IgG4 İlişkili Hastalık
Özet
IgG4 ilişkili hastalık, bağışıklık sistemi ile ilişkili bir fibroinflamatuar hastalıktır ve çeşitli organlarda fibrozis ve plazma hücre infiltrasyonuna yol açar. Bu hastalık genellikle IgG4 antikorlarının yüksek seviyeleri ile karakterizedir ve çeşitli klinik sunumlar gösterebilir, bu da tanıyı zorlaştırabilir. Hastalık, özellikle üst solunum yolu, göz, santral sinir sistemi, tiroid, akciğer, lenf bezleri, retroperiton, böbrek, gastrointestinal sistem ve meme dokusu gibi geniş bir yelpazede organları etkileyebilir.
IgG4 ile ilişkili vaskülit, son yıllarda önemli bir konu haline gelmiştir. Bu durum genellikle büyük damarları etkileyebilir ve IgG4 yüksekliği ile ilişkilidir. Özellikle ANCA ilişkili vaskülit, örneğin Churg-Strauss sendromu gibi diğer vaskülit türleriyle ayırt edilmesi gereken bir durumdur. IgG4 ile ilişkili vaskülit, histopatolojik olarak IgG4+ plazma hücrelerinin infiltrasyonunu ve organlarda fibrozis oluşumunu içerir.
Tedavi genellikle glukokortikoidlerle yapılır ve bu tedaviye genellikle uzun süreli ihtiyaç duyulabilir. Erken tanı ve tedavi, hastalığın ilerlemesini ve organ yetmezliği gibi ciddi komplikasyonları önlemeye yardımcı olabilir. Ancak, hastalığın geniş klinik spektrumu ve taklit edici özellikleri nedeniyle tanı zor olabilir ve histopatoloji genellikle kilit rol oynar.
Sonuç olarak, IgG4 ilişkili hastalık geniş bir sistemik etki gösterebilir ve vaskülit gibi belirli komplikasyonları içerebilir. Tanıda histopatoloji kritik öneme sahiptir ve erken tanı ile tedavi sonuçları önemli ölçüde iyileşebilir.
IgG4-related disease is an immune system-related fibroinflammatory condition that leads to fibrosis and plasma cell infiltration in various organs. This disease is typically characterized by high levels of IgG4 antibodies and can present with diverse clinical manifestations, making diagnosis challenging. It can affect a wide range of organs, particularly the upper respiratory tract, eyes, central nervous system, thyroid, lungs, lymph nodes, retroperitoneum, kidneys, gastrointestinal system, and breast tissue.
IgG4-related vasculitis has become a significant topic in recent years. This condition often affects large vessels and is associated with elevated IgG4 levels. It is a condition that needs to be distinguished from other types of vasculitis, especially ANCA-associated vasculitis such as Churg-Strauss syndrome. IgG4-related vasculitis involves histopathologically the infiltration of IgG4+ plasma cells and the formation of fibrosis in organs.
Treatment is typically done with glucocorticoids, and long-term therapy may be required. Early diagnosis and treatment can help prevent serious complications such as disease progression and organ failure, despite the disease's broad clinical spectrum and mimicking features, making diagnosis difficult, and histopathology usually plays a critical role.
In conclusion, IgG4-related disease can have broad systemic effects and include specific complications such as vasculitis. Histopathology is crucial in diagnosis, and early diagnosis can significantly improve treatment outcomes.
Referanslar
Takahashi H, Yamamoto M, Suzuki C, Naishiro Y, Shinomura Y, Imai K. The birthday of a new syndrome: IgG4-related diseases constitute a clinical entity. Autoimmunity Reviews. 2010 Jul;9(9):591-4. doi: 10.1016/j.autrev.2010.05.003.
Lanzillotta M, Mancuso G, Della-Torre E. Advances in the diagnosis and management of IgG4 related disease. The BMJ. 2020 Jun 16;369:m1067. doi: 10.1136/bmj.m1067.
