The Role of Mi̇croRNAs in Covid-19 Infecti̇on

Abu-Izneid T, AlHajri N, Mohammad A, et al. IbrahimMicro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections. Journal of Advanced Research. 2021; 30, 133–145

Zhang H, Zhou P, Wei Y, Yue H, Wang Y, Hu M, et al. Histopathologic changes and SARS–CoV-2 immunostaining in the lung of a patient with COVID-19. Ann Intern Med. 2020. doi: https://doi.org/10.7326/M20-0533

Zou X, Chen K, Zou J, et al. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Front Med. 2020;14:185–192.

Wicik z, Eyileten C, Jakubik D, Simoes SN, Martins DC Jr, Pavao R, et al. Ace2 interaction networks in covid-19: A physiological framework for prediction of outcome in patients with cardiovascular risk factors. J Clin Med. 2020;9.

Bojkova, D.; Wagner, J.; Shumliakivska, M.; Aslan, G.; Saleem, U.; Hansen, A.; Luxan, G.; Guenther, S.; Pham, M.D.; Krishnan, J.; et al. SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes. bioRxiv 2020.

Pontecorvi G, Bellenghi M, Ortona E, Care A. Micrornas as new possible actors in gender disparities of covid-19 pandemic. Acta Physiol (Oxf). 2020;230:e13538.

Chauhan N, Jaggi M, Chauhan sC, Yallapu MM. Covid-19: fighting the invisible enemy with micrornas. Expert Rev Anti Infect Ther. 2020:1-9.

El-Nabi HS, Elhiti M, El-Sheekh M. A new approach for COVID-19 treatment by micro-RNA. Medical Hypotheses.2020;143, 110203

Pathak GA, Wendt fR, Goswami A, De Angelis f, Polimanti R. Ace2 netlas: In-silico functional characterization and drug-gene interactions of ace2 gene network to understand its potential involvement in covid-19 susceptibility. medRxiv. 2020.

Bartoszewski R, Dabrowski M, Jakiela B, Matalon s, Harrod Ks, sanak M, et al. sars-cov2 may regulate cellular responses through depletion of specific host mirnas. Am J Physiol Lung Cell Mol Physiol. 2020;319:L444-55.

Ma Y, Wang Ch, Xue M, Fu F, Zhang X, Li L, Yin L, Xu W, Feng L, Liu P. The Coronavirus Transmissible Gastroenteritis Virus Evades the Type I Interferon Response through IRE1α-Mediated Manipulation of the MicroRNA miR-30a-5p/SOCS1/3 Axis. J Virol. 2018;92:e00728-18.

Zhang s, Li J, Li J, Yang Y, Kang X, Li Y, et al. up-regulation of microrna-203 in influenza a virus infection inhibits viral replication by targeting dr1. sci Rep. 2018;8:6797.

Sacar Demirci MD, Adan A. Computational analysis of microrna-mediated interactions in sars-cov-2 infection. Peer J. 2020;8:e9369.

Fulzele s, sahay B, Yusufu I, Lee TJ, Sharma A, Kolhe R, et al. Covid-19 virulence in aged patients might be impacted by the host cellular micrornas abundance/profile. Aging Dis. 2020;11:509-22.

Khan MA, sany MRu, Islam Ms, Islam A. Epigenetic regulator mirna pattern differences among sars-cov, sars-cov-2, and sars-cov-2 world-wide isolates delineated the mystery behind the epic pathogenicity and distinct clinical characteristics of pandemic covid-19. Front Genet. 2020;11:765.

Barbu MG, Condrat CE, Thompson DC, Bugnar OL, Cretoiu D, Toader OD, et al. Microrna involvement in signaling pathways during viral infection. front Cell Dev Biol. 2020;8:143.

Aishwarya s, Gunasekaran K, Margret AA. Computational gene expression profiling in the exploration of biomarkers, non-coding functional rnas and drug perturbagens for covid19. J Biomol struct Dyn. 2020:1-16.

Rossato M, Affandi AJ, Thordardottir s, Wichers CGK, Cossu M, Broen JCA, et al. Association of microrna-618 expression with altered frequency and activation of plasmacytoid dendritic cells in patients with systemic sclerosis. Arthritis Rheumatol. 2017;69:1891-902.

