Aortik Hastalıklarda Anestezik Yaklaşım ve Preoperatif Değerlendirme

Özet

Aort cerrahisinde preoperatif planlama ve hazırlık, zor ve birçok bileşeni aynı anda düşünmeyi gerektiren bir süreçtir. Yandaş hastalıkların değerlendirilmesi ve koruyucu yaklaşımın planlanması önemlidir. Akut pıhtılaşma bozukluğu yaratabilecek hipotansiyon, dilüsyon, hipotermi ve asidoza karşı dikkatli olunmalıdır. Temel monitörizasyona ek olarak invaziv kan basıncı monitörizasyonu, santral venöz basınç, idrar çıkışı, ısı probu ile vücut sıcaklığı takip edilmeli ve gerekli durumlarda pulmoner arter kataterizasyonu, transözofageal ekokardiyografi (TEE) ve santral nöral monitörizasyon da ilave edilmelidir . Aorta kros klemp konulması, metabolik asidoz, respiratuar alkaloz, katekolaminlerin salınımında artış, toplam vücut oksijen tüketiminde azalma, renal kan akımında azalma, arteryel kan basıncında artış, kardiyak debide artış gibi hemodinamik ve metabolik değişiklikler meydana getirirken; klembin açılması arteryel kan basıncında belirgin azalma, laktat artışı, kardiyak debide azalma, miyokard kontraktilitesinde azalma ve metabolik asidoz gibi hemodinamik ve metabolik değişiklikler meydana getirir. Akut böbrek yetmezliği, abdominal aort cerrahisinde yüksek oranda görülebilecek bir komplikasyondur . Renal koruma için hipotermi, mannitol, dopamin, furosemid, metilprednizolon ve fenoldopam sık kullanılmaktadır; fakat koruyucu etkilerinin kanıtlanması için daha fazla çalışmaya ihtiyaç mevcuttur . Ağrı yönetiminde, lokal anesteziklerle bölgesel blokaj gibi multimodal teknikler de dahil hasta kontrollü sistemik opioid analjezi, bölgesel opioid uygulamaları ve periferik bölgesel teknikler önerilmektedir. Hastalar, ameliyat sonrası gelişebilecek kardiyak komplikasyonların sıklığı, koagülopati, yeniden ısıtma ve hemodinamik stabilizasyon nedeniyle yoğun bakım ünitesinde monitörize takip edilmelidir. Hastanın anamnezi ve kırılganlık seviyesi başarılı bir cerrahi için çok iyi incelenmeli ve planlama yapılmalıdır.

Preoperative planning and preparation in aortic surgery is a difficult process that requires considering many components simultaneously.Evaluation of comorbidities and planning of a preventive approach are important. Care should be taken against hypotension, dilution, hypothermia and acidosis that may cause acute coagulation disorders. In addition to basic monitoring, invasive blood pressure monitoring, central venous pressure, urine output, body temperature with a heat probe should be monitored and, if necessary, pulmonary artery catheterization, transesophageal echocardiography (TEE) and central neural monitoring should be added. While cross-clamping of the aorta causes hemodynamic and metabolic changes such as metabolic acidosis, respiratory alkalosis, increased release of catecholamines, decreased total body oxygen consumption, decreased renal blood flow, increased arterial blood pressure, and increased cardiac output; Opening the clamp causes hemodynamic and metabolic changes such as a significant decrease in arterial blood pressure, increase in lactate, decrease in cardiac output, decrease in myocardial contractility and metabolic acidosis. Acute renal failure is a complication that can be seen at a high rate in abdominal aortic surgery. Hypothermia, mannitol, dopamine, furosemide, methylprednisolone and fenoldopam are frequently used for renal protection; however, further studies are needed to prove their protective effects. In pain management, patient-controlled systemic opioid analgesia, regional opioid applications and peripheral regional techniques are recommended, including multimodal techniques such as regional blockade with local anesthetics. Patients should be monitored in the intensive care unit due to the frequency of cardiac complications that may develop after surgery, coagulopathy, rewarming and hemodynamic stabilization. The patient's history and fragility level should be examined and planned very well for a successful surgery.

