Erektil Disfonksiyon ve Prematür Ejekülasyon
Özet
Erektil disfonksiyon’un (ED) Amerikan Psikiyatri Birliği’nin DSM-5 tanı kılavuzuna göre tanımı; en az 6 ay süreli olmak üzere cinsel ilişkilerin tamamında veya neredeyse tamamında cinsel birliktelik sonuçlanana kadar sertleşmeyi sağlayamama ve devam ettirememe veya yetersiz sertleşmenin olmasıdır. Prematür ejakülasyon kişiye ve partnere göre farklılık içerebilen bir durum olduğundan tanımlaması zordur. Tanımlamaların çoğu kanıta dayalı değildir. Kişi ve partnere bağlı değişkenlik gösterebilir.
Referanslar
AmericaPsychiatricAssociation. Diagnosticand Statistical Manuel of MentalDisordersFifth Edition. Arlington, VA. 2013.
Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotenceanditsmedicalandpsychosocialcorrelates: results of the Massachusetts Male AgingStudy. TheJournal of urology. 1994;151(1):54– 61.
Braun M, Wassmer G, Klotz T, Reifenrath B, Mathers M, Engelmann U. Epidemiology of erectiledysfunction: results of the ‘Cologne Male Survey’. International journal of impotenceresearch. 2000;12(6):305–11.
Akkus E, Kadioglu A, Esen A, Doran S, Ergen A, Anafarta K, et al. Prevalenceandcorrelates of erectiledysfunction in Turkey: a population-basedstudy. Europeanurology. 2002;41(3):298–304.
Kaplan H. ThePsychosexual Evaluation. Kaplan HS(ed). The Evaluation of SexualDisorders. New York, Brunne/Mazelinc. 1983/23–25.
Shamloul R, Ghanem H. Erectiledysfunction. Lancet. 2013;381 (9861):153–65.
Simopoulos EF, Trinidad AC. Male erectiledysfunction: integratingpsychopharmacologyandpsychotherapy. General hospitalpsychiatry. 2013;35(1):33–8.
Melnik T, Abdo C.G. Psychogenicerectiledysfunction. Comparativestudy of threetherapeuticapproaches. J SexMaritalTher. 2005;31:243–255.
Kapella, Olaf et Stahlhart: MännerunderektileDysfunktion Publisher: Wien: Ö sterreichischesInstitutfü r Familienforschung, [2003]
Stief, C. G.:ErektileDysfunktion: DiagnostikundTherapie, Berlin; New York: Springer, c1997
Thomas Meißner: Werschlankbleibt, hält im AlterseinenTestosteronSpiegel. Der Testosteron-Spiegel sinktbeiMännernnichtzwangsläufi g mit dem Alter. Aber: VieleKomorbiditätengehen mit Testosteronmangeleinher. In: ÄrzteZeitungvom 27. April 2010. AWMF S1-Leitlinie ErektileDysfunkti on (PDF; 1 MB)
I. Motil, I. Kubis et al.:Treatment of VasculogenicErectileDysfunctionwith Piezowave2 Device. In: Advances in SexualMedicine. Band 6, Nr. 2, April 2016, doi:10.4236/asm.2016.62002
EuropäischeGesundheitsbehörde (EMA): Europeanpublicassessmentreport (EPAR) forSpedra - avanafi l. Auf: ema.europa.eu abgerufen am 11. Februar 2014.
DeutscheApothekerZeitung (DAZ): ErektileDysfunktion - Neuer PDE5- HemmerAvanafi l Auf: deutsche-apotheker-zeitung.deabgerufen am 11. Februar 2014.
K. E. HatzimouraƟdis, E. Wespe et al.:Guidelines on malesexualdysfunction: erectiledysfuntionandprematureejaculation. In: EuropeanUrology. 2010, Bd. 57, Nr. 5, S. 804–814, PMID 20189712, doi:10.1016/j. eururo.2010.02.020 (PDF-Datei, VollständigeFassung der Leitlinien).
Waldinger MD, Hengeveld MW, Zwinderman AH. Paroxetinetreatment of prematureejaculation: a double-blind, randomized, placebo-controlledstudy. Am J Psychiatry. 1994;151(9):1377-9
Waldinger MD, Schweitzer DH. Theuse of oldandrecent DSM definitions of prematureejaculation in observationalstudies: a contributiontothepresentdebatefor a newclassification of PE in the DSM-V. J SexMed. 2008;5(5):1079- 87.
