Yara Bakımında Geleneksel ve Tamamlayıcı Tedaviler
Özet
Yara; ağrıya, kanamaya, sakatlığa ve ölüme neden olduğu için, yara tedavi ve bakımı çağlar boyunca insanoğlunun yaratıcılığını test etmiştir. Yara tedavisi ve bakımının amacı, yaranın neden olduğu riskleri azaltmak ve olası komplikasyonları en aza indirmektir. Yara tedavisi ve bakımında modern konservatif tedavinin yanı sıra geleneksel ve tamamlayıcı tedaviler sık kullanılmaktadır. Bu kitap bölümünde, yara ve tedavisinde sık kullanılan geleneksel ve tamamlayıcı tedaviler (GETAT) ele alınmaktadır.
Referanslar
Shah JB. The history of wound care. The journal of the American College of Certified Wound Specialists. 2011;3(3):65-66. doi:10.1016/j.jcws.2012.04.002
Yavuz E, Oruç MA. Yaranın tanımı ve oluşum mekanizmaları. Arıca SG, Özkaya H (eds.). Birinci Basamakta Yaraya Yaklaşım içinde. İstanbul: EMA Tıp Kitabevi; 2020. p. 15-19.
Farrar GE, Jr, Kronick A. Wound healing. Clinical Therapy. 1991;13:430-434.
Mirasoğlu B. Yara bakım ürünleri. TOTBID Dergisi. 2015; 14: 456-461. doi:10.14292/totbid.dergisi.2015.65
Lionelli GT, Lawrence WT. Wound dressings. Surgical Clinics of North America. 2003;83(3):617-638. doi:10.1016/S0039-6109(02)00192-5
Ersoy. S. Yara tedavisinde geleneksel ve tamamlayıcı tıp. Arıca SG, Özkaya H (eds.). Birinci Basamakta Yaraya Yaklaşım içinde. İstanbul: EMA Tıp Kitabevi; 2020.p. 211-225.
Altan A, Damlar İ, Aras MH, et al. Sarı kantaronun (hypericum perforatum) yara iyileşmesi üzerine etkisi. Arşiv Kaynak Tarama Dergisi. 2015; 24: 578-591. doi:10.17827/aktd.71433
Gökalp Özkorkmaz E, Özay Y. Yara iyileşmesi ve yara iyileşmesinde kullanılan bazı bitkiler. Derleme Dergisi. 2009;2: 63–67.
Sari AO, Oğuz B, Bilgi A, et al. Ege ve güney marmara bölgelerinde halk ilacı olarak kullanılan bitkiler. Journal of Aegean Agricultural Research Institute. 2010; 20:1-21.
Xing W, Guo W, Zou CH, et al. Acemannan accelerates cell proliferation and skin wound healing through AKT/ Mtor signaling pathway. The Journal of Dermatological Science. 2015;79:101-109. doi:10.1016/j.jdermsci.2015.03.016
Jettanacheawchankit S, Sasithanasate S, Sangvanich P, et al. Acemannan stimulates gingival fibroblast proliferation; expressions of keratinocyte growth factor-1, vascular endothelial grpwth factor, and type I collagen; and wound healing. Journal of Pharmaceutical Sciences. 2009;109:525-531. doi: 10.1254/jphs.08204FP
Attah MO, Jacks TW, Jacob A, et al. The effect of aloe vera (linn) on cutaneous wound healing and wound contraction rate in adult rabbits. Nova Journal of Medical and Biological Sciences. 2016;5:1-8. doi:10.20286/JMBS-050307
Atiba A, Ueno H, Uzuka Y. The Effect of aloe vera oral administration on cutaneous wound healing in type 2 diabetic rats. Journal of Veterinary Medical Science. 2011; 73:583-89. doi: 10.1292/jvms.10-0438
Oryan A, Mohammadalipour A, Moshiri A, et al. Topical application of aloe vera accelerated wound healing, modeling, and remodeling. Annals Plastic Surgery. 2016;77:37-46. doi: 10.1097/SAP.0000000000000239
Maenthaisong R, Chaiyakunapruk N, Niruntraporn S, et al. The efficacy of aloe vera used for burn wound healing: A systematic review. Burns. 2007;33: 713-718. doi: 10.1016/j.burns.2006.10.384
Fronza M, Heinzmann B, Hamburger M, et aI. Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts. The Journal of Ethnopharmacology. 2009;126:463-467. doi: 10.1016/j.jep.2009.09.014
Aro, AA, Perez MO, Vieira CP, et al. Effect of calendula officinalis cream on achilles tendon healing. The Anatomical Record. 2015;298:428-435. doi: 10.1002/ar.23057
Preethi KC, Kuttan G, Kuttan R. Anti-inflammatory activity of flower extract of calendula officinalis linn. and its possible mechanism of action. The Indian Journal of Experimental Biology. 2009; 47:113-120. doi: 10.1515/JBCPP.2009.20.1.73