Wu Q, Chang J, Chen H, Chen Y, Yang H, Fei Y, Zhang P, Zeng X, Zhang F, Zhang W. Efficacy between high and medium doses of glucocorticoid therapy in remission induction of IgG4-related diseases: a preliminary randomized controlled trial. International Journal of Rheumatic Diseases. 2017 May;20(5):639-646. doi: 10.1111/1756-185X.13088.
Lanzillotta M, Fernàndez-Codina A, Culver E, Ebbo M, Martinez-Valle F, Schleinitz N, Della-Torre E. Emerging therapy options for IgG4-related disease. Expert Review of Clinical Immunology. 2021 May;17(5):471-483. doi: 10.1080/1744666X.2021.1902310.
Perez Alamino R, Martínez C, Espinoza LR. IgG4-associated vasculitis. Current Rheumatology Reports. 2013 Aug;15(8):348. doi: 10.1007/s11926-013-0348-9.
Imai S, Tahara N, Igata S, Tahara A, Bekki M, Sugiyama Y, Maeda-Ogata S, Honda A, Otsuka H, Ushijima T, Okabe Y, Kaida H, Abe T, Tanaka H, Fukumoto Y, Tayama E. Vascular/perivascular inflammation in IgG4-related disease. Journal of Nuclear Cardiology. 2022 Dec;29(6):2920-2933. doi: 10.1007/s12350-021-02812-6.
Davies AM, Sutton BJ. Human IgG4: a structural perspective. Immunological Reviews. 2015 Nov;268(1):139-59. doi: 10.1111/imr.12349.
Napodano C, Marino M, Stefanile A, Pocino K, Scatena R, Gulli F, Rapaccini GL, Delli Noci S, Capozio G, Rigante D, Basile U. Immunological Role of IgG Subclasses. Immunological Investigations. 2021 May;50(4):427-444.
Michailidou D, Schwartz DM, Mustelin T, Hughes GC. Allergic Aspects of IgG4-Related Disease: Implications for Pathogenesis and Therapy. Frontiers in Immunology. 2021 Jul 7;12:693192. doi: 10.3389/fimmu.2021.693192.
Loock J, Manger B. IgG4-assoziierte Erkrankung [IgG4-related disease]. Zeitschrift für Rheumatologie. 2013 Mar;72(2):151-60; quiz 161-2. German. doi: 10.1007/s00393-012-1104-7.
Aalberse RC, Schuurman J. IgG4 breaking the rules. Immunology. 2002 Jan;105(1):9-19. doi: 10.1046/j.0019-2805.2001.01341.x.
Rispens T, Ooievaar-De Heer P, Vermeulen E, Schuurman J, van der Neut Kolfschoten M, Aalberse RC. Human IgG4 binds to IgG4 and conformationally altered IgG1 via Fc-Fc interactions. The Journal of Immunology. 2009 Apr 1;182(7):4275-81. doi: 10.4049/jimmunol.0804338.
Stone JH, Zen Y, Deshpande V. IgG4-related disease. New England Journal of Medicine. 2012 Feb 9;366(6):539-51. doi: 10.1056/NEJMra1104650. Weindorf SC, Frederiksen JK. IgG4-Related Disease: A Reminder for Practicing Pathologists. Archives of Pathology & Laboratory Medicine. 2017 Nov;141(11):1476-1483. doi: 10.5858/arpa.2017-0257-RA.
Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M. Churg-Strauss syndrome. Autoimmunity Reviews. 2015 Apr;14(4):341-8. doi: 10.1016/j.autrev.2014.12.004. Epub 2014 Dec 11.
Pagnoux C, Guilpain P, Guillevin L. Churg-Strauss syndrome. Current Opinion in Rheumatology. 2007 Jan;19(1):25-32. doi: 10.1097/BOR.0b013e3280119854.
Keogh KA, Specks U. Churg-Strauss syndrome. Seminars in Respiratory and Critical Care Medicine. 2006 Apr;27(2):148-57. doi: 10.1055/s-2006-939518.
Yamamoto M, Takahashi H, Suzuki C, Tabeya T, Ohara M, Naishiro Y, Yamamoto H, Imai K, Shinomura Y. Analysis of serum IgG subclasses in Churg-Strauss syndrome--the meaning of elevated serum levels of IgG4. Internal Medicine. 2010;49(14):1365-70. doi: 10.2169/internalmedicine.49.3532.