Referanslar

Lauren Medina, Shannon Sabo, and Jonathan Vespa. Living Longer: Historical and Projected Life Expectancy in the United States, 1960 to 2060.

Trimarchi S, Eagle KA, Nienaber CA, et al. Role of age in acute type A aortic dissection outcome: Report from the International Registry of Acute Aortic Dissection (IRAD). J Thorac Cardiovasc Surg. 01 Ekim 2010;140(4):784-9.

Rylski B, Hoffmann I, Beyersdorf F, et al. Acute aortic dissection type A: age-related management and outcomes reported in the German Registry for Acute Aortic Dissection Type A (GERAADA) of over 2000 patients. Ann Surg. Mart 2014;259(3):598-604.

Wanamaker KM, Hirji SA, Del Val FR, et al. Proximal aortic surgery in the elderly population: Is advanced age a contraindication for surgery? J Thorac Cardiovasc Surg. 01 Ocak 2019;157(1):53-63.

John F. Butterworth IV, David C. et al. Morgan And Mikhail’s Clinical Anesthesiology, 7th Edition. İçinde: Anesthesia for Cardiovascular Surgery. 7. bs.

Fonseca NM, Pontes JPJ, Perez MV, et al. [SBA 2020: Regional anesthesia guideline for using anticoagulants update]. Braz J Anesthesiol Elsevier. 2020;70(4):364-87.

Healy CF, Doyle M, Egan B, et al. Transfusion requirements and outcomes in patients undergoing abdominal aortic surgery using intra-operative cell salvage. Ir J Med Sci. Mart 2007;176(1):33-6.

Shantikumar S, Patel S, Handa A. The role of cell salvage autotransfusion in abdominal aortic aneurysm surgery. Eur J Vasc Endovasc Surg Off J Eur Soc Vasc Surg. Kasım 2011;42(5):577-84.

Su CH, Qin W, Chen W, et al. Surgical management of acute type A aortic dissection in complicated cases: experience with branch-first aortic arch replacement technique. Chin Med J (Engl). 13 Nisan 2021;134(8):978-80.

Stana J, Peterß S, Prendes CF, et al. [Ascending Aorta and Aortic Arch - Endovascular Therapy Today and in the Future]. Zentralbl Chir. Ekim 2021;146(5):479-85.

Chee YE, Liu SE, Irwin MG. Management of bleeding in vascular surgery. Br J Anaesth. 01 Ocak 2016;117:ii85-94.

Ellard L, Djaiani G. Anaesthesia for vascular emergencies. Anaesthesia. 2013;68(s1):72-83.

Lander H, Zammert M, FitzGerald D. Anticoagulation management during cross-clamping and bypass. Best Pract Res Clin Anaesthesiol. Eylül 2016;30(3):359-70.

Moore MM, Alejandro EU. Aortic Cross-Clamping to Provide Differential Fixation by Perfusion. Curr Protoc. Mart 2021;1(3):e81.

Montenij LJ, Buhre WF, de Jong SA, et al. Arterial pressure waveform analysis versus thermodilution cardiac output measurement during open abdominal aortic aneurysm repair: a prospective observational study. Eur J Anaesthesiol. Ocak 2015;32(1):13-9.

Zammert M, Gelman S. The pathophysiology of aortic cross-clamping. Best Pract Res Clin Anaesthesiol. 01 Eylül 2016;30(3):257-69.

Yeung KK, Groeneveld M, Lu JJN, et al. Organ protection during aortic cross-clamping. Best Pract Res Clin Anaesthesiol. 01 Eylül 2016;30(3):305-15.

Mehta A, O’Donnell TFX, Schutzer R, et al. Evaluating proximal clamp site and intraoperative ischemia time among open repair of juxtarenal aneurysms. J Vasc Surg. Ağustos 2022;76(2):411-8.

Kayatta MO, Chen EP. Optimal temperature management in aortic arch operations. Gen Thorac Cardiovasc Surg. Kasım 2016;64(11):639-50.

