Metal Organik Çerçeveler
Özet
Metal iyonları veya kümelerinin çok dişli organik bağlayıcılarla kovalan bağlanarak oluşturduğu Metal Organik Çerçeveler (MOF) geniş yüzey alanı, gözenekli yapı, yüksek adsorpsiyon kapasitesi, termal ve mekanik stabilite, düşük toksisite gibi özelliklere sahiptir. Gaz depolama, saflaştırma, süperkapasitör, kataliz, adsorpsiyon gibi kullanımları bulunmaktadır. Günümüzde koordinasyon modülasyonu, yüzey kaplama gibi tekniklerle modifiye edilen nanoMOF ve biyoMOF tiplerinden etken madde enkapsülasyonu ile taşıyıcı sistem ve hedeflendirme amacıyla yararlanılmaktadır. Biyomedikal alanda fototerapi, teranostik sistem, biyokataliz, görüntülemede kontrast ajanı, biyosensör gibi kullanımları bulunmaktadır. MOF özelliklerinin incelenmesinde FTIR, XRD, TEM, SEM, zeta potansiyeli gibi tekniklerin yanı sıra spektroskopik yöntemler ve ELİSA gibi testlerden de yararlanılmaktadır.
Referanslar
Rojas S, Arenas-Vivo A, Horcajada P. Metal-organic frameworks: A novel platform for combined advanced therapies. Coordination Chemistry Reviews. 2019; 388: 202-226. https://doi.org/10.1016/j.ccr.2019.02.032
Pettinari C, Marchetti F, Mosca N, et al. Application of metal-organic frameworks. Polymer International. 2017; 66: 731-744. DOI:10.1002/pi.5315
Nabipour H, Mozafari M, Hu Y. Chapter 1: Nomenclature of MOFs. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.1-9. https://doi.org/10.1016/B978--0-12-816984-1.00002-0
Barbosa JS, Figueira F, Braga SS, Filipe A. Almeida Paz. 2020. Chapter 4: Metal-organic frameworks for biomedical applications: The case of functional ligands. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.69-92. https://doi.org/10.1016/B978-0-12-816984-1.00005-6
Lawson HD, Walton SP, Chan C. Metal organic frameworks for drug delivery: A design perspective. ACS Applied Materials and Interfaces. 2021; 13: 7004-7020. https://dx.doi.org/10.1021/acsami.1c01089
Mendes RF, Figueira F, Leite JP, et al. Metal–organic frameworks: a future toolbox for biomedicine? Chemical Society Reviews. 2020; 49 (24): 9121-9153. https://doi.org/10.1039/D0CS00883D
Zhang X, Chen Z, Liu X, et al. A historical overview of the activation and porosity of metal-organic frameworks. Chemical Society Reviews. 2020; 49: 7406- 7427. https://doi.org/10.1039/D0CS00997K
McGuire CV, Forgan RS. The surface chemistry of metal-organic frameworks. ChemComm. 2015; 51: 5159. DOI: 10.1039/c4cc04458d
Wang Y, Yan J, Wen N. Metal organic frameworks for stimuli-responsive drug delivery. Biomaterials. 2020; 230: 11969. https://doi.org/10.1016/j.biomaterials.2019.119619
Nasrollahi M, Nabipour H, Valizadeh N, Mozafari M. Chapter 5: The role of flexibility in MOFs. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.93-110. https://doi.org/10.1016/B978-0-12-816984-1.00006-8
Wang HS, Wang YH, Ding Y. Development of biological metal–organic frameworks designed for biomedical applications: from bio-sensing/bio-imaging to disease treatment. Nanoscale Advances. 2020; 2: 3788-3797. https://doi.org/10.1039/D0NA00557F
Liu J, Li Y, Lou Z. Recent advancements in MOF/Biomass and Bio-MOF multifunctional aaterials: A review. Sustainability. 2022; 14: 5768. https://doi.org/10.3390/su14105768