Parente LM, Andrade MA, Brito LA, et al. Angiogenic activity of calendula officinalis flowers l. in rats. Acta Cirúrgica Brasileira. 2011; 26:19-24. doi:10.1590/S0102-86502011000100005
Duran V., Matic Ö, Jovanovc M, et al. Results of the clinical examination of an ointment with marigold (Calendula officinalis) extract in the treatment of venous leg ulcers. International Journal of Tissue Reactions. 2005;27: 101-106.
Tanideh N, Tavakoli P, Saghiri MA, et al. Healing acceleration in hamsters of oral mucositis ınduced by 5-fluorouracil with topical calendula officinalis. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2013; 115: 332-38. doi:10.1016/j.oooo.2012.08.450
Öztürk N, Korkmaz S, Öztürk Y. Wound-healing activity of st. john’s wort (Hypericum Perforatum L.) on Chicken Embryonic Fibroblasts. The Journal of Ethnopharmacology. 2007;111:33-39. doi:10.1016/j.jep.2006.10.029
Saddiqe Z, Naeem I, Maimoona A. A Review of the antibacterial activity of hypericum perforatum L. The Journal of Ethnopharmacology. 2010; 131: 511-521. doi: 10.1016/j.jep.2010.07.034
Süntar IP, Akkol EK, Yilmazer D, et al. Investigations on the in vivo wound healing potential of hypericum perforatum l. The Journal of Ethnopharmacology. 2010; 127:468-477. doi: 10.1016/j.jep.2009.10.011
Prisacaru AI, Andritoiu CV, Andriescu C, et al. Evaluation of the wound-healing effect of a novel hypericum perforatum ointment in skin ınjury. Romanian Journal of Morphology and Embryology. 2013; 54:1053-1059.
Sayar H, Gergerlioglu N, Seringec N, et al. Comparison of efficacy of topical phenytoin with hypericin in seconddegree burn wound healing: an experimental study in rats. Medical Science Monitor Basic Research. 2014; 20: 36-46. doi: 10.12659/MSMBR.890337
Samadi S, Khadivzadeh T, Emami A, et al. The effect of hypericum perforatum on the wound healing and scar of cesarean. The Journal of Alternative and Complementary Medicine. 2010; 16: 113-117. doi: 10.1089/acm.2009.0317
Damavandi SY, Nejad MC, Jangholi E, et al. Topical hypericum perforatum ımproves tissue regeneration in full-thickness excisional wounds in diabetic rat model. Evidence-Based Complementary and Alternative Medicine. 2015; 245328: 1-4. http://dx.doi.org/10.1155/2015/245328
Chandrika UG, Kumara PAP. Gotu Kola (Centella asiatica): Nutritional properties and plausible health benefits. Advances in Food and Nutrition Research Volume. 2015; 76:125-157. doi: 10.1016/bs.afnr.2015.08.001
Liu M, Dai Y, Li Y, et al. Madecassoside isolated from Cntella asiatica herbs facilitates burn wound healing in mice. Planta Medica; 2008;74:809-815. doi: 10.1055/s-2008-1074533
Basch E, Gabard S, Ulbricht C. Bitter melon (Momordica charantia): A rewiev of efficacy and safety. The American Journal of Health-System Pharmacy. 2003;65:356-359. doi:10.1093/ajhp/60.4.356
Baldemı̇r A, Ekı̇ncı̇ K, İlgün S, et al. Momordica Charantia L. (Kudret Narı) meyvelerinin toplam fenolik madde içerikleri ve antioksidan kapasitelerinin değerlendirilmesi. Derim. 2018;35(1):45-50. doi:10.16882/derim.2018.334177
Teoh SL, Latiff AA, Das S. The effect of topical extract of momordica charantia (bitter gourd) on wound healing in nondiabetic rats and in rats with diabetes ınduced by streptozotocin. Clinical and Experimental Dermatology. 2009; 34: 815-22. doi: 10.1111/j.1365-2230.2008.03117.x
Pişkin A, Altunkaynak BZ, Tümentemur G, et al. The Beneficial Effects of Momordica Charantia (Bitter Gourd) on Wound Healing of Rabbit Skin. Journal of Dermatological Treatment. 2014; 25(4):350-357. doi: 10.3109/09546634.2012.713459
Samancioğlu S, Esen A, Ercan G, et al. A new dressing material in diabetic wounds : Wound healing activity of oleuropein-rich olive leaf extract in diabetic rats. Gaziantep Medical Journal. 2016; 22: 14-21.
