Bakteriyel Etkenler

Özet

Afetlerden sonra insan hareketlerinin artması, güvenli olmayan su kullanılmı, hijyen kurallarına dikkat edilememesi, kalabalık yaşam koşulları ve sağlık hizmetlerine ulaşımın kısıtlanması gibi faktörler çeşitli enfeksiyonlara ortam sağlar. Literatür tarandığında afetlerden sonra görülen vektör aracılı enfeksiyonların özellikle paraziter ve viral etkenlerden kaynaklandığı göze çarpmakta olup, vektör aracılı bakteriyel enfeksiyonlarla ilgili veriler oldukça azdır. Ancak afetlerden sonra enkaz yığınlarının kaldırılamaması, yeni yerleşim yerlerinin kurulması, iklim değişiklikleri gibi nedenlerle vektör popülasyonunda artış görülmesi vektör aracılı bakteriyel enfeksiyonlarda da artış yaşanmasına neden olabilir. Vektörlerle bulaşan bakteriyel etkenler Rickettsia spp., Ehrlichia spp., Anaplasma, Orientia tsutsugamushi, Coxiella burnetii, Francisella tularensis ve Borrelia türleridir. Rickettsiales takımında Rickettsia prowazekii, Rickettsia typhi, Rickettsia rickettsii, O. tsutsugamushi, Ehrlichia ve Anaplasma cinsi bakteriler bulunur. Literatür incelendiğinde afetlerden sonra O. tsutsugamushi, F. tularensis ve R. prowazekii  vakalarının arttığını belirten yayınlar göze çarpmaktadır, ancak afetlerden sonra oluşan ortamın vektör popülasyonu artışı üzerinden diğer bakteriyel enfeksiyonların görülme sıklığını da artırabileceği akılda bulundurulmalıdır.

Factors such as increased human movements after disasters, use of unsafe water, failure to pay attention to hygiene rules, crowded living conditions, and restricted access to health services provide an environment for various infections. A review of the literature reveals that viruses and parasites are the main causes of vector-mediated diseases observed following disasters, but there is a lack of information about vector-mediated bacterial infections. Vector-borne bacterial diseases, however, may also rise as a result of an increase in the vector population brought on by factors including the creation of new settlements, the inability to remove debris piles following disasters, and changes in the climate. Rickettsia spp., Ehrlichia spp., Anaplasma, Orientia tsutsugamushi, Coxiella burnetii, Francisella tularensis, and Borrelia spp. are among the bacterial agents that are spread by vectors. Rickettsia prowazekii, Rickettsia typhi, Rickettsia rickettsii, O. tsutsugamushi, Ehrlichia, and Anaplasma genus are members of the order Rickettsiales. It should be noted that while some studies in the literature declare that the incidence of O. tsutsugamushi, F. tularensis, and R. prowazekii cases increased following disasters, there is also evidence that the environment created following disasters may increase the incidence of other bacterial infections due to an increase in the vector population.

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Referanslar

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Mavrouli M, Mavroulis S, Lekkas E, Tsakris A. The Impact of Earthquakes on Public Health: A Narrative Review of Infectious Diseases in the Post-Disaster Period Aiming to Disaster Risk Reduction. Microorganisms 2023; 11: 419.

World Health Organization. Global Vector Control Response 2017-2030. Available from: file:///C:/Users/user/Downloads/9789241512978-eng.pdf (Accessed date: 03.06.2023)

Torto B, Tchouassi DP. Grand challenges in vector-borne disease control targeting vectors. Front Trop Dis 2021; 1:635356.

Quintanilla N. Outbreaks of Vector-borne Infectious Disease Following a Natural Disaster. Georgetown Medical Review 2022; 6(1).

Abdad MY, Abou Abdallah R, Fournier PE, Stenos J, Vasoo S. A Concise Review of the Epidemiology and Diagnostics of Rickettsioses: Rickettsia and Orientia spp. J Clin Microbiol 2018; 56(8).

Drexler NA, Yaglom H, Casal M, Fierro M, Kriner P, Murphy B, et al. Fatal Rocky Mountain spotted fever along the United States Mexico Border, 2013-2016. Emerg Infect Dis 2017; 23(10):1621-1626.

Blanton LS. The Rickettsioses. Infect Dis Clin North Am 2019; 33(1): 213-229.

Jensenius M, Han PV, Schlagenhauf P, Schwartz E, Parola P, Castelli F, et al. Acute and potentially life-threatening tropical diseases in western travelers--a GeoSentinel multicenter study, 1996-2011. Am J Trop Med Hyg 2013; 88(2):397-404.

Raby E, Dyer JR. Endemic (murine) typhus in returned travelers from Asia, a case series: clues to early diagnosis and comparison with dengue. Am J Trop Med Hyg 2013; 88(4):701-703.

LPSN - List of Prokaryotic names with Standing in Nomenclature. Available from: https://www.bacterio.net (Accessed date:14.06.2023).

Drexler N, Nichols Heitman K, Cherry C. Description of Eschar-Associated Rickettsial Diseases Using Passive Surveillance Data — United States, 2010–2016. MMWR Morb Mortal Wkly Rep 2020; 68:1179-1182.

Walker DH. Changing dynamics of human-rickettsial interactions. Am J Trop Med Hyg 2016; 94(1):3-4.

Herrador Z, Fernandez-Martinez A, Gomez-Barroso D, León I, Vieira C, Muro A,et al. Mediterranean spotted fever in Spain, 1997-2014: Epidemiological situation based on hospitalization records. PLoS One 2017;12(3):e0174745.

Burns JN, Acuna-Soto R, Stahle DW. Drought and epidemic typhus, central Mexico, 1655-1918. Emerg Infect Dis 2014; 20(3):442-447.

Angelakis E, Bechah Y, Raoult D. The history of epidemic typhus. Microbiol Spectr 2016;4(4).

Bechah Y, Capo C, Mege JL, Raoult D. Epidemic typhus. Lancet Infect Dis 2008; 8(7):417-426.

Biggs HM, Behravesh CB, Bradley KK, Dahlgren FS, Drexler A, Dumler JS, et al. Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever and other spotted fever group rickettsioses, ehrlichioses, and anaplasmosis - United States. MMWR Recomm Rep 2016; 65(2):1-44.

McQuiston JH, Wiedeman C, Singleton J, Carpenter LR, McElroy K, Mosites E, et al. Inadequacy of IgM antibody tests for diagnosis of Rocky Mountain spotted fever. Am J Trop Med Hyg 2014;91(4):767-770.

Paris DH, Dumler JS. State of the art of diagnosis of rickettsial diseases: the use of blood specimens for diagnosis of scrub typhus, spotted fever group rickettsiosis, and murine typhus. Curr Opin Infect Dis 2016; 29(5):433-439.

Regan JJ, Traeger MS, Humpherys D, Mahoney DL, Martinez M, Emersonet GL, et al. Risk factors for fatal outcome from Rocky Mountain spotted fever in a highly endemic area-Arizona, 2002–2011. Clin Infect Dis 2015; 60(11):1659-1666.

Snowden J, Bartman M, Kong EL, Simonsen KA. Ehrlichiosis. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441966/ (Accessed date: 03.06.2023).

Buzzard SL, Bissell BD, Thompson Bastin ML. Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult. JMM Case Rep 2018; 5(9):e005162.

Center for Disease Control and Prevention. Erlichiosis. Available from: https://www.cdc.gov/ehrlichiosis/healthcare-providers/diagnosis.html (Accessed date: 16/06/2023).

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