Wang S, Wahiduzzaman W, Davis L, et al. A robust zirconium amino acid metal-organic framework for proton conduction. Nature Communications. 2018; 9: 4937. https://doi.org/10.1038/s41467-018-07414-4
Jeong GS, Kathalikkattil AC, Babu R, et al. Cycloaddition of CO2 with epoxides by using an amino-acid-based Cu(II)-tryptophan MOF catalyst. Chinese Journal of Catalysis. 2018; 39: 63-70. https://doi.org/10.1016/S1872-2067(17)62916-4
Shoueir K, Wassel AR, Ahmed MK, et al. Encapsulation of extremely stable polyaniline onto Bio-MOF: Photo-activated antimicrobial and depletion of ciprofloxacin from aqueous solutions. Journal of Photochemistry and Photobiology A: Chemistry. 2020; 400: 112703. https://doi.org/10.1016/j.jphotochem.2020.112703
Bhadra BN, Jhung SH. Adsorptive removal of wide range of pharmaceuticals and personal care products from water using bio-MOF-1 derived porous carbon. Microporous and Mesoporous Materials. 2018; 270: 102-108. https://doi.org/10.1016/j.micromeso.2018.05.005
Azhar MR, Vijay P, Tade MO, et al. Submicron sized water-stable metal organic framework (bio-MOF-11) for catalytic degradation of pharmaceuticals and personal care products. Chemosphere. 2018; 196: 105e114. https://doi.org/10.1016/j.chemosphere.2017.12.164
Anderson SL, Boyd PG, Gladysiak A, et al. Nucleobase pairing and photodimerization in a biologically derived metal-organic framework nanoreactor. Nature Communications. 2019; 10: 1612. https://doi.org/10.1038/s41467-019-09486-2
Hidalgo T, Cooper L, Gorman M. Crystal structure dependent in vitro antioxidant activity of biocompatible calcium gallate MOFs. Journal of Materials Chemistry B. 2017;5:2813. https://doi.org/10.1039/C6TB03101C
Au KM, Satterlee A, Min Y, et al. Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: Turning a bone antiresorptive agent into an anticancer therapeutic. Biomaterials. 2016;82:178-93. DOI: 10.1016/j.biomaterials.2015.12.018
Tamames-Tabar C, Imbuluzqueta E, Guillou N, et al. A Zn azelate MOF: combining antibacterial effect. CrystEngComm. 2015; 17: 456-462. https://doi.org/10.1039/C4CE00885E
Levine DJ, Runčevski T, Kapelewski MT, et al. Olsalazine-based metal-organic frameworks as biocompatible platforms for H2 adsorption and drug delivery. Journal of the American Chemical Society. 2016; 138(32):10143-10150. https://doi.org/10.1021/jacs.6b03523
Su H, Sun F, Jia J, et al. A highly porous medical metal-organic framework constructed from bioactive curcumin. Chemical Communications. 2015; 51: 5774-5777. https://doi.org/10.1039/C4CC10159F
Pinto RV, Antunes F, Pires J, et al. Vitamin B3 metal-organic frameworks as potential delivery vehicles for therapeutic nitric oxide. Acta Biomaterialia. 2017; 51: 66-74. https://doi.org/10.1016/j.actbio.2017.01.039.
Wang J, Fan Y, Tan Y, et al. Porphyrinic metal-organic framework PCN-224 nanoparticles for near-infrared-induced attenuation of aggregation and neurotoxicity of alzheimer's amyloid-β peptide. ACS Applied Materials and Interfaces. 2018; 10(43): 36615-36621. https://doi.org/10.1021/acsami.8b15452
Hu X, Wang C, Wang L, et al. Nanoporous CD-MOF particles with uniform and inhalable size for pulmonary delivery of budesonide. International Journal of Pharmaceutics. 2019;564:153-161. https://doi.org/10.1016/j.ijpharm.2019.04.030.