Robson V, Dodd S, Thomas S. Standardized antibacterial honey (medihoney) with standard therapy in wound care: randomized clinical trial. Journal of Advanced Nursing. 2009;65(3) :565–575. doi:10.1111/j.1365-2648.2008.04923.x
Tashkandi H. Honey in wound healing: An updated review. Open Life Sciences. 2021;16(1):1091–1100. doi:10.1515/biol-2021-0084
Pieper B. Honey-based dressings and wound care: an option for care in the United States. Journal of Wound Ostomy & Continence Nursing. 2009;36(1):60-68. doi:10.1097/01.won.0000345177.58740.7d
Yaghoobi R, Kazerouni A, Kazerouni O. Evidence for clinical use of honey in wound healing as an anti-bacterial, anti-inflammatory anti-oxidant and anti-viral agent: A review. Jundishapur Journal of Natural Pharmaceutical Products. 2013;8(3):100–104. doi:10.17795/jjnpp-94871.
Fratini F, Cilia G, Turchi B, et al. Beeswax: A minireview of its antimicrobial activity and its application in medicine. Asian Pacific Journal of Tropical Medicine. 2016;9(9): 839-843. doi:10.1016/j.apjtm.2016.07.003
Akbaş D, Aykar FŞ. Yanık yarasında tamamlayıcı ve destekleyici tedavi uygulamaları: sistematik derleme. İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 2021;6(1): 91–95.
Gümüş K, Özlü ZK. The effect of a beeswax, olive oil and Alkanna tinctoria (L.) Tausch mixture on burn injuries: An experimental study with a control group. Complementary Therapies in Medicine. 2017;34: 66–73. doi:10.1016/j.ctim.2017.08.001
Bayir Y, Un H, Ugan RA, et al. The effects of beeswax, olive oil and butter impregnated bandage on burn wound healing. Burns. 2019;45(6): 1410–1417. doi:10.1016/j.burns.2018.03.004
Mohd Zubir MZ, Holloway S, Mohd Noor N. Maggot therapy in wound healing: A systematic review. International Journal of Environmental Research and Public Health. 2020;17(17): 6103. doi:10.3390/ijerph17176103
Nigam Y. The principles of maggot therapy and its role in contemporary wound care. Nursing Times. 2021;117(9):39-44.
Sherman RA. Maggot therapy for treating diabetic foot ulcers unresponsive to conventional therapy. Diabetes Care. 2003;26(2): 446-451. doi:10.2337/diacare.26.2.446
Amrit Pal Singh. Medicinal leech therapy (Hirudotherapy): A brief overview. Complementary Therapies in Clinical Practice. 2010;16:213-215. doi:10.1016/j.ctcp.2009.11.005.
Hajtalebi H., Lurigh H.K. Hajtalebi HR. Treatment of diabetic foot ulcer in a 58-year ol Turk-man patient. Traditional and Integrative Medicine. 2016;1(4):151-159.
