Benign Huylu Jinekolojik Değişimler ve Tümörler

Özet

Benign oluşumların; oluşum mekanizmaları, hastalık seyri, semptom, tanı ve tedavi yöntemleri hakkında bilgi sahibi olmak hastaların uygun bakım ve danışmanlık hizmeti almasını sağlamaktadır. Non-neoplastik ve neoplastik olmak üzere iki grupta incelenen overyan benign oluşumlar bazen malign neoplazilere dönüşebilmektedir. Leiomyoma, endometrial veya servikal polip gibi uterus ve serviksin benign oluşumları özellikle üreme çağındaki kadınları etkilemekte ve sık karşılaşılmaktadır. Solid veya kistik yapıda görülen benign vulvar tümörler alt genital sistemin nadir görülen bir durumu olmasına rağmen vulva şikayetlerinin ayırıcı tanısında önem taşımaktadır. Aynı şekilde vajinanın benign oluşumlarından olan mezonefrik ve paramezonefrik kanal kistleri ile nadir karşılaşılmasına rağmen malignitenin dışlanması açısından göz önünde bulundurulmalıdır.

Referanslar

Stany, M. P.,& Hamilton, C. A. (2008). Benign disorders of the ovary. Obstetrics and gynecology clinics of North America, 35(2), 271–ix.

Mobeen S, Apostol R. Ovarian Cyst. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560541/

Ehrmann D. A. (2005). Polycystic ovary syndrome. The New England journal of medicine, 352(12), 1223–1236.

Moran, L. J., Hutchison, S. K., Norman, R. J., & Teede, H. J. (2011). Lifestyle changes in women with polycystic ovary syndrome. The Cochrane database of systematic reviews, (2), CD007506.

Gourdy, P., Bachelot, A., Catteau-Jonard, S., Chabbert-Buffet, N., Christin-Maître, S., Conard, J., Fredenrich, A., Gompel, A., Lamiche-Lorenzini, F., Moreau, C., Plu-Bureau, G., Vambergue, A., Vergès, B., & Kerlan, V. (2012). Hormonal contraception in women at risk of vascular and metabolic disorders: guidelines of the French Society of Endocrinology. Annales d'endocrinologie, 73(5), 469–487.

Legro, R. S., Arslanian, S. A., Ehrmann, D. A., Hoeger, K. M., Murad, M. H., Pasquali, R., Welt, C. K., & Endocrine Society (2013). Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. The Journal of clinical endocrinology and metabolism, 98(12), 4565–4592.

Corrigendum to: "Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline". (2021). The Journal of clinical endocrinology and metabolism, 106(6), e2462.

Johnson, N. P., Hummelshoj, L., & World Endometriosis Society Montpellier Consortium (2013). Consensus on current management of endometriosis. Human reproduction (Oxford, England), 28(6), 1552–1568.

Practice Committee of the American Society for Reproductive Medicine (2014). Treatment of pelvic pain associated with endometriosis: a committee opinion. Fertility and sterility, 101(4), 927–935.

Becker, C. M., Bokor, A., Heikinheimo, O., Horne, A., Jansen, F., Kiesel, L., King, K., Kvaskoff, M., Nap, A., Petersen, K., Saridogan, E., Tomassetti, C., van Hanegem, N., Vulliemoz, N., Vermeulen, N., & ESHRE Endometriosis Guideline Group (2022). ESHRE guideline: endometriosis. Human reproduction open, 2022(2), hoac009.

Saunders, P. T. K.,& Horne, A. W. (2021). Endometriosis: Etiology, pathobiology, and therapeutic prospects. Cell, 184(11), 2807–2824.

Limaiem F, Lekkala MR, Mlika M. Ovarian Cystadenoma. [Updated 2023 Jun 18]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK536950/

Montoriol, P. F., Hordonneau, C., Boudinaud, C., Molnar, I., Abrial, C., & Kossai, M. (2021). Benign Brenner tumour of the ovary: CT and MRI features. Clinical radiology, 76(8), 593–598.

Zeyneloğlu, H. B., Öktem, M., Eroğlu, D., Kuşçu, E. (2005). Matür Kistik Teratomlara Laparoskopik Yaklaşım: Başkent Üniversitesi Deneyimi. Galenos Yayınevi, (2)2;116-120.