Ding M, Liu W, Gref R. Nanoscale MOFs: From synthesis to drug delivery and theranostics applications. Advanced Drug Delivery Reviews. 2022; 190: 114496. https://doi.org/10.1016/j.addr.2022.114496
Kumar S, Jain S, Nehra M, et al. Green synthesis of metal–organic frameworks: A state-of-the-art review of potential environmental and medical applications. Coordination Chemistry Reviews. 2020; 420: 213407. https://doi.org/10.1016/j.ccr.2020.213407
Rabiee N, Atarod M, Tavakolizadeh M, et al. Green metal-organic frameworks (MOFs) for biomedical applications. Microporous and Mesoporous Materials. 2022; 335: 111670. https://doi.org/10.1016/j.micromeso.2021.111670
Salehipour M, Rezaei S, Rezaei M, et al. Opportunities and challenges in biomedical applications of metal-organic frameworks. Journal of Inorganic and Organometallic Polymers. 2021; 31: 4443-4462. https://doi.org/10.1007/s10904-021-02118-7
Ekinci EK. Yeni nesil MIL-101 malzemesi sentez ve karakterizasyon çalışmaları. Gazi Üniversitesi Fen Bilimleri Dergisi Part C: Tasarım ve Teknoloji. 2017; 5(4): 179-185. DOI: 10.29109/http-gujsc-gazi-edu-tr.306699
Bieniek A, Terzyk AP, Wi´sniewski M, et al. MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives. Progress in Materials Science. 2021; 117: 100743. https://doi.org/10.1016/j.pmatsci.2020.100743
Vaidya LB, Nadar SS, Rathod VK. Chapter 22: Metal-organic frameworks (MOFs) for enzyme immobilization. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.491-523. https://doi.org/10.1016/B978-0-12-816984-1.00024-X
Majewski MB, Howarth AJ, Li P, et al. Enzyme encapsulation in metal–organic frameworks for applications in catalysis, CrystEngComm. 2017;19 (29): 4082-4091. DOI: 10.1039/c7ce00022g
Riccò R, Liang W, Li S, et al. Metal-organic frameworks for cell and virus biology: A perspective. ACS Nano. 2018; 12 (1): 13-23. DOI: 10.1021/acsnano.7b08056
Chen L, Peng J, Wang F. ZnO nanorods/Fe3O4-graphene oxide/metal-organic framework nanocomposite: recyclable and robust photocatalyst for degradation of pharmaceutical pollutants. Environmental Science and Pollution Research. 2021; 28:21799-21811. https://doi.org/10.1007/s11356-020-12253-2
Han A, Wang B, Kumar A, et al. Recent advances for MOF-derived carbon-supported single-atom catalysts. Small Methods. 2019; 3: 1800471. https://doi.org/10.1002/smtd.201800471.
Rasheed T, Bilal M, Hassan AA. Environmental threatening concern and efficient removal of pharmaceutically active compounds using metal-organic frameworks as adsorbents. Environmental Research. 2020; 185: 109436. https://doi.org/10.1016/j.envres.2020.109436
Chen D, Chen C, Shen W, et al. MOF-derived magnetic porous carbon-based sorbent: Synthesis, characterization, and adsorption behavior of organic micropollutants. Advanced Powder Technology. 2017; 28 (7):1769-1779. DOI:10.1016/j.apt.2017.04.018
Wang X, Qiaoqin L, Nana Y, et al. Hydrothermal synthesis of NiCo-based bimetal-organic frameworks as electrode materials for supercapacitors. Journal of Solid State Chemistry. 2019; 270: 370-378. https://doi.org/10.1016/j.jssc.2018.11.038
Wyszogrodzka-Gaweł G, Dorożyński P, Giovagnoli S, et al. An inhalable theranostic system for local tuberculosis treatment containing an isoniazid loaded metal organic framework Fe-MIL-101-NH2-From raw MOF to drug delivery system. Pharmaceutics. 2019;11(12):687. doi: 10.3390/pharmaceutics11120687.