Hajtalebi H., Lurigh H.K. Hajtalebi HR. Investigating the treatment status of 10 patients with second- and third- degree diabetic foot ulcers based on the therapeutic protocols of Iranian traditional medicine in Bojnurd from 2015-2016. Asian Journal of Clinical Case Reports for Traditional and Alternative Medicine. 2017;1:55-64. doi:10.22040/ajcrtam.2017.27587
Whitaker IS, Izadi D, Oliver DW, et al. Hirudo medicinalis and plastic surgeon. British Journal of Plastic Surgery. 2004;57:348-353. doi: 10.1016/j.bjps.2003.12.016.
Suh Y, Patel S, Kaitlyn R, et al. Clinical utility of ozone therapy in dental and oral medicine. Medical Gas Research. 2019;9(3):163–167. doi:10.4103/2045-9912.2669974.
Anzolin AP, da Silveira-Kaross NL, Bertol CD. Ozonated oil in wound healing: what has already been proven?. Medical Gas Research. 2020;10(1) :54–59. doi:10.4103/2045-9912.279985
Wen Q, Liu D, Wang X, et al. A systematic review of ozone therapy for treating chronically refractory wounds and ulcers. International Wound Journal. 2022;19(4):853–870. doi:10.1111/iwj.13687.
Houghton PE. Electrical stimulation therapy to promote healing of chronic wounds: a review of reviews. Chronic Wound Care Management and Research. 2017; 4: 25-44. doi: 10.2147/cwcmr.s101323
Pala E, Gencer MZ. Yara tedavisinde geleneksel ve tamamlayıcı tıp. Arıca SG, Özkaya H (eds.). Yara Tedaisinde Yeni Ufuklar içinde. İstanbul: EMA Tıp Kitabevi; 2020.p. 227-234.
Ud-Din S, Sebastian A, Giddings P, et al. Angiogenesis is induced and wound size is reduced by electrical stimulation in an acute wound healing model in human skin. Plos One, 2015; 10(4):e0124502. doi:10.1371/journal.pone.0124502.
Erden S, Çelik SŞ. Bir elektro analjezi yöntemi: transkütan elektriksel sinir stimülasyonu ve hemşirenin rolleri. Hacettepe Üniversitesi Hemşirelik Fakültesi Dergisi, 2015;2(1):50-60.
Jalalvandi F, Ghasemi R, Mirzaei M, et al. Effects of back exercises versus transcutaneous electric nerve stimulation on relief of pain and disability in operating room nurses with chronic non-specific LBP: a randomized clinical trial. BMC Musculoskeletal Disorders. 2022;23(1):291. doi:10.1186/s12891-022-05227-7.
Machado AF, Liebano RE, Furtado F, et al. Effect of high-and low-frequency transcutaneous electrical nerve stimulation on angiogenesis and myofibroblast proliferation in acute excisional wounds in rat skin. Advances in Skin & Wound Care. 2016;29(8):357-363. doi:10.1097/01.ASW.0000488721.83423.f3.
Atalay C, Koçkaya EA, Cetin B, et al. Efficacy of topical nitroglycerin and transcutaneous electrical nerve stimulation on survival of random-pattern skin flaps in rats. Scandinavian Journal of Plastic and Reconstructive Surgery. 2003;37(1):10-3. doi:10.1080/alp.37.1.10.13
Sivaramakrishnan A, Solomon JM, Manikandan N. Comparison of transcutaneous electrical nerve stimulation (TENS) and functional electrical stimulation (FES) for spasticity in spinal cord injury - A pilot randomized cross-over trial. The Journal of Spinal Cord Medicine, 2018;41(4):397-406. doi:10.1080/10790268.2017.1390930
Koca Kutlu A, Ceçen D, Gürgen SG, et al. Comparison study of growth factor expression following treatment with transcutaneous electrical nerve stimulation, saline solution, povidone-ıodine, and lavender oil in wounds Healing. Evidence-based Complementary and Alternative Medicine. 2013;2013:361832. doi: 10.1155/2013/361832.
