Kanserlerin Önlenmesinde Probiyotiklerin Rolü

Guarner, F., Casellas, F., Borruel, N., Antolìn, M., Videla, S., and VilasecaMalagelada, J., Jr (2003). Gut flora in health and disease. Gut flora health Dis. Lancet 361, 512–519. doi:10. 1016/S0140-6736(03)12489-0.

Samanta S. Potential Impacts of Prebiotics and Probiotics on Cancer Prevention. Anticancer Agents Med Chem. 2022;22(4):605-628. doi:10.2174/1871520621999201210220442.

Fong W, Li Q, Yu J. Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer. Oncogene. 2020;39(26):4925-4943. Doi:10.1038/s41388-020-1341-1.

Kamada N, Kim YG, Sham HP, et al. Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science. 2012;336(6086):1325-1329. Doi:10.1126/science.1222195.

Tuomola EM, Ouwehand AC, Salminen SJ. The effect of probiotic bacteria on the adhesion of pathogens to human intestinal mucus. FEMS Immunol Med Microbiol. 1999;26(2):137-142. doi:10.1111/j.1574-695X.1999.tb01381.x.

Fayol-Messaoudi D, Berger CN, Coconnier-Polter MH, Liévin-Le Moal V, Servin AL. pH-, Lactic acid-, and non-lactic acid-dependent activities of probiotic Lactobacilli against Salmonella enterica Serovar Typhimurium. Appl Environ Microbiol. 2005;71(10):6008-6013. Doi:10.1128/AEM.71.10.6008-6013.2005.

Gillor O, Etzion A, Riley MA. The dual role of bacteriocins as anti- and probiotics. Appl Microbiol Biotechnol. 2008;81(4):591-606. doi:10.1007/s00253-008-1726-5.

Klaenhammer TR, Kleerebezem M, Kopp MV, Rescigno M. The impact of probiotics and prebiotics on the immune system. Nat Rev Immunol. 2012;12(10):728-734. doi:10.1038/nri3312.

Konieczna P, Groeger D, Ziegler M, et al. Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells. Gut. 2012;61(3):354-366. doi:10.1136/gutjnl-2011-300936.

Jeon SG, Kayama H, Ueda Y, et al. Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon. PLoS Pathog. 2012;8(5):e1002714. doi: 10.1371/journal.ppat.1002714.

Ghadimi D, Helwig U, Schrezenmeir J, Heller KJ, de Vrese M. Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system. J Leukoc Biol. 2012;92(4):895-911. doi:10.1189/jlb.0611286.

Chen L, Zou Y, Peng J, et al. Lactobacillus acidophilus suppresses colitis-associated activation of the IL-23/Th17 axis. J Immunol Res. 2015; 2015:909514. Doi:10.1155/2015/909514.

Sichetti M, De Marco S, Pagiotti R, Traina G, Pietrella D. Anti-inflammatory effect of multistrain probiotic formulation (L. rhamnosus, B. lactis, and B. longum). Nutrition. 2018; 53:95-102. Doi: 10.1016/j.nut.2018.02.005.

Mohamadzadeh M, Pfeiler EA, Brown JB, et al. Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A. 2011;108 Suppl 1(Suppl 1):4623-4630. Doi:10.1073/pnas.1005066107.

Khazaie K, Zadeh M, Khan MW, et al. Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A. 2012;109(26):10462-10467. Doi:10.1073/pnas.1207230109.

Soler AP, Miller RD, Laughlin KV, Carp NZ, Klurfeld DM, Mullin JM. Increased tight junctional permeability is associated with the development of colon cancer. Carcinogenesis. 1999;20(8):1425-1431. Doi:10.1093/carcin/20.8.1425.

Puppa MJ, White JP, Sato S, Cairns M, Baynes JW, Carson JA. Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. Biochim Biophys Acta. 2011;1812(12):1601-1606. Doi: 10.1016/j.bbadis.2011.08.010.