Tribolet L, Kerr E, Cowled C, Bean AGD, Stewart CR, Dearnley M, et al. MicroRNA biomarkers for infectious diseases: from basic research to biosensing. Front Microbiol 2020;11. doi: https://doi.org/10.3389/

Wang M, Wey s, zhang Y, Ye R, Lee As. Role of the unfolded protein response regulator grp78/bip in development, cancer, and neurological disorders. Antioxid Redox signal. 2009;11:2307-16.

Balmeh N, Mahmoudi s, Mohammadi N, Karabedianhajiabadi A. Predicted therapeutic targets for covid-19 disease by inhibiting sarscov-2 and its related receptors. Inform Med unlocked. 2020;20:100407.

Arisan ED, Dart A, Grant GH, Arisan s, Cuhadaroglu s, Lange s, et al. The prediction of mirnas in sars-cov-2 genomes: Hsa-mir databases identify 7 key mirs linked to host responses and virus pathogenicity-related kegg pathways significant for comorbidities. Viruses. 2020;12.

Liu z, Wang J, Xu Y, Guo M, Mi K, Xu R, et al. Implications of the virus-encoded mirna and host mirna in the pathogenicity of sars-cov-2. Arxiv:2004.04874v1 [q-bio. Gn]. 2020.

Yousefi H, Poursheikhani A, Bahmanpour z, Vatanmakanian M, Taheri M, Mashouri L, et al. sars-cov infection crosstalk with human host cell noncoding-rna machinery: An in-silico approach. Biomed Pharmacother. 2020;130:110548.

Arora s, singh P, Dohare R, Jha R, Ali syed M. unravelling host-pathogen interactions: Cerna network in sars-cov-2 infection (covid19). Gene. 2020;762:145057.

Bertolazzi G, Cipollina C, Benos PV, Tumminello M, Coronnello C. Mir-1207-5p can contribute to dysregulation of inflammatory response in covid19 via targeting sars-cov-2 rna. front Cell Infect Microbiol. 2020;10:586592.

Srivastava R, Daulatabad sV, srivastava M, Janga sC. Role of sars-cov-2 in altering the RNA-binding protein and mirna-directed posttranscriptional regulatory networks in humans.

Int J Mol sci. 2020;21.

Abu-Izneid T, AlHajri N, Mohammad A, et al. IbrahimMicro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections. Journal of Advanced Research. 2021; 30, 133–145

Zhang H, Zhou P, Wei Y, Yue H, Wang Y, Hu M, et al. Histopathologic changes and SARS–CoV-2 immunostaining in the lung of a patient with COVID-19. Ann Intern Med. 2020. doi: https://doi.org/10.7326/M20-0533

Zou X, Chen K, Zou J, et al. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Front Med. 2020;14:185–192.

Wicik z, Eyileten C, Jakubik D, Simoes SN, Martins DC Jr, Pavao R, et al. Ace2 interaction networks in covid-19: A physiological framework for prediction of outcome in patients with cardiovascular risk factors. J Clin Med. 2020;9.

Bojkova, D.; Wagner, J.; Shumliakivska, M.; Aslan, G.; Saleem, U.; Hansen, A.; Luxan, G.; Guenther, S.; Pham, M.D.; Krishnan, J.; et al. SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes. bioRxiv 2020.

Pontecorvi G, Bellenghi M, Ortona E, Care A. Micrornas as new possible actors in gender disparities of covid-19 pandemic. Acta Physiol (Oxf). 2020;230:e13538.

Chauhan N, Jaggi M, Chauhan sC, Yallapu MM. Covid-19: fighting the invisible enemy with micrornas. Expert Rev Anti Infect Ther. 2020:1-9.

El-Nabi HS, Elhiti M, El-Sheekh M. A new approach for COVID-19 treatment by micro-RNA. Medical Hypotheses.2020;143, 110203

Pathak GA, Wendt fR, Goswami A, De Angelis f, Polimanti R. Ace2 netlas: In-silico functional characterization and drug-gene interactions of ace2 gene network to understand its potential involvement in covid-19 susceptibility. medRxiv. 2020.

Bartoszewski R, Dabrowski M, Jakiela B, Matalon s, Harrod Ks, sanak M, et al. sars-cov2 may regulate cellular responses through depletion of specific host mirnas. Am J Physiol Lung Cell Mol Physiol. 2020;319:L444-55.