Ferna´ndez-Paz C, Rojas S, Salcedo-Abraira P. Metal-organic framework microsphere formulation for pulmonary administration. ACS Applied Materials and Interfaces. 2020; 12: 25676–25682. 2
Li X, Chandler M, Avila YI, et al. Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells. International Journal of Pharmaceutics: X. 2023; 5: 100161. https://doi.org/10.1016/j.ijpX.2023.100161
Christodoulou I, Lyu P, Soares CV, et al. Nanoscale iron-based metal-organic frameworks: Incorporation of functionalized drugs and degradation in biological media. International Journal of Molecular Sciences. 2023; 24: 3362-3380. https://doi.org/10.3390/ijms24043362
Zeng L, Huang L, Han G. Dye doped metal-organic frameworks for enhanced phototherapy. Advanced Drug Delivery Reviews. 2022;189:114479. https://doi.org/10.1016/j.addr.2022.114479
Samui A, Sahu SK. Chapter 13: Characterizations of MOFs for biomedical application. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p. 277-295. https://doi.org/10.1016/B978-0-12-816984-1.00015-9
Ettlinger R, Lächelt U, Gref R, et al. Toxicity of metal-organic framework nanoparticles: from essential analyses to potential applications. Chemical Society Reviews. 2022; 51: 464-484. https://doi.org/10.1039/D3CS90014D
Ettlinger R, Lächelt U, Gref R, et al. Correction:Toxicity of metal-organic framework nanoparticles: from essential analyses to potential applications. Chemical Society Reviews.2022;51:464-484. https://doi.org/10.1039/D3CS90014B
Referanslar
Rojas S, Arenas-Vivo A, Horcajada P. Metal-organic frameworks: A novel platform for combined advanced therapies. Coordination Chemistry Reviews. 2019; 388: 202-226. https://doi.org/10.1016/j.ccr.2019.02.032
Pettinari C, Marchetti F, Mosca N, et al. Application of metal-organic frameworks. Polymer International. 2017; 66: 731-744. DOI:10.1002/pi.5315
Nabipour H, Mozafari M, Hu Y. Chapter 1: Nomenclature of MOFs. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.1-9. https://doi.org/10.1016/B978--0-12-816984-1.00002-0
Barbosa JS, Figueira F, Braga SS, Filipe A. Almeida Paz. 2020. Chapter 4: Metal-organic frameworks for biomedical applications: The case of functional ligands. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.69-92. https://doi.org/10.1016/B978-0-12-816984-1.00005-6
Lawson HD, Walton SP, Chan C. Metal organic frameworks for drug delivery: A design perspective. ACS Applied Materials and Interfaces. 2021; 13: 7004-7020. https://dx.doi.org/10.1021/acsami.1c01089
Mendes RF, Figueira F, Leite JP, et al. Metal–organic frameworks: a future toolbox for biomedicine? Chemical Society Reviews. 2020; 49 (24): 9121-9153. https://doi.org/10.1039/D0CS00883D
Zhang X, Chen Z, Liu X, et al. A historical overview of the activation and porosity of metal-organic frameworks. Chemical Society Reviews. 2020; 49: 7406- 7427. https://doi.org/10.1039/D0CS00997K
McGuire CV, Forgan RS. The surface chemistry of metal-organic frameworks. ChemComm. 2015; 51: 5159. DOI: 10.1039/c4cc04458d
Wang Y, Yan J, Wen N. Metal organic frameworks for stimuli-responsive drug delivery. Biomaterials. 2020; 230: 11969. https://doi.org/10.1016/j.biomaterials.2019.119619
Nasrollahi M, Nabipour H, Valizadeh N, Mozafari M. Chapter 5: The role of flexibility in MOFs. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.93-110. https://doi.org/10.1016/B978-0-12-816984-1.00006-8
Wang HS, Wang YH, Ding Y. Development of biological metal–organic frameworks designed for biomedical applications: from bio-sensing/bio-imaging to disease treatment. Nanoscale Advances. 2020; 2: 3788-3797. https://doi.org/10.1039/D0NA00557F
Liu J, Li Y, Lou Z. Recent advancements in MOF/Biomass and Bio-MOF multifunctional aaterials: A review. Sustainability. 2022; 14: 5768. https://doi.org/10.3390/su14105768
Wang S, Wahiduzzaman W, Davis L, et al. A robust zirconium amino acid metal-organic framework for proton conduction. Nature Communications. 2018; 9: 4937. https://doi.org/10.1038/s41467-018-07414-4
