Diyabetik Maküler Ödem Tedavisinde Eşik Altı Mikropulse Lazerin Yeri

Grey RH, Burns-Cox CJ, Hughes A. Blind and partial sight registration in Avon. Br J Ophthalmol; 73: 88-94 (1989).

Klein R, Klein BE, Moss SE. Visual impairment in diabetes. Ophthalmology; 91:1-9 (1984).

Teo, Z.L.; Tham, Y.C.; Yu, M.; Chee, M.L.; Rim, T.H.; Cheung, N.; Bikbov, M.M.; Wang, Y.X.; Tang, Y.; Lu, Y.; et al. Global Prevalence of Diabetic Retinopathy and Projection of Burden through 2045: Systematic Review and Meta-Analysis. Ophthalmology 2021, 128, 1580–1591.

Schmidt-Erfurth, U.; Garcia-Arumi, J.; Bandello, F.; Berg, K.; Chakravarthy, U.; Gerendas, B.S.; Jonas, J.; Larsen, M.; Tadayoni, R.; Loewenstein, A. Guidelines for the Management of Diabetic Macular Edema by the European Society of Retina Specialists (EURETINA). Ophthalmologica 2017, 237, 185–222.

Grzybowski, A.; Markeviciute, A.; Zemaitiene, R. Treatment of Macular Edema in Vascular Retinal Diseases: A 2021 Update. J. Clin. Med. 2021, 10, 5300.

Sun, J.K.; Jampol, L.M. The Diabetic Retinopathy Clinical Research Network (DRCR.Net) and Its Contributions to the Treatment of Diabetic Retinopathy Keywords Diabetic Retinopathy Clinical Research Network Proliferative Diabetic Retinopathy Panretinal Photocoagulation Diabetic Macular Edema. Ophthalmic Res. 2019, 62, 225–230.

7.Everett L.A., Paulus Y.M. Laser Therapy in the Treatment of Diabetic Retinopathy and Diabetic Macular Edema. Curr. Diab Rep. 2021;21:1–12. doi: 10.1007/s11892-021-01403-6.

Photocoagulation for Diabetic Macular Edema. Early Treatment Diabetic Retinopathy Study Report Number 1. Early Treatment Diabetic Retinopathy Study Research Group. [(accessed on 22 October 2022)]

Sivaprasad S., Elagouz M., McHugh D., Shona O., Dorin G. Micropulsed Diode Laser Therapy: Evolution and Clinical Applications. Surv. Ophthalmol. 2010;55:516–530. doi: 10.1016/j.survophthal.2010.02.005

Luttrull J.K., Dorin G. Subthreshold Diode Micropulse Laser Photocoagulation (SDM) as Invisible Retinal Phototherapy for Diabetic Macular Edema: A Review. Curr. Diabetes Rev. 2012;8:274–284. doi: 10.2174/157339912800840523. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Luttrull J.K., Sinclair S.H. Safety of Transfoveal Subthreshold Diode Micropulse Laser for Fovea-Involving Diabetic Macular Edema in Eyes with Good Visual Acuity. Retina. 2014;34:2010–2020. doi: 10.1097/IAE.0000000000000177.

Gawęcki M. Micropulse Laser Treatment of Retinal Diseases. J. Clin. Med. 2019;8:242. doi: 10.3390/jcm8020242.

Donati M.C., Murro V., Mucciolo D.P., Giorgio D., Cinotti G., Virgili G., Rizzo S. Subthreshold Yellow Micropulse Laser for Treatment of Diabetic Macular Edema: Comparison between Fixed and Variable Treatment Regimen. Eur. J. Ophthalmol. 2021;31:1254–1260. doi: 10.1177/1120672120915169.

Zas M., Cotic M., Wu M., Wu A., Wu L. Macular Laser Photocoagulation in the Management of Diabetic Macular Edema: Still Relevant in 2020? Taiwan J. Ophthalmol. 2020;10:87–94. doi: 10.4103/tjo.tjo_16_20.