Yamamoto M, Tabeya T, Naishiro Y, Yajima H, Ishigami K, Shimizu Y, Obara M, Suzuki C, Yamashita K, Yamamoto H, Hayashi T, Sasaki S, Sugaya T, Ishida T, Takano K, Himi T, Suzuki Y, Nishimoto N, Honda S, Takahashi H, Imai K, Shinomura Y. Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases. Modern Rheumatology. 2012 Jun;22(3):419-25. doi: 10.1007/s10165-011-0532-6.
Vaglio A, Strehl JD, Manger B, Maritati F, Alberici F, Beyer C, Rech J, Sinico RA, Bonatti F, Battistelli L, Distler JH, Schett G, Zwerina J. IgG4 immune response in Churg-Strauss syndrome. Annals of Rheumatic Diseases. 2012 Mar;71(3):390-3. doi: 10.1136/ard.2011.155382.
Kasashima S, Zen Y, Kawashima A, Konishi K, Sasaki H, Endo M, Matsumoto Y, Kawakami K, Kasashima F, Moriya M, Kimura K, Ohtake H, Nakanuma Y. Inflammatory abdominal aortic aneurysm: close relationship to IgG4-related periaortitis. The American Journal of Surgical Pathology. 2008 Feb;32(2):197-204. doi: 10.1097/PAS.0b013e3181342f0d.
Kasashima S, Zen Y, Kawashima A, Endo M, Matsumoto Y, Kasashima F, Ohtake H, Nakanuma Y. A clinicopathologic study of immunoglobulin G4-related sclerosing disease of the thoracic aorta. Journal of Vascular Surgery. 2010 Dec;52(6):1587-95. doi: 10.1016/j.jvs.2010.06.072.
Kasashima S, Kawashima A, Endo M, Matsumoto Y, Kasashima F, Zen Y, Nakanuma Y. A clinicopathologic study of immunoglobulin G4-related disease of the femoral and popliteal arteries in the spectrum of immunoglobulin G4-related periarteritis. Journal of Vascular Surgery. 2013 Mar;57(3):816-22. doi: 10.1016/j.jvs.2012.08.039.
Kasashima S, Zen Y. IgG4-related inflammatory abdominal aortic aneurysm. Current Opinion in Rheumatology. 2011 Jan;23(1):18-23. doi: 10.1097/BOR.0b013e32833ee95f.
Matsumoto Y, Kasashima S, Kawashima A, Sasaki H, Endo M, Kawakami K, Zen Y, Nakanuma Y. A case of multiple immunoglobulin G4-related periarteritis: a tumorous lesion of the coronary artery and abdominal aortic aneurysm. Human Pathology. 2008 Jun;39(6):975-80. doi: 10.1016/j.humpath.2007.10.023.
Ikutomi M, Matsumura T, Iwata H, Nishimura G, Ishizaka N, Hirata Y, Ono M, Nagai R. Giant tumorous lesions (correction of legions) surrounding the right coronary artery associated with immunoglobulin-G4-related systemic disease. Cardiology. 2011;120(1):22-6. doi: 10.1159/000332996.
Ishizaka N. IgG4-related disease underlying the pathogenesis of coronary artery disease. Clinica Chimica Acta. 2013 Jan 16;415:220-5. doi: 10.1016/j.cca.2012.11.003.
Tang T, Boyle JR, Dixon AK, Varty K. Inflammatory abdominal aortic aneurysms. European Journal of Vascular and Endovascular Surgery. 2005 Apr;29(4):353-62. doi: 10.1016/j.ejvs.2004.12.009.
Stone JH, Khosroshahi A, Deshpande V, Stone JR. IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care & Research. 2010 Mar;62(3):316-22. doi: 10.1002/acr.20095.
Adam Z, Adamová Z, Řehák Z, Koukalová R. IgG4-releated disease. Klinicka Onkologie. 2021 Spring;34(2):92-102. English. doi: 10.48095/ccko202192.
