İdiyopatik Fotosensitif Oksipital Lob Epilepsi (IFOLE)
Özet
Oksipital lob epilepsileri % 5- 10 oranında görülmekte, spesifik semptomları nedeniyle tanınması güç olabilmektedir. Etiyolojik olarak semptomatik ve idiyopatik grupta incelenmektedir. İdiyopatik grup, çocukluk çağı benign parsiyel epilepsileri arasında %20-25 oranında saptanmaktadır. En sık vizüel ve okülomotor iktal semptomlar görülmektedir. Fotosensitivite beynin anormal görsel duyarlılık yanıtı şeklinde tanımlanmaktadır. Sıklıkla ergenlerde ve kadınlarda görülmektedir. Epilepsi hastalarında %5 oranında olduğu bilinmektedir. Genetik olarak kalıtıldığı bilinen fotosensitivite; absans, göz kapağı miyoklonisi, jeneralize / fokal miyoklonik sıçramalar, fokal nöbetler, jeneralize tonik klonik nöbetler ve tonik versif nöbetlerle ilişkili olduğu bilinmektedir. Tedavide önleyici yöntemler ailelere açıklanmalı ve ataklar engellenmeye çalışılmalı, gerekiyorsa uygun antiepileptik tedavi önerilmelidir.
Occipital lobe epilepsies are seen in 5-10% of cases and may be difficult to recognize due to their specific symptoms. Etiologically, it is studied in the symptomatic and idiopathic group. The idiopathic group is detected at a rate of 20-25% among childhood benign partial epilepsies. The most common visual and oculomotor ictal symptoms are observed. Photosensitivity is defined as an abnormal visual sensitivity response of the brain. It is often seen in adolescents and women. It is known that it occurs in 5% of epilepsy patients. Genetically inherited photosensitivity is known to be associated with abscess, eyelid myoclonia, generalized / focal myoclonic jercs, focal seizures, generalized tonic-clonic seizures and tonic-versive seizures. Preventive methods of treatment should be explained to families and attacks should be tried to be prevented, appropriate antiepileptic treatment should be recommended if necessary.
Referanslar
Kuzniecky R, Gilliam F, Morawetz R, Faught E, Palmer C, Black L. Occipital lobe developmental malformations and epilepsy: Clinical spectrum, treatment, and outcome. Epilepsia. 1997; 38:175–81.
Adcock JE, Panayiotopoulos CP. Occipital lobe seizures and epilepsies. J Clin Neurophysiol 2012; 29: 397-407.
Panayiotopoulos CP, Michael M, Sanders S, Valeta T, Koutroumanidis M. Benign childhood focal epilepsies: assesment of established and newly recognized syndromes. Brain 2008; 131: 2264-86.
Uludağ İF, Zorlu Y. Oksipital Lob Nöbetleri. Türkiye Klinikleri J Neurol-Özel Konular. 2012; 5(1): 77-83.
Di Bonaventura C, Giallonardo AT, Fattouch J, Manfredi M. Symptoms in focal sensory seizures. Clinical and electroencephalographic features. Seizure 2005; 14:1-9.
Beaumanoir A. History of reflex epilepsy. In: Zifkin BJ, Andermann F, Beaumanoir A, Rowan AJ, editors. Reflex epilepsies and reflex seizures. Advances in Neurology, volume 75. New York: Lippincott-Raven; 1998. p. 139-57.
Baysal L, Bebek N, Baykan B. Photosensitivity and Reflex Epilepsies Epilepsi 2014; 20(Ek 1):23-31
Panayiotopoulos CP. Atlas of epilepsies. Springer 2010. p. 1067124.
de Kovel CG, Pinto D, Tauer U, Lorenz S, Muhle H, Leu C, et al. Whole-genome linkage scan for epilepsy-related photosensitivity: a mega-analysis. Epilepsy Res 2010;89(2-3):286-94.
Striano S, Coppola A, del Gaudio L, Striano P. Reflex seizures and reflex epilepsies: old models for understanding mechanisms of epileptogenesis. Epilepsy Res 2012;100(1-2):1-11.
Koutroumanidis M, Tsatsou K, Sanders S, Michael M, Tan SV, Agathonikou A, et al. Fixation-off sensitivity in epilepsies other than the idiopathic epilepsies of childhood with occipital paroxysms: a 12-year clinical-video EEG study. Epileptic Disord 2009;11(1):20-36.
Referanslar
Kuzniecky R, Gilliam F, Morawetz R, Faught E, Palmer C, Black L. Occipital lobe developmental malformations and epilepsy: Clinical spectrum, treatment, and outcome. Epilepsia. 1997; 38:175–81.
Adcock JE, Panayiotopoulos CP. Occipital lobe seizures and epilepsies. J Clin Neurophysiol 2012; 29: 397-407.
Panayiotopoulos CP, Michael M, Sanders S, Valeta T, Koutroumanidis M. Benign childhood focal epilepsies: assesment of established and newly recognized syndromes. Brain 2008; 131: 2264-86.
Uludağ İF, Zorlu Y. Oksipital Lob Nöbetleri. Türkiye Klinikleri J Neurol-Özel Konular. 2012; 5(1): 77-83.
Di Bonaventura C, Giallonardo AT, Fattouch J, Manfredi M. Symptoms in focal sensory seizures. Clinical and electroencephalographic features. Seizure 2005; 14:1-9.
Beaumanoir A. History of reflex epilepsy. In: Zifkin BJ, Andermann F, Beaumanoir A, Rowan AJ, editors. Reflex epilepsies and reflex seizures. Advances in Neurology, volume 75. New York: Lippincott-Raven; 1998. p. 139-57.
Baysal L, Bebek N, Baykan B. Photosensitivity and Reflex Epilepsies Epilepsi 2014; 20(Ek 1):23-31
Panayiotopoulos CP. Atlas of epilepsies. Springer 2010. p. 1067124.
de Kovel CG, Pinto D, Tauer U, Lorenz S, Muhle H, Leu C, et al. Whole-genome linkage scan for epilepsy-related photosensitivity: a mega-analysis. Epilepsy Res 2010;89(2-3):286-94.
Striano S, Coppola A, del Gaudio L, Striano P. Reflex seizures and reflex epilepsies: old models for understanding mechanisms of epileptogenesis. Epilepsy Res 2012;100(1-2):1-11.
Koutroumanidis M, Tsatsou K, Sanders S, Michael M, Tan SV, Agathonikou A, et al. Fixation-off sensitivity in epilepsies other than the idiopathic epilepsies of childhood with occipital paroxysms: a 12-year clinical-video EEG study. Epileptic Disord 2009;11(1):20-36.