Arora L, Hosn MA. Spinal cord perfusion protection for thoraco-abdominal aortic aneurysm surgery. Curr Opin Anaesthesiol. Şubat 2019;32(1):72-9.

Safi HJ, Winnerkvist A, Miller CC, et al. Effect of extended cross-clamp time during thoracoabdominal aortic aneurysm repair. Ann Thorac Surg. Ekim 1998;66(4):1204-9.

Jiao XF, Lin XM, Ni XF, et al. Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials. PloS One. 2019;14(10):e0224562.

Ee L, E A, I S, et al. Biomarkers of inflammation in major vascular surgery: a prospective randomised trial. Acta Anaesthesiol Scand [Internet]. Temmuz 2015 [a.yer 05 Ağustos 2023];59(6). Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/25626738/

D O, T AA, Oa O, et al. Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes. BioMed Res Int [Internet]. 2016 [a.yer 05 Ağustos 2023];2016. Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/27547757/

Arendt KW, Lindley KJ. Obstetric anesthesia management of the patient with cardiac disease. Int J Obstet Anesth. Şubat 2019;37:73-85.

Writing Committee Members, Isselbacher EM, Preventza O, Hamilton Black J, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Thorac Cardiovasc Surg. 28 Haziran 2023;S0022-5223(23)00347-1.

Dresner M, Pinder A. Anaesthesia for caesarean section in women with complex cardiac disease: 34 cases using the Braun Spinocath spinal catheter. Int J Obstet Anesth. Nisan 2009;18(2):131-6.

Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 01 Ocak 2018;67(1):2-77.e2.

Ebeling C, Cheruku S. Anesthetic Management for Endovascular Repair of Thoracic and Abdominal Aortic Aneurysms. Anesthesiol Clin. Aralık 2022;40(4):719-35.

Anesthetic Management for Endovascular Repair of the Thoracic Aorta - PubMed [İnternet]. [a.yer 31 Mayıs 2023]. Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/31677680/

Outcome after endovascular abdominal aortic aneurysm repair: a meta-analysis - PubMed [İnternet]. [a.yer 31 Mayıs 2023]. Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/11958330/

Horlocker TT, Wedel DJ, Rowlingson JC, et al. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Third Edition). Reg Anesth Pain Med. 2010;35(1):64-101.

Edwards MS, Andrews JS, Edwards AF, et al. Results of endovascular aortic aneurysm repair with general, regional, and local/monitored anesthesia care in the American College of Surgeons National Surgical Quality Improvement Program database. J Vasc Surg. Kasım 2011;54(5):1273-82.

Bettex DA, Lachat M, Pfammatter T, et al. To compare general, epidural and local anaesthesia for endovascular aneurysm repair (EVAR). Eur J Vasc Endovasc Surg Off J Eur Soc Vasc Surg. Şubat 2001;21(2):179-84.

Kontopodis N, Galanakis N, Antoniou SA, et al. Meta-Analysis and Meta-Regression Analysis of Outcomes of Endovascular and Open Repair for Ruptured Abdominal Aortic Aneurysm. Eur J Vasc Endovasc Surg Off J Eur Soc Vasc Surg. Mart 2020;59(3):399-410.

Armstrong RA, Squire YG, Rogers CA, et al. Type of Anesthesia for Endovascular Abdominal Aortic Aneurysm Repair. J Cardiothorac Vasc Anesth. Şubat 2019;33(2):462-71.

Moll FL, Powell JT, Fraedrich G, et al. Management of Abdominal Aortic Aneurysms Clinical Practice Guidelines of the European Society for Vascular Surgery. Eur J Vasc Endovasc Surg. 01 Ocak 2011;41:S1-58.

Kimball EJ, Adams DM, Kinikini DV, et al. Delayed Abdominal Closure in the Management of Ruptured Abdominal Aortic Aneurysm. Vascular. 01 Aralık 2009;17(6):309-15.

Dk S, Vr M. Aortic Dissection. Anesthesiol Clin [Internet]. Aralık 2022 [a.yer 07 Ağustos 2023];40(4). Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/36328623/

Referanslar

Lauren Medina, Shannon Sabo, and Jonathan Vespa. Living Longer: Historical and Projected Life Expectancy in the United States, 1960 to 2060.

