Kemik ve Eklem Hastalıklarında Beslenme

Barrere F, Van Blitterswijk CA, Groot K. Bone regeneration: Molecular and Cellular İnteractions with Calcium Phosphate Ceramics. International Journal of Nanomedicine. 2006; 1: 317-332.

Tunçay Ekin Ö. Biyomimetik yöntemle bor katkılı doku iskelelerinin geliştirilmesi ve kemik doku mühendisliğindeki etkinliklerinin araştırılması. Yüksek Lisans Tezi. Hacettepe Üniversitesi Fen Bilimleri Enstitüsü. 2013; 4-7, Ankara.

Walsh JS. Normal bone physiology, remodelling and its hormonal regulation. Surgery. 2015; 33: 1-6. https://doi.org/10.1016/j.mpsur.2014.10.010.

Bonjour J-P. Review Article Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney. Br J Nutr. 2013; 110: 1168-1177. https://doi.org/10.1017/S0007114513000962.

Wilson-Barnes SL, Susan A. Lanham-New SA, Lambert H. Modifiable risk factors for bone health & fragility fractures. Best Practice & Research Clinical Rheumatology. 2022; 36: 1-18. https://doi.org/10.1016/j.berh.2022.101758

Kini U, Nandeesh BN. Physiology of bone forma¬tion, remodeling, and metabolism. Fogelman I. et al. eds. Radionuclide and Hybrid Bone Imaging. Springer Press. Berlin-Heidelberg, 2012, p.30-55.

William OR. Functional anatomy and physiology of domestic animals. Fourth edition. 2009, p.179-198.

Buckwalter JA, Glimcher MJ, Cooper RR, Recker R. Bone biology. J Bone Joint Surg Am. 2010; 77: 1256-1275.

Hadjidakis JD, Androulakis II. Bone remodeling. Ann NY Acad Sci. 2006; 1092: 385-396.

Fradson RD, Spurgeon TL. Anatomy and Physiology of Farm Animals. Fifth edition. 1992, p. 55-81.

İnsal B, Pişkin İ. Kemik dokusunun fizyolojisi. Etlik Vet Mikrobiyol Derg. 2017; 28(1): 28-32.

Eroschenko VP. diFiore Histoloji Atlası Fonksiyonel İlişlileriyle. 10.baskı, Palme Yayınevi, Ankara. 2008.

Bassert JM, Colville T. Clinical anatomy and physi¬ology for veterinary technicians. 2002. p.95-118.

Bayliss L, Mahoney DJ, Monk P, (2012). Normal bone phys¬iology, remodeling and its hormonal regulation. Surgery. 2012; 30(2): 47-53.

Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. 2008; 3: 131-139.

Leibbrandt A, Penninger JM. RANK/RANKL: Regulators of ımmune responses and bone physiology. Ann NY Acad Sci. 2008; 1143: 123-150.

Topaloğlu U, Ketani MA, Güney Saruhan B. Kemik doku ve kemikleşme çeşitleri. Dicle Üniv Vet Fak Derg. 2017; 10(1): 62-71.

Shetty S, Kapoor N, Bondu JD, Thomas N, Paul TV. Bone turnover markers: emerging tool in the management of osteoporosis. Indian journal of endocrinology and metabolism. 2016; 20(6): 846-852.

Eastell R, Szulc P. Use of bone turnover markers in postmenopausal osteoporosis. The Lancet Diabetes and Endocrinology. 2017; 5(11): 908-923.

Kong YY, William JB, Penninger MJ. Osteoprotegerin ligand: a regulator of immune responses and bone physiology. Immunol Today. 2010; 21(10): 495-502.

Anderson JJ, Rondano P, Holmes A. Roles of diet and physical activity in the prevention of osteoporosis. Scand J Rheumatol Suppl. 1996; 103: 65-74.

Bailey DA, Martin AD, McKay HA et al. Calcium accretion in girls and boys during puberty: a longitudinal analysis. J Bone Miner Res. 2000; 15: 2245-2250.

Viljakainen HT. Factors influencing bone mass accrual: focus on nutritional aspects. Proceedings of the Nutrition Society. 2016; 75: 415-419.

Herwana E, Setiabudy R, Soegondo S, Baziad A, Hidayat A. Soy isoflavone supplementation reduces RANKL/OPG ratio on postmenopausal women with osteopenia. International Journal of Pharmaceutical Research. 2020; 12(4): 1820-1827.

Infante M, Fabi A, Cognetti F, Gorini S, Caprio M, Fabbri A. RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives. Journal of Experimental & Clinical Cancer Research. 2019; 38(1): 1-18.

Rachner TD, Kasimir-Bauer S, Göbel A, et al. Prognostic value of RANKL/OPG serum levels and disseminated tumor cells in nonmetastatic breast cancer. Clinical Cancer Research. 2019; 25(4): 136-1378.

Graham TR, Odero-Marah VA, Chung LW, Agrawal KC, Davis R, Abdel-Mageed AB. PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-κB in metastatic prostate cancer cells. The Prostate. 2009; 69(2): 168-180.

Carrillo-López N, Martínez-Arias L, Fernández-Villabrille S, et al. Role of the RANK/RANKL/OPG and Wnt/β-catenin systems in CKD bone and cardiovascular disorders. Calcified Tissue International. 2021; 108(4): 439-451.

Yari Z, Tabibi H, Najafi I, Hedayati M, Movahedian M. Effects of isoflavones on bone turnover markers in peritoneal dialysis patients: a randomized controlled trial. International Urology and Nephrology. 2020; 52(7): 1367-1376.

Sambrook P, Cooper C. Osteoporosis is a serious public health issue. The past 10 years have seen great advances in our understanding of its epidemiology, pathophysiology, and treatment, and further advances are rapidly being made. Clinical assessment will probably evolve from decisions mainly being made on the basis of bone densitometry, to use of algorithms of absolute osteoporosis. Lancet. 2006; 367(9527): 2010-2018.

Cauley JA. Estrogen and bone health in men and women. Steroids. 2015; 99: 11-15.

Graham TR, Odero-Marah VA, Chung LW, Agrawal KC, Davis R, Abdel-Mageed AB. PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-κB in metastatic prostate cancer cells. The Prostate. 2009; 69(2): 168-180.

Carrillo-López N, Martínez-Arias L, Fernández-Villabrille S, et al. Role of the RANK/RANKL/OPG and Wnt/β-catenin systems in CKD bone and cardiovascular disorders. Calcified Tissue International. 2021; 108(4): 439-451.

Brändström H, Björkman T, Ljunggren Ö. Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells. Biochemical and Biophysical Research Communications. 2001; 280(3): 831-835.

Marini H, Minutoli L, Polito F, et al. OPG and Srankl serum concentrations in osteopenic, postmenopausal women after 2-year genistein administration. Journal of Bone and Mineral Research. 2008; 23(5): 715-720.

Liu W, Zhang X. Receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin system in bone and other tissues (review). Molecular Medicine Reports. 2015; 11(5): 3212-3218.

Anderson DM, Maraskovsky E, Billingsley WL, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature. 1997; 390(6656): 17-179.

Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature. 2003; 423(6937): 337-342.

Noh D, Lim Y, Lee H, Kim H, Kwon O. Soybean-hop alleviates estrogen deficiency-related bone loss and metabolic dysfunction in ovariectomized rats fed a high-fat diet. Molecules. 2018; 23(5): 1205.

Bitto A, Burnett B, Polito F, et al. Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol. British Journal of Pharmacology. 2008; 155(6): 896-905.

Hendrickx G, Boudin E, Van Hul W. A look behind the scenes: the risk and pathogenesis of primary osteoporosis. Nat Rev Rheumatol. 2015; 11(8): 462-474. doi: 10.1038/nrrheum.2015.48.

Kanis JA, McCloskey EV, Johansson H, Oden A, Melton LJ. Khaltaev N. A reference standard for the description of osteoporosis. Bone. 2008; 42(3): 467-475. doi:10.1016/j.bone.2007.11.001.

Cosman F, de Beur SJ, LeBoff MS, et al. Clinician's guide to prevention and treatment of osteoporosis: A journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. Osteoporos Int. 2014; 25: 2359-2381. https://doi.org/10.1007/s00198-014-2794-2.

Papadopoulou SK, Papadimitriou K, Voulgaridou G, Georgaki E, Tsotidou E, Zantidou O, Papandreou D. Exercise and nutrition impact on osteoporosis and sarcopenia-The incidence of osteosarcopenia: A narrative review. Nutrients. 2021; 13: 1-14. https://doi.org/10.3390/nu13124499.

Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006; 17: 1726-1733.

Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, Muratore M, Casciaro S. Major osteoporotic fragility fractures: Risk factor updates and societal impact. World J. Orthop. 2016; 7: 171-181.

Gao Y, Patil S, Jia J. The development of molecular biology of osteoporosis. Int. J. Mol. Sci. 2021; 22: 8182.

Dhillon RJ, Hasni S. Pathogenesis and management of sarcopenia. Clin. Geriatr. Med. 2017; 33: 17-26.

Hunter GR, Singh H, Carter SJ, Bryan DR, Fisher G. Sarcopenia and its implications for Metabolic Health. J. Obes. 2019; 2019: 8031705.

Aaseth J, Boivin G, Andersen O. Osteoporosis and trace elements–an overview. J Trace Elem Med Biol. 2012; 26(2-3):149-152. doi: 10.1016/j.jtemb.2012.03.017

Ratajczak AE, Rychter AM, Zawada A, Dobrowolska A, Krela-Kazmierczak I. Do only calcium and vitamin D matter? Micronutrients in the diet of inflammatory bowel diseases patients and the risk of osteoporosis. Nutrients. 2021; 13(2): 525. doi: 10.3390/nu13020525

Zhang H, Wang A, Shen G, Wang X, Liu G, Yang F, et al. Hepcidin-induced reduction in iron content and PGC-1beta expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis. Aging (Albany NY). 2021; 13(8): 11296-11314. doi: 10.18632/aging.202817

Ceylan MN, Akdas S, Yazihan N. Is zinc an important trace element on bonerelated diseases and complications? A meta-analysis and systematic review from serum level, dietary intake, and supplementation aspects. Biol Trace Elem Res. 2021; 199(2): 535-549. doi: 10.1007/s12011-020-02193-w

Föger-Samwald U, Dovjak P, Azizi-Semrad U, Kerschan-Schindl K, Pietschmann P. Osteoporosis: Pathophysiology and therapeutic options. EXCLI J. 2020; 19: 1017-1037.

Mankin HJ, Radin EL. Structure and Function of Joints. D. J. McCary ve W. J. Kopman (Ed.). Arthritis and Allied Conditions: A Textbook of Rheumatolog. Philadelphia: Lea&Febige.1993. s:181-197.

Rogers J. The Paleopathology of Joint Disease. M. Cox ve S. Mays (Ed.). Human Osteology in Archaeology an Forensic Science. London: Greenwich Medical Media Ltd.2000. s.163-182.

Doherty M, Jones A, Cawston TE. Osteoarthritis In: Textbook of Rheumatology, Madison PJ, Isenberg DA, Woo P, Glass DN, editors. Oxford University Pres; 1998. s.1515-1553.

Savcı A, Bilik Ö. Ortopedi ve Travmatoloji Kliniğinde Geriatrik Değerlendirme. Deuhyo Ed. 2014; 7: 156-163.

