Omurilik (Omurga) ve Beyne Metastaz Yapan Nüks İntrakraniyal Hemanjiyoperisitoma: Vaka Sunumu
Özet
Hemanjiyoperisitomlar, kapillerleri çevreleyen ve Zimmerman perisitleri olarak bilinen kontraktil hücrelerden türeyen nadir, vasküler tümörlerdir. Yüksek nüks ve metastaz eğilimi gösteren oldukça agresif meningeal tümörlerdir. Çoğu meningeal hemanjiyoperisitom makroskopik olarak menenjiomlara benzer, ancak farklı histolojik özellikler gösterir. Önceki çalışmalarda, hemanjiyoperisitomlar menenjiomların anjioblastik bir varyantı olarak sınıflandırılmıştı, ancak daha sonra klinik ve histolojik olarak farklı antiteler olarak tanımlandılar. Hemanjiyoperisitomları menenjiomlardan ayırt etmek önemlidir, çünkü agresif yapıları nedeniyle farklı bir tedavi yaklaşımı gerektirirler. Bu çalışmada, omurga ve beyne metastaz yapan nadir bir nüks etmiş intrakraniyal hemanjiyoperisitom vakasını sunuyoruz.
Hemangiopericytomas are rare, vascular tumors derived from pericytes which are the contractile cells surrounding capillaries and are known as Zimmerman pericytes. They are highly aggressive meningeal tumors with a tendency for high recurrence and metastases.
Most meningeal hemangiopericytomas resemble meningiomas macroscopically, but with distinct histology. In previous studies, hemangiopericytomas were classified as an angioblastic variant of meningiomas, however, they were later identified as distinct entities clinically and histologically. It is crucial to distinguish hemangiopericytomas from meningiomas, because of their aggressive nature. In this study, we present a rare case of recurrent intracranial hemangiopericytoma with metastases to the spine and brain.
Referanslar
Ahmed O, Menger R, Kukreja S, Zhang S, Storey CM, Nanda A, Guthikonda B: Sacral Nerve Hemangiopericytoma: A Rare Case and Review of the Literatüre. Cancer and Clinical Oncology 1: 4858-4866, 2015.
Begg CF, Garret R: Hemangiopericytoma occuring in the meninges: case report. Cancer 7:602-6, 1954
Cao Y, Zhang MZ, Wang JM, Zhang W, Li G, Zhao JZ: Recurrent intracranial hemangiopericytoma with multiple metastases: case report. Chinese Medical Journal 119(2):169-173, 2006
Chiechi MV, Smirniotopoulos JG, Mena H: Intracranial hemangiopericytomas: MR and CT features. AJNR Am J Neuroradiol 17: 1365-1371, 1996
Cole CD, Schmidt MH: Hemangiopericytomas of the spine: case report and review of the literatüre. Rare Tumors 1(2):e43, 2009
El Hindy N, Ringelstein A, Forsting M, Sure U, Mueller O: Spinal metastasis from malignant meningeal intracranial hemangiopericytoma: one- staged percutaneous Onyx embolization and resection-a technical innovation. World Journal of Surgical Oncology 11:152, 2013
Galanis E, Buckner JC, Scheithauer BW, Kimmel DW, Schomberg PJ, Piepgras DG: Management of recurrent meningeal hemangiopericytoma. Cancer 82: 1915-1920, 1998
Goolner JR, Laws ER, Soule EH, Okazaki H: Hemangiopericytoma of the meninges-Mayo Clinic Experience. Am J Clin Pathol 70: 375-653, 1978
Guthrie BL, Ebersold MJ, Scheithauer BW, Shaw EG: Meningeal hemangiopericytoma: histopathological features, treatment and long-term follow-up of 44 cases. McGraw-Hill Book Company 25: 514-22, 1989
Krause F: Hemangiopericytoma of the menings (angioblastic meningioma of Cushing and Eisenhardt). Clinicopathologic aspects and follow-up studies in 8 cases. Neurology 11: 771-777, 1961