Sunarmi S, Isworo A, Ari D, et al. The effectiveness of massage therapy on healing of diabetic neuropathy in diabetes mellitus patients. Open Access Macedonian Journal of Medical Sciences. 2022;10:190-194. doi:10.3889/oamjms.2022.8564
Ault P, Plaza A, Paratz J. Scar massage for hypertrophic burns scarring-A systematic review. Burns. 2018;44(1):24-38. doi:10.1016/j.burns.2017.05.006.
Aydınlı A, Deniz Doğan S. Traditional and complementary treatment use in wound care: A descriptive study in Turkey. Journal of Tissue Viability. 2024;S0965-206X(24)00121-9. https://doi.org/10.1016/j.jtv.2024.07.017
Isworo A. Combination of wound treatment and massage for healing diabetic foot ulcers. International Journal of Nursing Education. 2021;13:137-40.
Referanslar
Shah JB. The history of wound care. The journal of the American College of Certified Wound Specialists. 2011;3(3):65-66. doi:10.1016/j.jcws.2012.04.002
Yavuz E, Oruç MA. Yaranın tanımı ve oluşum mekanizmaları. Arıca SG, Özkaya H (eds.). Birinci Basamakta Yaraya Yaklaşım içinde. İstanbul: EMA Tıp Kitabevi; 2020. p. 15-19.
Farrar GE, Jr, Kronick A. Wound healing. Clinical Therapy. 1991;13:430-434.
Mirasoğlu B. Yara bakım ürünleri. TOTBID Dergisi. 2015; 14: 456-461. doi:10.14292/totbid.dergisi.2015.65
Lionelli GT, Lawrence WT. Wound dressings. Surgical Clinics of North America. 2003;83(3):617-638. doi:10.1016/S0039-6109(02)00192-5
Ersoy. S. Yara tedavisinde geleneksel ve tamamlayıcı tıp. Arıca SG, Özkaya H (eds.). Birinci Basamakta Yaraya Yaklaşım içinde. İstanbul: EMA Tıp Kitabevi; 2020.p. 211-225.
Altan A, Damlar İ, Aras MH, et al. Sarı kantaronun (hypericum perforatum) yara iyileşmesi üzerine etkisi. Arşiv Kaynak Tarama Dergisi. 2015; 24: 578-591. doi:10.17827/aktd.71433
Gökalp Özkorkmaz E, Özay Y. Yara iyileşmesi ve yara iyileşmesinde kullanılan bazı bitkiler. Derleme Dergisi. 2009;2: 63–67.
Sari AO, Oğuz B, Bilgi A, et al. Ege ve güney marmara bölgelerinde halk ilacı olarak kullanılan bitkiler. Journal of Aegean Agricultural Research Institute. 2010; 20:1-21.
Xing W, Guo W, Zou CH, et al. Acemannan accelerates cell proliferation and skin wound healing through AKT/ Mtor signaling pathway. The Journal of Dermatological Science. 2015;79:101-109. doi:10.1016/j.jdermsci.2015.03.016
Jettanacheawchankit S, Sasithanasate S, Sangvanich P, et al. Acemannan stimulates gingival fibroblast proliferation; expressions of keratinocyte growth factor-1, vascular endothelial grpwth factor, and type I collagen; and wound healing. Journal of Pharmaceutical Sciences. 2009;109:525-531. doi: 10.1254/jphs.08204FP
Attah MO, Jacks TW, Jacob A, et al. The effect of aloe vera (linn) on cutaneous wound healing and wound contraction rate in adult rabbits. Nova Journal of Medical and Biological Sciences. 2016;5:1-8. doi:10.20286/JMBS-050307
Atiba A, Ueno H, Uzuka Y. The Effect of aloe vera oral administration on cutaneous wound healing in type 2 diabetic rats. Journal of Veterinary Medical Science. 2011; 73:583-89. doi: 10.1292/jvms.10-0438
Oryan A, Mohammadalipour A, Moshiri A, et al. Topical application of aloe vera accelerated wound healing, modeling, and remodeling. Annals Plastic Surgery. 2016;77:37-46. doi: 10.1097/SAP.0000000000000239
Maenthaisong R, Chaiyakunapruk N, Niruntraporn S, et al. The efficacy of aloe vera used for burn wound healing: A systematic review. Burns. 2007;33: 713-718. doi: 10.1016/j.burns.2006.10.384
Fronza M, Heinzmann B, Hamburger M, et aI. Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts. The Journal of Ethnopharmacology. 2009;126:463-467. doi: 10.1016/j.jep.2009.09.014
Aro, AA, Perez MO, Vieira CP, et al. Effect of calendula officinalis cream on achilles tendon healing. The Anatomical Record. 2015;298:428-435. doi: 10.1002/ar.23057
Preethi KC, Kuttan G, Kuttan R. Anti-inflammatory activity of flower extract of calendula officinalis linn. and its possible mechanism of action. The Indian Journal of Experimental Biology. 2009; 47:113-120. doi: 10.1515/JBCPP.2009.20.1.73