Erdal ÖD. Eklem hastalıkları ve yaşam biçimi arasındaki ilişkiler: Anadolu neolitik topluluklarından örnekler. Edebiyat Fakültesi Dergisi. 2007; 24(2): 77-93.

Altındağ Ö, Sırmatel Ö, Tabur H. Diz osteoartriti olan hastalarda demografik özellikler ve klinik parametrelerle ilişkisi. Harran Üniversitesi Tıp Fakültesi Dergisi. 2006; 3: 62-66.

Roos EM, Arden NK. Strategies for the prevention of knee osteoarthritis. Nat Rev Rheumatol. 2016; 12(2): 92-101.

Göğüş F. Osteoartroz. In: Yazıcı H, Hamuryudan V, Sonsuz A, Ed. İç Hastalıkları. 1. Baskı. İstanbul: İstanbul Medikal Yayıncılık. İstanbul. 2005. p.1012-1015.

Hizmetli S, Tel H, Tel H, Yıldırım M. Self-care agency and status to maintain activities of daily living elderly people with osteoarthritis. Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi 2012; 15: 27-32.

Scrivo R, Vasile M, Müller-Ladner U, Neumann E, Valesini G. Rheumatic diseases and obesity: adipocytokines as potential comorbidity biomarkers for cardiovascular diseases. Mediators of inflammation. 2013; 2013.

Kulkarni K, Karssiens T, Kumar V, Pandit H. Obesity and osteoarthritis. Maturitas. 2016; 89: 22-28.

Arden NK, Perry TA, Bannuru RR, Bruyère O, Cooper C, Haugen IK, et al. Non-surgical management of knee osteoarthritis: Comparison of ESCEO and OARSI 2019 guidelines. Nat Rev Rheumatol. 2021; 17(1): 59-66.

Lespasio MJ, Piuzzi NS, Husni ME, Muschler GF, Guarino AJ, Mont MA. Knee osteoarthritis: a primer. Perm J. 2017; 21: 16-183.

Morris JL, Letson HL, Gillman R, Hazratwala K, Wilkinson M, McEwen P, et al. The CNS theory of osteoarthritis: opportunities beyond the joint. Semin Arthritis Rheum. 2019; 49(3): 331-336.

Sun X, Zhen X, Hu X, Li Y, Gu S, Gu Y, Dong H. Osteoarthritis in the middle-aged and elderly in China: prevalence and influencing factors. Int J Environ Res Public Health. 2019; 16(23): 4701.

Cope PJ, Ourradi K, Li Y, Sharif M. Models of osteoarthritis: the good, the bad and the promising. Osteoarthritis Cartilage. 2019; 27(2): 230-9.

Karataş T, Yılmaz E, Polat Ü. Osteoartrit yönetimi, yaşam kalitesi ve hemşirenin destekleyici rolü. SDÜ Tıp Fak Derg. 2022: 29(2): 265-271, doi: 10.17343/sdutfd.1017250

Marcora S, Lemmey AB, Maddison PJ. Dietary treatment of rheumatoid cachexia with beta-hydroxy-betamethylbutyrate, glutamine and arginine: a randomised controlled trial. Clin Nutr. 2005; 24(3): 442–454.

Gómez-Vaquero C, Nolla JM, Fiter J, Ramon JM, Concustell R, Valverde J, et al. Nutritional status in rheumatoid arthritis. Joint Bone Spine. 2001; 68(5): 403-409.

Grassi W, De Angelis R, Lamanna G, et al. The clinical features of rheumatoid arthritis. European Journal of Radiology. 1998; 27: 18-24.

Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. Lancet. 2010; 376: 1094-1108.

Kitas GD, Gabriel SE. Cardiovascular disease in rheumatoid arthritis: state of the art and future perspectives. Annals of the rheumatic diseases. 2011; 70(1): 8-14.

Bustamante MF, Agustín-Perez M, Cedola F, et al. Design of an anti-inflammatory diet (ITIS diet) for patients with rheumatoid arthritis. Contemporary clinical trials communications. 2020; 17: 100524.

Oğur H, Günaydın R, Rakıcıoğlu N. Romatoid artritli kadın hastalarda beslenme durumunun değerlendirilmesi. Bes Diy Derg. 2020; 48(1): 63-72.

Zhen H, Gui F. The role of hyperuricemia on vascular endothelium dysfunction. Biomedical Reports. 2017; 7(4): 325-330.

Hirschfeld Hp, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017; 28(10): 2781-2790.

Kirk B, Al Saedi A, Duque G. Osteosarcopenia: a case of geroscience. Aging Med (Milton). 2019; 2(3): 147-156.

Kutsal YG, Özdemir O, Sarıdoğan FM, Günendi Z, Küçükdeveci AA, Kirazlı Y, et al. Osteosarkopeni: Klinik perspektif. Turk j Osteoporos. 2020; 26(2): 47-57.

Can B, Şanlıer N. Osteosarkopenide Beslenme Yaklaşımları: Geleneksel Derleme. Türkiye Klinikleri J Health Sci. 2022; 7(4): 1216-1225.

Harris SS, Dowson-Hudges B. Weight, body composition and bone density in postmenopausal women. Calcif Tissue Int. 1996; 59: 428-432.

Manzoni P, Brambilla P, Pietrobelli A, Beccaria L, Bianchessi A, Mora S, Chiumello G. Influence of body composition on bone mineral content in children and adolescents. Am J Clin Nutr. 1996; 64: 603-607.

Milos G, Moergeli H, Sob C, et al. Positive effect of Teriparatide on areal bone mineral density in young women with anorexia nervosa: a pilot study. Calcif Tissue Int. 2021; 108: 595-604. https://doi.org/10.1007/S00223-020-00791-3.

Park JH, Song YM, Sung J, Lee K, Kim YS, Kim T, et al. The association between fat and lean mass and bone mineral density: The Healthy Twin Study. Bone. 2012; 50: 1006-1011.

Yoo HJ, Park MS, Yang SJ, Kim TN, Lim K Il, Kang HJ, et al. The differential relationship between fat mass and bone mineral density by gender and menopausal status. J Bone Miner Metab. 2012; 30: 47-53.

Hu WW, Zhang H, Wang C, Gu JM, Yue H, Ke YH, et al. Lean mass predicts hip geometry and bone mineral density in Chinese men and women and age comparisons of body composition. J Clin Densitom 2012;15:434-42.

Kılınçarslan MG, Şahin EM, Sarıgül B, Kocaoğlu SB. Postmenopozal Türk Kadınlarında Vücut Kompozisyonu ve Fiziksel Aktivitenin Kemik Mineral Yoğunluğu ile İlişkisi. Turk J Osteoporos. 2020; 26: 70-74.

Liu Y, Xu Y, Wen Y, Guan K, Ling W, He L, et al. Association of weight-adjusted body fat and fat distribution with bone mineral density in middle-aged Chinese adults: A cross-sectional study. PLoS One 2013;8:e63339.

Chain A, Crivelli M, Faerstein E, Bezerra FF. Association between fat mass and bone mineral density among Brazilian women differs by menopausal status: The Pró-Saúde Study. Nutrition 2017;33:14-9.

Ho-Pham LT, Nguyen UDT, Nguyen TV. Association between lean mass, fat mass, and bone mineral density: A Meta-analysis. J Clin Endocrinol Metab. 2014; 99: 30-38.

Gümüş K, Ünsal A. Osteoartritli bireylerin günlük yaşam aktivitelerinin değerlendirilmesi. Türk Osteoporoz Dergisi. 2014; 20: 117-124.

Koçak B, Yüksel A. Kemik-eklem hastalıklarının obezite ile ilişkisi. Sağlık ve Yaşam Bilimleri Dergisi. 2021. 3(1): 97-100. doi: 10.33308/2687248X.202131205.

Ilich JZ, BrownbilI RA, Tamborini L: Bone and nutrition in elderly vvomen: protein, energy, and calcium as main determinants of bone mineral density. European Journal of Clinical Nutrition. 2003; 57: 554-565.

Sarıbay GF, Başaran A, Akın S, Korkusuz F. Beslenme ve kemik mineral yoğunluğu ilişkisi. Beslenme ve Diyet Dergisi. 2005; 33(2): 57-69.

Cloutier GR, Barr SI. Protein and bone health: Literature review and counseling implications. Canadian Journal of Dietetic Practice and Research. 2003; 64: 5-11.

Massey LK. Dietary animal and plant protein and human bone health: A whole foods approach. Journal of Nutrition. 2003; 133: 862-865.

Skov AR, Haulrik N, Toubro S, Molgaard C, Astrup A: Effect of protein intake on bone mineralization during weight loss: A 6 -month trial. Obesity Research. 2002;10: 432-438.

Bunker VW. The role o f nutrition in osteoporosis. British Journal of Biomedical Science. 1994;51: 228-240.

Rapuri PB, Gallagher JC, Haynatzka V. Protein intake: effects on bone mineral density and the rate of bone loss in elderly women. American Journal o f Clinical Nutrition. 2003; 77: 1517-1525.

Wohl GR, Loehrke L, VVatkins BA, Zernicke RF. Effects of high-fat diet on mature bone mineral content, structure, and mechanical properties. Calcified Tissue International. 1998; 63: 74-79.

Rigotti NA, Nussbaum SR, Herzog DB, Neer RM. Osteoporosis in women with anorexia nervosa. N Engl J Med. 1984; 311: 1601-1606. https://doi.org/ 10.1056/ NEJM198412203112503.

Zipfel S, Seibel MJ, Lowe B, et al. Osteoporosis in eating disorders: a follow-up study of patients with anorexia and bulimia nervosa. J Clin Endocrinol Metab. 2001; 86: 5227-5233. https://doi.org/10.1210/JCEM.86.11.8050.

Legroux I, Cortet B. Factors influencing bone loss in anorexia nervosa: assessment and therapeutic options. RMD Open. 2019; 5: 001009. https://doi.org/10.1136/RMDOPEN-2019-001009.

Micali N, Martini MG, Thomas JJ, et al. Lifetime and 12-month prevalence of eating disorders amongst women in mid-life: a population-based study of diagnoses and risk factors. BMC Med 2017; 15. https://doi.org/10.1186/S12916-016-0766-4.

Plasqui G. The role of physical activity in rheumatoid arthritis. Physiol Behav. 2008; 94(2): 270-275.

Elma Ö, Tümkaya Yilmaz S, Deliens T, Coppieters I, Clarys P, Nijs J, et al. Do nutritional factors interact with chronic musculoskeletal pain? A systematic review. J Clin Med. 2020; 9(3): 702.

Kutsal YG, Özdemir O, Sarıdoğan FM, Günendi Z, Küçükdeveci AA, Kirazlı Y, et al. Osteosarkopeni: Klinik perspektif. Turk j Osteoporos. 2020; 26(2): 47-57.

Marzetti E, Calvani R, Tosato M, Cesari M, Di Bari M, Cherubini a, et al; SPRINTT Consortium. Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging Clin Exp Res. 2017; 29(1): 35-42.

Kirk B, Zanker J, Duque G. Osteosarcopenia: epidemiology, diagnosis, and treatment-facts and numbers. J Cachexia sarcopenia Muscle. 2020; 11(3): 609-618.