Trimarchi S, Eagle KA, Nienaber CA, et al. Role of age in acute type A aortic dissection outcome: Report from the International Registry of Acute Aortic Dissection (IRAD). J Thorac Cardiovasc Surg. 01 Ekim 2010;140(4):784-9.

Rylski B, Hoffmann I, Beyersdorf F, et al. Acute aortic dissection type A: age-related management and outcomes reported in the German Registry for Acute Aortic Dissection Type A (GERAADA) of over 2000 patients. Ann Surg. Mart 2014;259(3):598-604.

Wanamaker KM, Hirji SA, Del Val FR, et al. Proximal aortic surgery in the elderly population: Is advanced age a contraindication for surgery? J Thorac Cardiovasc Surg. 01 Ocak 2019;157(1):53-63.

John F. Butterworth IV, David C. et al. Morgan And Mikhail’s Clinical Anesthesiology, 7th Edition. İçinde: Anesthesia for Cardiovascular Surgery. 7. bs.

Fonseca NM, Pontes JPJ, Perez MV, et al. [SBA 2020: Regional anesthesia guideline for using anticoagulants update]. Braz J Anesthesiol Elsevier. 2020;70(4):364-87.

Healy CF, Doyle M, Egan B, et al. Transfusion requirements and outcomes in patients undergoing abdominal aortic surgery using intra-operative cell salvage. Ir J Med Sci. Mart 2007;176(1):33-6.

Shantikumar S, Patel S, Handa A. The role of cell salvage autotransfusion in abdominal aortic aneurysm surgery. Eur J Vasc Endovasc Surg Off J Eur Soc Vasc Surg. Kasım 2011;42(5):577-84.

Su CH, Qin W, Chen W, et al. Surgical management of acute type A aortic dissection in complicated cases: experience with branch-first aortic arch replacement technique. Chin Med J (Engl). 13 Nisan 2021;134(8):978-80.

Stana J, Peterß S, Prendes CF, et al. [Ascending Aorta and Aortic Arch - Endovascular Therapy Today and in the Future]. Zentralbl Chir. Ekim 2021;146(5):479-85.

Chee YE, Liu SE, Irwin MG. Management of bleeding in vascular surgery. Br J Anaesth. 01 Ocak 2016;117:ii85-94.

Ellard L, Djaiani G. Anaesthesia for vascular emergencies. Anaesthesia. 2013;68(s1):72-83.

Lander H, Zammert M, FitzGerald D. Anticoagulation management during cross-clamping and bypass. Best Pract Res Clin Anaesthesiol. Eylül 2016;30(3):359-70.

Moore MM, Alejandro EU. Aortic Cross-Clamping to Provide Differential Fixation by Perfusion. Curr Protoc. Mart 2021;1(3):e81.

Montenij LJ, Buhre WF, de Jong SA, et al. Arterial pressure waveform analysis versus thermodilution cardiac output measurement during open abdominal aortic aneurysm repair: a prospective observational study. Eur J Anaesthesiol. Ocak 2015;32(1):13-9.

Zammert M, Gelman S. The pathophysiology of aortic cross-clamping. Best Pract Res Clin Anaesthesiol. 01 Eylül 2016;30(3):257-69.

Yeung KK, Groeneveld M, Lu JJN, et al. Organ protection during aortic cross-clamping. Best Pract Res Clin Anaesthesiol. 01 Eylül 2016;30(3):305-15.

Mehta A, O’Donnell TFX, Schutzer R, et al. Evaluating proximal clamp site and intraoperative ischemia time among open repair of juxtarenal aneurysms. J Vasc Surg. Ağustos 2022;76(2):411-8.

Kayatta MO, Chen EP. Optimal temperature management in aortic arch operations. Gen Thorac Cardiovasc Surg. Kasım 2016;64(11):639-50.

