Karaciğer Nakli Cerrahi Süreci

Özet

21. yüzyılda organ nakli konusundaki gelişmeler ile birlikte son dönem karaciğer yetmezliği olan hastaların pretransplant mortalitesi, posttransplant mortalitenin çok üzerine çıkmıştır. Organ sıkıntısını gidermek amacı ile öncelikle pediatrik alıcılarda başlayan canlı vericili karaciğer transplantasyonu sonrasında erişkinlerde de uygulanmaya başlamış ve sonuçları kadavradan yapılan transplantasyonların sonuçları kadar başarılı olmuştur. Günümüzde özellikle kadavra organ sıkıntısı olan ülkelerde canlı vericiden karaciğer transplantasyonu önemli bir tedavi yöntemi olarak yerini almıştır.
Günümüzde karaciğer yetmezliği olan erişkin ya da pediatrik hastalarda canlı vericili karaciğer transplantasyonu hayat kurtarıcı bir tedavi yöntemi olarak yerini almıştır.

Referanslar

Ito T, Kiuchi T, Yamamoto H, Oike F, Ogura Y, Fujimoto Y, et al.Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications. Transplantation. 2003 Apr 27;75(8):1313–7.doi: 10.1097/01.TP.0000063707.90525.10

Ishiko T, Egawa H, Kasahara M, Nakamura T, Oike F, Kaihara S, et al. Duct-to-Duct Biliary Reconstruction in Living Donor Liver Transplantation Utilizing Right Lobe Graft. Ann Surg. 2002 Aug;236(2):235–40. doi: 10.1097/00000658-200208000-00012

Lo CM, Fan ST, Liu CL, Wong J. Hepatic venoplasty in living-donor liver transplantation using right lobe graft with middle hepatic vein. Transplantation. 2003 Feb 15;75(3):358–60. doi: 10.1097/01.TP.0000046527.19422.3E

Kilic M, Aydin U, Sozbilen M, Ozer I, Tamsel S, Demirpolat G, et al. Comparison between allogenic and autologous vascular conduits in the drainage of anterior sector in right living donor liver transplantation. Transpl Int Off J Eur Soc Organ Transplant. 2007 Aug;20(8):697–701. doi: 10.1111/j.1432-2277.2007.00499.x

Liu CL, Zhao Y, Lo CM, Fan ST. Hepatic venoplasty in right lobe live donor liver transplantation. Liver Transplant Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2003 Dec;9(12):1265–72. doi: 10.1016/j.lts.2003.09.014

Karaca C, Yilmaz C, Ferecov R, Iakobadze Z, Kilic K, Caglayan L, et al. Living-Donor Liver Transplantation for Budd-Chiari Syndrome: Case Series. Transplant Proc.2017Oct;49(8):1841-7.doi: 10.1016/j.transproceed.2017.04.028

Ara C, Akbulut S, Ince V, Karakas S, Baskiran A, Yilmaz S. Living donor liver transplantation for Budd-Chiari syndrome: Overcoming a troublesome situation. Medicine (Baltimore). 2016 Oct;95(43):e5136. doi: 10.1097/MD.0000000000005136

Kilic M, Farajov R, Iakobadze Z, Akcalar S, Camli D, Kilic K, et al. Portal Vein Pull-Through Technique and Thrombectomy for Extensive Portal Vein Thrombosis. Transplant Proc. 2023 Mar;55(2):375–8. doi: 10.1016/j.transproceed.2023.02.008

Alper M, Gundogan H, Tokat C, Ozek C. Microsurgical reconstruction of hepatic artery during living donor liver transplantation. Microsurgery. 2005;25(5):378–83;discussion 383-384. doi: 10.1002/micr.20145

Calne RY. A new technique for biliary drainage in orthotopic liver transplantation utilizing the gall bladder as a pedicle graft conduit between the donor and recipient common bile ducts. Ann Surg. 1976 Nov;184(5):605–9. doi: 10.1097/00000658-197611000-00012

Icoz G, Kilic M, Zeytunlu M, Celebi A, Ersoz G, Killi R, et al. Biliary reconstructions and complications encountered in 50 consecutive right-lobe living donor liver transplantations. Liver Transplant Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2003 Jun;9(6):575–80. doi: 10.1053/jlts.2003.50129

Kawachi S, Shimazu M, Wakabayashi G, Hoshino K, Tanabe M, Yoshida M, et al. Biliary complications in adult living donor liver transplantation with duct-to-duct hepaticocholedochostomy or Roux-en-Y hepaticojejunostomy biliary reconstruction. Surgery.2002 Jul;132(1):48–56. doi: 10.1067/msy.2002.125314

Shah SA, Grant DR, McGilvray ID, Greig PD, Selzner M, Lilly LB, et al. Biliary strictures in 130 consecutive right lobe living donör liver transplant recipients: results of a Western center. Am J Trans plant Off J Am Soc Transplant Am Soc Transpl Surg. 2007 Jan;7(1):161–7. doi: 10.1111/j.1600-6143.2006.01601.x

Shokouh-Amiri MH, Grewal HP, Vera SR, Stratta RJ, Bagous W, Gaber AO. Duct-to-duct biliary reconstruction in right lobe adult living donor liver transplantation. J Am Coll Surg. 2001 Jun;192(6):798–803. doi: 10.1016/s1072-7515(01)00854

Gondolesi GE, Varotti G, Florman SS, Muñoz L, Fishbein TM,Emre SH, et al. Biliary complications in 96 consecutive right lobe living donor transplant recipients. Transplantation. 2004 Jun 27;77(12):1842–8. doi: 10.1097/01.tp.0000123077.78702.0c