Ilich JZ, Kelly OJ, Kim Y, Spicer MT. Low-grade chronic inflammation perpetuated by modern diet as a promoter of obesity and osteoporosis. Arh Hig Rada Toksikol. 2014; 65(2): 139-148.

Chew J, Yeo A, Yew S, Tan CN, Lim JP, Hafizah Ismail N, et al. Nutrition mediates the relationship between osteosarcopenia and frailty: a pathway analysis. Nutrients. 2020; 12(10): 2957.

Logue DM, Madigan SM, Melin A, et al. Low energy availability in athletes 2020: An updated narrative review of prevalence, risk, within-day energy balance, knowledge, and impact on sports performance. Nutrients. 2020;12. https://doi.org/10.3390/NU12030835.

Mountjoy M, Sundgot-Borgen JK, Burke LM, et al. IOC consensus statement on relative energy deficiency in sport (RED-S): 2018 update. Br J Sports Med. 2018; 52: 687-697. https://doi.org/10.1136/bjsports-2018-099193.

Carruth BR and Skinner JD: Dietary intake of females recovered from disordered eating. Journal of the Amcrican Dietctic Association. 1997; 97: A17.

Sarazin M, Alexandre C, Thomas T. Influence on bone metabolism of dietary trace elements, protein, fat, carbohydrates, and vitamins. Joint Bone Spine. 2000; 67: 408-418.

Trichopoulou A, Georgiou E, Bassiakos Y, Lipworth L, Lagiou P, Proukakis C, Trichopoulos D: Energy intake and monounsaturated fat in relation to bone mineral density among women and men in Greece. Preventive Medicine. 1997; 26: 395-400.

He J, Wang Y, Feng M, et al. Dietary intake and risk of rheumatoid arthritis-a cross section multicenter study. Clin Rheumatol. 2016; 35(12) :2901-2908.

Rondanelli M, Perdoni F, Peroni G, Caporali R, Gasparri C, Riva A, et al. Ideal food pyramid for patients with rheumatoid arthritis: A narrative review. Clin Nutr. 2021; 40(3):661-689.

Darling AL, Manders RJF, Sahni S, et al. Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years. Osteoporos Int 2019; 30: 741-761. https://doi.org/10.1007/s00198-019-04933-8.

Papageorgiou M, Dolan E, Elliott-Sale KJ, Sale C. Reduced energy availability: implications for bone health in physically active populations. Eur J Nutr. 2018;57:847e59. https://doi.org/10.1007/s00394-017-1498-8.

Frassetto L, Banerjee T, Powe N, Sebastian A. Acid balance, dietary acid load, and bone effects-A controversial subject. Nutrients. 2018; 10: 517. https://doi.org/10.3390/nu10040517.

Galchenko A, Gapparova K, Sidorova E. The influence of vegetarian and vegan diets on the state of bone mineral density in humans. Crit Rev Food Sci Nutr. 2021;1-17. https://doi.org/10.1080/10408398.2021.1996330.

Yoo JI, Lee KH, Choi Y, Lee J, Park YG. Poor dietary protein intake in elderly population with sarcopenia and osteosarcopenia: a nationwide population-based study. J Bone Metab. 2020; 27(4): 301-310.

Berner La, Becker g, Wise M, Doi j. Characterization of dietary protein among older adults in the United states: amount, animal sources, and meal patterns. j acad Nutr Diet. 2013;113(6):809-15.

Granic A, Mendonça N, Sayer AA, Hill TR, Davies K, Siervo M, et al. Effects of dietary patterns and low protein intake on sarcopenia risk in the very old: the Newcastle 85+ study. Clin Nutr. 2020; 39(1): 166-173.

Kaner G, Çalık G, Eren E, Gerdan V. Romatoid artritte tıbbi beslenme tedavisine yönelik yaklaşımlar. Bes Diy Derg. 2021; 49(1): 75-81.

Çalık, Y, Yazıcı S, Baş E, Ataoğlu S. Postmenopozal kadınlarda lipid düzeyleri ve kemik mineral yoğunluğu arasındaki ilişki. Düzce Tıp dergisi. 2010; 12(2): 30-35.

Diascro Jr DD, Vogel RL, Johnson TE, Witherup KM, Pitzenberger SM, Rutledge SJ, Prescott DJ, Rodan GA, Schmidt A: High fatty acid content in rabbit serum is responsible fort he differentiation of the osteoblasts into adipocyte-like cells. J Bone Miner Res.1998;13: 96-106.

Demer LL, Perhami F. Arterial calcification in face of osteoporosis in aging: can web lame oxidized lipids? Curr Opin Lipidol. 1997; 8: 312-314.

Parhami F, Garfinkel A, Demer LL: Role of lipids in osteoporosis. Arterioscler Thromb Vasc Biol. 2000; 20: 2346-2348.

Cerrahoğlu L, Duruöz MT, Şenocak İ: Postmenopozal osteoporozda yüksek kolesterol düzeyi ile kemik mineral yoğunluğunun ilişkisi. Türk Fiz Reh Dergisi. 2000;12: 23-27.

Yamaguchi T, Sugimoto T, Yamauchi M, Sowa H, Chen Q, Chihara K. Plasma lipids and osteoporosis in postmenopausal women. Endocr J. 2002; 49: 211–217.

Solomon DH, Avorn J, Canning CF, Wang PS: Lipids levels and bone mineral density. The American Journal of Medicine. 2002; 118: 1414-1418.

Linos A, Kaklamani V, Kaklamani E, Koumantaki Y, GiziakiE, Papazoglou S, et al. Dietary factors in relation to rheumatoid arthritis: a role for olive oil and cooked vegetables? Am J Clin Nutr. 1999; 70: 1077-1082.

Gioia C, Lucchino B, Tarsitano MG, Iannuccelli C, Di Franco M. Dietary habits and nutrition in rheumatoid arthritis: Can diet influence disease development and clinical manifestations? Nutrients. 2020; 12(5): 1456.

Lavado-Garcia JM, Roncero-Martin R, Moran JM, Pedrera-Canal M, Aliaga I, Leal-Hernández O, Martin, S.R, Canal-Macias ML. Long-chain omega-3 polyunsaturated fatty acid dietary intake is positively associated with bone mineral density in normal and osteopenic Spanish women. PLoS ONE. 2018; 13: 0190539.

Roncero-Martín R, Aliaga I, Moran J, Puerto-Parejo L, Rey-Sánchez P, de la Luz Canal-Macías M, Sánchez-Fernández A, Pedrera-Zamorano J, López-Espuela F, Vera V, et al. Plasma fatty acids and quantitative ultrasound, DXA and pQCT derived parameters in postmenopausal Spanish women. Nutrients. 2021; 13: 1454.

Shen D, Zhang X, Li Z, Bai H, Chen L. Effects of omega-3 fatty acids on bone turnover markers in postmenopausal women: systematic review and meta-analysis. Climacteric. 2017; 20(6): 522-527.

Gómez EF, Kaufer-Horwitz M, Mancera-Chávez GE. Medical Nutrition Therapy for Rheumatic Disease. In: Mahan KL, Raymond JL, editors. Krause’s Food & The Nutrition Care Process-E Book. 14th ed. Kanada: Elsevier Health Sciences; p.2017.

Cruz-jentoft AJ, Landi F, Schneider SM, Zú-Iga C, Arai H, Boirie Y, et al. Prevalence of and interventions for sarcopenia in ageing adults: A systematic review. Report of the International sarcopenia Initiative (EWgsOp and IWgs). Age Ageing. 2014; 43(6): 748-759.

Fonolla-Joya J, Reyes-García R, García-Martín A, López-Huertas E, Muoz-Torres M. Daily intake of milk enriched with n-3 fatty acids, oleic acid, and calcium improves metabolic and bone biomarkers in postmenopausal women. J Am Coll Nutr. 2016; 35(6): 529-536.

Sadeghi O, Djafarian K, Ghorabi S, Khodadost M, Nasiri M, Shab-Bidars. Dietary intake of fish, n-3 polyunsaturated fatty acids and risk of hip fracture: A systematic review and meta-analysis on observational studies. Crit Rev Food Sci Nutr. 2019; 59(8): 1320-1333.

Aaseth J, Boivin G, Andersen O. Osteoporosis and trace elements-an overview. J. Trace. Elem. Med. Biol. 2012; 26: 149-152.

Tessier AJ, Chevalier S. An update on protein, leucine, omega-3 fatty acids, and vitamin D in the prevention and treatment of sarcopenia and functional decline. Nutrients. 2018; 10(8): 1099.

Makida K, Nishida Y, Morita D, Ochiai S, Higuchi Y, Seki T, et al. Low energy irradiation of narrow-range UV-LED prevents osteosarcopenia associated with vitamin D deficiency in senescence accelerated Mouse prone 6. Sci Rep. 2020; 10(1): 11892.

Abidin NZ, Mitra SR. Total VS. Bioavailable: determining a better 25(OH)D index in association with bone density and muscle mass in postmenopausal women. Metabolites. 2020; 11(1): 23.

Hirschfeld HP, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017; 28(10): 2781-2790.

LeBoff M, Greenspan S, Insogna K, et al. The clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 2022. https://doi.org/10.1007/S00198-021-05900-Y

Reid IR, Bolland MJ, Grey A. Effects of vitamin D supplements on bone mineral density: A systematic review and meta-analysis. Lancet. 2014; 383: 146-155. https://doi.org/10.1016/S0140-6736(13)61647-5

Khaw K, Stewart A, Waayer D, et al. Effect of monthly high-dose vitamin D supplementation on falls and non-vertebral fractures: secondary and post-hoc outcomes from the randomised, double-blind, placebo-controlled ViDA trial. Lancet Diabetes Endocrinol. 2017; 5(8): 438-447. https://doi.org/10.1016/S2213-8587(17)30103-1

Manios Y, Moschonis G, Mavrogianni C, van den Heuvel E, Singh-Povel CM, Kiely M, Cashman KD. Reduced-fat Gouda-type cheese enriched with vitamin D3 effectively prevents vitamin D deficiency during winter months in postmenopausal women in Greece. Eur. J. Nutr. 2017; 56: 2367-2377.

Moran JM. Nutrition and Women’s Bone Health. Nutrients. 2022; 14: 763. https://doi. org/10.3390/nu14040763

Sharma J, Heagerty R. Stress fracture: A review of the pathophysiology, epidemiology and management options. J Fract Sprains. 2017. Available: https://www. researchgate.Net/ publication/320719800

Silk LN, Greene DA, Baker MK. The effect of calcium or calcium and vitamin D supplementation on bone mineral density in healthy males: a systematic review and meta-analysis. Int J Sport Nutr Exerc Metabol. 2015; 25: 510-524. https://doi. org/ 10. 1123/ ijsnem. 2014-0202

Wilson G, FraserW, Sharma A, et al. Markers of bone health, renal function, liver function, anthropometry and perception of mood: a comparison between flat and national hunt Jockeys. Int J Sports Med. 2012; 34: 453-459. https://doi.org/10.1055/s-0032-1321898

Vallibhakara, S.A.-O, Nakpalat K, Sophonsritsuk A, Tantitham C, Vallibhakara O. Effect of vitamin e supplement on bone turnover markers in postmenopausal osteopenicwomen: A double-blind, randomized, placebo-controlled trial. Nutrients. 2021; 13: 4226.

Kim D, Han A, Park Y. Association of dietary total antioxidant capacity with bone mass and osteoporosis risk in korean women: analysis of the korea national health and nutrition examination survey 2008-2011. Nutrients. 2021; 13: 1149.