Arora L, Hosn MA. Spinal cord perfusion protection for thoraco-abdominal aortic aneurysm surgery. Curr Opin Anaesthesiol. Şubat 2019;32(1):72-9.

Safi HJ, Winnerkvist A, Miller CC, et al. Effect of extended cross-clamp time during thoracoabdominal aortic aneurysm repair. Ann Thorac Surg. Ekim 1998;66(4):1204-9.

Jiao XF, Lin XM, Ni XF, et al. Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials. PloS One. 2019;14(10):e0224562.

Ee L, E A, I S, et al. Biomarkers of inflammation in major vascular surgery: a prospective randomised trial. Acta Anaesthesiol Scand [Internet]. Temmuz 2015 [a.yer 05 Ağustos 2023];59(6). Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/25626738/

D O, T AA, Oa O, et al. Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes. BioMed Res Int [Internet]. 2016 [a.yer 05 Ağustos 2023];2016. Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/27547757/

Arendt KW, Lindley KJ. Obstetric anesthesia management of the patient with cardiac disease. Int J Obstet Anesth. Şubat 2019;37:73-85.

Writing Committee Members, Isselbacher EM, Preventza O, Hamilton Black J, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Thorac Cardiovasc Surg. 28 Haziran 2023;S0022-5223(23)00347-1.

Dresner M, Pinder A. Anaesthesia for caesarean section in women with complex cardiac disease: 34 cases using the Braun Spinocath spinal catheter. Int J Obstet Anesth. Nisan 2009;18(2):131-6.

Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 01 Ocak 2018;67(1):2-77.e2.

Ebeling C, Cheruku S. Anesthetic Management for Endovascular Repair of Thoracic and Abdominal Aortic Aneurysms. Anesthesiol Clin. Aralık 2022;40(4):719-35.

Anesthetic Management for Endovascular Repair of the Thoracic Aorta - PubMed [İnternet]. [a.yer 31 Mayıs 2023]. Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/31677680/

Outcome after endovascular abdominal aortic aneurysm repair: a meta-analysis - PubMed [İnternet]. [a.yer 31 Mayıs 2023]. Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/11958330/

Horlocker TT, Wedel DJ, Rowlingson JC, et al. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Third Edition). Reg Anesth Pain Med. 2010;35(1):64-101.

Edwards MS, Andrews JS, Edwards AF, et al. Results of endovascular aortic aneurysm repair with general, regional, and local/monitored anesthesia care in the American College of Surgeons National Surgical Quality Improvement Program database. J Vasc Surg. Kasım 2011;54(5):1273-82.

Bettex DA, Lachat M, Pfammatter T, et al. To compare general, epidural and local anaesthesia for endovascular aneurysm repair (EVAR). Eur J Vasc Endovasc Surg Off J Eur Soc Vasc Surg. Şubat 2001;21(2):179-84.

Kontopodis N, Galanakis N, Antoniou SA, et al. Meta-Analysis and Meta-Regression Analysis of Outcomes of Endovascular and Open Repair for Ruptured Abdominal Aortic Aneurysm. Eur J Vasc Endovasc Surg Off J Eur Soc Vasc Surg. Mart 2020;59(3):399-410.

Armstrong RA, Squire YG, Rogers CA, et al. Type of Anesthesia for Endovascular Abdominal Aortic Aneurysm Repair. J Cardiothorac Vasc Anesth. Şubat 2019;33(2):462-71.

Moll FL, Powell JT, Fraedrich G, et al. Management of Abdominal Aortic Aneurysms Clinical Practice Guidelines of the European Society for Vascular Surgery. Eur J Vasc Endovasc Surg. 01 Ocak 2011;41:S1-58.

Kimball EJ, Adams DM, Kinikini DV, et al. Delayed Abdominal Closure in the Management of Ruptured Abdominal Aortic Aneurysm. Vascular. 01 Aralık 2009;17(6):309-15.

Dk S, Vr M. Aortic Dissection. Anesthesiol Clin [Internet]. Aralık 2022 [a.yer 07 Ağustos 2023];40(4). Erişim adresi: https://pubmed.ncbi.nlm.nih.gov/36328623/

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26 Eylül 2024

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