Jeong GS, Kathalikkattil AC, Babu R, et al. Cycloaddition of CO2 with epoxides by using an amino-acid-based Cu(II)-tryptophan MOF catalyst. Chinese Journal of Catalysis. 2018; 39: 63-70. https://doi.org/10.1016/S1872-2067(17)62916-4
Shoueir K, Wassel AR, Ahmed MK, et al. Encapsulation of extremely stable polyaniline onto Bio-MOF: Photo-activated antimicrobial and depletion of ciprofloxacin from aqueous solutions. Journal of Photochemistry and Photobiology A: Chemistry. 2020; 400: 112703. https://doi.org/10.1016/j.jphotochem.2020.112703
Bhadra BN, Jhung SH. Adsorptive removal of wide range of pharmaceuticals and personal care products from water using bio-MOF-1 derived porous carbon. Microporous and Mesoporous Materials. 2018; 270: 102-108. https://doi.org/10.1016/j.micromeso.2018.05.005
Azhar MR, Vijay P, Tade MO, et al. Submicron sized water-stable metal organic framework (bio-MOF-11) for catalytic degradation of pharmaceuticals and personal care products. Chemosphere. 2018; 196: 105e114. https://doi.org/10.1016/j.chemosphere.2017.12.164
Anderson SL, Boyd PG, Gladysiak A, et al. Nucleobase pairing and photodimerization in a biologically derived metal-organic framework nanoreactor. Nature Communications. 2019; 10: 1612. https://doi.org/10.1038/s41467-019-09486-2
Hidalgo T, Cooper L, Gorman M. Crystal structure dependent in vitro antioxidant activity of biocompatible calcium gallate MOFs. Journal of Materials Chemistry B. 2017;5:2813. https://doi.org/10.1039/C6TB03101C
Au KM, Satterlee A, Min Y, et al. Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: Turning a bone antiresorptive agent into an anticancer therapeutic. Biomaterials. 2016;82:178-93. DOI: 10.1016/j.biomaterials.2015.12.018
Tamames-Tabar C, Imbuluzqueta E, Guillou N, et al. A Zn azelate MOF: combining antibacterial effect. CrystEngComm. 2015; 17: 456-462. https://doi.org/10.1039/C4CE00885E
Levine DJ, Runčevski T, Kapelewski MT, et al. Olsalazine-based metal-organic frameworks as biocompatible platforms for H2 adsorption and drug delivery. Journal of the American Chemical Society. 2016; 138(32):10143-10150. https://doi.org/10.1021/jacs.6b03523
Su H, Sun F, Jia J, et al. A highly porous medical metal-organic framework constructed from bioactive curcumin. Chemical Communications. 2015; 51: 5774-5777. https://doi.org/10.1039/C4CC10159F
Pinto RV, Antunes F, Pires J, et al. Vitamin B3 metal-organic frameworks as potential delivery vehicles for therapeutic nitric oxide. Acta Biomaterialia. 2017; 51: 66-74. https://doi.org/10.1016/j.actbio.2017.01.039.
Wang J, Fan Y, Tan Y, et al. Porphyrinic metal-organic framework PCN-224 nanoparticles for near-infrared-induced attenuation of aggregation and neurotoxicity of alzheimer's amyloid-β peptide. ACS Applied Materials and Interfaces. 2018; 10(43): 36615-36621. https://doi.org/10.1021/acsami.8b15452
Hu X, Wang C, Wang L, et al. Nanoporous CD-MOF particles with uniform and inhalable size for pulmonary delivery of budesonide. International Journal of Pharmaceutics. 2019;564:153-161. https://doi.org/10.1016/j.ijpharm.2019.04.030.
Ding M, Liu W, Gref R. Nanoscale MOFs: From synthesis to drug delivery and theranostics applications. Advanced Drug Delivery Reviews. 2022; 190: 114496. https://doi.org/10.1016/j.addr.2022.114496
Kumar S, Jain S, Nehra M, et al. Green synthesis of metal–organic frameworks: A state-of-the-art review of potential environmental and medical applications. Coordination Chemistry Reviews. 2020; 420: 213407. https://doi.org/10.1016/j.ccr.2020.213407
Rabiee N, Atarod M, Tavakolizadeh M, et al. Green metal-organic frameworks (MOFs) for biomedical applications. Microporous and Mesoporous Materials. 2022; 335: 111670. https://doi.org/10.1016/j.micromeso.2021.111670
Salehipour M, Rezaei S, Rezaei M, et al. Opportunities and challenges in biomedical applications of metal-organic frameworks. Journal of Inorganic and Organometallic Polymers. 2021; 31: 4443-4462. https://doi.org/10.1007/s10904-021-02118-7