Lee CH, Kim KJ, Jahng TA, Kim HJ: Spinal Hemangiopericytoma Which Needed Intraoperative Embolization due to Unexpected Bleeding. J Korean Neurosurg Soc 54: 253-256, 2013
Lee SJ, Kim ST, Park SH, Choi YL, Park JB, Kim SJ, Lee J: Successful use of pazopanib for treatment of refractory metastatic hemangiopericytoma. Clinical Sarcoma Research 4:13, 2014
Liu G, Chen ZY, Ma L, Lou X, Wang YL: Intracranial hemangiopericytoma: MR imaging findings and diagnostic usefullness of minimum ADC values. J Magn Reson Imaging 38(5): 1146-51, 2013
Marc JA, Takei Y, Schecter MM, Hoffman JC: Intracranial hemangiopericytomas. Angiography, pathology and differential diagnosis. AJR 125: 825-832, 1975
Mena H, Ribas JL, Pezeshkpour GH, cowan DN, Parisi JE: Hemangiopericytoma of the central nervous system: A review of 94 cases. Hum Pathol 22: 84-91, 1991
Osborne DR, Dubois P, Drayer B, Sage M, Burger P, Heinz ER: Primary Intracranial Meningeal and Spinal Hemangiopericytoma: Radiologic Manifestations. AJNR 2:69-74, 1981
Park BJ, Kim Y, Hong YK, Jeun SS: Clinical Analysis of Intracranial Hemangiopericytoma. J Korean Neurosurg Soc 54:309-316, 2013
Park MS, Patel SR, Ludwig JA, Trent JC, Conrad CA, Lazar AJ, Wang WL, Boonsirikamchai P, Choi H, Wang X, Benjamin RS, Araujo DM: Activity of temozalamide and bevacizumab in the treatment of locally advanced, recurrent and metastatic hemangiopericytoma and malignant solitary fibrous tumor. Cancer 117: 4939-4947, 2011
Ren G, Chen S, Wang Y, Zhu RJ, Geng DY, Feng XY: Quantitative evaluation of benign meningioma and hemangiopericytoma with perittumoral brain edema by 64-slice CT perfusion imaging. Chin Med J 123: 2038-2044, 2010
Sheehan J, Kondziolka D, Flickinger J, Lunsford LD: Radiosurgery for Treatment of Recurrent Intracranial Hemangiopericytomas. Neurosurgery 51(4):905-911, 2002
Shin SR, Lee JK, Joo SP, Jung S, Ki SH: Metastatic Hemangiopericytoma to the Cervical Spine from the Cranial Meningeal Hemangiopericytomas: Case Report and Review of Literature. Kor J Spine 1(4):524-528, 2004
Stout AP, Murray MR: Hemangiopericytoma: A Vascular Tumor Featuring Zimmermann’s Pericytes. Annals of surgery 116:26-33, 1942
Thakkar DK, Kuber R, Thakkar DK, Khaladkar SM: Intracranial Haemangiopericytoma: Case Report. International J. Of Healthcare and Biomedical Research 2(3): 77-82, 2014
Tihan T, Viglione M, Rosenblum MK, Olivi A, Burger PC: A Clinicopathologic Review of 18 Cases and Comparison to Meningeal Hemangiopericytomas. Arch Pathol Lab Med 127:432-439, 2003
Veeravagu A, Jiang B, Patil CG, Lee M, Soltys SG, Gibbs IC, Chang SD: CyberKnife Stereotactic Radiosurgery for Recurrent, Metastatic and Residual Hemangiopericytomas. Journal Of Hematology& Oncology 4:26, 2011
Watcharasaksilp W, Limpastan K, Norasathada T, Vaniyapong T: Intracranial hemangiopericytoma with multiple extracranial metastases: a case report. Chiang Mai Medical Journal 52(3-4): 81-86, 2013
Wei G, Kang X, Liu X, Tang X, Li Q, Han J, Yın H: Intracranial meningeal hemangiopericytoma: Recurrences at the initial and distant intracranial sites and extraneural metastases to multiple organs. Molecular and Clinical Oncology 3: 770-774, 2015
Zhang P, Hu J, Zhou D: Hemangiopericytoma of the Cervicothoracic Spine: A Case Report and Literature Review. Turk Neurosurg 24(6):948-953, 2014
Referanslar
Ahmed O, Menger R, Kukreja S, Zhang S, Storey CM, Nanda A, Guthikonda B: Sacral Nerve Hemangiopericytoma: A Rare Case and Review of the Literatüre. Cancer and Clinical Oncology 1: 4858-4866, 2015.