Serefoglu EC, Yaman O, Cayan S ve ark. Prevalence of thecomplaint of ejaculatingprematurelyandthefourprematureejaculationsyndromes: resultsfromtheTurkishSociety of AndrologySexualHealthSurvey. J SexMed. 2011;8(2):540- 8.
Waldinger MD, Quinn P, Dilleen M ve ark. A multinationalpopulationsurvey of intravaginalejaculationlatency time. J SexMed. 2005;2(4):492-7.
Jannini EA, Lombardo F, Lenzi A. Correlationbetweenejaculatoryanderectiledysfunction. Int J Androl. 2005;28 Suppl2:40-5
Screponi E, Carosa E, DiStasi SM ve ark. Prevalence of chronicprostatitis in men withprematureejaculation. Urology. 2001;58(2):198-202.
Carani C, Isidori AM, Granata A ve ark. Multicenterstudy on theprevalence of sexualsymptoms in malehypo- andhyperthyroidpatients. J ClinEndocrinolMetab. 2005;90(12):6472-9.
Hartmann U, Schedlowski M, Krüger TH. Cognitiveandpartner-relatedfactors in rapidejaculation: differencesbetweendysfunctionalandfunctional men. World J Urol. 2005;23(2):93-101.
Chekuri V, Gerber D, Brodie A, Krishnadas R. Prematureejaculationandothersexualdysfunctions in opiatedependent men receivingmethadonesubstitutiontreatment. AddictBehav. 2012;37(1):124-6.
Adson DE, Kotlyar M. Prematureejaculationassociatedwithcitalopramwithdrawal. AnnPharmacother. 2003;37(12):1804-6.
Peugh J, Belenko S. Alcohol, drugsandsexualfunction: a review. J PsychoactiveDrugs. 2001;33(3):223-32.
Schapiro B. PrematureEjaculation: Review of 1,130 Cases. J NervMentDis. 1944;100(5):543.
Jannini EA, Burri A, Jern P, Novelli G. Genetics of Human SexualBehavior: WhereWeAre, WhereWeAreGoing. SexMedRev. 2015;3(2):65–77.
Jern P. TwinStudiesandQuantitative Genetics in PrematureEjaculationResearch. Içinde: PrematureEjaculation [Internet]. Springer, Milano; 2013 [kaynak 14 Ocak 2018]. s. 125–31. Available at: https://link.springer.com/ chapter/10.1007/978-88-470-2646-9_10
Janssen PKC, Bakker SC, Réthelyi J, Zwinderman AH, Touw DJ, Olivier B, vd. SerotoninTransporterPromoterRegion (5-HTTLPR) Polymorphism is AssociatedwiththeIntravaginalEjaculationLatency Time in Dutch Men withLifelongPrematureEjaculation. J SexMed. 2009;6(1):276–84.
Luo S, Wang F, Xie Z, Huang X, Lu Y. [Study on thecorrelation of the 5-HTTLPR polymorphismwithprematureejaculation in Han Chinesepopulation]. Beijing Da XueXueBao. 2011;43(4):514–8.
Jannini EA, Ciocca G, Limoncin E, Mollaioli D, DiSante S, Gianfrilli D, vd. Prematureejaculation: oldstory, newinsights. Fertil Steril. 2015;104(5):1061–73.
Screponi E, Carosa E, Stasi SMD, Pepe M, Carruba G, Jannini EA. Prevalence of chronicprostatitis in men withprematureejaculation. Urology. 2001;58(2):198– 202.
Colpi G, Weidner W, Jungwirth A, Pomerol J, Papp G, Hargreave T, vd. EAU Guidelines on EjaculatoryDysfunction. EurUrol. 2004;46(5):555–8.
Jannini EA, Lenzi A. Ejaculatorydisorders: epidemiologyandcurrentapproachestodefinition, classificationandsubtyping. World J Urol. 2005;23(2):68–75.
Corona G, Petrone L, Mannucci E, Jannini EA, Mansani R, Magini A, vd. PsychoBiologicalCorrelates of RapidEjaculation in PatientsAttending an AndrologicUnitforSexualDysfunctions. EurUrol. 2004;46(5):615–22.
Jannini EA, Lombardo F, Lenzi A. Correlationbetweenejaculatoryanderectiledysfunction. Int J Androl. 2005;28:40–5.
Ciocca G, Limoncin E, Mollaioli D, Gravina GL, Carosa E, Sante SD, vd. SIAMS survey on sexologicalscreeningduringtheassistedreproductivetechnologies in Italy. J EndocrinolInvest. 2015;38(9):999– 1005.
Jannini EA, McMahon C. PrematureEjaculation. Italia: Springer-Verlag; 2013.