Inoue D, Zen Y, Abo H, Gabata T, Demachi H, Yoshikawa J, Miyayama S, Nakanuma Y, Matsui O. Immunoglobulin G4-related periaortitis and periarteritis: CT findings in 17 patients. Radiology. 2011 Nov;261(2):625-33. doi: 10.1148/radiol.11102250.
Inoue D, Yoshida K, Yoneda N, Ozaki K, Matsubara T, Nagai K, Okumura K, Toshima F, Toyama J, Minami T, Matsui O, Gabata T, Zen Y. IgG4-related disease: dataset of 235 consecutive patients. Medicine (Baltimore). 2015 Apr;94(15):e680. doi: 10.1097/MD.0000000000000680.
Sandrasegaran K, Menias CO. Imaging in Autoimmune Pancreatitis and Immunoglobulin G4-Related Disease of the Abdomen. Gastroenterology Clinics of North America. 2018 Sep;47(3):603-619. doi: 10.1016/j.gtc.2018.04.007.
Prucha M, Sedivy P, Stadler P, Zdrahal P, Prokopova P, Voska L, Sedlackova L. Abdominal aortic aneurysm as an IgG4-related disease. Clinical and Experimental Immunology. 2019 Sep;197(3):361-365. doi: 10.1111/cei.13307.
Wallace ZS, Zhang Y, Perugino CA, Naden R, Choi HK, Stone JH; ACR/EULAR IgG4-RD Classification Criteria Committee. Clinical phenotypes of IgG4-related disease: an analysis of two international cross-sectional cohorts. Annals of Rheumatic Diseases. 2019 Mar;78(3):406-412. doi: 10.1136/annrheumdis-2018-214603.
Okazaki K, Chari ST, Frulloni L, Lerch MM, Kamisawa T, Kawa S, Kim MH, Lévy P, Masamune A, Webster G, Shimosegawa T. International consensus for the treatment of autoimmune pancreatitis. Pancreatology. 2017 Jan-Feb;17(1):1-6. doi: 10.1016/j.pan.2016.12.003.
Mizushima I, Inoue D, Yamamoto M, Yamada K, Saeki T, Ubara Y, Matsui S, Masaki Y, Wada T, Kasashima S, Harada K, Takahashi H, Notohara K, Nakanuma Y, Umehara H, Yamagishi M, Kawano M. Clinical course after corticosteroid therapy in IgG4-related aortitis/periaortitis and periarteritis: a retrospective multicenter study. Arthritis Research & Therapy. 2014 Jul 23;16(4):R156. doi: 10.1186/ar4671.
Kasashima S, Kawashima A, Kasashima F, Endo M, Matsumoto Y, Kawakami K, Kayahara M, Ohta H, Yano M, Marukawa Y. Immunoglobulin G4-related periaortitis complicated by aortic rupture and aortoduodenal fistula after endovascular AAA repair. Journal of Endovascular Therapy. 2014 Aug;21(4):589-97.
Tajima M, Hiroi Y, Takazawa Y, Muraoka H, Iwata H, Yamashita H, Hirata Y, Nagai R. Immunoglobulin G4-related multiple systemic aneurysms and splenic aneurysm rupture during steroid therapy. Human Pathology. 2014 Jan;45(1):175-9. doi: 10.1016/j.humpath.2013.07.035.
Carruthers MN, Topazian MD, Khosroshahi A, Witzig TE, Wallace ZS, Hart PA, Deshpande V, Smyrk TC, Chari S, Stone JH. Rituximab for IgG4-related disease: a prospective, open-label trial. Annals Of Rheumatic Diseases. 2015 Jun;74(6):1171-7. doi: 10.1136/annrheumdis-2014-206605.
Referanslar
Takahashi H, Yamamoto M, Suzuki C, Naishiro Y, Shinomura Y, Imai K. The birthday of a new syndrome: IgG4-related diseases constitute a clinical entity. Autoimmunity Reviews. 2010 Jul;9(9):591-4. doi: 10.1016/j.autrev.2010.05.003.