Begg CF, Garret R: Hemangiopericytoma occuring in the meninges: case report. Cancer 7:602-6, 1954
Cao Y, Zhang MZ, Wang JM, Zhang W, Li G, Zhao JZ: Recurrent intracranial hemangiopericytoma with multiple metastases: case report. Chinese Medical Journal 119(2):169-173, 2006
Chiechi MV, Smirniotopoulos JG, Mena H: Intracranial hemangiopericytomas: MR and CT features. AJNR Am J Neuroradiol 17: 1365-1371, 1996
Cole CD, Schmidt MH: Hemangiopericytomas of the spine: case report and review of the literatüre. Rare Tumors 1(2):e43, 2009
El Hindy N, Ringelstein A, Forsting M, Sure U, Mueller O: Spinal metastasis from malignant meningeal intracranial hemangiopericytoma: one- staged percutaneous Onyx embolization and resection-a technical innovation. World Journal of Surgical Oncology 11:152, 2013
Galanis E, Buckner JC, Scheithauer BW, Kimmel DW, Schomberg PJ, Piepgras DG: Management of recurrent meningeal hemangiopericytoma. Cancer 82: 1915-1920, 1998
Goolner JR, Laws ER, Soule EH, Okazaki H: Hemangiopericytoma of the meninges-Mayo Clinic Experience. Am J Clin Pathol 70: 375-653, 1978
Guthrie BL, Ebersold MJ, Scheithauer BW, Shaw EG: Meningeal hemangiopericytoma: histopathological features, treatment and long-term follow-up of 44 cases. McGraw-Hill Book Company 25: 514-22, 1989
Krause F: Hemangiopericytoma of the menings (angioblastic meningioma of Cushing and Eisenhardt). Clinicopathologic aspects and follow-up studies in 8 cases. Neurology 11: 771-777, 1961
Lee CH, Kim KJ, Jahng TA, Kim HJ: Spinal Hemangiopericytoma Which Needed Intraoperative Embolization due to Unexpected Bleeding. J Korean Neurosurg Soc 54: 253-256, 2013
Lee SJ, Kim ST, Park SH, Choi YL, Park JB, Kim SJ, Lee J: Successful use of pazopanib for treatment of refractory metastatic hemangiopericytoma. Clinical Sarcoma Research 4:13, 2014
Liu G, Chen ZY, Ma L, Lou X, Wang YL: Intracranial hemangiopericytoma: MR imaging findings and diagnostic usefullness of minimum ADC values. J Magn Reson Imaging 38(5): 1146-51, 2013
Marc JA, Takei Y, Schecter MM, Hoffman JC: Intracranial hemangiopericytomas. Angiography, pathology and differential diagnosis. AJR 125: 825-832, 1975
Mena H, Ribas JL, Pezeshkpour GH, cowan DN, Parisi JE: Hemangiopericytoma of the central nervous system: A review of 94 cases. Hum Pathol 22: 84-91, 1991
Osborne DR, Dubois P, Drayer B, Sage M, Burger P, Heinz ER: Primary Intracranial Meningeal and Spinal Hemangiopericytoma: Radiologic Manifestations. AJNR 2:69-74, 1981
Park BJ, Kim Y, Hong YK, Jeun SS: Clinical Analysis of Intracranial Hemangiopericytoma. J Korean Neurosurg Soc 54:309-316, 2013
Park MS, Patel SR, Ludwig JA, Trent JC, Conrad CA, Lazar AJ, Wang WL, Boonsirikamchai P, Choi H, Wang X, Benjamin RS, Araujo DM: Activity of temozalamide and bevacizumab in the treatment of locally advanced, recurrent and metastatic hemangiopericytoma and malignant solitary fibrous tumor. Cancer 117: 4939-4947, 2011
Ren G, Chen S, Wang Y, Zhu RJ, Geng DY, Feng XY: Quantitative evaluation of benign meningioma and hemangiopericytoma with perittumoral brain edema by 64-slice CT perfusion imaging. Chin Med J 123: 2038-2044, 2010
Sheehan J, Kondziolka D, Flickinger J, Lunsford LD: Radiosurgery for Treatment of Recurrent Intracranial Hemangiopericytomas. Neurosurgery 51(4):905-911, 2002
Shin SR, Lee JK, Joo SP, Jung S, Ki SH: Metastatic Hemangiopericytoma to the Cervical Spine from the Cranial Meningeal Hemangiopericytomas: Case Report and Review of Literature. Kor J Spine 1(4):524-528, 2004
Stout AP, Murray MR: Hemangiopericytoma: A Vascular Tumor Featuring Zimmermann’s Pericytes. Annals of surgery 116:26-33, 1942
Thakkar DK, Kuber R, Thakkar DK, Khaladkar SM: Intracranial Haemangiopericytoma: Case Report. International J. Of Healthcare and Biomedical Research 2(3): 77-82, 2014
Tihan T, Viglione M, Rosenblum MK, Olivi A, Burger PC: A Clinicopathologic Review of 18 Cases and Comparison to Meningeal Hemangiopericytomas. Arch Pathol Lab Med 127:432-439, 2003
Veeravagu A, Jiang B, Patil CG, Lee M, Soltys SG, Gibbs IC, Chang SD: CyberKnife Stereotactic Radiosurgery for Recurrent, Metastatic and Residual Hemangiopericytomas. Journal Of Hematology& Oncology 4:26, 2011
Watcharasaksilp W, Limpastan K, Norasathada T, Vaniyapong T: Intracranial hemangiopericytoma with multiple extracranial metastases: a case report. Chiang Mai Medical Journal 52(3-4): 81-86, 2013
Wei G, Kang X, Liu X, Tang X, Li Q, Han J, Yın H: Intracranial meningeal hemangiopericytoma: Recurrences at the initial and distant intracranial sites and extraneural metastases to multiple organs. Molecular and Clinical Oncology 3: 770-774, 2015
Zhang P, Hu J, Zhou D: Hemangiopericytoma of the Cervicothoracic Spine: A Case Report and Literature Review. Turk Neurosurg 24(6):948-953, 2014