Aksu M, Yöney B. Romatoid artrite güncel beslenme yaklaşımları. Current Perspectives on Health Sciences. 2023; 4(3): 96-103.

Cutolo M, Otsa K, Uprus M, Paolino S, Seriolo B. Vitamin D in rheumatoid arthritis. Autoimmun Rev. 2007; 7(1): 59-64.

Meena N, Singh Chawla SP, Garg R, Batta A, Kaur S. Assessment of vitamin d in rheumatoid arthritis and ıts correlation with disease activity. J Nat Sci Biol Med. 2018; 9(1): 54-58.

Harrison SR, Li D, Jeffery LE, Raza K, Hewison M. Vitamin D, autoimmune disease and rheumatoid arthritis. Calcif Tissue Int. 2020; 106(1): 58-75.

Holick MF. Resurrection of vitamin D deficiency and rickets. J Clin Investig. 2006; 116: 2062-2072. https://doi.org/10.1172/JCI29449.

Yabancı N, Pekcan G. Adolesanlarda beslenme durumu ile fiziksel aktivite düzeyinin vücut bileşimi ve kemik mineral yoğunluğu üzerine etkisi. Aile ve Toplum. 2010; 11(6): -20.

Massey LK, Hollingbery PW. Acute effects of dietary caffeine and sucrose on urinary mineral excretion of healthy adolescents. Nutr Res. 1998; 8: 1005.

Hoover PA, Wabber CE, Beaumont LF, and Blake JM. Postmenopausal bone mineral density: Relationship to calcium intake, calcium absorption, residual estrogen, body composition and physical activity. Can J Physiol Pharmacol. 1996; 74: 911-917.

Marusic A, Kos K, Stavljenic A, Vukicevic S. Acute zinc deficiency and trabecular bone loss in rats with talc granulomatosis. Nutr Abs Rev. 1993; 63(4): 338.

Specker BL. Evidence for an interaction between calcium intake and physical activity on changes in bone mineral density. J Bone Miner Res. 2009; 11: 1539-1544. https://doi. org/ 10.1002/jbmr.5650111022.

Green JH, Booth C, Bunning R. Acute effect of high-calcium milk with or without additional magnesium, or calcium phosphate on parathyroid hormone and biochemical markers of bone resorption. Eur J Clin Nutr. 2003; 57: 61-68. https://doi.org/ 10.1038/sj.ejcn. 1601501.

Cadogan J, Eastell R, Jones N, Barker ME. Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial. BMJ (Clinical research ed). 1997; 315: 1255-1260. https://doi.org/10.1136/BMJ.315.7118.1255.

Lambert HL, Eastell R, Karnik K, et al. Calcium supplementation and bone mineral accretion in adolescent girls: an 18-month randomized controlled trial with 2-y follow-up. Am J Clin Nutr. 2008; 87: 455-462. https://doi.org/10.1093/AJCN/87.2.455.

Aloia J, Bojadzievski T, Yusupov E, et al. The relative influence of calcium intake and vitamin D status on serum parathyroid hormone and bone turnover biomarkers in a double-blind, placebo-controlled parallel group, longitudinal factorial design. J Clin Endocrinol Metabol. 2010; 95: 3216-3224. https://doi.org/10.1210/jc.2009-1294.

Kanadys W, Barańska A, Błaszczuk A, et al. Effects of soy isoflavones on biochemical markers of bone metabolism in postmenopausal women: a systematic review and metaanalysis of randomized controlled trials. International Journal of Environmental Research and Public Health. 2021; 18(10): 5346.

Herwana E, Setiabudy R, Soegondo S, Baziad A, Hidayat A. Soy isoflavone supplementation reduces RANKL/OPG ratio on postmenopausal women with osteopenia. International Journal of Pharmaceutical Research. 2020; 12(4): 1820-1827.

Lv Z, Yan S, Li G, Liu D, Guo Y. Genistein improves the reproductive performance and bone status of breeder hens during the late egg-laying period. Poultry Science. 2019, 98(12): 7022-7029.

Nakai S, Fujita M, Kamei Y. Health promotion effects of soy isoflavones. Journal of Nutritional Science and Vitaminology. 2020; 66(6): 502-507.

Scheiber MD, Liu JH, Subbiah M, Rebar RW, Setchell KD. Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women. Menopause. 2001; 8(5): 384-392.

Liu W, Zhang X. Receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin system in bone and other tissues (review). Molecular Medicine Reports. 2015; 11(5): 3212-3218.

Hooshiar SH, Tobeiha M, Jafarnejad S. Soy Isoflavones and Bone Health: Focus on the RANKL/RANK/OPG Pathway. BioMed Research International. 2022; 1-10. https://doi.org/10.1155/2022/8862278

Nayeem F, Chen N-W, Nagamani M, Anderson KE, Lu LJ-W. Daidzein and genistein have differential effects in decreasing whole body bone mineral density but had no effect on hip and spine density in premenopausal women: a 2-year randomized, double-blind, placebo-controlled study. Nutrition Research. 2019; 68: 70-81.

Chen W-F, Wong M-S. Genistein modulates the effects of parathyroid hormone in human osteoblastic SaOS-2 cells. British Journal of Nutrition. 2006; 95(6): 1039-1047.

Tit DM, Bungau S, Iovan C, et al. Effects of the hormone replacement therapy and of soy isoflavones on bone resorption in postmenopause. Journal of Clinical Medicine. 2018; 7(10): 297.

Santos M, Florencio-Silva R, Medeiros V. et al. Effects of different doses of soy isoflavones on bone tissue of ovariectomized rats. Climacteric. 2014; 17(4): 393-401.

Lanham-New SA, Lambert H, Frassetto L. Potassium. Advances in Nutrition. 2012; 3: 820. https://doi.org/10.3945/AN.112.003012.

Martiniakova M, Babikova M, Mondockova V, et al. The role of macronutrients, micronutrients and flavonoid polyphenols in the prevention and treatment of osteoporosis. Nutrients. 2022; 14. https://doi.org/10.3390/NU14030523.

Nieves JW. Osteoporosis: The role of micronutrients. Am J Clin Nutr. 2005; 81. https://doi.org/10.1093/AJCN/81.5.1232.

Pietschmann N, Rijntjes E, Hoeg A, Stoedter M, Schweizer U, Seemann P, et al. Selenoprotein P is the essential selenium transporter for bones. Metallomics. 2014; 6(5): 1043–9. doi: 10.1039/C4MT00003J

Manolagas SC. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev. 2010, 31(3): 266-300. doi: 10.1210/er.2009-0024

Zhou H, Wang T, Li Q, Li D. Prevention of keshan disease by selenium supplementation: a systematic review and meta-analysis. Biol Trace Elem Res. 2018; 186(1): 98-105. doi: 10.1007/s12011-018-1302-5.

Winther KH, Rayman MP, Bonnema SJ, Hegedus L. Selenium in thyroid disorders - essential knowledge for clinicians. Nat Rev Endocrinol. 2020; 16(3): 165-76. doi: 10.1038/ s41574-019-0311-6

Galvez-Fernandez M, Grau-Perez M, Garcia-Barrera T, Ramirez-Acosta S, Gomez-Ariza JL, Perez-Gomez B, et al. Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The HORTEGA study. Free Radic Biol Med. 2021; 162: 392-400. doi: 10.1016/j.freeradbiomed.2020.10.318

Wang Y, Xie D, Li J, Long H, Wu J, Wu Z, et al. Association between dietary selenium intake and the prevalence of osteoporosis: A cross-sectional study. BMC Musculoskelet Disord. 2019; 20(1): 585. doi: 10.1186/s12891-019-2958-5

Xue G, Liu R. Association between dietary selenium intake and bone mineral density in the US general population. Ann Transl Med. 2022; 10(16): 869. doi:10.21037/atm-22-3441

Peng S, Zhang G, Wang D. Association of selenium intake with bone mineral density and osteoporosis. The national health and nutrition examination survey. Frontiers in Endocrinology. 2023. 1-11. Doi. 10.3389/fendo.2023.1251838

Wolf RL, Cauley JA, Pettinger M, Jackson R, Lacroix A, Leboff MS, et al. Lack of a relation between vitamin and mineral antioxidants and bone mineral density: results from the Women’s Health Initiative. Am J Clin Nutr. 2005; 82(3): 581-588. doi: 10.1093/ajcn/82.3.581

Walsh JS, Jacques RM, Schomburg L, Hill TR, Mathers JC, Williams GR, et al. Effect of selenium supplementation on musculoskeletal health in older women: a randomised, double-blind, placebo-controlled trial. Lancet Healthy Longev. 2021; 2(4): 212-221. doi: 10. 1016/S2666-7568(21)00051-9

Xie H, Wang N, He H, Yang Z, Wu J, Yang T, et al. The association between selenium and bone health: a meta-analysis. Bone Joint Res. 2023; 12(7): 423-432. doi: 10. 1302/2046-3758.127.BJR-2022-0420.R1

Zhang J, Munger RG, West NA, Cutler DR, Wengreen HJ, Corcoran CD. Antioxidant intake and risk of osteoporotic hip fracture in Utah: an effect modified by smoking status. Am J Epidemiol. 2006; 163(1): 9-17. doi: 10.1093/aje/kwj005

Hardcastle AC, Aucott L, Fraser WD, et al. Dietary patterns, bone resorption and bone mineral density in early postmenopausal Scottish women. Eur J Clin Nutr. 2011; 65: 378-385. https://doi.org/10.1038/ejcn.2010.264.

Gannon RHT, Millward DJ, Brown JE, et al. Estimates of daily net endogenous acid production in the elderly UK population: Analysis of the National Diet and Nutrition Survey (NDNS) of British adults aged 65 years and over. 2019. https:// doi.org/ 10. 1017/ S0007114508901240.

Gioia C, Lucchino B, Tarsitano MG, Iannuccelli C, Di Franco M. Dietary Habits and Nutrition in Rheumatoid Arthritis: Can Diet Influence Disease Development and Clinical Manifestations? Nutrients. 2020; 12(5):1456.

Tedeschi SK, Frits M, Cui J, et al. Diet and Rheumatoid Arthritis Symptoms: Survey Results From a Rheumatoid Arthritis Registry. Arthritis Care Res (Hoboken). 2017; 69(12): 1920-1925.

Giezenaar C, Chapman I, Luscombe-Marsh N, Feinle-Bisset C, Horowitz M, Soenen S. Ageing Is Associated with Decreases in Appetite and Energy Intake-A Meta-Analysis in Healthy Adults. Nutrients. 2016; 8: 28.

Pilgrim A, Robinson S, Sayer AA, Roberts H. An overview of appetite decline in older people. Nurs. Older People. 2015; 27: 29-35.

Santilli V. Clinical definition of sarcopenia. Clin. Cases Miner. Bone Metab. 2014; 11: 177.

Rolland Y, Cesari M, Fielding RA, Reginster JY, Vellas B, Cruz-Jentoft AJ. The ICFSR Task Force. Osteoporosis in frail older adults: Recommendations for research from the ICFSR Task Force 2020. J. Frailty Aging. 2021; 10: 168-175.

Robinson S, Granic A, Sayer AA. Nutrition and muscle strength, as the key component of sarcopenia: An overview of current evidence. Nutrients. 2019; 11: 2942.