Lanzillotta M, Mancuso G, Della-Torre E. Advances in the diagnosis and management of IgG4 related disease. The BMJ. 2020 Jun 16;369:m1067. doi: 10.1136/bmj.m1067.
Wu Q, Chang J, Chen H, Chen Y, Yang H, Fei Y, Zhang P, Zeng X, Zhang F, Zhang W. Efficacy between high and medium doses of glucocorticoid therapy in remission induction of IgG4-related diseases: a preliminary randomized controlled trial. International Journal of Rheumatic Diseases. 2017 May;20(5):639-646. doi: 10.1111/1756-185X.13088.
Lanzillotta M, Fernàndez-Codina A, Culver E, Ebbo M, Martinez-Valle F, Schleinitz N, Della-Torre E. Emerging therapy options for IgG4-related disease. Expert Review of Clinical Immunology. 2021 May;17(5):471-483. doi: 10.1080/1744666X.2021.1902310.
Perez Alamino R, Martínez C, Espinoza LR. IgG4-associated vasculitis. Current Rheumatology Reports. 2013 Aug;15(8):348. doi: 10.1007/s11926-013-0348-9.
Imai S, Tahara N, Igata S, Tahara A, Bekki M, Sugiyama Y, Maeda-Ogata S, Honda A, Otsuka H, Ushijima T, Okabe Y, Kaida H, Abe T, Tanaka H, Fukumoto Y, Tayama E. Vascular/perivascular inflammation in IgG4-related disease. Journal of Nuclear Cardiology. 2022 Dec;29(6):2920-2933. doi: 10.1007/s12350-021-02812-6.
Davies AM, Sutton BJ. Human IgG4: a structural perspective. Immunological Reviews. 2015 Nov;268(1):139-59. doi: 10.1111/imr.12349.
Napodano C, Marino M, Stefanile A, Pocino K, Scatena R, Gulli F, Rapaccini GL, Delli Noci S, Capozio G, Rigante D, Basile U. Immunological Role of IgG Subclasses. Immunological Investigations. 2021 May;50(4):427-444.
Michailidou D, Schwartz DM, Mustelin T, Hughes GC. Allergic Aspects of IgG4-Related Disease: Implications for Pathogenesis and Therapy. Frontiers in Immunology. 2021 Jul 7;12:693192. doi: 10.3389/fimmu.2021.693192.
Loock J, Manger B. IgG4-assoziierte Erkrankung [IgG4-related disease]. Zeitschrift für Rheumatologie. 2013 Mar;72(2):151-60; quiz 161-2. German. doi: 10.1007/s00393-012-1104-7.
Aalberse RC, Schuurman J. IgG4 breaking the rules. Immunology. 2002 Jan;105(1):9-19. doi: 10.1046/j.0019-2805.2001.01341.x.
Rispens T, Ooievaar-De Heer P, Vermeulen E, Schuurman J, van der Neut Kolfschoten M, Aalberse RC. Human IgG4 binds to IgG4 and conformationally altered IgG1 via Fc-Fc interactions. The Journal of Immunology. 2009 Apr 1;182(7):4275-81. doi: 10.4049/jimmunol.0804338.
Stone JH, Zen Y, Deshpande V. IgG4-related disease. New England Journal of Medicine. 2012 Feb 9;366(6):539-51. doi: 10.1056/NEJMra1104650. Weindorf SC, Frederiksen JK. IgG4-Related Disease: A Reminder for Practicing Pathologists. Archives of Pathology & Laboratory Medicine. 2017 Nov;141(11):1476-1483. doi: 10.5858/arpa.2017-0257-RA.
Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M. Churg-Strauss syndrome. Autoimmunity Reviews. 2015 Apr;14(4):341-8. doi: 10.1016/j.autrev.2014.12.004. Epub 2014 Dec 11.
Pagnoux C, Guilpain P, Guillevin L. Churg-Strauss syndrome. Current Opinion in Rheumatology. 2007 Jan;19(1):25-32. doi: 10.1097/BOR.0b013e3280119854.