Ahmad R, Kumar B, Chen Z, et al. Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy by hyperactivating Wnt/β-catenin signaling. Oncogene. 2017;36(47):6592-6604. Doi:10.1038/onc.2017.259.

Wang L, Cao H, Liu L, et al. Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein. J Biol Chem. 2014;289(29):20234-20244. Doi:10.1074/jbc.M114.553800.

Martín R, Chamignon C, Mhedbi-Hajri N, et al. The potential probiotic Lactobacillus rhamnosus CNCM I-3690 strain protects the intestinal barrier by stimulating both mucus production and cytoprotective response. Sci Rep. 2019;9(1):5398. Published 2019 Apr 1. doi:10.1038/s41598-019-41738-5.

Kumar M, Kissoon-Singh V, Coria AL, Moreau F, Chadee K. Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2017;312(1): G34-G45. doi:10.1152/ajpgi.00298.2016.

Geller LT, Barzily-Rokni M, Danino T, et al. Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science. 2017;357(6356):1156-1160. Doi:10.1126/science.aah5043.

Pakbin B, Dibazar SP, Allahyari S, et al. Anticancer Properties of Probiotic Saccharomyces boulardii Supernatant on Human Breast Cancer Cells. Probiotics Antimicrob Proteins. 2022;14(6):1130-1138. Doi:10.1007/s12602-021-09756-w.

Pakbin B, Allahyari S, Dibazar SP, et al. Anticancer Properties of Saccharomyces boulardii Metabolite Against Colon Cancer Cells. Probiotics Antimicrob Proteins. 2024;16(1):224-232. doi:10.1007/s12602-022-10030-w.

Pakbin B, Allahyari S, Dibazar SP, et al. Effects of Probiotic Saccharomyces boulardii Supernatant on Viability, Nano-Mechanical Properties of Cytoplasmic Membrane and Pro-Inflammatory Gene Expression in Human Gastric Cancer AGS Cells. Int J Mol Sci. 2023;24(9):7945. Published 2023 Apr 27. doi:10.3390/ijms24097945.

Guarner, F., Casellas, F., Borruel, N., Antolìn, M., Videla, S., and VilasecaMalagelada, J., Jr (2003). Gut flora in health and disease. Gut flora health Dis. Lancet 361, 512–519. doi:10. 1016/S0140-6736(03)12489-0.

Samanta S. Potential Impacts of Prebiotics and Probiotics on Cancer Prevention. Anticancer Agents Med Chem. 2022;22(4):605-628. doi:10.2174/1871520621999201210220442.

Fong W, Li Q, Yu J. Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer. Oncogene. 2020;39(26):4925-4943. Doi:10.1038/s41388-020-1341-1.

Kamada N, Kim YG, Sham HP, et al. Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science. 2012;336(6086):1325-1329. Doi:10.1126/science.1222195.

Tuomola EM, Ouwehand AC, Salminen SJ. The effect of probiotic bacteria on the adhesion of pathogens to human intestinal mucus. FEMS Immunol Med Microbiol. 1999;26(2):137-142. doi:10.1111/j.1574-695X.1999.tb01381.x.

Fayol-Messaoudi D, Berger CN, Coconnier-Polter MH, Liévin-Le Moal V, Servin AL. pH-, Lactic acid-, and non-lactic acid-dependent activities of probiotic Lactobacilli against Salmonella enterica Serovar Typhimurium. Appl Environ Microbiol. 2005;71(10):6008-6013. Doi:10.1128/AEM.71.10.6008-6013.2005.

Gillor O, Etzion A, Riley MA. The dual role of bacteriocins as anti- and probiotics. Appl Microbiol Biotechnol. 2008;81(4):591-606. doi:10.1007/s00253-008-1726-5.

Klaenhammer TR, Kleerebezem M, Kopp MV, Rescigno M. The impact of probiotics and prebiotics on the immune system. Nat Rev Immunol. 2012;12(10):728-734. doi:10.1038/nri3312.