Barrere F, Van Blitterswijk CA, Groot K. Bone regeneration: Molecular and Cellular İnteractions with Calcium Phosphate Ceramics. International Journal of Nanomedicine. 2006; 1: 317-332.

Tunçay Ekin Ö. Biyomimetik yöntemle bor katkılı doku iskelelerinin geliştirilmesi ve kemik doku mühendisliğindeki etkinliklerinin araştırılması. Yüksek Lisans Tezi. Hacettepe Üniversitesi Fen Bilimleri Enstitüsü. 2013; 4-7, Ankara.

Walsh JS. Normal bone physiology, remodelling and its hormonal regulation. Surgery. 2015; 33: 1-6. https://doi.org/10.1016/j.mpsur.2014.10.010.

Bonjour J-P. Review Article Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney. Br J Nutr. 2013; 110: 1168-1177. https://doi.org/10.1017/S0007114513000962.

Wilson-Barnes SL, Susan A. Lanham-New SA, Lambert H. Modifiable risk factors for bone health & fragility fractures. Best Practice & Research Clinical Rheumatology. 2022; 36: 1-18. https://doi.org/10.1016/j.berh.2022.101758

Kini U, Nandeesh BN. Physiology of bone forma¬tion, remodeling, and metabolism. Fogelman I. et al. eds. Radionuclide and Hybrid Bone Imaging. Springer Press. Berlin-Heidelberg, 2012, p.30-55.

William OR. Functional anatomy and physiology of domestic animals. Fourth edition. 2009, p.179-198.

Buckwalter JA, Glimcher MJ, Cooper RR, Recker R. Bone biology. J Bone Joint Surg Am. 2010; 77: 1256-1275.

Hadjidakis JD, Androulakis II. Bone remodeling. Ann NY Acad Sci. 2006; 1092: 385-396.

Fradson RD, Spurgeon TL. Anatomy and Physiology of Farm Animals. Fifth edition. 1992, p. 55-81.

İnsal B, Pişkin İ. Kemik dokusunun fizyolojisi. Etlik Vet Mikrobiyol Derg. 2017; 28(1): 28-32.

Eroschenko VP. diFiore Histoloji Atlası Fonksiyonel İlişlileriyle. 10.baskı, Palme Yayınevi, Ankara. 2008.

Bassert JM, Colville T. Clinical anatomy and physi¬ology for veterinary technicians. 2002. p.95-118.

Bayliss L, Mahoney DJ, Monk P, (2012). Normal bone phys¬iology, remodeling and its hormonal regulation. Surgery. 2012; 30(2): 47-53.

Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. 2008; 3: 131-139.

Leibbrandt A, Penninger JM. RANK/RANKL: Regulators of ımmune responses and bone physiology. Ann NY Acad Sci. 2008; 1143: 123-150.

Topaloğlu U, Ketani MA, Güney Saruhan B. Kemik doku ve kemikleşme çeşitleri. Dicle Üniv Vet Fak Derg. 2017; 10(1): 62-71.

Shetty S, Kapoor N, Bondu JD, Thomas N, Paul TV. Bone turnover markers: emerging tool in the management of osteoporosis. Indian journal of endocrinology and metabolism. 2016; 20(6): 846-852.

Eastell R, Szulc P. Use of bone turnover markers in postmenopausal osteoporosis. The Lancet Diabetes and Endocrinology. 2017; 5(11): 908-923.

Kong YY, William JB, Penninger MJ. Osteoprotegerin ligand: a regulator of immune responses and bone physiology. Immunol Today. 2010; 21(10): 495-502.

Anderson JJ, Rondano P, Holmes A. Roles of diet and physical activity in the prevention of osteoporosis. Scand J Rheumatol Suppl. 1996; 103: 65-74.

Bailey DA, Martin AD, McKay HA et al. Calcium accretion in girls and boys during puberty: a longitudinal analysis. J Bone Miner Res. 2000; 15: 2245-2250.

Viljakainen HT. Factors influencing bone mass accrual: focus on nutritional aspects. Proceedings of the Nutrition Society. 2016; 75: 415-419.

Herwana E, Setiabudy R, Soegondo S, Baziad A, Hidayat A. Soy isoflavone supplementation reduces RANKL/OPG ratio on postmenopausal women with osteopenia. International Journal of Pharmaceutical Research. 2020; 12(4): 1820-1827.

Infante M, Fabi A, Cognetti F, Gorini S, Caprio M, Fabbri A. RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives. Journal of Experimental & Clinical Cancer Research. 2019; 38(1): 1-18.

Rachner TD, Kasimir-Bauer S, Göbel A, et al. Prognostic value of RANKL/OPG serum levels and disseminated tumor cells in nonmetastatic breast cancer. Clinical Cancer Research. 2019; 25(4): 136-1378.

Graham TR, Odero-Marah VA, Chung LW, Agrawal KC, Davis R, Abdel-Mageed AB. PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-κB in metastatic prostate cancer cells. The Prostate. 2009; 69(2): 168-180.

Carrillo-López N, Martínez-Arias L, Fernández-Villabrille S, et al. Role of the RANK/RANKL/OPG and Wnt/β-catenin systems in CKD bone and cardiovascular disorders. Calcified Tissue International. 2021; 108(4): 439-451.

Yari Z, Tabibi H, Najafi I, Hedayati M, Movahedian M. Effects of isoflavones on bone turnover markers in peritoneal dialysis patients: a randomized controlled trial. International Urology and Nephrology. 2020; 52(7): 1367-1376.

Sambrook P, Cooper C. Osteoporosis is a serious public health issue. The past 10 years have seen great advances in our understanding of its epidemiology, pathophysiology, and treatment, and further advances are rapidly being made. Clinical assessment will probably evolve from decisions mainly being made on the basis of bone densitometry, to use of algorithms of absolute osteoporosis. Lancet. 2006; 367(9527): 2010-2018.

Cauley JA. Estrogen and bone health in men and women. Steroids. 2015; 99: 11-15.

Graham TR, Odero-Marah VA, Chung LW, Agrawal KC, Davis R, Abdel-Mageed AB. PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-κB in metastatic prostate cancer cells. The Prostate. 2009; 69(2): 168-180.

Carrillo-López N, Martínez-Arias L, Fernández-Villabrille S, et al. Role of the RANK/RANKL/OPG and Wnt/β-catenin systems in CKD bone and cardiovascular disorders. Calcified Tissue International. 2021; 108(4): 439-451.

Brändström H, Björkman T, Ljunggren Ö. Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells. Biochemical and Biophysical Research Communications. 2001; 280(3): 831-835.

Marini H, Minutoli L, Polito F, et al. OPG and Srankl serum concentrations in osteopenic, postmenopausal women after 2-year genistein administration. Journal of Bone and Mineral Research. 2008; 23(5): 715-720.

Liu W, Zhang X. Receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin system in bone and other tissues (review). Molecular Medicine Reports. 2015; 11(5): 3212-3218.

Anderson DM, Maraskovsky E, Billingsley WL, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature. 1997; 390(6656): 17-179.

Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature. 2003; 423(6937): 337-342.

Noh D, Lim Y, Lee H, Kim H, Kwon O. Soybean-hop alleviates estrogen deficiency-related bone loss and metabolic dysfunction in ovariectomized rats fed a high-fat diet. Molecules. 2018; 23(5): 1205.

Bitto A, Burnett B, Polito F, et al. Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol. British Journal of Pharmacology. 2008; 155(6): 896-905.

Hendrickx G, Boudin E, Van Hul W. A look behind the scenes: the risk and pathogenesis of primary osteoporosis. Nat Rev Rheumatol. 2015; 11(8): 462-474. doi: 10.1038/nrrheum.2015.48.

Kanis JA, McCloskey EV, Johansson H, Oden A, Melton LJ. Khaltaev N. A reference standard for the description of osteoporosis. Bone. 2008; 42(3): 467-475. doi:10.1016/j.bone.2007.11.001.

Cosman F, de Beur SJ, LeBoff MS, et al. Clinician's guide to prevention and treatment of osteoporosis: A journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. Osteoporos Int. 2014; 25: 2359-2381. https://doi.org/10.1007/s00198-014-2794-2.

Papadopoulou SK, Papadimitriou K, Voulgaridou G, Georgaki E, Tsotidou E, Zantidou O, Papandreou D. Exercise and nutrition impact on osteoporosis and sarcopenia-The incidence of osteosarcopenia: A narrative review. Nutrients. 2021; 13: 1-14. https://doi.org/10.3390/nu13124499.

Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006; 17: 1726-1733.

Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, Muratore M, Casciaro S. Major osteoporotic fragility fractures: Risk factor updates and societal impact. World J. Orthop. 2016; 7: 171-181.

Gao Y, Patil S, Jia J. The development of molecular biology of osteoporosis. Int. J. Mol. Sci. 2021; 22: 8182.

Dhillon RJ, Hasni S. Pathogenesis and management of sarcopenia. Clin. Geriatr. Med. 2017; 33: 17-26.

Hunter GR, Singh H, Carter SJ, Bryan DR, Fisher G. Sarcopenia and its implications for Metabolic Health. J. Obes. 2019; 2019: 8031705.

Aaseth J, Boivin G, Andersen O. Osteoporosis and trace elements–an overview. J Trace Elem Med Biol. 2012; 26(2-3):149-152. doi: 10.1016/j.jtemb.2012.03.017

Ratajczak AE, Rychter AM, Zawada A, Dobrowolska A, Krela-Kazmierczak I. Do only calcium and vitamin D matter? Micronutrients in the diet of inflammatory bowel diseases patients and the risk of osteoporosis. Nutrients. 2021; 13(2): 525. doi: 10.3390/nu13020525

Zhang H, Wang A, Shen G, Wang X, Liu G, Yang F, et al. Hepcidin-induced reduction in iron content and PGC-1beta expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis. Aging (Albany NY). 2021; 13(8): 11296-11314. doi: 10.18632/aging.202817

Ceylan MN, Akdas S, Yazihan N. Is zinc an important trace element on bonerelated diseases and complications? A meta-analysis and systematic review from serum level, dietary intake, and supplementation aspects. Biol Trace Elem Res. 2021; 199(2): 535-549. doi: 10.1007/s12011-020-02193-w

Föger-Samwald U, Dovjak P, Azizi-Semrad U, Kerschan-Schindl K, Pietschmann P. Osteoporosis: Pathophysiology and therapeutic options. EXCLI J. 2020; 19: 1017-1037.

Mankin HJ, Radin EL. Structure and Function of Joints. D. J. McCary ve W. J. Kopman (Ed.). Arthritis and Allied Conditions: A Textbook of Rheumatolog. Philadelphia: Lea&Febige.1993. s:181-197.

Rogers J. The Paleopathology of Joint Disease. M. Cox ve S. Mays (Ed.). Human Osteology in Archaeology an Forensic Science. London: Greenwich Medical Media Ltd.2000. s.163-182.

Doherty M, Jones A, Cawston TE. Osteoarthritis In: Textbook of Rheumatology, Madison PJ, Isenberg DA, Woo P, Glass DN, editors. Oxford University Pres; 1998. s.1515-1553.

Savcı A, Bilik Ö. Ortopedi ve Travmatoloji Kliniğinde Geriatrik Değerlendirme. Deuhyo Ed. 2014; 7: 156-163.