Keogh KA, Specks U. Churg-Strauss syndrome. Seminars in Respiratory and Critical Care Medicine. 2006 Apr;27(2):148-57. doi: 10.1055/s-2006-939518.
Yamamoto M, Takahashi H, Suzuki C, Tabeya T, Ohara M, Naishiro Y, Yamamoto H, Imai K, Shinomura Y. Analysis of serum IgG subclasses in Churg-Strauss syndrome--the meaning of elevated serum levels of IgG4. Internal Medicine. 2010;49(14):1365-70. doi: 10.2169/internalmedicine.49.3532.
Yamamoto M, Tabeya T, Naishiro Y, Yajima H, Ishigami K, Shimizu Y, Obara M, Suzuki C, Yamashita K, Yamamoto H, Hayashi T, Sasaki S, Sugaya T, Ishida T, Takano K, Himi T, Suzuki Y, Nishimoto N, Honda S, Takahashi H, Imai K, Shinomura Y. Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases. Modern Rheumatology. 2012 Jun;22(3):419-25. doi: 10.1007/s10165-011-0532-6.
Vaglio A, Strehl JD, Manger B, Maritati F, Alberici F, Beyer C, Rech J, Sinico RA, Bonatti F, Battistelli L, Distler JH, Schett G, Zwerina J. IgG4 immune response in Churg-Strauss syndrome. Annals of Rheumatic Diseases. 2012 Mar;71(3):390-3. doi: 10.1136/ard.2011.155382.
Kasashima S, Zen Y, Kawashima A, Konishi K, Sasaki H, Endo M, Matsumoto Y, Kawakami K, Kasashima F, Moriya M, Kimura K, Ohtake H, Nakanuma Y. Inflammatory abdominal aortic aneurysm: close relationship to IgG4-related periaortitis. The American Journal of Surgical Pathology. 2008 Feb;32(2):197-204. doi: 10.1097/PAS.0b013e3181342f0d.
Kasashima S, Zen Y, Kawashima A, Endo M, Matsumoto Y, Kasashima F, Ohtake H, Nakanuma Y. A clinicopathologic study of immunoglobulin G4-related sclerosing disease of the thoracic aorta. Journal of Vascular Surgery. 2010 Dec;52(6):1587-95. doi: 10.1016/j.jvs.2010.06.072.
Kasashima S, Kawashima A, Endo M, Matsumoto Y, Kasashima F, Zen Y, Nakanuma Y. A clinicopathologic study of immunoglobulin G4-related disease of the femoral and popliteal arteries in the spectrum of immunoglobulin G4-related periarteritis. Journal of Vascular Surgery. 2013 Mar;57(3):816-22. doi: 10.1016/j.jvs.2012.08.039.
Kasashima S, Zen Y. IgG4-related inflammatory abdominal aortic aneurysm. Current Opinion in Rheumatology. 2011 Jan;23(1):18-23. doi: 10.1097/BOR.0b013e32833ee95f.
Matsumoto Y, Kasashima S, Kawashima A, Sasaki H, Endo M, Kawakami K, Zen Y, Nakanuma Y. A case of multiple immunoglobulin G4-related periarteritis: a tumorous lesion of the coronary artery and abdominal aortic aneurysm. Human Pathology. 2008 Jun;39(6):975-80. doi: 10.1016/j.humpath.2007.10.023.
Ikutomi M, Matsumura T, Iwata H, Nishimura G, Ishizaka N, Hirata Y, Ono M, Nagai R. Giant tumorous lesions (correction of legions) surrounding the right coronary artery associated with immunoglobulin-G4-related systemic disease. Cardiology. 2011;120(1):22-6. doi: 10.1159/000332996.
Ishizaka N. IgG4-related disease underlying the pathogenesis of coronary artery disease. Clinica Chimica Acta. 2013 Jan 16;415:220-5. doi: 10.1016/j.cca.2012.11.003.
Tang T, Boyle JR, Dixon AK, Varty K. Inflammatory abdominal aortic aneurysms. European Journal of Vascular and Endovascular Surgery. 2005 Apr;29(4):353-62. doi: 10.1016/j.ejvs.2004.12.009.