Mansouri A., Sampat K.M., Malik K.J., Steiner J.N., Glaser B.M. Medscape. Efficacy of subthreshold micropulse laser in the treatment of diabetic macular edema is influenced by pre-treatment central foveal thickness. Eye. 2014;28:1418–1424. doi: 10.1038/eye.2014.264.

Inagaki K., Ohkoshi K., Ohde S., Deshpande G.A., Ebihara N., Murakami A. Comparative Efficacy of Pure Yellow (577-Nm) and 810-Nm Subthreshold Micropulse Laser Photocoagulation Combined with Yellow (561–577-Nm) Direct Photocoagulation for Diabetic Macular Edema. Jpn. J. Ophthalmol. 2015;59:21–28. doi: 10.1007/s10384-014-0361-1. [PubMed] [CrossRef] [Google Scholar]

Kikushima W., Shijo T., Furuhata Y., Sakurada Y., Kashiwagi K. Comparison of the 1-Year Visual and Anatomical Outcomes between Subthreshold Red (670 Nm) and Yellow (577 Nm) Micro-Pulse Laser Treatment for Diabetic Macular Edema. Pharmaceuticals. 2021;14:1100. doi: 10.3390/ph14111100.

Friberg T.R., Karatza E.C. The treatment of macular disease using a micropulsed and continuous wave 810-nm diode laser. Opthalmology. 1997;104:2030–2038. doi: 10.1016/S0161-6420(97)30061-X.

Stanga P.E., Reck A.C., Hamilton A.M. Micropulse laser in the treatment of diabetic macular edema. Semin Ophthalmol. 1999;14:210–213. doi: 10.3109/08820539909069539.

Moore S.M., Chao D.L. Application of subthreshold laser therapy in retinal diseases: A review. Expert Rev. Ophthalmol. 2018;13:311–320. doi: 10.1080/17469899.2018.1555035.

Sramek C., Mackanos M., Spitler R., Leung L.S., Nomoto H., Contag C.H., Palanker D. Non-damaging retinal phototherapy: Dynamic range of heat shock protein expression. Invest. Ophthalmol. Vis. Sci. 2011;52:1780–1787. doi: 10.1167/iovs.10-5917.

Dorin G. Evolution of retinal laser therapy: Minimum intensity photocoagulation (MIP). Can the laser heal the retina without harming it? Semin. Ophthalmol. 2004;19:62–68. doi: 10.1080/08820530490884173.

Midena E., Bini S., Frizziero L., Pilotto E., Esposito G., Micera A. Aqueous humour concentrations of PEDF and Erythropoietin are not influenced by subthreshold micropulse laser treatment of diabetic macular edema. Biosci. Rep. 2019;39:BSR20190328. doi: 10.1042/BSR20190328.

Funatsu H., Yamashita H., Noma H., Mimura T., Nakamura S., Sakata K., Hori S. Aqueous humor levels of cytokines are related to vitreous levels and progression of diabetic retinopathy in diabetic patients. Graefes Arch. Clin. Exp. Ophthalmol. 2005;243:3–8. doi: 10.1007/s00417-004-0950-7.

Ponnalagu M., Subramani M., Jayadev C., Shetty R., Das D. Retinal pigment epithelium-secretome: A diabetic retinopathy perspective. Cytokine. 2017;95:126–135. doi: 10.1016/j.cyto.2017.02.013. [PubMed] [CrossRef] [Google Scholar]

Garcia-Ramírez M., Hernández C., Ruiz-Meana M., Villarroel M., Corraliza L., García-Dorado D., Simó R. Erythropoietin protects retinal pigment epithelial cells against the increase of permeability induced by diabetic conditions: Essential role of JAK2/ PI3K signaling. Cell. Signal. 2011;23:1596–1602. doi: 10.1016/j.cellsig.2011.05.011.