Lee KW, Joh JW, Kim SJ, Choi SH, Heo JS, Lee HH, et al. High hilar dissection: new technique to reduce biliary complication in living donor liver transplantation. Liver Transplant Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2004 Sep;10(9):1158–62. doi: 10.1002/lt.20230

Fan ST, Lo CM, Liu CL, Tso WK, Wong J. Biliary reconstruction and complications of right lobe live donor liver transplantation. Ann Surg. 2002 Nov;236(5):676–83. doi: 10.1097/00000658

Referanslar

Ito T, Kiuchi T, Yamamoto H, Oike F, Ogura Y, Fujimoto Y, et al.Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications. Transplantation. 2003 Apr 27;75(8):1313–7.doi: 10.1097/01.TP.0000063707.90525.10

Ishiko T, Egawa H, Kasahara M, Nakamura T, Oike F, Kaihara S, et al. Duct-to-Duct Biliary Reconstruction in Living Donor Liver Transplantation Utilizing Right Lobe Graft. Ann Surg. 2002 Aug;236(2):235–40. doi: 10.1097/00000658-200208000-00012

Lo CM, Fan ST, Liu CL, Wong J. Hepatic venoplasty in living-donor liver transplantation using right lobe graft with middle hepatic vein. Transplantation. 2003 Feb 15;75(3):358–60. doi: 10.1097/01.TP.0000046527.19422.3E

Kilic M, Aydin U, Sozbilen M, Ozer I, Tamsel S, Demirpolat G, et al. Comparison between allogenic and autologous vascular conduits in the drainage of anterior sector in right living donor liver transplantation. Transpl Int Off J Eur Soc Organ Transplant. 2007 Aug;20(8):697–701. doi: 10.1111/j.1432-2277.2007.00499.x

Liu CL, Zhao Y, Lo CM, Fan ST. Hepatic venoplasty in right lobe live donor liver transplantation. Liver Transplant Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2003 Dec;9(12):1265–72. doi: 10.1016/j.lts.2003.09.014

Karaca C, Yilmaz C, Ferecov R, Iakobadze Z, Kilic K, Caglayan L, et al. Living-Donor Liver Transplantation for Budd-Chiari Syndrome: Case Series. Transplant Proc.2017Oct;49(8):1841-7.doi: 10.1016/j.transproceed.2017.04.028

Ara C, Akbulut S, Ince V, Karakas S, Baskiran A, Yilmaz S. Living donor liver transplantation for Budd-Chiari syndrome: Overcoming a troublesome situation. Medicine (Baltimore). 2016 Oct;95(43):e5136. doi: 10.1097/MD.0000000000005136

Kilic M, Farajov R, Iakobadze Z, Akcalar S, Camli D, Kilic K, et al. Portal Vein Pull-Through Technique and Thrombectomy for Extensive Portal Vein Thrombosis. Transplant Proc. 2023 Mar;55(2):375–8. doi: 10.1016/j.transproceed.2023.02.008

Alper M, Gundogan H, Tokat C, Ozek C. Microsurgical reconstruction of hepatic artery during living donor liver transplantation. Microsurgery. 2005;25(5):378–83;discussion 383-384. doi: 10.1002/micr.20145

Calne RY. A new technique for biliary drainage in orthotopic liver transplantation utilizing the gall bladder as a pedicle graft conduit between the donor and recipient common bile ducts. Ann Surg. 1976 Nov;184(5):605–9. doi: 10.1097/00000658-197611000-00012

Icoz G, Kilic M, Zeytunlu M, Celebi A, Ersoz G, Killi R, et al. Biliary reconstructions and complications encountered in 50 consecutive right-lobe living donor liver transplantations. Liver Transplant Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2003 Jun;9(6):575–80. doi: 10.1053/jlts.2003.50129

Kawachi S, Shimazu M, Wakabayashi G, Hoshino K, Tanabe M, Yoshida M, et al. Biliary complications in adult living donor liver transplantation with duct-to-duct hepaticocholedochostomy or Roux-en-Y hepaticojejunostomy biliary reconstruction. Surgery.2002 Jul;132(1):48–56. doi: 10.1067/msy.2002.125314

Shah SA, Grant DR, McGilvray ID, Greig PD, Selzner M, Lilly LB, et al. Biliary strictures in 130 consecutive right lobe living donör liver transplant recipients: results of a Western center. Am J Trans plant Off J Am Soc Transplant Am Soc Transpl Surg. 2007 Jan;7(1):161–7. doi: 10.1111/j.1600-6143.2006.01601.x

Shokouh-Amiri MH, Grewal HP, Vera SR, Stratta RJ, Bagous W, Gaber AO. Duct-to-duct biliary reconstruction in right lobe adult living donor liver transplantation. J Am Coll Surg. 2001 Jun;192(6):798–803. doi: 10.1016/s1072-7515(01)00854

Gondolesi GE, Varotti G, Florman SS, Muñoz L, Fishbein TM,Emre SH, et al. Biliary complications in 96 consecutive right lobe living donor transplant recipients. Transplantation. 2004 Jun 27;77(12):1842–8. doi: 10.1097/01.tp.0000123077.78702.0c

Lee KW, Joh JW, Kim SJ, Choi SH, Heo JS, Lee HH, et al. High hilar dissection: new technique to reduce biliary complication in living donor liver transplantation. Liver Transplant Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2004 Sep;10(9):1158–62. doi: 10.1002/lt.20230

Fan ST, Lo CM, Liu CL, Tso WK, Wong J. Biliary reconstruction and complications of right lobe live donor liver transplantation. Ann Surg. 2002 Nov;236(5):676–83. doi: 10.1097/00000658

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