Ekinci EK. Yeni nesil MIL-101 malzemesi sentez ve karakterizasyon çalışmaları. Gazi Üniversitesi Fen Bilimleri Dergisi Part C: Tasarım ve Teknoloji. 2017; 5(4): 179-185. DOI: 10.29109/http-gujsc-gazi-edu-tr.306699
Bieniek A, Terzyk AP, Wi´sniewski M, et al. MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives. Progress in Materials Science. 2021; 117: 100743. https://doi.org/10.1016/j.pmatsci.2020.100743
Vaidya LB, Nadar SS, Rathod VK. Chapter 22: Metal-organic frameworks (MOFs) for enzyme immobilization. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p.491-523. https://doi.org/10.1016/B978-0-12-816984-1.00024-X
Majewski MB, Howarth AJ, Li P, et al. Enzyme encapsulation in metal–organic frameworks for applications in catalysis, CrystEngComm. 2017;19 (29): 4082-4091. DOI: 10.1039/c7ce00022g
Riccò R, Liang W, Li S, et al. Metal-organic frameworks for cell and virus biology: A perspective. ACS Nano. 2018; 12 (1): 13-23. DOI: 10.1021/acsnano.7b08056
Chen L, Peng J, Wang F. ZnO nanorods/Fe3O4-graphene oxide/metal-organic framework nanocomposite: recyclable and robust photocatalyst for degradation of pharmaceutical pollutants. Environmental Science and Pollution Research. 2021; 28:21799-21811. https://doi.org/10.1007/s11356-020-12253-2
Han A, Wang B, Kumar A, et al. Recent advances for MOF-derived carbon-supported single-atom catalysts. Small Methods. 2019; 3: 1800471. https://doi.org/10.1002/smtd.201800471.
Rasheed T, Bilal M, Hassan AA. Environmental threatening concern and efficient removal of pharmaceutically active compounds using metal-organic frameworks as adsorbents. Environmental Research. 2020; 185: 109436. https://doi.org/10.1016/j.envres.2020.109436
Chen D, Chen C, Shen W, et al. MOF-derived magnetic porous carbon-based sorbent: Synthesis, characterization, and adsorption behavior of organic micropollutants. Advanced Powder Technology. 2017; 28 (7):1769-1779. DOI:10.1016/j.apt.2017.04.018
Wang X, Qiaoqin L, Nana Y, et al. Hydrothermal synthesis of NiCo-based bimetal-organic frameworks as electrode materials for supercapacitors. Journal of Solid State Chemistry. 2019; 270: 370-378. https://doi.org/10.1016/j.jssc.2018.11.038
Wyszogrodzka-Gaweł G, Dorożyński P, Giovagnoli S, et al. An inhalable theranostic system for local tuberculosis treatment containing an isoniazid loaded metal organic framework Fe-MIL-101-NH2-From raw MOF to drug delivery system. Pharmaceutics. 2019;11(12):687. doi: 10.3390/pharmaceutics11120687.
Ferna´ndez-Paz C, Rojas S, Salcedo-Abraira P. Metal-organic framework microsphere formulation for pulmonary administration. ACS Applied Materials and Interfaces. 2020; 12: 25676–25682. 2
Li X, Chandler M, Avila YI, et al. Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells. International Journal of Pharmaceutics: X. 2023; 5: 100161. https://doi.org/10.1016/j.ijpX.2023.100161
Christodoulou I, Lyu P, Soares CV, et al. Nanoscale iron-based metal-organic frameworks: Incorporation of functionalized drugs and degradation in biological media. International Journal of Molecular Sciences. 2023; 24: 3362-3380. https://doi.org/10.3390/ijms24043362
Zeng L, Huang L, Han G. Dye doped metal-organic frameworks for enhanced phototherapy. Advanced Drug Delivery Reviews. 2022;189:114479. https://doi.org/10.1016/j.addr.2022.114479
Samui A, Sahu SK. Chapter 13: Characterizations of MOFs for biomedical application. Mozafari M (ed.) Metal-Organic Frameworks for Biomedical Applications içinde. Woodhead Publishing, Elsevier Inc.; 2020. p. 277-295. https://doi.org/10.1016/B978-0-12-816984-1.00015-9
Ettlinger R, Lächelt U, Gref R, et al. Toxicity of metal-organic framework nanoparticles: from essential analyses to potential applications. Chemical Society Reviews. 2022; 51: 464-484. https://doi.org/10.1039/D3CS90014D
Ettlinger R, Lächelt U, Gref R, et al. Correction:Toxicity of metal-organic framework nanoparticles: from essential analyses to potential applications. Chemical Society Reviews.2022;51:464-484. https://doi.org/10.1039/D3CS90014B