Pala, A., Ozkan, A., Özdemir, Ö., Erkun, O. (2021). Bir Olgu Sunumu: Matür Kistik Over Teratomu Mature Cystic Ovarian Teratoma: A Case Report. Kocaeli Med J, 10(1);18-22.

Sivanesaratnam, V., Dutta, R., & Jayalakshmi, P. (1990). Ovarian fibroma--clinical and histopathological characteristics. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 33(3), 243–247.

Gui, T., Cao, D., Shen, K., Yang, J., Zhang, Y., Yu, Q., Wan, X., Xiang, Y., Xiao, Y., & Guo, L. (2012). A clinicopathological analysis of 40 cases of ovarian Sertoli-Leydig cell tumors. Gynecologic oncology, 127(2), 384–389.

Tanrıverdi, E. Ç. (2019). Bölüm 70: Uterusun Benign Hastalıkları. Temel Kadın Hastalıkları ve Doğum Bilgisi, Akademisyen Kitabevi, 689-702.

Turan, M. C., Büyükbayrak, E. E. (2004). Myomlarda Tedavi Seçenekleri. TJOD Uzmanlık Sonrası Eğitim Dergisi, 8, 163-169.

Tanır, H. M. (2000). Leiomyom: Tanımı, Tanısı ve Güncel Tedavi Seçenekleri. Türkiye Klinikleri Jinekoloji Obstetri Dergisi, 10, 211-221.

Desteli, G., Bildacı, T. B., Gürsu, T. (2015). Kliniğimizde Anormal Uterin Kanama Nedeniyle Yapılan Endometrial Örnekleme İle Endometrial Polip Tanısı Alan Vakalarının İncelenmesi Ve Eşlik Eden Malignite Oranları. Türk Jinekolojik Onkoloji Dergisi, 2, 46-51.

Günay, T., Yardımcı, O.D., Polat, M., Sandal, K., Şeneldir, H. (2018). Histeroskopik Endometrial Polip Tanılı Hastalarda Polip Lokalizasyonu ve Malignite Riski. Journal Of Clınıcal And Experımental Investıgatıons, 9(2), 95-99.

Çelik, E., Doğan Artaş Z., Kavak,S. B. (2012). Servikal Polip Bulunan Hastalarda Endometriyal Patolojilerin İncelenmesi. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, 26(3), 103-106.

Berzolla, C. E., Schnatz, P. F., O'Sullivan, D. M., Bansal, R., Mandavilli, S., & Sorosky, J. I. (2007). Dysplasia and malignancy in endocervical polyps. Journal of women's health (2002), 16(9), 1317–1321.

Al Julaih GH, Puckett Y. Nabothian Cyst. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559047/

Hickey, M., Ballard, K., & Farquhar, C. (2014). Endometriosis. BMJ (Clinical research ed.), 348, g1752.

Baştu, E., Mutlu, M. F., Serdaroğlu, H. (2012). Endometriyozis Tedavisinde Güncel Yaklaşım. Journal of Istanbul Faculty of Medicine, 75(4), 60-70.

Heller, D. S. (2015). Benign Tumors and Tumor-like Lesions of the Vulva. Clin Obstet Gynecol, 58(3), 526-35.

Erdoğan, G., Şimşir, C. (2022). Office-based management of Bartholin cysts and abscesses: a comparison of three surgical methods. J Health Sci Med, 5(2), 363-367.

Maldonado V. A. (2014). Benign vulvar tumors. Best practice & research. Clinical obstetrics & gynaecology, 28(7), 1088–1097.

Pehlivan, M., Özbay, P. Ö., Temur, M., Yılmaz, Ö., Gümüş, Z., Güzel, A. (2015). Epidermal cyst in an unusual site: A case report. Int J Surg Case Rep., 8C, 114-6.

Yeniocak, A. S., Tercan, C., Dagdeviren, E., Ozbayram, A.C., Goymen, O.D., Saya, M., Karakaya, M. (2023). A Case of Pregnant Woman with a Vaginal Mass in Emergency Department: Gartner's Duct Cyst. Actual Gyn., 15, 104-108.

Thapa, B. D.,& Regmi, M. C. (2020). Gartner's Duct Cyst of the Vagina: A Case Report. JNMA; journal of the Nepal Medical Association, 58(227), 505–507.