Erdal ÖD. Eklem hastalıkları ve yaşam biçimi arasındaki ilişkiler: Anadolu neolitik topluluklarından örnekler. Edebiyat Fakültesi Dergisi. 2007; 24(2): 77-93.

Altındağ Ö, Sırmatel Ö, Tabur H. Diz osteoartriti olan hastalarda demografik özellikler ve klinik parametrelerle ilişkisi. Harran Üniversitesi Tıp Fakültesi Dergisi. 2006; 3: 62-66.

Roos EM, Arden NK. Strategies for the prevention of knee osteoarthritis. Nat Rev Rheumatol. 2016; 12(2): 92-101.

Göğüş F. Osteoartroz. In: Yazıcı H, Hamuryudan V, Sonsuz A, Ed. İç Hastalıkları. 1. Baskı. İstanbul: İstanbul Medikal Yayıncılık. İstanbul. 2005. p.1012-1015.

Hizmetli S, Tel H, Tel H, Yıldırım M. Self-care agency and status to maintain activities of daily living elderly people with osteoarthritis. Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi 2012; 15: 27-32.

Scrivo R, Vasile M, Müller-Ladner U, Neumann E, Valesini G. Rheumatic diseases and obesity: adipocytokines as potential comorbidity biomarkers for cardiovascular diseases. Mediators of inflammation. 2013; 2013.

Kulkarni K, Karssiens T, Kumar V, Pandit H. Obesity and osteoarthritis. Maturitas. 2016; 89: 22-28.

Arden NK, Perry TA, Bannuru RR, Bruyère O, Cooper C, Haugen IK, et al. Non-surgical management of knee osteoarthritis: Comparison of ESCEO and OARSI 2019 guidelines. Nat Rev Rheumatol. 2021; 17(1): 59-66.

Lespasio MJ, Piuzzi NS, Husni ME, Muschler GF, Guarino AJ, Mont MA. Knee osteoarthritis: a primer. Perm J. 2017; 21: 16-183.

Morris JL, Letson HL, Gillman R, Hazratwala K, Wilkinson M, McEwen P, et al. The CNS theory of osteoarthritis: opportunities beyond the joint. Semin Arthritis Rheum. 2019; 49(3): 331-336.

Sun X, Zhen X, Hu X, Li Y, Gu S, Gu Y, Dong H. Osteoarthritis in the middle-aged and elderly in China: prevalence and influencing factors. Int J Environ Res Public Health. 2019; 16(23): 4701.

Cope PJ, Ourradi K, Li Y, Sharif M. Models of osteoarthritis: the good, the bad and the promising. Osteoarthritis Cartilage. 2019; 27(2): 230-9.

Karataş T, Yılmaz E, Polat Ü. Osteoartrit yönetimi, yaşam kalitesi ve hemşirenin destekleyici rolü. SDÜ Tıp Fak Derg. 2022: 29(2): 265-271, doi: 10.17343/sdutfd.1017250

Marcora S, Lemmey AB, Maddison PJ. Dietary treatment of rheumatoid cachexia with beta-hydroxy-betamethylbutyrate, glutamine and arginine: a randomised controlled trial. Clin Nutr. 2005; 24(3): 442–454.

Gómez-Vaquero C, Nolla JM, Fiter J, Ramon JM, Concustell R, Valverde J, et al. Nutritional status in rheumatoid arthritis. Joint Bone Spine. 2001; 68(5): 403-409.

Grassi W, De Angelis R, Lamanna G, et al. The clinical features of rheumatoid arthritis. European Journal of Radiology. 1998; 27: 18-24.

Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. Lancet. 2010; 376: 1094-1108.

Kitas GD, Gabriel SE. Cardiovascular disease in rheumatoid arthritis: state of the art and future perspectives. Annals of the rheumatic diseases. 2011; 70(1): 8-14.

Bustamante MF, Agustín-Perez M, Cedola F, et al. Design of an anti-inflammatory diet (ITIS diet) for patients with rheumatoid arthritis. Contemporary clinical trials communications. 2020; 17: 100524.

Oğur H, Günaydın R, Rakıcıoğlu N. Romatoid artritli kadın hastalarda beslenme durumunun değerlendirilmesi. Bes Diy Derg. 2020; 48(1): 63-72.

Zhen H, Gui F. The role of hyperuricemia on vascular endothelium dysfunction. Biomedical Reports. 2017; 7(4): 325-330.

Hirschfeld Hp, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017; 28(10): 2781-2790.

Kirk B, Al Saedi A, Duque G. Osteosarcopenia: a case of geroscience. Aging Med (Milton). 2019; 2(3): 147-156.

Kutsal YG, Özdemir O, Sarıdoğan FM, Günendi Z, Küçükdeveci AA, Kirazlı Y, et al. Osteosarkopeni: Klinik perspektif. Turk j Osteoporos. 2020; 26(2): 47-57.

Can B, Şanlıer N. Osteosarkopenide Beslenme Yaklaşımları: Geleneksel Derleme. Türkiye Klinikleri J Health Sci. 2022; 7(4): 1216-1225.

Harris SS, Dowson-Hudges B. Weight, body composition and bone density in postmenopausal women. Calcif Tissue Int. 1996; 59: 428-432.

Manzoni P, Brambilla P, Pietrobelli A, Beccaria L, Bianchessi A, Mora S, Chiumello G. Influence of body composition on bone mineral content in children and adolescents. Am J Clin Nutr. 1996; 64: 603-607.

Milos G, Moergeli H, Sob C, et al. Positive effect of Teriparatide on areal bone mineral density in young women with anorexia nervosa: a pilot study. Calcif Tissue Int. 2021; 108: 595-604. https://doi.org/10.1007/S00223-020-00791-3.

Park JH, Song YM, Sung J, Lee K, Kim YS, Kim T, et al. The association between fat and lean mass and bone mineral density: The Healthy Twin Study. Bone. 2012; 50: 1006-1011.

Yoo HJ, Park MS, Yang SJ, Kim TN, Lim K Il, Kang HJ, et al. The differential relationship between fat mass and bone mineral density by gender and menopausal status. J Bone Miner Metab. 2012; 30: 47-53.

Hu WW, Zhang H, Wang C, Gu JM, Yue H, Ke YH, et al. Lean mass predicts hip geometry and bone mineral density in Chinese men and women and age comparisons of body composition. J Clin Densitom 2012;15:434-42.

Kılınçarslan MG, Şahin EM, Sarıgül B, Kocaoğlu SB. Postmenopozal Türk Kadınlarında Vücut Kompozisyonu ve Fiziksel Aktivitenin Kemik Mineral Yoğunluğu ile İlişkisi. Turk J Osteoporos. 2020; 26: 70-74.

Liu Y, Xu Y, Wen Y, Guan K, Ling W, He L, et al. Association of weight-adjusted body fat and fat distribution with bone mineral density in middle-aged Chinese adults: A cross-sectional study. PLoS One 2013;8:e63339.

Chain A, Crivelli M, Faerstein E, Bezerra FF. Association between fat mass and bone mineral density among Brazilian women differs by menopausal status: The Pró-Saúde Study. Nutrition 2017;33:14-9.

Ho-Pham LT, Nguyen UDT, Nguyen TV. Association between lean mass, fat mass, and bone mineral density: A Meta-analysis. J Clin Endocrinol Metab. 2014; 99: 30-38.

Gümüş K, Ünsal A. Osteoartritli bireylerin günlük yaşam aktivitelerinin değerlendirilmesi. Türk Osteoporoz Dergisi. 2014; 20: 117-124.

Koçak B, Yüksel A. Kemik-eklem hastalıklarının obezite ile ilişkisi. Sağlık ve Yaşam Bilimleri Dergisi. 2021. 3(1): 97-100. doi: 10.33308/2687248X.202131205.

Ilich JZ, BrownbilI RA, Tamborini L: Bone and nutrition in elderly vvomen: protein, energy, and calcium as main determinants of bone mineral density. European Journal of Clinical Nutrition. 2003; 57: 554-565.

Sarıbay GF, Başaran A, Akın S, Korkusuz F. Beslenme ve kemik mineral yoğunluğu ilişkisi. Beslenme ve Diyet Dergisi. 2005; 33(2): 57-69.

Cloutier GR, Barr SI. Protein and bone health: Literature review and counseling implications. Canadian Journal of Dietetic Practice and Research. 2003; 64: 5-11.

Massey LK. Dietary animal and plant protein and human bone health: A whole foods approach. Journal of Nutrition. 2003; 133: 862-865.

Skov AR, Haulrik N, Toubro S, Molgaard C, Astrup A: Effect of protein intake on bone mineralization during weight loss: A 6 -month trial. Obesity Research. 2002;10: 432-438.

Bunker VW. The role o f nutrition in osteoporosis. British Journal of Biomedical Science. 1994;51: 228-240.

Rapuri PB, Gallagher JC, Haynatzka V. Protein intake: effects on bone mineral density and the rate of bone loss in elderly women. American Journal o f Clinical Nutrition. 2003; 77: 1517-1525.

Wohl GR, Loehrke L, VVatkins BA, Zernicke RF. Effects of high-fat diet on mature bone mineral content, structure, and mechanical properties. Calcified Tissue International. 1998; 63: 74-79.

Rigotti NA, Nussbaum SR, Herzog DB, Neer RM. Osteoporosis in women with anorexia nervosa. N Engl J Med. 1984; 311: 1601-1606. https://doi.org/ 10.1056/ NEJM198412203112503.

Zipfel S, Seibel MJ, Lowe B, et al. Osteoporosis in eating disorders: a follow-up study of patients with anorexia and bulimia nervosa. J Clin Endocrinol Metab. 2001; 86: 5227-5233. https://doi.org/10.1210/JCEM.86.11.8050.

Legroux I, Cortet B. Factors influencing bone loss in anorexia nervosa: assessment and therapeutic options. RMD Open. 2019; 5: 001009. https://doi.org/10.1136/RMDOPEN-2019-001009.

Micali N, Martini MG, Thomas JJ, et al. Lifetime and 12-month prevalence of eating disorders amongst women in mid-life: a population-based study of diagnoses and risk factors. BMC Med 2017; 15. https://doi.org/10.1186/S12916-016-0766-4.

Plasqui G. The role of physical activity in rheumatoid arthritis. Physiol Behav. 2008; 94(2): 270-275.

Elma Ö, Tümkaya Yilmaz S, Deliens T, Coppieters I, Clarys P, Nijs J, et al. Do nutritional factors interact with chronic musculoskeletal pain? A systematic review. J Clin Med. 2020; 9(3): 702.

Kutsal YG, Özdemir O, Sarıdoğan FM, Günendi Z, Küçükdeveci AA, Kirazlı Y, et al. Osteosarkopeni: Klinik perspektif. Turk j Osteoporos. 2020; 26(2): 47-57.

Marzetti E, Calvani R, Tosato M, Cesari M, Di Bari M, Cherubini a, et al; SPRINTT Consortium. Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging Clin Exp Res. 2017; 29(1): 35-42.

Kirk B, Zanker J, Duque G. Osteosarcopenia: epidemiology, diagnosis, and treatment-facts and numbers. J Cachexia sarcopenia Muscle. 2020; 11(3): 609-618.

Ilich JZ, Kelly OJ, Kim Y, Spicer MT. Low-grade chronic inflammation perpetuated by modern diet as a promoter of obesity and osteoporosis. Arh Hig Rada Toksikol. 2014; 65(2): 139-148.

