing of naive sociology. In: Brown J (eds.), Environmental Threats: Perception, Analysis and Management. 1989. Belhaven Press, London.

Hoban TJ and Kendall PA. Consumer attitudes about the use of biotechnology in agriculture and food production. North Carolina State University. 1992. Raleigh, NC.

Wall RJ, Laible G, Maga EA, et al. Animal productivity and genetic diversity: cloned and transgenic animals. Animal Agriculture’s Future through Biotechnology, Part 8. CAST Issue Paper Number 43 August 2009.

FAO/WHO Expert Consultation. Safety assessment of foods derived from genetically modified animals, including fish. FAO, Rome. 2004.

Royal Society. The use of genetically modified animals. The Royal Society, 2001, London, UK.

NRC. Animal biotechnology: science-based concerns. National Acadamies Press, 2002. Washington, DC

NRC. Safety of genetically engineered foods: approaches to assessing unintended health effects. National Acadamies Press, 2004. Washington DC. USA.

FAO/WHO. Food Standards Programme Codex Alimentarius Commission. 2008. FAO, Rome.

FDA-CVM. Guidance for industry: regulation of genetically engineered animals containing heritable recombinant DNA constructs. 2009.

Murray JD, Maga EA. Is there a risk from not using GE animals? Transgenic Research; 2010; 19:357-361.

Pursel VG, Bolt DJ, Miller KF, et al. Expression and performance in transgenic pigs. J Reprod Fertil; 1990; 40:235-245.

Nancarrow CD, Marshall JTA, Clarkson JL, et al. Expression and physiology of performance regulating genes in transgenic sheep. J Reprod Fertil; 1991; 43:277-291.

Kumar R. Therapeutic applications of transgenic animals. In: Animal Cell Technology: Basic & Applied Aspects: Proceedings of the Sixth International Meeting of the Japanese Association for Animal Cell Technology, Nagoya, Japan, 9-12 November, 1994; pp. 87-93.

Wegmann TG, Gilman JG. Chimerism for three genetic systems in tetraparental mice. Developmental Biology; 1970; 21(3): 281-291.

Gordon JW, Scangos GA, Plotkin DJ, et al. Genetic transformation of mouse embryos by microinjection of purified DNA. Proc. Natl. Acad. Sci; 1980; 77:7380-7384.

Gordon JW, Ruddle FH. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science; 1981; 214:1244-1246.

Pinkert CA, Murray JD. Transgenic farm animals. Transgenic animals in agriculture; 1999; pp.1-18.

Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell; 2006; 126:663-676.

Bağış H. Transgenik fare eldesine yönelik çalışmalar. İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü Doktora Tezi; 1994. İstanbul.

Bağış H, Pabuccuoğlu S. Studies on production of transgenic mice. Turk J Vet Anim Sci; 1997; 21:287-292.

Bağış H. Transgenik rodent üretimi. Journal of Clinical and Analytical Medicine; 2012; 80-85.

Bağış H, Aktoprakligil D, Mercan HO, et al. Stable transmission and transcription of Newfoundland Ocean pout type III fish antifreeze protein (AFP) gene in transgenic mice and hypothermic storage of mouse gamets with AFP. Mol Rep Dev; 2006a; 73:1404-1411.

Bağış H, Arat S, Mercan HO, et al. Stable transmission and expression of the hepatitis B virus genome in hybrid transgenic mouse until F10 generation. J Exp Zoo; 2006b; 305A(5):420-427.

Bağış H, Tas A, Kankavi O. Determination of the expression of fish antifreeze protein (AFP) in several tissues and serum of transgenic mice in f7 generation at the room temperatura. J Exp Zool Part A Ecol Genet Physiol; 2008a; 309:255-261.

Bağış H, Akkoç T, Tas A, et al. Cryogenic effect of antifreeze protein on transgenic mouse ovaries and production of live offspring by orthotopic transplantation of cryopreserved mouse ovaries. Mol Rep Dev; 2008b; 75:608-613.

Ünsal Ö. Transgenik hayvanların dünü, bugünü ve geleceği. Ege Üniversitesi Fen Bilimleri Enstitüsü Yüksek Lisans Tezi; 2018, İzmir.

Arat S, Rzucidlo SJ, Gibbons J, et al. Production of transgenic bovine embryos by transfer of transfected granulose cells into enucleated oocytes. Mol Reprod Dev; 2001; 60:20-26.

Arat S, Gibbons J, Rzucidlo SJ, et al. In vitro development of bovine nuclear transfer embryos from transgenic clonal lines of adult and fetal fibroblast cells of the same genotype. Biol Reprod; 2002; 66:1768-1774.