Prasad, I., Singh, S., Sr, Sinha, S., Kumar, T., & Roy, I. (2022). A Large Mullerian Cyst With Pressure Symptoms: A Case Report. Cureus, 14(12), e32917.

Esber, A., Radosa, M. P., Wickel, J., Mothes, H. K., Runnebaum, I. B., & Mothes, A. R. (2021). Vaginal cysts: An important differential diagnosis in the anterior compartment. European journal of obstetrics, gynecology, and reproductive biology, 267, 280–284.

Gün Eryılmaz, Ö. (2016). Adenomiyozis. Kocatepe Tıp Dergisi, 17(10), 129-135.

Referanslar

Stany, M. P.,& Hamilton, C. A. (2008). Benign disorders of the ovary. Obstetrics and gynecology clinics of North America, 35(2), 271–ix.

Mobeen S, Apostol R. Ovarian Cyst. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560541/

Ehrmann D. A. (2005). Polycystic ovary syndrome. The New England journal of medicine, 352(12), 1223–1236.

Moran, L. J., Hutchison, S. K., Norman, R. J., & Teede, H. J. (2011). Lifestyle changes in women with polycystic ovary syndrome. The Cochrane database of systematic reviews, (2), CD007506.

Gourdy, P., Bachelot, A., Catteau-Jonard, S., Chabbert-Buffet, N., Christin-Maître, S., Conard, J., Fredenrich, A., Gompel, A., Lamiche-Lorenzini, F., Moreau, C., Plu-Bureau, G., Vambergue, A., Vergès, B., & Kerlan, V. (2012). Hormonal contraception in women at risk of vascular and metabolic disorders: guidelines of the French Society of Endocrinology. Annales d'endocrinologie, 73(5), 469–487.

Legro, R. S., Arslanian, S. A., Ehrmann, D. A., Hoeger, K. M., Murad, M. H., Pasquali, R., Welt, C. K., & Endocrine Society (2013). Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. The Journal of clinical endocrinology and metabolism, 98(12), 4565–4592.

Corrigendum to: "Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline". (2021). The Journal of clinical endocrinology and metabolism, 106(6), e2462.

Johnson, N. P., Hummelshoj, L., & World Endometriosis Society Montpellier Consortium (2013). Consensus on current management of endometriosis. Human reproduction (Oxford, England), 28(6), 1552–1568.

Practice Committee of the American Society for Reproductive Medicine (2014). Treatment of pelvic pain associated with endometriosis: a committee opinion. Fertility and sterility, 101(4), 927–935.

Becker, C. M., Bokor, A., Heikinheimo, O., Horne, A., Jansen, F., Kiesel, L., King, K., Kvaskoff, M., Nap, A., Petersen, K., Saridogan, E., Tomassetti, C., van Hanegem, N., Vulliemoz, N., Vermeulen, N., & ESHRE Endometriosis Guideline Group (2022). ESHRE guideline: endometriosis. Human reproduction open, 2022(2), hoac009.

Saunders, P. T. K.,& Horne, A. W. (2021). Endometriosis: Etiology, pathobiology, and therapeutic prospects. Cell, 184(11), 2807–2824.

Limaiem F, Lekkala MR, Mlika M. Ovarian Cystadenoma. [Updated 2023 Jun 18]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK536950/

Montoriol, P. F., Hordonneau, C., Boudinaud, C., Molnar, I., Abrial, C., & Kossai, M. (2021). Benign Brenner tumour of the ovary: CT and MRI features. Clinical radiology, 76(8), 593–598.

Zeyneloğlu, H. B., Öktem, M., Eroğlu, D., Kuşçu, E. (2005). Matür Kistik Teratomlara Laparoskopik Yaklaşım: Başkent Üniversitesi Deneyimi. Galenos Yayınevi, (2)2;116-120.

Pala, A., Ozkan, A., Özdemir, Ö., Erkun, O. (2021). Bir Olgu Sunumu: Matür Kistik Over Teratomu Mature Cystic Ovarian Teratoma: A Case Report. Kocaeli Med J, 10(1);18-22.

Sivanesaratnam, V., Dutta, R., & Jayalakshmi, P. (1990). Ovarian fibroma--clinical and histopathological characteristics. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 33(3), 243–247.

Gui, T., Cao, D., Shen, K., Yang, J., Zhang, Y., Yu, Q., Wan, X., Xiang, Y., Xiao, Y., & Guo, L. (2012). A clinicopathological analysis of 40 cases of ovarian Sertoli-Leydig cell tumors. Gynecologic oncology, 127(2), 384–389.