Jonas J.B., Neumaier M. Erythropoietin levels in aqueous humour in eyes with exudative age-related macular degeneration and diabetic retinopathy. Clin. Exp. Ophthalmol. 2007;35:186–187. doi: 10.1111/j.1442-9071.2006.01437.x.

Midena E., Bini S., Martini F., Enrica C., Pilotto E., Micera A., Esposito G., Vujosevic S. Changes of Aqueous Humor Müller Cells’ Biomarkers In Human Patients Affected By Diabetic Macular Edema After Subthreshold Micropulse Laser Treatment. Retina. 2020;40:126–134. doi: 10.1097/IAE.0000000000002356.

Vujosevic S., Micera A., Bini S., Berton M., Esposito G., Midena E. Aqueous Humor Biomarkers of Müller Cell Activation in Diabetic Eyes. Invest. Ophthalmol. Vis. Sci. 2015;56:3913–3918. doi: 10.1167/iovs.15-16554.

Tackenberg M.A., Tucker B.A., Swift J.S., Jiang C., Redenti S., Greenberg K.P., Flannery J.G., Reichenbach A., Young M.J. Müller cell activation, proliferation and migration following laser injury. Mol. Vis. 2009;15:1886–1896.

Karlstetter M., Scholz R., Rutar M., Wong W.T., Provis J.M., Langmann T. Retinal microglia: Just bystander or target for therapy? Prog. Retin. Eye Res. 2014;45:30–57. doi: 10.1016/j.preteyeres.2014.11.004.

Midena E., Torresin T., Velotta E., Pilotto E., Parrozzani R., Frizziero L. OCT Hyperreflective Retinal Foci in Diabetic Retinopathy: A Semi-Automatic Detection Comparative Study. Front. Immunol. 2021;12:613051. doi: 10.3389/fimmu.2021.613051.

Vujosevic S., Toma C., Villani E., Brambilla M., Torti E., Leporati F., Muraca A., Nucci P., De Cilla S. Subthreshold Micropulse Laser in Diabetic Macular Edema: 1-Year Improvement in OCT/OCT-Angiography Biomarkers. Transl. Vis. Sci. Technol. 2020;9:31. doi: 10.1167/tvst.9.10.31.

Keunen J.E.E., Battaglia-Parodi M., Vujosevic S., Luttrull J.K. International Retinal Laser Society Guidelines for Subthreshold Laser Treatment. Transl. Vis. Sci. Technol. 2020;9:15. doi: 10.1167/tvst.9.9.15.

Donati M.C., Murro V., Mucciolo D.P., Giorgio D., Cinotti G., Virgili G., Rizzo S. Subthreshold yellow micropulse laser for treatment of diabetic macular edema: Comparison between fixed and variable treatment regimen. Eur. J. Ophthalmol. 2020;14:1120672120915169. doi: 10.1177/1120672120915169.

Gawęcki M. Micropulse Laser Treatment of Retinal Diseases. J. Clin. Med. 2019;8:242. doi: 10.3390/jcm8020242

Luttrull J.K., Musch D.C., Mainster M.A. Subthreshold diode micropulse photocoagulation for the treatment of clinically significant diabetic macular oedema. Br. J. Ophthalmol. 2005;89:74–80. doi: 10.1136/bjo.2004.051540.

Vujosevic S., Martini F., Longhin E., Convento E., Cavarzeran F., Midena E. Subthreshold micropulse yellow laser versus subthreshold micropulse infrared laser in center-involving diabetic macular edema: Morphologic and Functional Safety. Retina. 2015;35:1594–1603. doi: 10.1097/IAE.0000000000000521.

Lavinsky D., Cardillo J.A., Melo L.A., Jr., Dare A., Farah M.E., Belfort R., Jr. Randomized clinical trial evaluating mETDRS versus normal or high-density micropulse photocoagulation for diabetic macular edema. Invest. Ophthalmol. Vis. Sci. 2011;52:4314–4323. doi: 10.1167/iovs.10-6828.