Maggi M, Heiselman D, Knorr J, Iyengar S, Paduch DA, Donatucci CF. Impact of Testosterone Solution 2% on EjaculatoryDysfunction in Hypogonadal Men. J SexMed. 2016;13(8):1220–6.
Paduch DA, Polzer PK, Ni X, Basaria S. TestosteroneReplacement in Androgen-Deficient Men WithEjaculatoryDysfunction: A RandomizedControlled Trial. J ClinEndocrinolMetab. 2015;100(8):2956–62.
Benz AE, Ausländer J. [Psychoanalyticallyorientedshort-termpsychotherapyforimpotenceandprematureejaculation]. Psyche (Stuttg). 1979;33(5):395–406.
O’Connor JF. Effectiveness of psychologicaltreatment of humansexualdysfunction. ClinObstetGynecol. 1976;19(2):449–64.
Limoncin E, Tomassetti M, Gravina GL, Ciocca G, Carosa E, Sante SD, vd. PrematureEjaculationResults in FemaleSexualDistress: StandardizationandValidation of a New DiagnosticToolforSexualDistress. J Urol. 2013;189(5):1830– 5.
Althof SE. What’s New in SexTherapy (CME). J SexMed. 2010;7(1):5–13.
Althof SE, McMahon CG, Waldinger MD ve ark. An update of the International Society of SexualMedicine’sguidelinesforthediagnosisandtreatment of prematureejaculation (PE). J SexMed 2014;11(6):1392-422.
Waldinger MD. Prematureejaculation: Definition anddrugtreatment. Drugs 2007; 67:547–68
McMahon CG, Althof SE, Kaufman JM ve ark. Efficacyandsafety of dapoxetineforthetreatment of prematüre ejaculation: Integratedanalysis of resultsfromfivephase 3 trials. J SexMed 2011; 8:524–39
McMahon CG, Giuliano F, Dean J ve ark. Efficacyandsafety of dapoxetine in men withprematureejaculationandconcomitanterectiledysfunctiontreatedwith a phosphodiesterasetype 5 inhibitor: Randomized, placebocontrolled, phase III study. J SexMed 2013;10:2312–25.
Porst H, McMahon C, Althof S ve ark. Baselinecharacteristicsandtreatmentoutcomesfor men withacquiredorlifelongprematureejaculationwithmildornoerectiledysfunction: Integratedanalysis of twophase III dapoxetinetrials. J SexMed 2010;7:2231–42.
McMahon CG, McMahon CN, Leow LJ ve ark. Efficacy of type-5 phosphodiesteraseinhibitors in thedrugtreatment of prematüre ejaculation: a systematicreview. BJU Int 2006; 98(2):259-72.
Referanslar
AmericaPsychiatricAssociation. Diagnosticand Statistical Manuel of MentalDisordersFifth Edition. Arlington, VA. 2013.
Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotenceanditsmedicalandpsychosocialcorrelates: results of the Massachusetts Male AgingStudy. TheJournal of urology. 1994;151(1):54– 61.
Braun M, Wassmer G, Klotz T, Reifenrath B, Mathers M, Engelmann U. Epidemiology of erectiledysfunction: results of the ‘Cologne Male Survey’. International journal of impotenceresearch. 2000;12(6):305–11.
Akkus E, Kadioglu A, Esen A, Doran S, Ergen A, Anafarta K, et al. Prevalenceandcorrelates of erectiledysfunction in Turkey: a population-basedstudy. Europeanurology. 2002;41(3):298–304.
Kaplan H. ThePsychosexual Evaluation. Kaplan HS(ed). The Evaluation of SexualDisorders. New York, Brunne/Mazelinc. 1983/23–25.
Shamloul R, Ghanem H. Erectiledysfunction. Lancet. 2013;381 (9861):153–65.
Simopoulos EF, Trinidad AC. Male erectiledysfunction: integratingpsychopharmacologyandpsychotherapy. General hospitalpsychiatry. 2013;35(1):33–8.
Melnik T, Abdo C.G. Psychogenicerectiledysfunction. Comparativestudy of threetherapeuticapproaches. J SexMaritalTher. 2005;31:243–255.
