Ölçme Hatalarındaki Etkilerin Düzeltilmesi
Özet
Maruziyet ölçümündeki hata için epidemiyolojik ilişki ölçümlerini düzeltecek çeşitli yöntemler mevcuttur. Bu yöntemler, hem birincil maruziyet değişkenini hem de kovaryantlardaki ölçme hataları için düzeltilmiş relatif risk ve güven aralıklarını sağlar. Her bir yöntem nadir olarak mükemmel bir şekilde karşılanan varsayımlar gerektirir. Örneğin, birçok yöntem hataların kesinlikle rastgele kişi-içi varyasyondan kaynaklandığını varsayar, fakat bunun besin alımı anketleri için doğru olma ihtimali düşüktür. Regresyon kalibasyonu gibi validasyon alt çalışmasını temel alan yöntemler, doğru ölçümün gerçekten doğru olduğunu (ya da en azından doğrunun yansız hesaplanmasını) varsayar. Bu sınırlamalara rağmen, bu düzeltme prosedürlerinin dikkatli kullanımı ölçme hatasının etkilerini tümüyle göz ardı eden analizerdense, beslenmeye bağlı faktörler ve hastalık arasındaki kantitatif ilişkileri daha iyi tahmin edilmesini sağlayacaktır.
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