Figueira J., Khan J., Nunes S., Sivaprasad S., Rosa A., de Abreu J.F., Cunha-Vaz J.G., Chong N.V. Prospective randomised controlled trial comparing sub-threshold micropulse diode laser photocoagulation and conventional green laser for clinically significant diabetic macular oedema. Br. J. Ophthalmol. 2009;93:1341–1344. doi: 10.1136/bjo.2008.146712.

Gao X., Xing D. Molecular mechanisms of cell proliferation induced by low power laser irradiation. J. Biomed. Sci. 2009;16:4. doi: 10.1186/1423-0127-16-4.

Blindbaek S.L., Peto T., Grauslund J. How do we evaluate the role of focal/grid photocoagulation in the treatment of diabetic macular edema? Acta Ophthalmol. 2019;97:339–346. doi: 10.1111/aos.13997.

Luttrull J.K., Spink C.J. Serial optical coherence tomography of subthreshold diode laser micropulse photocoagulation for diabetic macular edema. Ophthalmic Surg. Lasers Imaging. 2006;37:370–377. doi: 10.3928/15428877-20060901-03.

Citirik M. The impact of central foveal thickness on the efficacy of subthreshold micropulse yellow laser photocoagulation in diabetic macular edema. Lasers Med. Sci. 2019;34:907–912. doi: 10.1007/s10103-018-2672-9.

Vujosevic S., Bottega E., Casciano M., Pilotto E., Convento E., Midena E. Microperimetry and Fundus Autofluorescence in Diabetic Macular Edema: Subthreshold Micropulse Diode Laser Versus Modified Early Treatment Diabetic Retinopathy Study Laser Photocoagulation. Retina. 2010;30:908–916. doi: 10.1097/IAE.0b013e3181c96986.

Lois N., Campbell C., Waugh N., Azuara-Blanco A., Maredza M., Mistry H., McAuley D., Acharya N., Aslam T.M., Bailey C., et al. DIAbetic Macular Oedema aNd Diode Subthreshold Micropulse Laser (DIAMONDS): A Randomized Double-Masked Non-Inferiority Clinical Trial. Ophthalmology. 2022;20:122. doi: 10.1016/j.ophtha.2022.08.012.

Fazel F., Bagheri M., Golabchi K., Jahanbani Ardakani H. Comparison of Subthreshold Diode Laser Micropulse Therapy versus Conventional Photocoagulation Laser Therapy as Primary Treatment of Diabetic Macular Edema. J. Curr. Ophthalmol. 2016;28:206–211. doi: 10.1016/j.joco.2016.08.007.

Akhlaghi M., Dehghani A., Pourmohammadi R., Asadpour L., Pourazizi M. Effects of Subthreshold Diode Micropulse Laser Photocoagulation on Treating Patients with Refractory Diabetic Macular Edema. J. Curr. Ophthalmol. 2019;31:157–160. doi: 10.1016/j.joco.2018.11.006.

Akkaya S., Açikalin B., Dogan Y.E., Çoban F. Subthreshold Micropulse Laser versus Intravitreal Anti- VEGF for Diabetic Macular Edema Patients with Relatively Better Visual Acuity. Int. J. Ophthalmol. 2020;13:1606–1611. doi: 10.18240/ijo.2020.10.15.

Lai F.H.P., Chan R.P.S., Lai A.C.H., Tsang S., Woo T.T.Y., Lam R.F., Yuen C.Y.F. Comparison of Two-Year Treatment Outcomes between Subthreshold Micropulse (577 Nm) Laser and Aflibercept for Diabetic Macular Edema. Jpn. J. Ophthalmol. 2021;65:680–688. doi: 10.1007/s10384-021-00846-4.

Elhamid A.H.A. Combined Intravitreal Dexamethasone Implant And Micropulse Yellow Laser For Treatment Of Anti-VEGF Resistant Diabetic Macular Edema. Open Ophthalmol. J. 2017;11:164–172. doi: 10.2174/1874364101711010164.