Anonim. https://www.istanbul.edu.tr/tr/haber/iu-turkiyenin-ilk-transgenik-tavsanlarini-uretti-6A0074006400340049003500450036006700640077003100 2024a. (Erişim Tarihi: 10 Ekim 2024).

Anonim. https://www.istanbul.edu.tr/tr/duyuru/ulkemizin-ilk-transgenik-kuzusu-cimen-istanbul-universitesinde-dogdu-6A0048004200420038004A00490031005300780073003100#:~:text=İstanbul%20Üniversitesi%20Veteriner%20Fakültesi%2C%20Dölerme,tanesi%20transgenik%20olarak%20dünyaya%20geldi 2024b. (Erişim Tarihi: 10 Ekim 2024).

Anonim. https://www.aa.com.tr/tr/bilim-teknoloji/transgenik-kuzu-ve-tavsan-ilac-sanayine-umut-oldu/177564 2024c. (Erişim Tarihi: 10 Ekim 2024).

Birler S, Pabuccuoğlu S, Demir K, et al. Production of cloned lambs: Transfer of early cleavage stage embryos to final recipients. J. Fac. Vet. Med. İstanbul Univ; 2010; 36(1): 1-8.

Kara U, Bekyürek T. Türkiye’de süt sığırcılığında reprodüktif biyoteknolojik yöntemlerin gelişimi. International Journal of Eastern Mediterranean Agricultural Research; 2020; 3(1): 63-82.

Ekici A, Aktopraklıgil D, Timur M, et al. The effect of linear versus circular vector on enhanced green flourasent protein (EGFP) expression in transgenic Zebrafish (Drario rerio). J Anim Vet Adv; 2010; 9:1238-1236.

Öztürk GB. Transgenik embriyo üretimi için koç spermatozoonlarının farklı yöntemlerle transfekte edilmesi. İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü Doktora Tezi. 2013. İstanbul.

Houdebine LM. Animal transgenesis and cloning. John Wiley & Sons. 2003: pp.1-32.

Giassetti MI, Maria FS, Assumpçao ME, et al. Genetic engineering and cloning: Focus on animal biotechnology. In: Genetic Engineering. IntechOpen. 2013. pp.1-95.

Ng P, Parks RJ, Cummings DT, et al. An enhanced system for construction of adenoviral vectors by the two plasmid rescue method. Hum Gene Ther; 2000; 11:693-699.

Chrenek P, Makarevic AV, Pivko HJ, et al. Transgenic farm animal production and application: mini review. Slovak J Anim Sci; 2010; 43(2):45-49.

Carter BJ. Adeno-associated virus and the development of adeno-associated virus vectors: a historical perspective. Mol Ther; 2004; 10:981-989.

Lusby E, Fife KH, Berns KI. Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA. J Virol; 1980; 34:402-409.

Linden RM, Ward P, Giraud C, et al. Site-specific integration by adeno-associated virus. Proc Natl Acad Sci; 1996; 93:11288-11294.

Srivastava A, Lusby EW, Berns KI. Nucleotide sequence and organization of the adeno-associated virus to genome. J Virol; 1983; 45:555-564.

Hosono T, Mizuguchi H, Katayama K, et al. Adenovirus vector-mediated doxycycline inducible RNA interference. Hum Gene Ther; 2004; 15:813-819.

Wold WSM, Ison MG. Adenoviruses. In: Knipe DM, How-ley PM (eds.), Fields virology. Lippincott Williams & Wilkins, Philadelphia. 2013. Pp.1732-1767.

Wall RJ. Pronuclear microinjection. Cloning & Stem Cells; 2001; 3(4).209-220.

DeMayo JL, Wang J, Liang D, et al. Genetically engineered mice by pronuclear DNA microinjection. Current protocols in mouse biology; 2012; 2(3):245-262.

Wolf E, Schernthaner W, Zakhartchenko V, et al. Transgenic technology in farm animals: progress and perspectives. Exp Physiol; 2000; 85:615-625.

Nagashima H, Fujimura T, Takahagi Y, et al. Development of efficient strategies for the production of genetically modified pigs. Theriogenology; 2003; 59:95-106.

Pinkert C. Transgenic animal technology. A Laboratory Handbook. 2nd Ed. Academic Press. 2002.

Yamanaka S. Pluripotent stem cell-based cell therapy-promise and challenges. Cell Stem Cell; 2020; 27:523-531.

Bronson SK, Smithies O. Altering mice by homologous recombination using embryonic stem cells. J Biol Chem; 1994; 269: 27155-27158.