Stone JH, Khosroshahi A, Deshpande V, Stone JR. IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care & Research. 2010 Mar;62(3):316-22. doi: 10.1002/acr.20095.
Adam Z, Adamová Z, Řehák Z, Koukalová R. IgG4-releated disease. Klinicka Onkologie. 2021 Spring;34(2):92-102. English. doi: 10.48095/ccko202192.
Inoue D, Zen Y, Abo H, Gabata T, Demachi H, Yoshikawa J, Miyayama S, Nakanuma Y, Matsui O. Immunoglobulin G4-related periaortitis and periarteritis: CT findings in 17 patients. Radiology. 2011 Nov;261(2):625-33. doi: 10.1148/radiol.11102250.
Inoue D, Yoshida K, Yoneda N, Ozaki K, Matsubara T, Nagai K, Okumura K, Toshima F, Toyama J, Minami T, Matsui O, Gabata T, Zen Y. IgG4-related disease: dataset of 235 consecutive patients. Medicine (Baltimore). 2015 Apr;94(15):e680. doi: 10.1097/MD.0000000000000680.
Sandrasegaran K, Menias CO. Imaging in Autoimmune Pancreatitis and Immunoglobulin G4-Related Disease of the Abdomen. Gastroenterology Clinics of North America. 2018 Sep;47(3):603-619. doi: 10.1016/j.gtc.2018.04.007.
Prucha M, Sedivy P, Stadler P, Zdrahal P, Prokopova P, Voska L, Sedlackova L. Abdominal aortic aneurysm as an IgG4-related disease. Clinical and Experimental Immunology. 2019 Sep;197(3):361-365. doi: 10.1111/cei.13307.
Wallace ZS, Zhang Y, Perugino CA, Naden R, Choi HK, Stone JH; ACR/EULAR IgG4-RD Classification Criteria Committee. Clinical phenotypes of IgG4-related disease: an analysis of two international cross-sectional cohorts. Annals of Rheumatic Diseases. 2019 Mar;78(3):406-412. doi: 10.1136/annrheumdis-2018-214603.
Okazaki K, Chari ST, Frulloni L, Lerch MM, Kamisawa T, Kawa S, Kim MH, Lévy P, Masamune A, Webster G, Shimosegawa T. International consensus for the treatment of autoimmune pancreatitis. Pancreatology. 2017 Jan-Feb;17(1):1-6. doi: 10.1016/j.pan.2016.12.003.
Mizushima I, Inoue D, Yamamoto M, Yamada K, Saeki T, Ubara Y, Matsui S, Masaki Y, Wada T, Kasashima S, Harada K, Takahashi H, Notohara K, Nakanuma Y, Umehara H, Yamagishi M, Kawano M. Clinical course after corticosteroid therapy in IgG4-related aortitis/periaortitis and periarteritis: a retrospective multicenter study. Arthritis Research & Therapy. 2014 Jul 23;16(4):R156. doi: 10.1186/ar4671.
Kasashima S, Kawashima A, Kasashima F, Endo M, Matsumoto Y, Kawakami K, Kayahara M, Ohta H, Yano M, Marukawa Y. Immunoglobulin G4-related periaortitis complicated by aortic rupture and aortoduodenal fistula after endovascular AAA repair. Journal of Endovascular Therapy. 2014 Aug;21(4):589-97.
Tajima M, Hiroi Y, Takazawa Y, Muraoka H, Iwata H, Yamashita H, Hirata Y, Nagai R. Immunoglobulin G4-related multiple systemic aneurysms and splenic aneurysm rupture during steroid therapy. Human Pathology. 2014 Jan;45(1):175-9. doi: 10.1016/j.humpath.2013.07.035.
Carruthers MN, Topazian MD, Khosroshahi A, Witzig TE, Wallace ZS, Hart PA, Deshpande V, Smyrk TC, Chari S, Stone JH. Rituximab for IgG4-related disease: a prospective, open-label trial. Annals Of Rheumatic Diseases. 2015 Jun;74(6):1171-7. doi: 10.1136/annrheumdis-2014-206605.