Ma Y, Wang Ch, Xue M, Fu F, Zhang X, Li L, Yin L, Xu W, Feng L, Liu P. The Coronavirus Transmissible Gastroenteritis Virus Evades the Type I Interferon Response through IRE1α-Mediated Manipulation of the MicroRNA miR-30a-5p/SOCS1/3 Axis. J Virol. 2018;92:e00728-18.

Zhang s, Li J, Li J, Yang Y, Kang X, Li Y, et al. up-regulation of microrna-203 in influenza a virus infection inhibits viral replication by targeting dr1. sci Rep. 2018;8:6797.

Sacar Demirci MD, Adan A. Computational analysis of microrna-mediated interactions in sars-cov-2 infection. Peer J. 2020;8:e9369.

Fulzele s, sahay B, Yusufu I, Lee TJ, Sharma A, Kolhe R, et al. Covid-19 virulence in aged patients might be impacted by the host cellular micrornas abundance/profile. Aging Dis. 2020;11:509-22.

Khan MA, sany MRu, Islam Ms, Islam A. Epigenetic regulator mirna pattern differences among sars-cov, sars-cov-2, and sars-cov-2 world-wide isolates delineated the mystery behind the epic pathogenicity and distinct clinical characteristics of pandemic covid-19. Front Genet. 2020;11:765.

Barbu MG, Condrat CE, Thompson DC, Bugnar OL, Cretoiu D, Toader OD, et al. Microrna involvement in signaling pathways during viral infection. front Cell Dev Biol. 2020;8:143.

Aishwarya s, Gunasekaran K, Margret AA. Computational gene expression profiling in the exploration of biomarkers, non-coding functional rnas and drug perturbagens for covid19. J Biomol struct Dyn. 2020:1-16.

Rossato M, Affandi AJ, Thordardottir s, Wichers CGK, Cossu M, Broen JCA, et al. Association of microrna-618 expression with altered frequency and activation of plasmacytoid dendritic cells in patients with systemic sclerosis. Arthritis Rheumatol. 2017;69:1891-902.

Tribolet L, Kerr E, Cowled C, Bean AGD, Stewart CR, Dearnley M, et al. MicroRNA biomarkers for infectious diseases: from basic research to biosensing. Front Microbiol 2020;11. doi: https://doi.org/10.3389/

Wang M, Wey s, zhang Y, Ye R, Lee As. Role of the unfolded protein response regulator grp78/bip in development, cancer, and neurological disorders. Antioxid Redox signal. 2009;11:2307-16.

Balmeh N, Mahmoudi s, Mohammadi N, Karabedianhajiabadi A. Predicted therapeutic targets for covid-19 disease by inhibiting sarscov-2 and its related receptors. Inform Med unlocked. 2020;20:100407.

Arisan ED, Dart A, Grant GH, Arisan s, Cuhadaroglu s, Lange s, et al. The prediction of mirnas in sars-cov-2 genomes: Hsa-mir databases identify 7 key mirs linked to host responses and virus pathogenicity-related kegg pathways significant for comorbidities. Viruses. 2020;12.

Liu z, Wang J, Xu Y, Guo M, Mi K, Xu R, et al. Implications of the virus-encoded mirna and host mirna in the pathogenicity of sars-cov-2. Arxiv:2004.04874v1 [q-bio. Gn]. 2020.

Yousefi H, Poursheikhani A, Bahmanpour z, Vatanmakanian M, Taheri M, Mashouri L, et al. sars-cov infection crosstalk with human host cell noncoding-rna machinery: An in-silico approach. Biomed Pharmacother. 2020;130:110548.

Arora s, singh P, Dohare R, Jha R, Ali syed M. unravelling host-pathogen interactions: Cerna network in sars-cov-2 infection (covid19). Gene. 2020;762:145057.

Bertolazzi G, Cipollina C, Benos PV, Tumminello M, Coronnello C. Mir-1207-5p can contribute to dysregulation of inflammatory response in covid19 via targeting sars-cov-2 rna. front Cell Infect Microbiol. 2020;10:586592.

Srivastava R, Daulatabad sV, srivastava M, Janga sC. Role of sars-cov-2 in altering the RNA-binding protein and mirna-directed posttranscriptional regulatory networks in humans.

Int J Mol sci. 2020;21.