Shakweer WME, Krivoruchko AY, Dessouki SM, et al. A review of transgenic animal techniques and their applications. Journal of Genetic Engineering and Biotechnology; 2023; 21(1):55.

Shakweer WME, Hafez YM, El-Sayed A, et al. Uptake of exogenous bovine GH-pmKate2-N expression vector by rams spermatozoa. Bull Nati Rese Cent; 2019; 43:1-10.

Wu GM, Nose K, Mori E, et al. Binding of foreign DNA to mouse sperm mediated by its MHC class II structure. Am J ReprodImmunol; 1990; 24:120-126.

Monika A, Szczygiel SM, W, et al. Expression of foreign DNA is associated with paternal chromosome degradation in intracytoplasmic sperm injection-mediated transgenesis in the mouse. Biol Reprod; 2003; 68(5):1903-1910.

Alexsia LR, Patricia JS, Smith GA. New tools to convert bacterial artificial chromosomes to a self-excising design and their application to a herpes simplex virus type 1 infectious clone. BMC Biotechnol; 2016; 16:1-8.

Chang K, Qian J, Jiang M, et al. Effective generation of transgenic pigs and mice by linker-based sperm-mediated gene transfer. BMC Biotechnol; 2002; 2:1-13.

Blanchard KT, Boekelheide K. Adenovirus mediated gene transfer to rat testis in vivo. Biol Reprod; (1997; 56:495-500.

Sato M, Ishikawa A, Kimura M. Direct injection of foreign DNA into mouse testis as a possible in vivo gene transfer system via epididymal spermatozoa. Mol Reprod; 2002; 61:49-56.

Yonezawa T, Furuhata Y, Hirabayashi K, et al. Detection of transgene in progeny at different developmental stages following testis-mediated gene transfer. Molecular Reproduction and Development; 2001; 60(2):96-201.

Campbell KHA. Background to nuclear transfer and its applications in agriculture and human therapeutic medicine. Journal of Anatomy; 2003; 267-275.

Wilmut I, Whitelaw CBA. Strategies for production of pharmaceutical proteins in milk. Reprod Fertil Dev; 1994; 6(5):625-630.

Denning C, Burl S, Ainslie A, et al. Deletion of the α(1,3) galactosyltransferase (GGTA1) gene and the prion protein (PrP) gene in sheep. Nat Biotechnol; 2001; 19(6):559-562.

Heyman Y, Vignon X, Chesn P, et al. Cloning in cattle: from embryo splitting to somatic nuclear transfer. Reprod Nutr Dev; 1998; 38(6):595-603.

McCreath KJ, Howcroft J, Campbell KH, et al. Production of genetargeted sheep by nuclear transfer from cultured somatic cells. Nature; 2000; 405:1066-1069.

Lai L, Prather RS. Progress in producing knockout models for xenotransplantation by nuclear transfer. Ann Med; 2002; 34:501-506.

Pinkert CA. Transgenic animal technology: alternatives in genotyping and phenotyping. Comparative medicine; 2003; 53(2):126-139.

Rong RJ, Wu PC, Lan JP, et al. Western blot detection of PMI protein in transgenic rice. Journal of Integrative Agriculture; 2016; 15(4):726-734.

Acker CM, Forest SK, Zinkowski R, et al. Sensitive quantitative assays for tau and phospho-tau in transgenic mouse models. Neurobiology of Aging; 2013; 34(1):338-350.

Wagner J, Thiele F, Ganten D. Transgenic animals as models for human disease. Clinical and Experimental Hypertension; 1995; 17(4):593-605.

Schenk D, Barbour R, Dunn W, et al. Immunization with Amyloid-β Attenuates Alzheimer-Disease-Like Pathology in the PDAPP Mouse. Nature; 1999; 400:173-177.

Murray F. The oncomouse that roared: Hybrid exchange strategies as a source of distinction at the boundary of overlapping institutions. American Journal of sociology, 2010; 116(2):341-388.

Bunce N, Hunt J. The AIDS Mouse. College of Physical Science University of Guelph. The Science Corner. 2004.

Petters RM, Sommer JR. 2000. Transgenic animals as models for human disease. Transgenic Res; 2000; 9:347-351.

Harvey BK, Richie CT, Hoffer BJ, et al. Transgenic animal models of neurodegeneration based on human genetic studies. J Neural Transm; 2011; 118:27-45.

Feany MB, Bender WW. A Drosophila Model of Parkinson’s Disease. Nature; 2000; 394-398.

Houdebine LM. Transgenic Animals. Harwood Academic Publishers. 1997. Pp.461-463.

Schnieke AE. Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei From Transfected Fetal Fibroblasts. Science; 1997; 278:2130-2133.

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