Chew J, Yeo A, Yew S, Tan CN, Lim JP, Hafizah Ismail N, et al. Nutrition mediates the relationship between osteosarcopenia and frailty: a pathway analysis. Nutrients. 2020; 12(10): 2957.

Logue DM, Madigan SM, Melin A, et al. Low energy availability in athletes 2020: An updated narrative review of prevalence, risk, within-day energy balance, knowledge, and impact on sports performance. Nutrients. 2020;12. https://doi.org/10.3390/NU12030835.

Mountjoy M, Sundgot-Borgen JK, Burke LM, et al. IOC consensus statement on relative energy deficiency in sport (RED-S): 2018 update. Br J Sports Med. 2018; 52: 687-697. https://doi.org/10.1136/bjsports-2018-099193.

Carruth BR and Skinner JD: Dietary intake of females recovered from disordered eating. Journal of the Amcrican Dietctic Association. 1997; 97: A17.

Sarazin M, Alexandre C, Thomas T. Influence on bone metabolism of dietary trace elements, protein, fat, carbohydrates, and vitamins. Joint Bone Spine. 2000; 67: 408-418.

Trichopoulou A, Georgiou E, Bassiakos Y, Lipworth L, Lagiou P, Proukakis C, Trichopoulos D: Energy intake and monounsaturated fat in relation to bone mineral density among women and men in Greece. Preventive Medicine. 1997; 26: 395-400.

He J, Wang Y, Feng M, et al. Dietary intake and risk of rheumatoid arthritis-a cross section multicenter study. Clin Rheumatol. 2016; 35(12) :2901-2908.

Rondanelli M, Perdoni F, Peroni G, Caporali R, Gasparri C, Riva A, et al. Ideal food pyramid for patients with rheumatoid arthritis: A narrative review. Clin Nutr. 2021; 40(3):661-689.

Darling AL, Manders RJF, Sahni S, et al. Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years. Osteoporos Int 2019; 30: 741-761. https://doi.org/10.1007/s00198-019-04933-8.

Papageorgiou M, Dolan E, Elliott-Sale KJ, Sale C. Reduced energy availability: implications for bone health in physically active populations. Eur J Nutr. 2018;57:847e59. https://doi.org/10.1007/s00394-017-1498-8.

Frassetto L, Banerjee T, Powe N, Sebastian A. Acid balance, dietary acid load, and bone effects-A controversial subject. Nutrients. 2018; 10: 517. https://doi.org/10.3390/nu10040517.

Galchenko A, Gapparova K, Sidorova E. The influence of vegetarian and vegan diets on the state of bone mineral density in humans. Crit Rev Food Sci Nutr. 2021;1-17. https://doi.org/10.1080/10408398.2021.1996330.

Yoo JI, Lee KH, Choi Y, Lee J, Park YG. Poor dietary protein intake in elderly population with sarcopenia and osteosarcopenia: a nationwide population-based study. J Bone Metab. 2020; 27(4): 301-310.

Berner La, Becker g, Wise M, Doi j. Characterization of dietary protein among older adults in the United states: amount, animal sources, and meal patterns. j acad Nutr Diet. 2013;113(6):809-15.

Granic A, Mendonça N, Sayer AA, Hill TR, Davies K, Siervo M, et al. Effects of dietary patterns and low protein intake on sarcopenia risk in the very old: the Newcastle 85+ study. Clin Nutr. 2020; 39(1): 166-173.

Kaner G, Çalık G, Eren E, Gerdan V. Romatoid artritte tıbbi beslenme tedavisine yönelik yaklaşımlar. Bes Diy Derg. 2021; 49(1): 75-81.

Çalık, Y, Yazıcı S, Baş E, Ataoğlu S. Postmenopozal kadınlarda lipid düzeyleri ve kemik mineral yoğunluğu arasındaki ilişki. Düzce Tıp dergisi. 2010; 12(2): 30-35.

Diascro Jr DD, Vogel RL, Johnson TE, Witherup KM, Pitzenberger SM, Rutledge SJ, Prescott DJ, Rodan GA, Schmidt A: High fatty acid content in rabbit serum is responsible fort he differentiation of the osteoblasts into adipocyte-like cells. J Bone Miner Res.1998;13: 96-106.

Demer LL, Perhami F. Arterial calcification in face of osteoporosis in aging: can web lame oxidized lipids? Curr Opin Lipidol. 1997; 8: 312-314.

Parhami F, Garfinkel A, Demer LL: Role of lipids in osteoporosis. Arterioscler Thromb Vasc Biol. 2000; 20: 2346-2348.

Cerrahoğlu L, Duruöz MT, Şenocak İ: Postmenopozal osteoporozda yüksek kolesterol düzeyi ile kemik mineral yoğunluğunun ilişkisi. Türk Fiz Reh Dergisi. 2000;12: 23-27.

Yamaguchi T, Sugimoto T, Yamauchi M, Sowa H, Chen Q, Chihara K. Plasma lipids and osteoporosis in postmenopausal women. Endocr J. 2002; 49: 211–217.

Solomon DH, Avorn J, Canning CF, Wang PS: Lipids levels and bone mineral density. The American Journal of Medicine. 2002; 118: 1414-1418.

Linos A, Kaklamani V, Kaklamani E, Koumantaki Y, GiziakiE, Papazoglou S, et al. Dietary factors in relation to rheumatoid arthritis: a role for olive oil and cooked vegetables? Am J Clin Nutr. 1999; 70: 1077-1082.

Gioia C, Lucchino B, Tarsitano MG, Iannuccelli C, Di Franco M. Dietary habits and nutrition in rheumatoid arthritis: Can diet influence disease development and clinical manifestations? Nutrients. 2020; 12(5): 1456.

Lavado-Garcia JM, Roncero-Martin R, Moran JM, Pedrera-Canal M, Aliaga I, Leal-Hernández O, Martin, S.R, Canal-Macias ML. Long-chain omega-3 polyunsaturated fatty acid dietary intake is positively associated with bone mineral density in normal and osteopenic Spanish women. PLoS ONE. 2018; 13: 0190539.

Roncero-Martín R, Aliaga I, Moran J, Puerto-Parejo L, Rey-Sánchez P, de la Luz Canal-Macías M, Sánchez-Fernández A, Pedrera-Zamorano J, López-Espuela F, Vera V, et al. Plasma fatty acids and quantitative ultrasound, DXA and pQCT derived parameters in postmenopausal Spanish women. Nutrients. 2021; 13: 1454.

Shen D, Zhang X, Li Z, Bai H, Chen L. Effects of omega-3 fatty acids on bone turnover markers in postmenopausal women: systematic review and meta-analysis. Climacteric. 2017; 20(6): 522-527.

Gómez EF, Kaufer-Horwitz M, Mancera-Chávez GE. Medical Nutrition Therapy for Rheumatic Disease. In: Mahan KL, Raymond JL, editors. Krause’s Food & The Nutrition Care Process-E Book. 14th ed. Kanada: Elsevier Health Sciences; p.2017.

Cruz-jentoft AJ, Landi F, Schneider SM, Zú-Iga C, Arai H, Boirie Y, et al. Prevalence of and interventions for sarcopenia in ageing adults: A systematic review. Report of the International sarcopenia Initiative (EWgsOp and IWgs). Age Ageing. 2014; 43(6): 748-759.

Fonolla-Joya J, Reyes-García R, García-Martín A, López-Huertas E, Muoz-Torres M. Daily intake of milk enriched with n-3 fatty acids, oleic acid, and calcium improves metabolic and bone biomarkers in postmenopausal women. J Am Coll Nutr. 2016; 35(6): 529-536.

Sadeghi O, Djafarian K, Ghorabi S, Khodadost M, Nasiri M, Shab-Bidars. Dietary intake of fish, n-3 polyunsaturated fatty acids and risk of hip fracture: A systematic review and meta-analysis on observational studies. Crit Rev Food Sci Nutr. 2019; 59(8): 1320-1333.

Aaseth J, Boivin G, Andersen O. Osteoporosis and trace elements-an overview. J. Trace. Elem. Med. Biol. 2012; 26: 149-152.

Tessier AJ, Chevalier S. An update on protein, leucine, omega-3 fatty acids, and vitamin D in the prevention and treatment of sarcopenia and functional decline. Nutrients. 2018; 10(8): 1099.

Makida K, Nishida Y, Morita D, Ochiai S, Higuchi Y, Seki T, et al. Low energy irradiation of narrow-range UV-LED prevents osteosarcopenia associated with vitamin D deficiency in senescence accelerated Mouse prone 6. Sci Rep. 2020; 10(1): 11892.

Abidin NZ, Mitra SR. Total VS. Bioavailable: determining a better 25(OH)D index in association with bone density and muscle mass in postmenopausal women. Metabolites. 2020; 11(1): 23.

Hirschfeld HP, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017; 28(10): 2781-2790.

LeBoff M, Greenspan S, Insogna K, et al. The clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 2022. https://doi.org/10.1007/S00198-021-05900-Y

Reid IR, Bolland MJ, Grey A. Effects of vitamin D supplements on bone mineral density: A systematic review and meta-analysis. Lancet. 2014; 383: 146-155. https://doi.org/10.1016/S0140-6736(13)61647-5

Khaw K, Stewart A, Waayer D, et al. Effect of monthly high-dose vitamin D supplementation on falls and non-vertebral fractures: secondary and post-hoc outcomes from the randomised, double-blind, placebo-controlled ViDA trial. Lancet Diabetes Endocrinol. 2017; 5(8): 438-447. https://doi.org/10.1016/S2213-8587(17)30103-1

Manios Y, Moschonis G, Mavrogianni C, van den Heuvel E, Singh-Povel CM, Kiely M, Cashman KD. Reduced-fat Gouda-type cheese enriched with vitamin D3 effectively prevents vitamin D deficiency during winter months in postmenopausal women in Greece. Eur. J. Nutr. 2017; 56: 2367-2377.

Moran JM. Nutrition and Women’s Bone Health. Nutrients. 2022; 14: 763. https://doi. org/10.3390/nu14040763

Sharma J, Heagerty R. Stress fracture: A review of the pathophysiology, epidemiology and management options. J Fract Sprains. 2017. Available: https://www. researchgate.Net/ publication/320719800

Silk LN, Greene DA, Baker MK. The effect of calcium or calcium and vitamin D supplementation on bone mineral density in healthy males: a systematic review and meta-analysis. Int J Sport Nutr Exerc Metabol. 2015; 25: 510-524. https://doi. org/ 10. 1123/ ijsnem. 2014-0202

Wilson G, FraserW, Sharma A, et al. Markers of bone health, renal function, liver function, anthropometry and perception of mood: a comparison between flat and national hunt Jockeys. Int J Sports Med. 2012; 34: 453-459. https://doi.org/10.1055/s-0032-1321898

Vallibhakara, S.A.-O, Nakpalat K, Sophonsritsuk A, Tantitham C, Vallibhakara O. Effect of vitamin e supplement on bone turnover markers in postmenopausal osteopenicwomen: A double-blind, randomized, placebo-controlled trial. Nutrients. 2021; 13: 4226.

Kim D, Han A, Park Y. Association of dietary total antioxidant capacity with bone mass and osteoporosis risk in korean women: analysis of the korea national health and nutrition examination survey 2008-2011. Nutrients. 2021; 13: 1149.