Parente LM, Andrade MA, Brito LA, et al. Angiogenic activity of calendula officinalis flowers l. in rats. Acta Cirúrgica Brasileira. 2011; 26:19-24. doi:10.1590/S0102-86502011000100005
Duran V., Matic Ö, Jovanovc M, et al. Results of the clinical examination of an ointment with marigold (Calendula officinalis) extract in the treatment of venous leg ulcers. International Journal of Tissue Reactions. 2005;27: 101-106.
Tanideh N, Tavakoli P, Saghiri MA, et al. Healing acceleration in hamsters of oral mucositis ınduced by 5-fluorouracil with topical calendula officinalis. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2013; 115: 332-38. doi:10.1016/j.oooo.2012.08.450
Öztürk N, Korkmaz S, Öztürk Y. Wound-healing activity of st. john’s wort (Hypericum Perforatum L.) on Chicken Embryonic Fibroblasts. The Journal of Ethnopharmacology. 2007;111:33-39. doi:10.1016/j.jep.2006.10.029
Saddiqe Z, Naeem I, Maimoona A. A Review of the antibacterial activity of hypericum perforatum L. The Journal of Ethnopharmacology. 2010; 131: 511-521. doi: 10.1016/j.jep.2010.07.034
Süntar IP, Akkol EK, Yilmazer D, et al. Investigations on the in vivo wound healing potential of hypericum perforatum l. The Journal of Ethnopharmacology. 2010; 127:468-477. doi: 10.1016/j.jep.2009.10.011
Prisacaru AI, Andritoiu CV, Andriescu C, et al. Evaluation of the wound-healing effect of a novel hypericum perforatum ointment in skin ınjury. Romanian Journal of Morphology and Embryology. 2013; 54:1053-1059.
Sayar H, Gergerlioglu N, Seringec N, et al. Comparison of efficacy of topical phenytoin with hypericin in seconddegree burn wound healing: an experimental study in rats. Medical Science Monitor Basic Research. 2014; 20: 36-46. doi: 10.12659/MSMBR.890337
Samadi S, Khadivzadeh T, Emami A, et al. The effect of hypericum perforatum on the wound healing and scar of cesarean. The Journal of Alternative and Complementary Medicine. 2010; 16: 113-117. doi: 10.1089/acm.2009.0317
Damavandi SY, Nejad MC, Jangholi E, et al. Topical hypericum perforatum ımproves tissue regeneration in full-thickness excisional wounds in diabetic rat model. Evidence-Based Complementary and Alternative Medicine. 2015; 245328: 1-4. http://dx.doi.org/10.1155/2015/245328
Chandrika UG, Kumara PAP. Gotu Kola (Centella asiatica): Nutritional properties and plausible health benefits. Advances in Food and Nutrition Research Volume. 2015; 76:125-157. doi: 10.1016/bs.afnr.2015.08.001
Liu M, Dai Y, Li Y, et al. Madecassoside isolated from Cntella asiatica herbs facilitates burn wound healing in mice. Planta Medica; 2008;74:809-815. doi: 10.1055/s-2008-1074533
Basch E, Gabard S, Ulbricht C. Bitter melon (Momordica charantia): A rewiev of efficacy and safety. The American Journal of Health-System Pharmacy. 2003;65:356-359. doi:10.1093/ajhp/60.4.356
Baldemı̇r A, Ekı̇ncı̇ K, İlgün S, et al. Momordica Charantia L. (Kudret Narı) meyvelerinin toplam fenolik madde içerikleri ve antioksidan kapasitelerinin değerlendirilmesi. Derim. 2018;35(1):45-50. doi:10.16882/derim.2018.334177
Teoh SL, Latiff AA, Das S. The effect of topical extract of momordica charantia (bitter gourd) on wound healing in nondiabetic rats and in rats with diabetes ınduced by streptozotocin. Clinical and Experimental Dermatology. 2009; 34: 815-22. doi: 10.1111/j.1365-2230.2008.03117.x
Pişkin A, Altunkaynak BZ, Tümentemur G, et al. The Beneficial Effects of Momordica Charantia (Bitter Gourd) on Wound Healing of Rabbit Skin. Journal of Dermatological Treatment. 2014; 25(4):350-357. doi: 10.3109/09546634.2012.713459
Samancioğlu S, Esen A, Ercan G, et al. A new dressing material in diabetic wounds : Wound healing activity of oleuropein-rich olive leaf extract in diabetic rats. Gaziantep Medical Journal. 2016; 22: 14-21.