Tanrıverdi, E. Ç. (2019). Bölüm 70: Uterusun Benign Hastalıkları. Temel Kadın Hastalıkları ve Doğum Bilgisi, Akademisyen Kitabevi, 689-702.

Turan, M. C., Büyükbayrak, E. E. (2004). Myomlarda Tedavi Seçenekleri. TJOD Uzmanlık Sonrası Eğitim Dergisi, 8, 163-169.

Tanır, H. M. (2000). Leiomyom: Tanımı, Tanısı ve Güncel Tedavi Seçenekleri. Türkiye Klinikleri Jinekoloji Obstetri Dergisi, 10, 211-221.

Desteli, G., Bildacı, T. B., Gürsu, T. (2015). Kliniğimizde Anormal Uterin Kanama Nedeniyle Yapılan Endometrial Örnekleme İle Endometrial Polip Tanısı Alan Vakalarının İncelenmesi Ve Eşlik Eden Malignite Oranları. Türk Jinekolojik Onkoloji Dergisi, 2, 46-51.

Günay, T., Yardımcı, O.D., Polat, M., Sandal, K., Şeneldir, H. (2018). Histeroskopik Endometrial Polip Tanılı Hastalarda Polip Lokalizasyonu ve Malignite Riski. Journal Of Clınıcal And Experımental Investıgatıons, 9(2), 95-99.

Çelik, E., Doğan Artaş Z., Kavak,S. B. (2012). Servikal Polip Bulunan Hastalarda Endometriyal Patolojilerin İncelenmesi. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, 26(3), 103-106.

Berzolla, C. E., Schnatz, P. F., O'Sullivan, D. M., Bansal, R., Mandavilli, S., & Sorosky, J. I. (2007). Dysplasia and malignancy in endocervical polyps. Journal of women's health (2002), 16(9), 1317–1321.

Al Julaih GH, Puckett Y. Nabothian Cyst. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559047/

Hickey, M., Ballard, K., & Farquhar, C. (2014). Endometriosis. BMJ (Clinical research ed.), 348, g1752.

Baştu, E., Mutlu, M. F., Serdaroğlu, H. (2012). Endometriyozis Tedavisinde Güncel Yaklaşım. Journal of Istanbul Faculty of Medicine, 75(4), 60-70.

Heller, D. S. (2015). Benign Tumors and Tumor-like Lesions of the Vulva. Clin Obstet Gynecol, 58(3), 526-35.

Erdoğan, G., Şimşir, C. (2022). Office-based management of Bartholin cysts and abscesses: a comparison of three surgical methods. J Health Sci Med, 5(2), 363-367.

Maldonado V. A. (2014). Benign vulvar tumors. Best practice & research. Clinical obstetrics & gynaecology, 28(7), 1088–1097.

Pehlivan, M., Özbay, P. Ö., Temur, M., Yılmaz, Ö., Gümüş, Z., Güzel, A. (2015). Epidermal cyst in an unusual site: A case report. Int J Surg Case Rep., 8C, 114-6.

Yeniocak, A. S., Tercan, C., Dagdeviren, E., Ozbayram, A.C., Goymen, O.D., Saya, M., Karakaya, M. (2023). A Case of Pregnant Woman with a Vaginal Mass in Emergency Department: Gartner's Duct Cyst. Actual Gyn., 15, 104-108.

Thapa, B. D.,& Regmi, M. C. (2020). Gartner's Duct Cyst of the Vagina: A Case Report. JNMA; journal of the Nepal Medical Association, 58(227), 505–507.

Prasad, I., Singh, S., Sr, Sinha, S., Kumar, T., & Roy, I. (2022). A Large Mullerian Cyst With Pressure Symptoms: A Case Report. Cureus, 14(12), e32917.

Esber, A., Radosa, M. P., Wickel, J., Mothes, H. K., Runnebaum, I. B., & Mothes, A. R. (2021). Vaginal cysts: An important differential diagnosis in the anterior compartment. European journal of obstetrics, gynecology, and reproductive biology, 267, 280–284.

Gün Eryılmaz, Ö. (2016). Adenomiyozis. Kocatepe Tıp Dergisi, 17(10), 129-135.

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