Konieczna P, Groeger D, Ziegler M, et al. Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells. Gut. 2012;61(3):354-366. doi:10.1136/gutjnl-2011-300936.

Jeon SG, Kayama H, Ueda Y, et al. Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon. PLoS Pathog. 2012;8(5):e1002714. doi: 10.1371/journal.ppat.1002714.

Ghadimi D, Helwig U, Schrezenmeir J, Heller KJ, de Vrese M. Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system. J Leukoc Biol. 2012;92(4):895-911. doi:10.1189/jlb.0611286.

Chen L, Zou Y, Peng J, et al. Lactobacillus acidophilus suppresses colitis-associated activation of the IL-23/Th17 axis. J Immunol Res. 2015; 2015:909514. Doi:10.1155/2015/909514.

Sichetti M, De Marco S, Pagiotti R, Traina G, Pietrella D. Anti-inflammatory effect of multistrain probiotic formulation (L. rhamnosus, B. lactis, and B. longum). Nutrition. 2018; 53:95-102. Doi: 10.1016/j.nut.2018.02.005.

Mohamadzadeh M, Pfeiler EA, Brown JB, et al. Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A. 2011;108 Suppl 1(Suppl 1):4623-4630. Doi:10.1073/pnas.1005066107.

Khazaie K, Zadeh M, Khan MW, et al. Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A. 2012;109(26):10462-10467. Doi:10.1073/pnas.1207230109.

Soler AP, Miller RD, Laughlin KV, Carp NZ, Klurfeld DM, Mullin JM. Increased tight junctional permeability is associated with the development of colon cancer. Carcinogenesis. 1999;20(8):1425-1431. Doi:10.1093/carcin/20.8.1425.

Puppa MJ, White JP, Sato S, Cairns M, Baynes JW, Carson JA. Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. Biochim Biophys Acta. 2011;1812(12):1601-1606. Doi: 10.1016/j.bbadis.2011.08.010.

Ahmad R, Kumar B, Chen Z, et al. Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy by hyperactivating Wnt/β-catenin signaling. Oncogene. 2017;36(47):6592-6604. Doi:10.1038/onc.2017.259.

Wang L, Cao H, Liu L, et al. Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein. J Biol Chem. 2014;289(29):20234-20244. Doi:10.1074/jbc.M114.553800.

Martín R, Chamignon C, Mhedbi-Hajri N, et al. The potential probiotic Lactobacillus rhamnosus CNCM I-3690 strain protects the intestinal barrier by stimulating both mucus production and cytoprotective response. Sci Rep. 2019;9(1):5398. Published 2019 Apr 1. doi:10.1038/s41598-019-41738-5.

Kumar M, Kissoon-Singh V, Coria AL, Moreau F, Chadee K. Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2017;312(1): G34-G45. doi:10.1152/ajpgi.00298.2016.

Geller LT, Barzily-Rokni M, Danino T, et al. Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science. 2017;357(6356):1156-1160. Doi:10.1126/science.aah5043.

Pakbin B, Dibazar SP, Allahyari S, et al. Anticancer Properties of Probiotic Saccharomyces boulardii Supernatant on Human Breast Cancer Cells. Probiotics Antimicrob Proteins. 2022;14(6):1130-1138. Doi:10.1007/s12602-021-09756-w.

Pakbin B, Allahyari S, Dibazar SP, et al. Anticancer Properties of Saccharomyces boulardii Metabolite Against Colon Cancer Cells. Probiotics Antimicrob Proteins. 2024;16(1):224-232. doi:10.1007/s12602-022-10030-w.

Pakbin B, Allahyari S, Dibazar SP, et al. Effects of Probiotic Saccharomyces boulardii Supernatant on Viability, Nano-Mechanical Properties of Cytoplasmic Membrane and Pro-Inflammatory Gene Expression in Human Gastric Cancer AGS Cells. Int J Mol Sci. 2023;24(9):7945. Published 2023 Apr 27. doi:10.3390/ijms24097945.