Kapella, Olaf et Stahlhart: MännerunderektileDysfunktion Publisher: Wien: Ö sterreichischesInstitutfü r Familienforschung, [2003]
Stief, C. G.:ErektileDysfunktion: DiagnostikundTherapie, Berlin; New York: Springer, c1997
Thomas Meißner: Werschlankbleibt, hält im AlterseinenTestosteronSpiegel. Der Testosteron-Spiegel sinktbeiMännernnichtzwangsläufi g mit dem Alter. Aber: VieleKomorbiditätengehen mit Testosteronmangeleinher. In: ÄrzteZeitungvom 27. April 2010. AWMF S1-Leitlinie ErektileDysfunkti on (PDF; 1 MB)
I. Motil, I. Kubis et al.:Treatment of VasculogenicErectileDysfunctionwith Piezowave2 Device. In: Advances in SexualMedicine. Band 6, Nr. 2, April 2016, doi:10.4236/asm.2016.62002
EuropäischeGesundheitsbehörde (EMA): Europeanpublicassessmentreport (EPAR) forSpedra - avanafi l. Auf: ema.europa.eu abgerufen am 11. Februar 2014.
DeutscheApothekerZeitung (DAZ): ErektileDysfunktion - Neuer PDE5- HemmerAvanafi l Auf: deutsche-apotheker-zeitung.deabgerufen am 11. Februar 2014.
K. E. HatzimouraƟdis, E. Wespe et al.:Guidelines on malesexualdysfunction: erectiledysfuntionandprematureejaculation. In: EuropeanUrology. 2010, Bd. 57, Nr. 5, S. 804–814, PMID 20189712, doi:10.1016/j. eururo.2010.02.020 (PDF-Datei, VollständigeFassung der Leitlinien).
Waldinger MD, Hengeveld MW, Zwinderman AH. Paroxetinetreatment of prematureejaculation: a double-blind, randomized, placebo-controlledstudy. Am J Psychiatry. 1994;151(9):1377-9
Waldinger MD, Schweitzer DH. Theuse of oldandrecent DSM definitions of prematureejaculation in observationalstudies: a contributiontothepresentdebatefor a newclassification of PE in the DSM-V. J SexMed. 2008;5(5):1079- 87.
Serefoglu EC, Yaman O, Cayan S ve ark. Prevalence of thecomplaint of ejaculatingprematurelyandthefourprematureejaculationsyndromes: resultsfromtheTurkishSociety of AndrologySexualHealthSurvey. J SexMed. 2011;8(2):540- 8.
Waldinger MD, Quinn P, Dilleen M ve ark. A multinationalpopulationsurvey of intravaginalejaculationlatency time. J SexMed. 2005;2(4):492-7.
Jannini EA, Lombardo F, Lenzi A. Correlationbetweenejaculatoryanderectiledysfunction. Int J Androl. 2005;28 Suppl2:40-5
Screponi E, Carosa E, DiStasi SM ve ark. Prevalence of chronicprostatitis in men withprematureejaculation. Urology. 2001;58(2):198-202.
Carani C, Isidori AM, Granata A ve ark. Multicenterstudy on theprevalence of sexualsymptoms in malehypo- andhyperthyroidpatients. J ClinEndocrinolMetab. 2005;90(12):6472-9.
Hartmann U, Schedlowski M, Krüger TH. Cognitiveandpartner-relatedfactors in rapidejaculation: differencesbetweendysfunctionalandfunctional men. World J Urol. 2005;23(2):93-101.
Chekuri V, Gerber D, Brodie A, Krishnadas R. Prematureejaculationandothersexualdysfunctions in opiatedependent men receivingmethadonesubstitutiontreatment. AddictBehav. 2012;37(1):124-6.
Adson DE, Kotlyar M. Prematureejaculationassociatedwithcitalopramwithdrawal. AnnPharmacother. 2003;37(12):1804-6.
Peugh J, Belenko S. Alcohol, drugsandsexualfunction: a review. J PsychoactiveDrugs. 2001;33(3):223-32.
Schapiro B. PrematureEjaculation: Review of 1,130 Cases. J NervMentDis. 1944;100(5):543.
Jannini EA, Burri A, Jern P, Novelli G. Genetics of Human SexualBehavior: WhereWeAre, WhereWeAreGoing. SexMedRev. 2015;3(2):65–77.
Jern P. TwinStudiesandQuantitative Genetics in PrematureEjaculationResearch. Içinde: PrematureEjaculation [Internet]. Springer, Milano; 2013 [kaynak 14 Ocak 2018]. s. 125–31. Available at: https://link.springer.com/ chapter/10.1007/978-88-470-2646-9_10
Janssen PKC, Bakker SC, Réthelyi J, Zwinderman AH, Touw DJ, Olivier B, vd. SerotoninTransporterPromoterRegion (5-HTTLPR) Polymorphism is AssociatedwiththeIntravaginalEjaculationLatency Time in Dutch Men withLifelongPrematureEjaculation. J SexMed. 2009;6(1):276–84.