Aksu M, Yöney B. Romatoid artrite güncel beslenme yaklaşımları. Current Perspectives on Health Sciences. 2023; 4(3): 96-103.

Cutolo M, Otsa K, Uprus M, Paolino S, Seriolo B. Vitamin D in rheumatoid arthritis. Autoimmun Rev. 2007; 7(1): 59-64.

Meena N, Singh Chawla SP, Garg R, Batta A, Kaur S. Assessment of vitamin d in rheumatoid arthritis and ıts correlation with disease activity. J Nat Sci Biol Med. 2018; 9(1): 54-58.

Harrison SR, Li D, Jeffery LE, Raza K, Hewison M. Vitamin D, autoimmune disease and rheumatoid arthritis. Calcif Tissue Int. 2020; 106(1): 58-75.

Holick MF. Resurrection of vitamin D deficiency and rickets. J Clin Investig. 2006; 116: 2062-2072. https://doi.org/10.1172/JCI29449.

Yabancı N, Pekcan G. Adolesanlarda beslenme durumu ile fiziksel aktivite düzeyinin vücut bileşimi ve kemik mineral yoğunluğu üzerine etkisi. Aile ve Toplum. 2010; 11(6): -20.

Massey LK, Hollingbery PW. Acute effects of dietary caffeine and sucrose on urinary mineral excretion of healthy adolescents. Nutr Res. 1998; 8: 1005.

Hoover PA, Wabber CE, Beaumont LF, and Blake JM. Postmenopausal bone mineral density: Relationship to calcium intake, calcium absorption, residual estrogen, body composition and physical activity. Can J Physiol Pharmacol. 1996; 74: 911-917.

Marusic A, Kos K, Stavljenic A, Vukicevic S. Acute zinc deficiency and trabecular bone loss in rats with talc granulomatosis. Nutr Abs Rev. 1993; 63(4): 338.

Specker BL. Evidence for an interaction between calcium intake and physical activity on changes in bone mineral density. J Bone Miner Res. 2009; 11: 1539-1544. https://doi. org/ 10.1002/jbmr.5650111022.

Green JH, Booth C, Bunning R. Acute effect of high-calcium milk with or without additional magnesium, or calcium phosphate on parathyroid hormone and biochemical markers of bone resorption. Eur J Clin Nutr. 2003; 57: 61-68. https://doi.org/ 10.1038/sj.ejcn. 1601501.

Cadogan J, Eastell R, Jones N, Barker ME. Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial. BMJ (Clinical research ed). 1997; 315: 1255-1260. https://doi.org/10.1136/BMJ.315.7118.1255.

Lambert HL, Eastell R, Karnik K, et al. Calcium supplementation and bone mineral accretion in adolescent girls: an 18-month randomized controlled trial with 2-y follow-up. Am J Clin Nutr. 2008; 87: 455-462. https://doi.org/10.1093/AJCN/87.2.455.

Aloia J, Bojadzievski T, Yusupov E, et al. The relative influence of calcium intake and vitamin D status on serum parathyroid hormone and bone turnover biomarkers in a double-blind, placebo-controlled parallel group, longitudinal factorial design. J Clin Endocrinol Metabol. 2010; 95: 3216-3224. https://doi.org/10.1210/jc.2009-1294.

Kanadys W, Barańska A, Błaszczuk A, et al. Effects of soy isoflavones on biochemical markers of bone metabolism in postmenopausal women: a systematic review and metaanalysis of randomized controlled trials. International Journal of Environmental Research and Public Health. 2021; 18(10): 5346.

Herwana E, Setiabudy R, Soegondo S, Baziad A, Hidayat A. Soy isoflavone supplementation reduces RANKL/OPG ratio on postmenopausal women with osteopenia. International Journal of Pharmaceutical Research. 2020; 12(4): 1820-1827.

Lv Z, Yan S, Li G, Liu D, Guo Y. Genistein improves the reproductive performance and bone status of breeder hens during the late egg-laying period. Poultry Science. 2019, 98(12): 7022-7029.

Nakai S, Fujita M, Kamei Y. Health promotion effects of soy isoflavones. Journal of Nutritional Science and Vitaminology. 2020; 66(6): 502-507.

Scheiber MD, Liu JH, Subbiah M, Rebar RW, Setchell KD. Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women. Menopause. 2001; 8(5): 384-392.

Liu W, Zhang X. Receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin system in bone and other tissues (review). Molecular Medicine Reports. 2015; 11(5): 3212-3218.

Hooshiar SH, Tobeiha M, Jafarnejad S. Soy Isoflavones and Bone Health: Focus on the RANKL/RANK/OPG Pathway. BioMed Research International. 2022; 1-10. https://doi.org/10.1155/2022/8862278

Nayeem F, Chen N-W, Nagamani M, Anderson KE, Lu LJ-W. Daidzein and genistein have differential effects in decreasing whole body bone mineral density but had no effect on hip and spine density in premenopausal women: a 2-year randomized, double-blind, placebo-controlled study. Nutrition Research. 2019; 68: 70-81.

Chen W-F, Wong M-S. Genistein modulates the effects of parathyroid hormone in human osteoblastic SaOS-2 cells. British Journal of Nutrition. 2006; 95(6): 1039-1047.

Tit DM, Bungau S, Iovan C, et al. Effects of the hormone replacement therapy and of soy isoflavones on bone resorption in postmenopause. Journal of Clinical Medicine. 2018; 7(10): 297.

Santos M, Florencio-Silva R, Medeiros V. et al. Effects of different doses of soy isoflavones on bone tissue of ovariectomized rats. Climacteric. 2014; 17(4): 393-401.

Lanham-New SA, Lambert H, Frassetto L. Potassium. Advances in Nutrition. 2012; 3: 820. https://doi.org/10.3945/AN.112.003012.

Martiniakova M, Babikova M, Mondockova V, et al. The role of macronutrients, micronutrients and flavonoid polyphenols in the prevention and treatment of osteoporosis. Nutrients. 2022; 14. https://doi.org/10.3390/NU14030523.

Nieves JW. Osteoporosis: The role of micronutrients. Am J Clin Nutr. 2005; 81. https://doi.org/10.1093/AJCN/81.5.1232.

Pietschmann N, Rijntjes E, Hoeg A, Stoedter M, Schweizer U, Seemann P, et al. Selenoprotein P is the essential selenium transporter for bones. Metallomics. 2014; 6(5): 1043–9. doi: 10.1039/C4MT00003J

Manolagas SC. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev. 2010, 31(3): 266-300. doi: 10.1210/er.2009-0024

Zhou H, Wang T, Li Q, Li D. Prevention of keshan disease by selenium supplementation: a systematic review and meta-analysis. Biol Trace Elem Res. 2018; 186(1): 98-105. doi: 10.1007/s12011-018-1302-5.

Winther KH, Rayman MP, Bonnema SJ, Hegedus L. Selenium in thyroid disorders - essential knowledge for clinicians. Nat Rev Endocrinol. 2020; 16(3): 165-76. doi: 10.1038/ s41574-019-0311-6

Galvez-Fernandez M, Grau-Perez M, Garcia-Barrera T, Ramirez-Acosta S, Gomez-Ariza JL, Perez-Gomez B, et al. Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The HORTEGA study. Free Radic Biol Med. 2021; 162: 392-400. doi: 10.1016/j.freeradbiomed.2020.10.318

Wang Y, Xie D, Li J, Long H, Wu J, Wu Z, et al. Association between dietary selenium intake and the prevalence of osteoporosis: A cross-sectional study. BMC Musculoskelet Disord. 2019; 20(1): 585. doi: 10.1186/s12891-019-2958-5

Xue G, Liu R. Association between dietary selenium intake and bone mineral density in the US general population. Ann Transl Med. 2022; 10(16): 869. doi:10.21037/atm-22-3441

Peng S, Zhang G, Wang D. Association of selenium intake with bone mineral density and osteoporosis. The national health and nutrition examination survey. Frontiers in Endocrinology. 2023. 1-11. Doi. 10.3389/fendo.2023.1251838

Wolf RL, Cauley JA, Pettinger M, Jackson R, Lacroix A, Leboff MS, et al. Lack of a relation between vitamin and mineral antioxidants and bone mineral density: results from the Women’s Health Initiative. Am J Clin Nutr. 2005; 82(3): 581-588. doi: 10.1093/ajcn/82.3.581

Walsh JS, Jacques RM, Schomburg L, Hill TR, Mathers JC, Williams GR, et al. Effect of selenium supplementation on musculoskeletal health in older women: a randomised, double-blind, placebo-controlled trial. Lancet Healthy Longev. 2021; 2(4): 212-221. doi: 10. 1016/S2666-7568(21)00051-9

Xie H, Wang N, He H, Yang Z, Wu J, Yang T, et al. The association between selenium and bone health: a meta-analysis. Bone Joint Res. 2023; 12(7): 423-432. doi: 10. 1302/2046-3758.127.BJR-2022-0420.R1

Zhang J, Munger RG, West NA, Cutler DR, Wengreen HJ, Corcoran CD. Antioxidant intake and risk of osteoporotic hip fracture in Utah: an effect modified by smoking status. Am J Epidemiol. 2006; 163(1): 9-17. doi: 10.1093/aje/kwj005

Hardcastle AC, Aucott L, Fraser WD, et al. Dietary patterns, bone resorption and bone mineral density in early postmenopausal Scottish women. Eur J Clin Nutr. 2011; 65: 378-385. https://doi.org/10.1038/ejcn.2010.264.

Gannon RHT, Millward DJ, Brown JE, et al. Estimates of daily net endogenous acid production in the elderly UK population: Analysis of the National Diet and Nutrition Survey (NDNS) of British adults aged 65 years and over. 2019. https:// doi.org/ 10. 1017/ S0007114508901240.

Gioia C, Lucchino B, Tarsitano MG, Iannuccelli C, Di Franco M. Dietary Habits and Nutrition in Rheumatoid Arthritis: Can Diet Influence Disease Development and Clinical Manifestations? Nutrients. 2020; 12(5):1456.

Tedeschi SK, Frits M, Cui J, et al. Diet and Rheumatoid Arthritis Symptoms: Survey Results From a Rheumatoid Arthritis Registry. Arthritis Care Res (Hoboken). 2017; 69(12): 1920-1925.

Giezenaar C, Chapman I, Luscombe-Marsh N, Feinle-Bisset C, Horowitz M, Soenen S. Ageing Is Associated with Decreases in Appetite and Energy Intake-A Meta-Analysis in Healthy Adults. Nutrients. 2016; 8: 28.

Pilgrim A, Robinson S, Sayer AA, Roberts H. An overview of appetite decline in older people. Nurs. Older People. 2015; 27: 29-35.

Santilli V. Clinical definition of sarcopenia. Clin. Cases Miner. Bone Metab. 2014; 11: 177.

Rolland Y, Cesari M, Fielding RA, Reginster JY, Vellas B, Cruz-Jentoft AJ. The ICFSR Task Force. Osteoporosis in frail older adults: Recommendations for research from the ICFSR Task Force 2020. J. Frailty Aging. 2021; 10: 168-175.

Robinson S, Granic A, Sayer AA. Nutrition and muscle strength, as the key component of sarcopenia: An overview of current evidence. Nutrients. 2019; 11: 2942.