Robson V, Dodd S, Thomas S. Standardized antibacterial honey (medihoney) with standard therapy in wound care: randomized clinical trial. Journal of Advanced Nursing. 2009;65(3) :565–575. doi:10.1111/j.1365-2648.2008.04923.x
Tashkandi H. Honey in wound healing: An updated review. Open Life Sciences. 2021;16(1):1091–1100. doi:10.1515/biol-2021-0084
Pieper B. Honey-based dressings and wound care: an option for care in the United States. Journal of Wound Ostomy & Continence Nursing. 2009;36(1):60-68. doi:10.1097/01.won.0000345177.58740.7d
Yaghoobi R, Kazerouni A, Kazerouni O. Evidence for clinical use of honey in wound healing as an anti-bacterial, anti-inflammatory anti-oxidant and anti-viral agent: A review. Jundishapur Journal of Natural Pharmaceutical Products. 2013;8(3):100–104. doi:10.17795/jjnpp-94871.
Fratini F, Cilia G, Turchi B, et al. Beeswax: A minireview of its antimicrobial activity and its application in medicine. Asian Pacific Journal of Tropical Medicine. 2016;9(9): 839-843. doi:10.1016/j.apjtm.2016.07.003
Akbaş D, Aykar FŞ. Yanık yarasında tamamlayıcı ve destekleyici tedavi uygulamaları: sistematik derleme. İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 2021;6(1): 91–95.
Gümüş K, Özlü ZK. The effect of a beeswax, olive oil and Alkanna tinctoria (L.) Tausch mixture on burn injuries: An experimental study with a control group. Complementary Therapies in Medicine. 2017;34: 66–73. doi:10.1016/j.ctim.2017.08.001
Bayir Y, Un H, Ugan RA, et al. The effects of beeswax, olive oil and butter impregnated bandage on burn wound healing. Burns. 2019;45(6): 1410–1417. doi:10.1016/j.burns.2018.03.004
Mohd Zubir MZ, Holloway S, Mohd Noor N. Maggot therapy in wound healing: A systematic review. International Journal of Environmental Research and Public Health. 2020;17(17): 6103. doi:10.3390/ijerph17176103
Nigam Y. The principles of maggot therapy and its role in contemporary wound care. Nursing Times. 2021;117(9):39-44.
Sherman RA. Maggot therapy for treating diabetic foot ulcers unresponsive to conventional therapy. Diabetes Care. 2003;26(2): 446-451. doi:10.2337/diacare.26.2.446
Amrit Pal Singh. Medicinal leech therapy (Hirudotherapy): A brief overview. Complementary Therapies in Clinical Practice. 2010;16:213-215. doi:10.1016/j.ctcp.2009.11.005.
Hajtalebi H., Lurigh H.K. Hajtalebi HR. Treatment of diabetic foot ulcer in a 58-year ol Turk-man patient. Traditional and Integrative Medicine. 2016;1(4):151-159.
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