Luo S, Wang F, Xie Z, Huang X, Lu Y. [Study on thecorrelation of the 5-HTTLPR polymorphismwithprematureejaculation in Han Chinesepopulation]. Beijing Da XueXueBao. 2011;43(4):514–8.
Jannini EA, Ciocca G, Limoncin E, Mollaioli D, DiSante S, Gianfrilli D, vd. Prematureejaculation: oldstory, newinsights. Fertil Steril. 2015;104(5):1061–73.
Screponi E, Carosa E, Stasi SMD, Pepe M, Carruba G, Jannini EA. Prevalence of chronicprostatitis in men withprematureejaculation. Urology. 2001;58(2):198– 202.
Colpi G, Weidner W, Jungwirth A, Pomerol J, Papp G, Hargreave T, vd. EAU Guidelines on EjaculatoryDysfunction. EurUrol. 2004;46(5):555–8.
Jannini EA, Lenzi A. Ejaculatorydisorders: epidemiologyandcurrentapproachestodefinition, classificationandsubtyping. World J Urol. 2005;23(2):68–75.
Corona G, Petrone L, Mannucci E, Jannini EA, Mansani R, Magini A, vd. PsychoBiologicalCorrelates of RapidEjaculation in PatientsAttending an AndrologicUnitforSexualDysfunctions. EurUrol. 2004;46(5):615–22.
Jannini EA, Lombardo F, Lenzi A. Correlationbetweenejaculatoryanderectiledysfunction. Int J Androl. 2005;28:40–5.
Ciocca G, Limoncin E, Mollaioli D, Gravina GL, Carosa E, Sante SD, vd. SIAMS survey on sexologicalscreeningduringtheassistedreproductivetechnologies in Italy. J EndocrinolInvest. 2015;38(9):999– 1005.
Jannini EA, McMahon C. PrematureEjaculation. Italia: Springer-Verlag; 2013.
Maggi M, Heiselman D, Knorr J, Iyengar S, Paduch DA, Donatucci CF. Impact of Testosterone Solution 2% on EjaculatoryDysfunction in Hypogonadal Men. J SexMed. 2016;13(8):1220–6.
Paduch DA, Polzer PK, Ni X, Basaria S. TestosteroneReplacement in Androgen-Deficient Men WithEjaculatoryDysfunction: A RandomizedControlled Trial. J ClinEndocrinolMetab. 2015;100(8):2956–62.
Benz AE, Ausländer J. [Psychoanalyticallyorientedshort-termpsychotherapyforimpotenceandprematureejaculation]. Psyche (Stuttg). 1979;33(5):395–406.
O’Connor JF. Effectiveness of psychologicaltreatment of humansexualdysfunction. ClinObstetGynecol. 1976;19(2):449–64.
Limoncin E, Tomassetti M, Gravina GL, Ciocca G, Carosa E, Sante SD, vd. PrematureEjaculationResults in FemaleSexualDistress: StandardizationandValidation of a New DiagnosticToolforSexualDistress. J Urol. 2013;189(5):1830– 5.
Althof SE. What’s New in SexTherapy (CME). J SexMed. 2010;7(1):5–13.
Althof SE, McMahon CG, Waldinger MD ve ark. An update of the International Society of SexualMedicine’sguidelinesforthediagnosisandtreatment of prematureejaculation (PE). J SexMed 2014;11(6):1392-422.
Waldinger MD. Prematureejaculation: Definition anddrugtreatment. Drugs 2007; 67:547–68
McMahon CG, Althof SE, Kaufman JM ve ark. Efficacyandsafety of dapoxetineforthetreatment of prematüre ejaculation: Integratedanalysis of resultsfromfivephase 3 trials. J SexMed 2011; 8:524–39
McMahon CG, Giuliano F, Dean J ve ark. Efficacyandsafety of dapoxetine in men withprematureejaculationandconcomitanterectiledysfunctiontreatedwith a phosphodiesterasetype 5 inhibitor: Randomized, placebocontrolled, phase III study. J SexMed 2013;10:2312–25.
Porst H, McMahon C, Althof S ve ark. Baselinecharacteristicsandtreatmentoutcomesfor men withacquiredorlifelongprematureejaculationwithmildornoerectiledysfunction: Integratedanalysis of twophase III dapoxetinetrials. J SexMed 2010;7:2231–42.
McMahon CG, McMahon CN, Leow LJ ve ark. Efficacy of type-5 phosphodiesteraseinhibitors in thedrugtreatment of prematüre ejaculation: a systematicreview. BJU Int 2006; 98(2):259-72.